taf9 (SPAC12G12.05c)

Gene Standard Nametaf9 Characterisation Statuspublished
Systematic IDSPAC12G12.05c Feature Typeprotein coding
Synonyms Name Description
ProductSAGA complex/ transcription initiation factor Taf9 Product Size163aa, 18.45 kDa
Genomic Location Chromosome I, 338286-339763 (1478nt); CDS:338392-338883 (492nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000991core RNA polymerase II binding transcription factor activityISOSGD:S000004849GO_REF:000002433
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006338chromatin remodelingICGO:0005669GO_REF:0000001160
GO:0016573histone acetylationISOSGD:S000004849GO_REF:000002447
GO:0006357regulation of transcription from RNA polymerase II promoterISOSGD:S000004849GO_REF:0000024291
GO:0006367transcription initiation from RNA polymerase II promoterISOSGD:S000004849GO_REF:000002436
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000124SAGA complexIDAPMID:1905689619
GO:0000790nuclear chromatinICGO:0000124GO_REF:0000001283
GO:0005669transcription factor TFIID complexISOSGD:S000004849GO_REF:000002416
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopytaf9ΔNullPECO:0000005, PECO:0000137PMID:236978061338

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002148inviable after spore germination, multiple cell divisions, abnormal morphology187
penetrance FYPO_EXT:0000001Microscopytaf9ΔNullPECO:0000005, PECO:0000137PMID:23697806
FYPO:0000049inviable cellCell growth assaytaf9ΔNullPMID:216429551449
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02291 Pfam IPR003162 Transcription initiation factor TAFII31 4 132 1
PTHR12075 HMMPANTHER IPR003162 Transcription initiation factor TAFII31 1 152 1 Gene3D IPR009072 Histone-fold 14 82 27
SSF47113 SuperFamily IPR009072 Histone-fold 14 81 26

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000297histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Protein Properties

Ave. residue weight 113.18 Da
Charge -2.00
Isoelectric point 5.65
Molecular weight 18.45 kDa
Number of residues 163

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS146PMID:217125471670
present during mitotic M phase
present during mitotic M phaseexperimental evidenceS162PMID:21712547
present during mitotic M phaseexperimental evidenceS3PMID:21712547
experimental evidenceS162PMID:24763107
present during mitotic M phaseexperimental evidenceS2PMID:21712547
experimental evidenceS2PMID:24763107
experimental evidenceS3PMID:24763107
MOD:00696phosphorylated residueNASPMID:195477441922
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6872.75during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
9417.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6.4during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
1.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
tra1SAGA complex phosphatidylinositol pseudokinase Tra1 Affinity Capture-MSPMID:21642955
hfi1SAGA complex subunit Hfi1 Affinity Capture-MSPMID:19056896
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
ada1adenosine deaminase Ada1 Affinity Capture-MSPMID:21642955
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
spt7SAGA complex bromodomain subunit Spt7 Affinity Capture-MSPMID:19056896
External References
Database Identifier Description
NBRP SPAC12G12.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC12G12.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC12G12.05c BioGRID Interaction Datasets
Expression Viewer SPAC12G12.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC12G12.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC12G12.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC12G12.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC12G12.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC12G12.05c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC12G12.05c Cell Cycle Data
GEO SPAC12G12.05c GEO profiles
PInt SPAC12G12.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC12G12.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC12G12.05c Fission yeast phenotypic data & analysis
SPD / RIKEN04/04F10Orfeome Localization Data
UniProtKB/SwissProtQ09869Transcription initiation factor TFIID subunit 9
ModBaseQ09869Database of comparative protein structure models
STRINGQ09869Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592893SAGA complex/ transcription initiation factor Taf9
RefSeq mRNANM_001018293972h- SAGA complex/ transcription initiation factor Taf9 (taf9), mRNA
European Nucleotide ArchiveCAA91500.1ENA Protein Mapping
UniParcUPI000013A097UniProt Archive

Literature for taf9

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014