taf9 (SPAC12G12.05c)

Gene Standard Nametaf9 Characterisation Statuspublished
Systematic IDSPAC12G12.05c Feature Typeprotein coding
Synonyms Name Description
ProductSAGA complex/ transcription initiation factor Taf9 Product Size163aa, 18.45 kDa
Genomic Location Chromosome I, 338286-339763 (1478nt); CDS:338392-338883 (492nt)

Ensembl Gene Location
GO Molecular Function
GO Biological Process
Term NameCount
chromatin remodeling159
Annotation ExtensionEvidenceWith/FromReference
histone acetylation46
Annotation ExtensionEvidenceWith/FromReference
transcription initiation from RNA polymerase II promoter37
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
nuclear chromatin364
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
SAGA complex19
Annotation ExtensionEvidenceWith/FromReference
transcription factor TFIID complex16
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationtaf9Δ1468

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, multiple cell divisions, abnormal morphologytaf9Δ205
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR338286..338391PMID:21511999
3' UTR338884..339763PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02291 Pfam IPR003162 Transcription initiation factor TAFII31 13 131 1
PTHR12595:SF6 HMMPANTHER 1 154 1
PTHR12595 HMMPANTHER 1 154 2 Gene3D IPR009072 Histone-fold 14 82 27
SSF47113 SuperFamily IPR009072 Histone-fold 14 81 26

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000297histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Protein Properties

Ave. residue weight 113.18 Da
Charge -2.00
Codon Adaptation Index 0.36
Isoelectric point 5.65
Molecular weight 18.45 kDa
Number of residues 163

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 2293
present during mitotic M phaseS162
present during mitotic M phaseS146
present during mitotic M phaseS3
present during mitotic M phaseS2
S2, S3, S159, S162
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S162 PMID:21712547
present during mitotic M phase experimental evidence S146 PMID:21712547
present during mitotic M phase experimental evidence S3 PMID:21712547
present during mitotic M phase experimental evidence S2 PMID:21712547
experimental evidence S3 PMID:24763107
IDA S162 PMID:25720772
experimental evidence S162 PMID:24763107
experimental evidence S2 PMID:24763107
IDA S159 PMID:25720772
phosphorylated residue 2515
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
sumoylated lysine 174
Annotation ExtensionEvidenceResidueReference
IDA PMID:26404184
O-phosphorylated residueS159,S162 2461
Annotation ExtensionEvidenceResidueReference
IDA S159,S162 PMID:25720772
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for taf9 (SPAC12G12.05c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6872.75during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
9417.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
6.4during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
1.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC12G12.05c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byada1adenosine deaminase Ada1 Affinity Capture-MSPMID:21642955
affinity captured bycbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
affinity captured bytra1SAGA complex phosphatidylinositol pseudokinase Tra1 Affinity Capture-MSPMID:21642955
affinity captured bybdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
affinity captured byspt7SAGA complex bromodomain subunit Spt7 Affinity Capture-MSPMID:19056896
affinity captured byhfi1SAGA complex subunit Hfi1/Ada1 Affinity Capture-MSPMID:19056896
External References
Database Identifier Description
NBRP SPAC12G12.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC12G12.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC12G12.05c BioGRID Interaction Datasets
Expression Viewer SPAC12G12.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC12G12.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC12G12.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC12G12.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC12G12.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC12G12.05c Transcriptome Viewer (Bähler Lab)
GEO SPAC12G12.05c GEO profiles
PInt SPAC12G12.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC12G12.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC12G12.05c Fission yeast phenotypic data & analysis
Cyclebase SPAC12G12.05c.1 Cell Cycle Data
SPD / RIKEN04/04F10Orfeome Localization Data
UniProtKB/SwissProtQ09869Transcription initiation factor TFIID subunit 9
ModBaseQ09869Database of comparative protein structure models
STRINGQ09869Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592893SAGA complex/ transcription initiation factor Taf9
RefSeq mRNANM_001018293972h- SAGA complex/ transcription initiation factor Taf9 (taf9), mRNA
European Nucleotide ArchiveCAA91500.1ENA Protein Mapping
UniParcUPI000013A097UniProt Archive

Literature for taf9

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017