tht1 (SPAC13C5.03)

Gene Standard Nametht1 ChromosomeI
Systematic IDSPAC13C5.03 Gene Start427350
Synonyms Gene End430121
Productnuclear membrane protein involved in karyogamy Tht1 Gene Length2772
Feature Typeprotein coding CDS Start427583
Name Description CDS End429318
Characterisation Statuspublished CDS Length1736

Ensembl Gene Location
  1. gef2
  2. SPAC13C5.01c
  3. dre4
  4. tht1
  5. SPNCRNA.644
  6. SPAC13C5.04
  7. SPNCRNA.645
  8. snR40
  9. SPAC13C5.05c
  10. mug121
  11. prl5
  12. SPNCRNA.646
  13. mre11
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopytht1delta (deletion)deletionPMID:20473289
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000742karyogamy involved in conjugation with cellular fusionIMPPMID:9442101
GO:0048288nuclear membrane fusion involved in karyogamy
requiredIMPPMID:9442101
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0005783endoplasmic reticulumIDAPMID:16823372
GO:0005789endoplasmic reticulum membraneIEASL-0097GO_REF:0000039
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
GO:0031965nuclear membraneIDAPMID:9442101
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1427350427943
2427986428590
3428653430121

References

Region Start End Reference
five_prime_UTR427350427582PMID:21511999
three_prime_UTR429319430121PMID:21511999
three_prime_UTR429319430121PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04163 IPR007292 Pfam Nuclear fusion protein, KAR5 1 510 1
TMhelix TMHMM 401 423 955
TMhelix TMHMM 372 394 955
TMhelix TMHMM 438 460 955
Coil ncoils Rabaptin coiled-coil domain 307 328 974

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0000418signal_peptide
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 115.87 Da
Charge -1.50
Isoelectric point 6.33
Molecular weight 62.92 kDa
Number of residues 543
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.059PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.16PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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External References
Database Identifier Description
NBRP SPAC13C5.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13C5.03 Retrieval of eukaryotic orthologs
BioGrid SPAC13C5.03 BioGRID Interaction Datasets
Bähler Lab SPAC13C5.03 Cell Cycle Expression Profile
Bähler Lab SPAC13C5.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC13C5.03 Pheromone response/mating expression profiles
Bähler Lab SPAC13C5.03 Environmental stress expression profiles
Bähler Lab SPAC13C5.03 Bähler Lab Transcriptome Viewer
Cyclebase SPAC13C5.03 Cell Cycle Data
PInt SPAC13C5.03 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC13C5.03 Entrez Gene
SPD / RIKEN35/35G11Orfeome Localization Data
WikiGene2542365nuclear membrane protein involved in karyogamy Tht1
Uniprot_genenameTHT1
EntrezGene2542365nuclear membrane protein involved in karyogamy Tht1
UniProtKB/SwissProtQ09684Nuclear fusion protein tht1
ModBaseQ09684Database of comparative protein structure models
Pfam Protein DomainsQ09684Pfam Domain Arrangement
RefSeq PeptideNP_592931nuclear membrane protein involved in karyogamy Tht1
RefSeq mRNANM_001018332972h- nuclear membrane protein involved in karyogamy Tht1 (tht1), mRNA
European Nucleotide ArchiveBAA13334ENA Protein Mapping
European Nucleotide ArchiveCAA90454ENA Protein Mapping
UniParcUPI0000162016UniProt Archive

Literature for tht1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013