mug134 (SPAC10F6.16)


Gene Standard Namemug134 Characterisation Statusbiological_role_inferred
Systematic IDSPAC10F6.16 Feature Typeprotein coding
Synonymsigo1 Name DescriptionMeiotically Upregulated Gene
ProductmRNA stability protein Igo1 (predicted) Product Size139aa, 15.44 kDa
Genomic Location Chromosome I, 1238896-1240185 (1290nt); CDS:1238896-1239424 (529nt)

Ensembl Gene Location
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0070314G1 to G0 transitionISOSGD:S000005101GO_REF:00000249
GO:0048255mRNA stabilizationISOSGD:S000005101GO_REF:00000247
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmISOSGD:S000005101GO_REF:00000244201
GO:0000932cytoplasmic mRNA processing bodyISOSGD:S000005101GO_REF:000002416
GO:0005829cytosolIDAPMID:168233722316
GO:0005634nucleusISOSGD:S000005101GO_REF:00000242740
IDAPMID:16823372
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopymug134ΔNullPMID:204732893760
Microscopymug134ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3086
penetrance FYPO_EXT:0000001Microscopymug134ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
112388961238979
212390251239108
312391731240185
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04667 Pfam IPR006760 Endosulphine 25 86 1
PTHR10358:SF6 HMMPANTHER 2 134 1
PTHR10358 HMMPANTHER 2 134 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.09 Da
Charge 8.50
Isoelectric point 10.33
Molecular weight 15.44 kDa
Number of residues 139
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS102PMID:217125471663
present during mitotic M phase
present during mitotic M phaseS99PMID:21712547
present during mitotic M phaseS89PMID:21712547
S31PMID:24763107
level fluctuates during mitotic cell cycleS64PMID:24763107
present during mitotic M phaseS64PMID:21712547
present during mitotic M phaseS31PMID:21712547
MOD:00047O-phospho-L-threonineT92PMID:21712547682
present during mitotic M phase
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
7280.95during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
9229.33during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
2.7during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in eukaryotes only2487
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC10F6.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC10F6.16 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC10F6.16 BioGRID Interaction Datasets
Expression Viewer SPAC10F6.16 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC10F6.16 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC10F6.16 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC10F6.16 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC10F6.16 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC10F6.16 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC10F6.16 Cell Cycle Data
GEO SPAC10F6.16 GEO profiles
PInt SPAC10F6.16 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2542961endosulphine family protein
EntrezGene2542961endosulphine family protein
SPD / RIKEN05/05D01Orfeome Localization Data
UniProtKB/SwissProtP79058mRNA stability protein mug134
ModBaseP79058Database of comparative protein structure models
STRINGP79058Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593267endosulphine family protein
RefSeq mRNANM_001018664972h- endosulphine family protein (mug134), mRNA
European Nucleotide ArchiveAB001289ENA EMBL mapping
European Nucleotide ArchiveBAA19234ENA Protein Mapping
European Nucleotide ArchiveCAA15729ENA Protein Mapping
European Nucleotide ArchiveCAA15729.1ENA Protein Mapping
UniParcUPI000006C8CCUniProt Archive

Literature for mug134

Search: Europe PMC or PubMed

Release Version: PomBase:22_44 - 08 Jul 2014