mug134 (SPAC10F6.16)


Gene Standard Namemug134 Characterisation Statusbiological_role_inferred
Systematic IDSPAC10F6.16 Feature Typeprotein coding
Synonymsigo1 Name DescriptionMeiotically Upregulated Gene
ProductmRNA stability protein Igo1 (predicted) Product Size139aa, 15.44 kDa
Genomic Location Chromosome I, 1238896-1240185 (1290nt); CDS:1238896-1239424 (529nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
mRNA stabilization8
Annotation ExtensionEvidenceWith/FromReference
regulation of phosphoprotein phosphatase activity8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytoplasm4209
Annotation ExtensionEvidenceWith/FromReference
cytoplasmic mRNA processing body14
Annotation ExtensionEvidenceWith/FromReference
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
increased cell population growth ratemug134ΔNull247
sensitive to 5-fluorouracilmug134ΔNull271
viable vegetative cell populationmug134ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologymug134ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1238896..1238979, 1239025..1239108, 1239173..1240185
Introns1238980..1239024, 1239109..1239172
mRNA1238896..1240185
CDS1238896..1238979, 1239025..1239108, 1239173..1239424
3' UTR1239425..1240185SPAB1289
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04667 Pfam IPR006760 Endosulphine 25 86 1
PTHR10358 HMMPANTHER 2 134 1
PTHR10358:SF6 HMMPANTHER 2 134 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.09 Da
Charge 8.50
Isoelectric point 10.33
Molecular weight 15.44 kDa
Number of residues 139
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS89
present during mitotic M phaseS31
level fluctuates during mitotic cell cycleS64
present during mitotic M phaseS64
present during mitotic M phaseS102
present during mitotic M phaseS99
S31
Annotation ExtensionEvidenceResidueReference
experimental evidence S31 PMID:24763107
present during mitotic M phase experimental evidence S31 PMID:21712547
present during mitotic M phase experimental evidence S64 PMID:21712547
level fluctuates during mitotic cell cycle experimental evidence S64 PMID:24763107
present during mitotic M phase experimental evidence S89 PMID:21712547
present during mitotic M phase experimental evidence S99 PMID:21712547
present during mitotic M phase experimental evidence S102 PMID:21712547
O-phospho-L-threonine 698
present during mitotic M phaseT92
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T92 PMID:21712547
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9229.33during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
7280.95during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC10F6.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC10F6.16 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC10F6.16 BioGRID Interaction Datasets
Expression Viewer SPAC10F6.16 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC10F6.16 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC10F6.16 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC10F6.16 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC10F6.16 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC10F6.16 Transcriptome Viewer (Bähler Lab)
GEO SPAC10F6.16 GEO profiles
PInt SPAC10F6.16 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC10F6.16 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC10F6.16 Fission yeast phenotypic data & analysis
Cyclebase SPAC10F6.16.1 Cell Cycle Data
SPD / RIKEN05/05D01Orfeome Localization Data
UniProtKB/SwissProtP79058mRNA stability protein mug134
ModBaseP79058Database of comparative protein structure models
STRINGP79058Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593267mRNA stability protein Igo1 (predicted)
RefSeq mRNANM_001018664972h- mRNA stability protein Igo1 (predicted) (mug134), mRNA
European Nucleotide ArchiveAB001289ENA EMBL mapping
European Nucleotide ArchiveCAA15729.1ENA Protein Mapping
UniParcUPI000006C8CCUniProt Archive

Literature for mug134

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015