PomBase maintains two sets of manually curated orthologs: fission yeast (S. pombe) and budding yeast (S. cerevisiae), and fission yeast and human. Both can be queried in the simple search -- for budding yeast, use an ORF name (e.g. YBR160W); for human, use an HGNC-approved gene name (e.g. NCAPG). The complete datasets can also be downloaded.

Orthologs in species other than budding yeast and human can be searched in Compara or YOGY, as described in this FAQ.