ptr6 (SPAC13F5.02c)


Gene Standard Nameptr6 Characterisation Statuspublished
Systematic IDSPAC13F5.02c Feature Typeprotein coding
Synonymstaf7 Name Description
Producttranscription factor TFIID complex subunit Taf7 Product Size393aa, 45.00 kDa
Genomic Location Chromosome I, 2173796-2172410 (1387nt); CDS:2173752-2172530 (1223nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
transcription factor activity, core RNA polymerase II binding33
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
nucleus2692
Annotation ExtensionEvidenceWith/FromReference
transcription factor TFIID complex16
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationptr6Δ1453

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination with normal, unseptated germ tube morphologyptr6Δ237
inviable sporeptr6Δ476
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2173796..2173425, 2173383..2172410
Intron2173424..2173384
5' UTR2173796..2173753PMID:21511999
3' UTR2172529..2172410PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04658 Pfam IPR006751 TAFII55 protein, conserved region 72 222 1
PTHR12228:SF0 HMMPANTHER 10 393 1
PTHR12228 HMMPANTHER 10 393 1
Coil ncoils Predicted coiled-coil protein (DUF2205) 302 339 1057
Coil ncoils Predicted coiled-coil protein (DUF2205) 204 224 1057

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.50 Da
Charge -21.50
Codon Adaptation Index 0.44
Isoelectric point 4.57
Molecular weight 45.00 kDa
Number of residues 393
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1676
present during mitotic M phaseS18
present during cellular response to thiabendazoleS310
present during cellular response to thiabendazoleS308
present during mitotic M phaseS16
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S18 PMID:21712547
present during cellular response to thiabendazole IDA S310 PMID:18257517
present during cellular response to thiabendazole IDA S308 PMID:18257517
present during mitotic M phase experimental evidence S16 PMID:21712547
O-phospho-L-threonine 700
present during mitotic M phaseT20
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T20 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for ptr6 (SPAC13F5.02c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1188.2during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
6299.86during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.3during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
1.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4605
conserved in eukaryotes4515
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC13F5.02c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bybdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
affinity captured bytaf73transcription factor TFIID complex subunit Taf5-like Affinity Capture-WesternPMID:11279037
affinity captured bypir2zf-C2H2 type zinc finger protein, implicated in RNAi (predicted) Affinity Capture-MSPMID:24713849
affinity captured bytaf5SAGA complex subunit/TATA-binding protein associated factor/transcription factor TFIID complex subunit Taf5 Affinity Capture-WesternPMID:11279037
binds activation domain construct withrng3UCS-domain protein Rng3 Two-hybridPMID:26771498
binds activation domain construct withSPCC645.12cSchizosaccharomyces specific protein Two-hybridPMID:26771498
External References
Database Identifier Description
NBRP SPAC13F5.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13F5.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC13F5.02c BioGRID Interaction Datasets
Expression Viewer SPAC13F5.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC13F5.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC13F5.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC13F5.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC13F5.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC13F5.02c Transcriptome Viewer (Bähler Lab)
GEO SPAC13F5.02c GEO profiles
PInt SPAC13F5.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC13F5.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC13F5.02c Fission yeast phenotypic data & analysis
Cyclebase SPAC13F5.02c.1 Cell Cycle Data
SPD / RIKEN22/22B07Orfeome Localization Data
UniProtKB/SwissProtO13701Transcription initiation factor TFIID subunit 7
ModBaseO13701Database of comparative protein structure models
STRINGO13701Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593650transcription factor TFIID complex subunit Taf7
RefSeq mRNANM_001019082972h- transcription factor TFIID complex subunit Taf7 (ptr6), mRNA

Literature for ptr6

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016