mug134 (SPAC10F6.16)

Gene Standard Namemug134 Characterisation Statusbiological_role_inferred
Systematic IDSPAC10F6.16 Feature Typeprotein coding
Synonymsigo1 Name DescriptionMeiotically Upregulated Gene
ProductmRNA stability protein Igo1 (predicted) Product Size139aa, 15.44 kDa
Genomic Location Chromosome I, 1238896-1240185 (1290nt); CDS:1238896-1239424 (529nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
G1 to G0 transition9
Annotation ExtensionEvidenceWith/FromReference
mRNA stabilization8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytoplasmic mRNA processing body15
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopymug134ΔNullPECO:0000005, PECO:0000137PMID:236978063759

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopymug134ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04667 Pfam IPR006760 Endosulphine 25 86 1
PTHR10358 HMMPANTHER 4 136 1
PTHR10358:SF3 HMMPANTHER 4 136 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.09 Da
Charge 8.50
Isoelectric point 10.33
Molecular weight 15.44 kDa
Number of residues 139

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS89PMID:217125471670
present during mitotic M phase
present during mitotic M phaseexperimental evidenceS99PMID:21712547
present during mitotic M phaseexperimental evidenceS102PMID:21712547
present during mitotic M phaseexperimental evidenceS31PMID:21712547
present during mitotic M phaseexperimental evidenceS64PMID:21712547
level fluctuates during mitotic cell cycleexperimental evidenceS64PMID:24763107
experimental evidenceS31PMID:24763107
MOD:00047O-phospho-L-threonineexperimental evidenceT92PMID:21712547692
present during mitotic M phase
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9229.33during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
7280.95during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.82during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC10F6.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC10F6.16 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC10F6.16 BioGRID Interaction Datasets
Expression Viewer SPAC10F6.16 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC10F6.16 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC10F6.16 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC10F6.16 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC10F6.16 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC10F6.16 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC10F6.16 Cell Cycle Data
GEO SPAC10F6.16 GEO profiles
PInt SPAC10F6.16 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC10F6.16 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC10F6.16 Fission yeast phenotypic data & analysis
SPD / RIKEN05/05D01Orfeome Localization Data
UniProtKB/SwissProtP79058mRNA stability protein mug134
ModBaseP79058Database of comparative protein structure models
STRINGP79058Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593267mRNA stability protein Igo1 (predicted)
RefSeq mRNANM_001018664972h- mRNA stability protein Igo1 (predicted) (mug134), mRNA
European Nucleotide ArchiveAB001289ENA EMBL mapping
European Nucleotide ArchiveCAA15729.1ENA Protein Mapping
UniParcUPI000006C8CCUniProt Archive

Literature for mug134

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Release Version: PomBase:23_47 - 27 Oct 2014