SPAC1093.04c


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC1093.04c Feature Typeprotein coding
Synonyms Name Description
ProductATP(CTP) tRNA nucleotidyltransferase Cca1 (predicted) Product Size500aa, 57.55 kDa
Genomic Location Chromosome I, 4618620-4613715 (4906nt); CDS:4618140-4616462 (1679nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
ATP binding558
Annotation ExtensionEvidenceWith/FromReference
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity2
Annotation ExtensionEvidenceWith/FromReference
CTP:3'-cytidine-tRNA cytidylyltransferase activity2
Annotation ExtensionEvidenceWith/FromReference
CTP:tRNA cytidylyltransferase activity2
Annotation ExtensionEvidenceWith/FromReference
RNA binding571
Annotation ExtensionEvidenceWith/FromReference
tRNA adenylyltransferase activity2
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
tRNA 3'-terminal CCA addition2
Annotation ExtensionEvidenceWith/FromReference
tRNA modification76
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationSPAC1093.04cΔNull1438

Cell Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell, abnormal cell shape, normal cell sizeSPAC1093.04cΔNull199
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4618620..4618360, 4618297..4617997, 4617935..4617353, 4617281..4616668, 4616623..4613715
mRNA4618620..4613715
5' UTR4618620..4618360, 4618297..4618141PMID:21511999
CDS4618140..4617997, 4617935..4617353, 4617281..4616668, 4616623..4616462
3' UTR4616461..4613715PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01743 Pfam IPR002646 Poly A polymerase, head domain 39 177 2
PF12627 Pfam 204 263 2
PTHR13734 HMMPANTHER 8 499 2
PTHR13734:SF5 HMMPANTHER 8 499 2
3.30.460.10 Gene3D 16 173 11
1.10.3090.10 Gene3D 174 392 2
SSF81891 SuperFamily 175 487 2
SSF81301 SuperFamily 27 174 11

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.11 Da
Charge 7.00
Isoelectric point 7.48
Molecular weight 57.55 kDa
Number of residues 500
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3643during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
4009during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
3923during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
3350during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
622.45during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4060during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
2225.35during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.49during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated433
multiple translational start sites possible2
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in bacteria1001
conserved in metazoa3424
conserved in vertebrates3399
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:21436456
External References
Database Identifier Description
NBRP SPAC1093.04c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1093.04c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1093.04c BioGRID Interaction Datasets
Expression Viewer SPAC1093.04c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1093.04c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1093.04c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1093.04c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1093.04c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1093.04c Transcriptome Viewer (Bähler Lab)
GEO SPAC1093.04c GEO profiles
PInt SPAC1093.04c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1093.04c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1093.04c Fission yeast phenotypic data & analysis
Cyclebase SPAC1093.04c.1 Cell Cycle Data
SPD / RIKEN45/45G10Orfeome Localization Data
IntEnz2.7.7.25Integrated relational Enzyme database
Rhea2.7.7.25Annotated reactions database
UniProtKB/SwissProtQ9UTQ0Putative CCA tRNA nucleotidyltransferase 1
ModBaseQ9UTQ0Database of comparative protein structure models
STRINGQ9UTQ0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594651tRNA nucleotidyltransferase (predicted)
RefSeq mRNANM_001020080972h- tRNA nucleotidyltransferase (predicted) (SPAC1093.04c), mRNA
European Nucleotide ArchiveCAB60249.2ENA Protein Mapping
UniParcUPI000053FDF5UniProt Archive

Literature for SPAC1093.04c

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015