SPAC11D3.14c

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC11D3.14c Gene Start135736
Synonyms Gene End131190
Product5-oxoprolinase (ATP-hydrolizing) (predicted) Gene Length4547
Feature Typeprotein coding CDS Start135101
Name Description CDS End131319
Characterisation Statusbiological_role_inferred CDS Length3783

Ensembl Gene Location
  1. SPAC11D3.10
  2. SPAC11D3.11c
  3. SPAC11D3.13
  4. SPAC11D3.14c
  5. SPNCRNA.609
  6. SPNCRNA.147
  7. SPAC11D3.15
  8. SPNCRNA.610
  9. SPAC11D3.16c
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPAC11D3.14cdelta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:00171685-oxoprolinase (ATP-hydrolyzing) activityISOSGD:S000001698GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006749glutathione metabolic processISOSGD:S000001698GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1135736131190

References

Region Start End Reference
three_prime_UTR131318131190PMID:21511999
five_prime_UTR135736135102PMID:21511999
three_prime_UTR131318131190PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF05378 IPR008040 Pfam Hydantoinaseoxoprolinase, N-terminal 6 211 2
PF02538 IPR003692 Pfam Hydantoinase B/oxoprolinase 730 1257 2
PF01968 IPR002821 Pfam Hydantoinase/oxoprolinase 230 523 2
PTHR11365 hmmpanther 1 1256 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.15 Da
Charge -9.00
Isoelectric point 5.95
Molecular weight 138.78 kDa
Number of residues 1260
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide4037.5PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.9PMID:23101633
Genome Organisation
DescriptionQualifierReference
divergent duplication
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in metazoa
conserved in vertebrates
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ppe1serine/threonine protein phosphatase Ppe1 Negative GeneticPMID:22681890
amk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Positive GeneticPMID:22681890
ssp2serine/threonine protein kinase Ssp2 Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC11D3.14c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC11D3.14c Retrieval of eukaryotic orthologs
BioGrid SPAC11D3.14c BioGRID Interaction Datasets
Bähler Lab SPAC11D3.14c Cell Cycle Expression Profile
Bähler Lab SPAC11D3.14c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC11D3.14c Pheromone response/mating expression profiles
Bähler Lab SPAC11D3.14c Environmental stress expression profiles
Bähler Lab SPAC11D3.14c Bähler Lab Transcriptome Viewer
Cyclebase SPAC11D3.14c Cell Cycle Data
PInt SPAC11D3.14c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC11D3.14c Entrez Gene
WikiGene2542986oxoprolinase (predicted)
EntrezGene2542986oxoprolinase (predicted)
SPD / RIKEN39/39C08Orfeome Localization Data
UniProtKB/SwissProtQ10093Uncharacterized protein C11D3.14c
ModBaseQ10093Database of comparative protein structure models
Pfam Protein DomainsQ10093Pfam Domain Arrangement
RefSeq PeptideNP_592809oxoprolinase (predicted)
RefSeq mRNANM_001018209972h- oxoprolinase (predicted) (SPAC11D3.14c), mRNA
European Nucleotide ArchiveCAA92315ENA Protein Mapping
UniParcUPI000013A13BUniProt Archive

Literature for SPAC11D3.14c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013