pcs1 (SPAC11E3.03)

Synonyms ChromosomeI
Productchromosome segregation protein Pcs1 Gene Start5286053
Feature Typeprotein coding Gene End5287290
Name Description CDS Start5286130
Characterisation Statuspublished CDS End5287055

Ensembl Gene Location
swr1 SPAC11E3.02c > pcs1 < ubc13 SPAC11E3.05 SPNCRNA.1067 map1
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
152860535286181
252862215286562
352866095286821
452868775287290

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF12539 Pfam Monopolin complex, subunit Csm1/Pcs1 169 247 72.3 1

Sequence Feature

Term IDDescriptionSourceAll Genes
SO:0000288coiled-coilTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000288

Protein Properties

Ave. residue weight 116.55 Da
Charge -4.00
Isoelectric point 5.50
Molecular weight 30.42 kDa
Number of residues 261
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000070mitotic sister chromatid segregationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000070
IMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference
GO:0045144meiotic sister chromatid segregationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0045144
IMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year reference
GO:0051315attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0051315
GO:0051456attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0051456

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000775chromosome, centromeric regionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000775
GO:0000778condensed nuclear chromosome kinetochoreISS SGD:S000000682GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000778
GO:0005634nucleusIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
GO:0005730nucleolusISS SGD:S000000682GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005730
GO:0005829cytosolIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005829
GO:0033551monopolin complexIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0033551

Warning

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DescriptionSourceAll Genes
gene structure updated Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)] Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Species Distribution

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DescriptionSourceAll Genes
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
conserved in Fungi onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000056
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
hmt1ATP-binding cassette-type vacuolar membrane transporter Hmt1 Synthetic Lethality
Synthetic Growth Defect

Physical Interactions from BioGRID

Gene Feature Evidence Source
cnp3CENP-C Two-hybrid
mde4monopolin-like complex subunit Mde4 Affinity Capture-MS
Reconstituted Complex

External References

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Database Identifier Description
NBRP SPAC11E3.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC11E3.03 Retrieval of eukaryotic orthologs
BioGrid SPAC11E3.03 BioGRID Interaction Datasets
Bähler Lab SPAC11E3.03 Cell Cycle Expression Profile
Bähler Lab SPAC11E3.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC11E3.03 Pheromone response/mating expression profiles
Bähler Lab SPAC11E3.03 Environmental stress expression profiles
Bähler Lab SPAC11E3.03 Bähler Lab Transcriptome Viewer
Cyclebase SPAC11E3.03 Cell Cycle Data
Entrez Gene SPAC11E3.03 Link to Entrez Gene
SPD / RIKEN12/12F02Orfeome Localization Data
UniProtKB/SwissProtO13684Chromosome segregation protein pcs1
ArrayExpressO13684Link to ArrayExpress
RefSeq PeptideNP_001018298chromosome segregation protein Pcs1 (predicted)
RefSeq mRNANM_001020359972h- chromosome segregation protein Pcs1 (predicted) (pcs1), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAD88639ENA Protein Mapping
UniParcUPI000228F395UniProt Archive

Literature for pcs1

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Search: UK PMC or PubMed