taf9 (SPAC12G12.05c)


Gene Standard Nametaf9 Characterisation Statuspublished
Systematic IDSPAC12G12.05c Feature Typeprotein coding
Synonyms Name Description
ProductSAGA complex/ transcription initiation factor Taf9 Product Size163aa, 18.45 kDa
Genomic Location Chromosome I, 338286-339763 (1478nt); CDS:338392-338883 (492nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
chromatin remodeling160
Annotation ExtensionEvidenceWith/FromReference
histone acetylation47
Annotation ExtensionEvidenceWith/FromReference
regulation of transcription from RNA polymerase II promoter291
Annotation ExtensionEvidenceWith/FromReference
transcription initiation from RNA polymerase II promoter36
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2315
Annotation ExtensionEvidenceWith/FromReference
nuclear chromatin283
Annotation ExtensionEvidenceWith/FromReference
nucleus2740
Annotation ExtensionEvidenceWith/FromReference
SAGA complex19
Annotation ExtensionEvidenceWith/FromReference
transcription factor TFIID complex16
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopytaf9ΔNullPECO:0000005, PECO:0000137PMID:236978061338
Microscopytaf9ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002148inviable after spore germination, multiple cell divisions, abnormal morphology187
penetrance FYPO_EXT:0000001Microscopytaf9ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0000049inviable cellCell growth assaytaf9ΔNullPMID:216429551449
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1338286339763

UTRs

Region Coordinates Reference
five_prime_UTR338286..338391PMID:21511999
three_prime_UTR338884..339763PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02291 Pfam IPR003162 Transcription initiation factor TAFII31 4 132 1
PTHR12075 HMMPANTHER IPR003162 Transcription initiation factor TAFII31 1 152 1
1.10.20.10 Gene3D IPR009072 Histone-fold 14 82 27
SSF47113 SuperFamily IPR009072 Histone-fold 14 81 26

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000297histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Protein Properties

Ave. residue weight 113.18 Da
Charge -2.00
Isoelectric point 5.65
Molecular weight 18.45 kDa
Number of residues 163
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS146PMID:217125471670
present during mitotic M phase
present during mitotic M phaseexperimental evidenceS162PMID:21712547
present during mitotic M phaseexperimental evidenceS3PMID:21712547
experimental evidenceS162PMID:24763107
present during mitotic M phaseexperimental evidenceS2PMID:21712547
experimental evidenceS2PMID:24763107
experimental evidenceS3PMID:24763107
MOD:00696phosphorylated residueNASPMID:195477441922
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6872.75during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
9417.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6.4during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
1.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
tra1SAGA complex phosphatidylinositol pseudokinase Tra1 Affinity Capture-MSPMID:21642955
hfi1SAGA complex subunit Hfi1 Affinity Capture-MSPMID:19056896
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
ada1adenosine deaminase Ada1 Affinity Capture-MSPMID:21642955
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
spt7SAGA complex bromodomain subunit Spt7 Affinity Capture-MSPMID:19056896
External References
Database Identifier Description
NBRP SPAC12G12.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC12G12.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC12G12.05c BioGRID Interaction Datasets
Expression Viewer SPAC12G12.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC12G12.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC12G12.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC12G12.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC12G12.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC12G12.05c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC12G12.05c Cell Cycle Data
GEO SPAC12G12.05c GEO profiles
PInt SPAC12G12.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC12G12.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC12G12.05c Fission yeast phenotypic data & analysis
SPD / RIKEN04/04F10Orfeome Localization Data
UniProtKB/SwissProtQ09869Transcription initiation factor TFIID subunit 9
ModBaseQ09869Database of comparative protein structure models
STRINGQ09869Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592893SAGA complex/ transcription initiation factor Taf9
RefSeq mRNANM_001018293972h- SAGA complex/ transcription initiation factor Taf9 (taf9), mRNA
European Nucleotide ArchiveCAA91500.1ENA Protein Mapping
UniParcUPI000013A097UniProt Archive

Literature for taf9

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014