ptr6 (SPAC13F5.02c)


Gene Standard Nameptr6 Characterisation Statuspublished
Systematic IDSPAC13F5.02c Feature Typeprotein coding
Synonymstaf7 Name Description
Producttranscription factor TFIID complex subunit Taf7 Product Size393aa, 45.00 kDa
Genomic Location Chromosome I, 2173796-2172410 (1387nt); CDS:2173752-2172530 (1223nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
core RNA polymerase II binding transcription factor activity33
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
nucleus2695
Annotation ExtensionEvidenceWith/FromReference
transcription factor TFIID complex16
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationptr6ΔNull1435

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination with normal, unseptated germ tube morphologyptr6ΔNull237
inviable sporeptr6ΔNull470
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2173796..2173425, 2173383..2172410
mRNA2173796..2172410
5' UTR2173796..2173753PMID:21511999
CDS2173752..2173425, 2173383..2172530
3' UTR2172529..2172410PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04658 Pfam IPR006751 TAFII55 protein, conserved region 72 223 1
PTHR12228:SF0 HMMPANTHER 1 388 1
PTHR12228 HMMPANTHER 1 388 1
Coil ncoils Rabaptin coiled-coil domain 302 340 968
Coil ncoils Rabaptin coiled-coil domain 204 225 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.50 Da
Charge -21.50
Isoelectric point 4.57
Molecular weight 45.00 kDa
Number of residues 393
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during cellular response to thiabendazoleS310
present during cellular response to thiabendazoleS308
present during mitotic M phaseS16
present during mitotic M phaseS18
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S16 PMID:21712547
present during mitotic M phase experimental evidence S18 PMID:21712547
present during cellular response to thiabendazole IDA S308 PMID:18257517
present during cellular response to thiabendazole IDA S310 PMID:18257517
O-phospho-L-threonine 698
present during mitotic M phaseT20
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T20 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1188.2during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
6299.86during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.3during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bybdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
affinity captured bytaf5SAGA complex subunit/TATA-binding protein associated factor/transcription factor TFIID complex subunit Taf5 Affinity Capture-WesternPMID:11972332
affinity captured bytaf5SAGA complex subunit/TATA-binding protein associated factor/transcription factor TFIID complex subunit Taf5 Affinity Capture-WesternPMID:11279037
affinity captured bytaf73transcription factor TFIID complex subunit Taf5-like Affinity Capture-WesternPMID:11972332
affinity captured bytaf73transcription factor TFIID complex subunit Taf5-like Affinity Capture-WesternPMID:11279037
External References
Database Identifier Description
NBRP SPAC13F5.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13F5.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC13F5.02c BioGRID Interaction Datasets
Expression Viewer SPAC13F5.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC13F5.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC13F5.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC13F5.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC13F5.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC13F5.02c Transcriptome Viewer (Bähler Lab)
GEO SPAC13F5.02c GEO profiles
PInt SPAC13F5.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC13F5.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC13F5.02c Fission yeast phenotypic data & analysis
Cyclebase SPAC13F5.02c.1 Cell Cycle Data
SPD / RIKEN22/22B07Orfeome Localization Data
UniProtKB/SwissProtO13701Transcription initiation factor TFIID subunit 7
ModBaseO13701Database of comparative protein structure models
STRINGO13701Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593650transcription factor TFIID complex subunit Taf7
RefSeq mRNANM_001019082972h- transcription factor TFIID complex subunit Taf7 (ptr6), mRNA
European Nucleotide ArchiveBAA32487.1ENA Protein Mapping
European Nucleotide ArchiveCAB11765.1ENA Protein Mapping
UniParcUPI00001367E9UniProt Archive

Literature for ptr6

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015