rpp203 (SPAC1071.08)


Gene Standard Namerpp203 Characterisation Statuspublished
Systematic IDSPAC1071.08 Feature Typeprotein coding
Synonymsrla6, rpa2, rpp2-3 Name Description
Product60S acidic ribosomal protein A2 Product Size110aa, 11.11 kDa
Genomic Location Chromosome I, 3869082-3869610 (529nt); CDS:3869145-3869571 (427nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translational elongation193
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationrpp203ΔNull3783

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrpp203ΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
138690823869453
238695483869610

UTRs

Region Coordinates Reference
five_prime_UTR3869082..3869144PMID:21511999
three_prime_UTR3869572..3869610PMID:21511999
mRNA3869082..3869610
exon3869145..3869453,3869548..3869571
intron3869454..3869547
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam IPR001813 Ribosomal protein L10/L12 17 109 7
PTHR21141 HMMPANTHER 1 110 8
MF_01478 hamap IPR027534 Ribosomal protein L12 family 2 110 6
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.04 Da
Charge -16.00
Isoelectric point 3.77
Molecular weight 11.11 kDa
Number of residues 110
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1670
present during mitotic M phaseS100
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S100 PMID:21712547
phosphorylated residue 1923
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
407468during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
393754during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
429037during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
384929during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
141634.78during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
388585during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
60030.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
54during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
3.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000
conserved in metazoa3432
conserved in vertebrates3407
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byhhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
affinity captured byhhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
affinity captured bynak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
positive genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withcaf4CCR4-Not complex subunit Caf4/Mdv1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withcdc18MCM loader Positive GeneticPMID:22681890
negative genetic interaction withckb2CK2 family regulatory subunit Ckb2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Negative GeneticPMID:22681890
negative genetic interaction withcul1cullin 1 Negative GeneticPMID:22681890
positive genetic interaction withelp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
negative genetic interaction withmpr1histidine-containing response regulator phosphotransferase Mpr1 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withmug81ATP-dependent RNA helicase Slh1, human ASCC3 ortholog (predicted) Negative GeneticPMID:22681890
positive genetic interaction withphp3CCAAT-binding factor complex subunit Php3 Positive GeneticPMID:22681890
negative genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:22681890
negative genetic interaction withppk21serine/threonine protein kinase Ppk21 Negative GeneticPMID:22681890
negative genetic interaction withprz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
negative genetic interaction withptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
negative genetic interaction withrap1telomere binding protein Rap1 Negative GeneticPMID:22681890
negative genetic interaction withres1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
positive genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Positive GeneticPMID:22681890
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
negative genetic interaction withsre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:22681890
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withtos4FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC1071.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1071.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1071.08 BioGRID Interaction Datasets
Expression Viewer SPAC1071.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1071.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1071.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1071.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1071.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1071.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1071.08 Cell Cycle Data
GEO SPAC1071.08 GEO profiles
PInt SPAC1071.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1071.08 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1071.08 Fission yeast phenotypic data & analysis
SPD / RIKEN03/03E03Orfeome Localization Data
UniProtKB/SwissProtO1431760S acidic ribosomal protein P2-C
ModBaseO14317Database of comparative protein structure models
STRINGO14317Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59435860S acidic ribosomal protein P2C
RefSeq mRNANM_001019779972h- 60S acidic ribosomal protein P2C (rpp203), mRNA
European Nucleotide ArchiveAJ002734ENA EMBL mapping
European Nucleotide ArchiveCAB59884.1ENA Protein Mapping
UniParcUPI000006AA43UniProt Archive

Literature for rpp203

Search: Europe PMC or PubMed

Release Version: PomBase:25_49 - 02 Feb 2015