SPAC1093.04c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC1093.04c Feature Typeprotein coding
Synonyms Name Description
ProducttRNA nucleotidyltransferase (predicted) Product Size500aa, 57.55 kDa
Genomic Location Chromosome I, 4618620-4613715 (4906nt); CDS:4618140-4616462 (1679nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005524ATP bindingIEAUniProtKB-KW:KW-0067GO_REF:0000037559
GO:0052929ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activityIEA EC:2.7.7.72GO_REF:00000032
GO:0052928CTP:3'-cytidine-tRNA cytidylyltransferase activityIEA EC:2.7.7.72GO_REF:00000032
GO:0052927CTP:tRNA cytidylyltransferase activityIEA EC:2.7.7.72GO_REF:00000032
GO:0003723RNA bindingIEAUniProtKB-KW:KW-0694GO_REF:0000037628
GO:0004810tRNA adenylyltransferase activityISOSGD:S000000970GO_REF:00000242
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0001680tRNA 3'-terminal CCA additionIEA EC:2.7.7.72GO_REF:00000032
GO:0006400tRNA modificationISOSGD:S000000970GO_REF:000002476
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopySPAC1093.04cΔNullPMID:204732891315
FYPO:0002060viable vegetative cell populationMicroscopySPAC1093.04cΔNullPECO:0000005, PECO:0000137PMID:236978063760

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001511inviable vegetative cell, abnormal cell shape, normal cell size199
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
MicroscopySPAC1093.04cΔNullPECO:0000137, PECO:0000005PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
146186204618360
246182974617997
346179354617353
446172814616668
546166234613715

UTRs

Region Coordinates Reference
five_prime_UTR4618620..4618360,4618297..4618141PMID:21511999
three_prime_UTR4616461..4613715PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01743 Pfam IPR002646 Poly A polymerase, head domain 39 177 2
PF12627 Pfam 204 263 2
PTHR13734:SF5 HMMPANTHER 8 499 2
PTHR13734 HMMPANTHER 8 499 2
1.10.3090.10 Gene3D 174 392 2
3.30.460.10 Gene3D 16 173 11
SSF81301 SuperFamily 27 174 11
SSF81891 SuperFamily 175 487 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.11 Da
Charge 7.00
Isoelectric point 7.48
Molecular weight 57.55 kDa
Number of residues 500
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
3923during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
3643during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
3350during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
4060during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
4009during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
2225.35during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
622.45during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.49during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
1.7during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated432
multiple translational start sites possible2
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3393
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:21436456
External References
Database Identifier Description
NBRP SPAC1093.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1093.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1093.04c BioGRID Interaction Datasets
Expression Viewer SPAC1093.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1093.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1093.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1093.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1093.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1093.04c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1093.04c Cell Cycle Data
GEO SPAC1093.04c GEO profiles
PInt SPAC1093.04c Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz2.7.7.25Integrated relational Enzyme database
Rhea2.7.7.25Annotated reactions database
WikiGene2542977tRNA nucleotidyltransferase (predicted)
EntrezGene2542977tRNA nucleotidyltransferase (predicted)
SPD / RIKEN45/45G10Orfeome Localization Data
UniProtKB/SwissProtQ9UTQ0Putative CCA tRNA nucleotidyltransferase 1
ModBaseQ9UTQ0Database of comparative protein structure models
STRINGQ9UTQ0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594651tRNA nucleotidyltransferase (predicted)
RefSeq mRNANM_001020080972h- tRNA nucleotidyltransferase (predicted) (SPAC1093.04c), mRNA
European Nucleotide ArchiveCAB60249ENA Protein Mapping
European Nucleotide ArchiveCAB60249.2ENA Protein Mapping
UniParcUPI000053FDF5UniProt Archive

Literature for SPAC1093.04c

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014