rps601 (SPAC13G6.07c)


Gene Standard Namerps601 Characterisation Statuspublished
Systematic IDSPAC13G6.07c Feature Typeprotein coding
Synonymsrps6-1 Name Description
Product40S ribosomal protein S6 Product Size239aa, 27.50 kDa
Genomic Location Chromosome I, 187683-186314 (1370nt); CDS:187563-186844 (720nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation468
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis338
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationrps601ΔNull3783

Cell Phenotype

Term NameAlleleExpressionCount
elongated vegetative cellrps601+ (wild type)Overexpression705
viable vegetative cell with normal cell morphologyrps601ΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1187683186314

UTRs

Region Coordinates Reference
five_prime_UTR187683..187564PMID:21511999
three_prime_UTR186843..186314PMID:21511999
exon187563..186844
mRNA187683..186314
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01092 Pfam IPR001377 Ribosomal protein S6e 1 126 2
PS00578 Prosite Patterns IPR018282 Ribosomal protein S6e, conserved site 52 63 2
PTHR11502 HMMPANTHER IPR001377 Ribosomal protein S6e 2 239 2
PTHR11502:SF6 HMMPANTHER 2 239 2
PIRSF002129 PIRSF IPR014401 Ribosomal protein S6, eukaryotic 1 239 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.06 Da
Charge 34.00
Isoelectric point 11.49
Molecular weight 27.50 kDa
Number of residues 239
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS235, S236 1670
Annotation ExtensionEvidenceResidueReference
experimental evidence S235 PMID:24763107
experimental evidence S236 PMID:24763107
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
482619during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
497991during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
470213during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
518690during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
466852during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
1159.5during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
5613.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
68during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
6.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
affinity captured bynak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
phenotype enhanced byrps60240S ribosomal protein S6 (predicted) Phenotypic EnhancementPMID:20144990
External References
Database Identifier Description
NBRP SPAC13G6.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13G6.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC13G6.07c BioGRID Interaction Datasets
Expression Viewer SPAC13G6.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC13G6.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC13G6.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC13G6.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC13G6.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC13G6.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC13G6.07c Cell Cycle Data
GEO SPAC13G6.07c GEO profiles
PInt SPAC13G6.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC13G6.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC13G6.07c Fission yeast phenotypic data & analysis
SPD / RIKEN08/08E07Orfeome Localization Data
UniProtKB/SwissProtP0575240S ribosomal protein S6-A
ModBaseP05752Database of comparative protein structure models
STRINGP05752Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59283340S ribosomal protein S6
RefSeq mRNANM_001018234972h- 40S ribosomal protein S6 (rps601), mRNA
European Nucleotide ArchiveAAA35338.1ENA Protein Mapping
European Nucleotide ArchiveCAA91100.1ENA Protein Mapping
UniParcUPI0000135087UniProt Archive

Literature for rps601

Search: Europe PMC or PubMed

Release Version: PomBase:25_49 - 02 Feb 2015