rpl3002 (SPAC1250.05)


Gene Standard Namerpl3002 Characterisation Statusbiological_role_inferred
Systematic IDSPAC1250.05 Feature Typeprotein coding
Synonymsrpl30, rpl30-2 Name Description
Product60S ribosomal protein L30 (predicted) Product Size117aa, 12.24 kDa
Genomic Location Chromosome I, 5095925-5095073 (853nt); CDS:5095810-5095211 (600nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000002998GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationISOSGD:S000002998GO_REF:0000024473
GO:0006364rRNA processingISOSGD:S000002998GO_REF:0000024193
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722315
GO:0022625cytosolic large ribosomal subunitISOSGD:S000002998GO_REF:000002483
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpl3002ΔNullPECO:0000005, PECO:0000137PMID:236978063759
Microscopyrpl3002ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002938normal mRNA level during vegetative growth9
affecting rpl3002Transcript expression level evidencerpl3002Δi (91-337)Not specifiedPMID:24081329
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopyrpl3002ΔNullPECO:0000005, PECO:0000137PMID:23697806
Target Of
OntologyRelationshipGeneProductReference
FYPO affected by mutation in mtl1 TRAMP complex ATP-dependent RNA helicase (predicted) PMID:24210919
FYPO affected by mutation in nab2 poly(A) binding protein Nab2 (predicted) PMID:24081329
FYPO affected by mutation in pab2 poly(A) binding protein Pab2 PMID:24081329
FYPO affected by mutation in prp1 U4/U6 x U5 tri-snRNP complex subunit Prp1 PMID:24081329
FYPO affected by mutation in prp2 U2AF large subunit (U2AF-59) PMID:24081329
FYPO affected by mutation in red1 RNA elimination defective protein Red1 PMID:24210919
FYPO affected by mutation in rpl3001 60S ribosomal protein L30 (predicted) PMID:24081329
FYPO affected by mutation in rrp6 exosome 3'-5' exoribonuclease subunit Rrp6 (predicted) PMID:24081329
FYPO affected by mutation in rrp6 exosome 3'-5' exoribonuclease subunit Rrp6 (predicted) PMID:24210919
GO regulated by nab2 poly(A) binding protein Nab2 (predicted) PMID:24081329
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
150959255095548
250953015095073

UTRs

Region Coordinates Reference
five_prime_UTR5095925..5095811PMID:21511999
three_prime_UTR5095210..5095073PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01248 Pfam IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 23 115 7
PS00709 Prosite Patterns IPR022991 Ribosomal protein L30e, conserved site 34 58 2
PS00993 Prosite Patterns IPR022991 Ribosomal protein L30e, conserved site 90 110 2
PTHR11449 HMMPANTHER IPR000231 Ribosomal protein L30e 11 116 2
3.30.1330.30 Gene3D 17 115 10
SSF55315 SuperFamily 50S ribosomal protein L30e-like 23 116 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 104.64 Da
Charge 11.00
Isoelectric point 10.40
Molecular weight 12.24 kDa
Number of residues 117
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residueNASPMID:195477441922
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
90255during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
94865during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
96012during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
93967during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
87093.72during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
91816during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
13649.15during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
19during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
3.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4600
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3425
conserved in vertebrates3400
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
nab2poly(A) binding protein Nab2 (predicted) Affinity Capture-RNAPMID:24081329
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC1250.05 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1250.05 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1250.05 BioGRID Interaction Datasets
Expression Viewer SPAC1250.05 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1250.05 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1250.05 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1250.05 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1250.05 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1250.05 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1250.05 Cell Cycle Data
GEO SPAC1250.05 GEO profiles
PInt SPAC1250.05 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1250.05 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1250.05 Fission yeast phenotypic data & analysis
SPD / RIKEN31/31F05Orfeome Localization Data
UniProtKB/SwissProtQ9UTP060S ribosomal protein L30-2
ModBaseQ9UTP0Database of comparative protein structure models
STRINGQ9UTP0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59485760S ribosomal protein L30
RefSeq mRNANM_001020286972h- 60S ribosomal protein L30 (rpl3002), mRNA
European Nucleotide ArchiveCAB54828.1ENA Protein Mapping
UniParcUPI0000132F9CUniProt Archive

Literature for rpl3002

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014