rpp203 (SPAC1071.08)


Gene Standard Namerpp203 Characterisation Statuspublished
Systematic IDSPAC1071.08 Feature Typeprotein coding
Synonymsrla6, rpa2, rpp2-3 Name Description
Product60S acidic ribosomal protein A2 Product Size110aa, 11.11 kDa
Genomic Location Chromosome I, 3869082-3869610 (529nt); CDS:3869145-3869571 (427nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000005399GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002182cytoplasmic translational elongationNASGO_REF:0000051193
GO:0006414translational elongationISOSGD:S000005399GO_REF:0000024221
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722319
GO:0022625cytosolic large ribosomal subunitISOSGD:S000005399GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpp203ΔNullPECO:0000005, PECO:0000137PMID:236978063751
Microscopyrpp203ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrpp203ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
138690823869453
238695483869610
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00428 Pfam IPR001813 Ribosomal protein L10/L12 17 109 7
PTHR21141 HMMPANTHER 1 110 8
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 82 96 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 21 32 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 97 108 3
PR00456 PRINTS IPR001859 Trypanosoma cruzi ribosomal protein P2-like 36 47 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 101.04 Da
Charge -16.00
Isoelectric point 3.77
Molecular weight 11.11 kDa
Number of residues 110
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS100PMID:217125471670
present during mitotic M phase
MOD:00696phosphorylated residueNASPMID:195477441922
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
407468during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
393754during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
429037during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
384929during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
141634.78during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
388585during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
60030.7during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
54during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
3.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4599
conserved in eukaryotes4514
conserved in bacteria1002
conserved in metazoa3428
conserved in vertebrates3402
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
pnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Positive GeneticPMID:22681890
mug81ATP-dependent RNA helicase Slh1 (predicted) Negative GeneticPMID:22681890
caf4CCR4-Not complex subunit Caf4/Mdv1 (predicted) Negative GeneticPMID:22681890
elp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
ckb2CK2 family regulatory subunit Ckb2 (predicted) Negative GeneticPMID:22681890
mpr1histidine-containing response regulator phosphotransferase Mpr1 Negative GeneticPMID:22681890
cdc18MCM loader Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
ppk21serine/threonine protein kinase Ppk21 Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:22681890
rap1telomere binding protein Rap1 Negative GeneticPMID:22681890
cul1cullin 1 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
swc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
tos4FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
php3CCAAT-binding factor complex subunit Php3 Positive GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
cpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC1071.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1071.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1071.08 BioGRID Interaction Datasets
Expression Viewer SPAC1071.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1071.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1071.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1071.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1071.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1071.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1071.08 Cell Cycle Data
GEO SPAC1071.08 GEO profiles
PInt SPAC1071.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1071.08 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN03/03E03Orfeome Localization Data
UniProtKB/SwissProtO1431760S acidic ribosomal protein P2-C
ModBaseO14317Database of comparative protein structure models
STRINGO14317Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59435860S acidic ribosomal protein P2C
RefSeq mRNANM_001019779972h- 60S acidic ribosomal protein P2C (rpp203), mRNA
European Nucleotide ArchiveAJ002734ENA EMBL mapping
European Nucleotide ArchiveCAB59884.1ENA Protein Mapping
UniParcUPI000006AA43UniProt Archive

Literature for rpp203

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014