rps601 (SPAC13G6.07c)


Gene Standard Namerps601 Characterisation Statuspublished
Systematic IDSPAC13G6.07c Feature Typeprotein coding
Synonymsrps6-1 Name Description
Product40S ribosomal protein S6 Product Size239aa, 27.50 kDa
Genomic Location Chromosome I, 187683-186314 (1370nt); CDS:187563-186844 (720nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000006011GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0042254ribosome biogenesisISOSGD:S000006011GO_REF:0000024325
GO:0006412translationISOSGD:S000006011GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722316
GO:0022627cytosolic small ribosomal subunitISOSGD:S000006011GO_REF:000002464
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrps601ΔNullPMID:204732893730
Microscopyrps601ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001122elongated vegetative cellMicroscopyrps601+ (wild type)OverexpressionPMID:12237855657
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrps601ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1187683186314

UTRs

Region Coordinates Reference
five_prime_UTR187683..187564PMID:21511999
three_prime_UTR186843..186314PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01092 Pfam IPR001377 Ribosomal protein S6e 1 126 2
PS00578 Prosite Patterns IPR018282 Ribosomal protein S6e, conserved site 52 63 2
PTHR11502 HMMPANTHER IPR001377 Ribosomal protein S6e 2 239 2
PIRSF002129 PIRSF IPR014401 Ribosomal protein S6, eukaryotic 1 239 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.06 Da
Charge 34.00
Isoelectric point 11.49
Molecular weight 27.50 kDa
Number of residues 239
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS236PMID:247631071669
S235PMID:24763107
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
482619during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
497991during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
470213during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
518690during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
1159.5during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
466852during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
5613.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
68during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
6.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3393
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rps60240S ribosomal protein S6 (predicted) Phenotypic EnhancementPMID:20144990
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
External References
Database Identifier Description
NBRP SPAC13G6.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13G6.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC13G6.07c BioGRID Interaction Datasets
Expression Viewer SPAC13G6.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC13G6.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC13G6.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC13G6.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC13G6.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC13G6.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC13G6.07c Cell Cycle Data
GEO SPAC13G6.07c GEO profiles
PInt SPAC13G6.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC13G6.07c Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN08/08E07Orfeome Localization Data
WikiGene254287040S ribosomal protein S6
EntrezGene254287040S ribosomal protein S6
UniProtKB/SwissProtP0575240S ribosomal protein S6-A
ModBaseP05752Database of comparative protein structure models
STRINGP05752Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59283340S ribosomal protein S6
RefSeq mRNANM_001018234972h- 40S ribosomal protein S6 (rps601), mRNA
European Nucleotide ArchiveAAA35338ENA Protein Mapping
European Nucleotide ArchiveAAA35338.1ENA Protein Mapping
European Nucleotide ArchiveCAA91100ENA Protein Mapping
European Nucleotide ArchiveCAA91100.1ENA Protein Mapping
ReactomeREACT_188294
ReactomeREACT_188542
ReactomeREACT_188560
ReactomeREACT_206850
ReactomeREACT_210923
ReactomeREACT_215930
ReactomeREACT_226552
UniParcUPI0000135087UniProt Archive

Literature for rps601

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014