rps601 (SPAC13G6.07c)

Gene Standard Namerps601 Characterisation Statuspublished
Systematic IDSPAC13G6.07c Feature Typeprotein coding
Synonymsrps6-1 Name Description
Product40S ribosomal protein S6 Product Size239aa, 27.50 kDa
Genomic Location Chromosome I, 187683-186314 (1370nt); CDS:187563-186844 (720nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation473
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis337
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrps601ΔNullPMID:204732893759
Microscopyrps601ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001122elongated vegetative cellMicroscopyrps601+ (wild type)OverexpressionPMID:12237855685
FYPO:0002177viable vegetative cell with normal cell morphology3089
penetrance FYPO_EXT:0000001Microscopyrps601ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01092 Pfam IPR001377 Ribosomal protein S6e 1 126 2
PS00578 Prosite Patterns IPR018282 Ribosomal protein S6e, conserved site 52 63 2
PTHR11502 HMMPANTHER IPR001377 Ribosomal protein S6e 1 239 2
PIRSF002129 PIRSF IPR014401 Ribosomal protein S6, eukaryotic 1 239 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.06 Da
Charge 34.00
Isoelectric point 11.49
Molecular weight 27.50 kDa
Number of residues 239

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS235PMID:247631071670
experimental evidenceS236PMID:24763107
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
482619during GO:0000080PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
497991during GO:0000084PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
470213during GO:0000085PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
518690during GO:0000087PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
466852during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
1159.5during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
5613.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
68during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
6.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in archaea237

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
nak1PAK-related kinase Nak1 Affinity Capture-MSPMID:23462181
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
rps60240S ribosomal protein S6 (predicted) Phenotypic EnhancementPMID:20144990
External References
Database Identifier Description
NBRP SPAC13G6.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC13G6.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC13G6.07c BioGRID Interaction Datasets
Expression Viewer SPAC13G6.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC13G6.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC13G6.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC13G6.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC13G6.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC13G6.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC13G6.07c Cell Cycle Data
GEO SPAC13G6.07c GEO profiles
PInt SPAC13G6.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC13G6.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC13G6.07c Fission yeast phenotypic data & analysis
SPD / RIKEN08/08E07Orfeome Localization Data
UniProtKB/SwissProtP0575240S ribosomal protein S6-A
ModBaseP05752Database of comparative protein structure models
STRINGP05752Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59283340S ribosomal protein S6
RefSeq mRNANM_001018234972h- 40S ribosomal protein S6 (rps601), mRNA
European Nucleotide ArchiveAAA35338.1ENA Protein Mapping
European Nucleotide ArchiveCAA91100.1ENA Protein Mapping
UniParcUPI0000135087UniProt Archive

Literature for rps601

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014