SPAC1039.02


Gene Standard NameUnassigned Characterisation Statusconserved_unknown
Systematic IDSPAC1039.02 Feature Typeprotein coding
Synonyms Name Description
Productphosphoprotein phosphatase (predicted) Product Size601aa, 68.07 kDa
Genomic Location Chromosome I, 5448735-5451642 (2908nt); CDS:5449717-5451522 (1806nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
hydrolase activity839
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4208
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationSPAC1039.02ΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologySPAC1039.02ΔNull3092
Target Of
OntologyRelationshipGeneProductReference
FYPO affected by mutation in upf1 ATP-dependent RNA helicase Upf1 PMID:16914721
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons5448735..5451642
mRNA5448735..5451642
5' UTR5448735..5449716PMID:21511999
CDS5449717..5451522
3' UTR5451523..5451642PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00149 Pfam IPR004843 Calcineurin-like phosphoesterase domain, apaH type 49 272 20
PTHR11575 HMMPANTHER IPR006179 5'-Nucleotidase/apyrase 18 482 3
PTHR11575:SF22 HMMPANTHER 18 482 3
3.60.21.10 Gene3D IPR029052 Metallo-dependent phosphatase-like 38 388 23
3.90.780.10 Gene3D IPR008334 5'-Nucleotidase, C-terminal 389 600 3
SSF56300 SuperFamily IPR029052 Metallo-dependent phosphatase-like 41 379 22
SSF55816 SuperFamily IPR008334 5'-Nucleotidase, C-terminal 382 596 3
PIRSF017316 PIRSF IPR014485 Predicted phosphoesterase, C1039.02 type 4 600 3
SignalP-noTM signalp 1 24 212

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279

Protein Properties

Ave. residue weight 113.25 Da
Charge -18.50
Isoelectric point 4.75
Molecular weight 68.07 kDa
Number of residues 601
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3723.38during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
70314.53during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
7.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi only620
conserved in fungi4604
conserved in eukaryotes4516
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withatb2tubulin alpha 2 Negative GeneticPMID:22681890
negative genetic interaction withatg13autophagy associated protein kinase regulatory subunit Atg13 Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:22681890
negative genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
negative genetic interaction witheso1sister chromatid cohesion protein/DNA polymerase eta Eso1 fusion protein Negative GeneticPMID:23050226
negative genetic interaction withgim3prefoldin subunit 4, Gim3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Positive GeneticPMID:22681890
negative genetic interaction withphp3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
negative genetic interaction withsck2serine/threonine protein kinase Sck2 Negative GeneticPMID:24463365
negative genetic interaction withSPCC70.06nuclear export factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtoc1Tor complex Tor2 interacting protein 1 Negative GeneticPMID:22681890
negative genetic interaction withusp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
negative genetic interaction withxap5xap-5-like protein Negative GeneticPMID:24957674
External References
Database Identifier Description
NBRP SPAC1039.02 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1039.02 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1039.02 BioGRID Interaction Datasets
Expression Viewer SPAC1039.02 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1039.02 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1039.02 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1039.02 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1039.02 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1039.02 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1039.02 Cell Cycle Data
GEO SPAC1039.02 GEO profiles
PInt SPAC1039.02 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1039.02 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1039.02 Fission yeast phenotypic data & analysis
SPD / RIKEN36/36E06Orfeome Localization Data
UniProtKB/SwissProtQ9US39Uncharacterized protein C1039.02
ModBaseQ9US39Database of comparative protein structure models
STRINGQ9US39Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594993phosphoprotein phosphatase (predicted)
RefSeq mRNANM_001020424972h- phosphoprotein phosphatase (predicted) (SPAC1039.02), mRNA
European Nucleotide ArchiveBAA87266.1ENA Protein Mapping
European Nucleotide ArchiveCAB63538.1ENA Protein Mapping
UniParcUPI00000695BFUniProt Archive

Literature for SPAC1039.02

Search: Europe PMC or PubMed

Release Version: PomBase:25_50 - 10 Mar 2015