dsc2 (SPAC1486.02c)

Synonymsucp14 ChromosomeI
ProductUBA domain protein Ucp14 Gene Start3188100
Feature Typeprotein coding Gene End3186322
Name Description CDS Start3188067
Characterisation Statusconserved_unknown CDS End3186754

Ensembl Gene Location
rpl2301 oar2 nsk1 SPAC1486.01 > dsc2 < SPAC1486.03c prl14 alm1
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
131881003188049
231879413187811
331877223186322

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
TMHMM tmhmm Double transmembrane domain 15 33 0.99635 1312
TMHMM tmhmm Double transmembrane domain 55 74 0.98478 1312
TMHMM tmhmm Double transmembrane domain 92 112 0.99922 1312
TMHMM tmhmm Double transmembrane domain 131 150 0.95724 1312
TMHMM tmhmm Double transmembrane domain 167 190 0.83611 1312
SIGNALP_EUK Signalp 1 32 0 456


Protein Modifications

Term IDDescriptionSourceAll Genes
MOD:00696phosphorylated residue
Temporary processing gif - replaced by AJAX with count of genes annotated with the term MOD:00696

Sequence Feature

Term IDDescriptionSourceAll Genes
SO:0000065protein N-terminal signal sequenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000065
SO:0000073protein transmembrane helicesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000073

Protein Properties

Ave. residue weight 113.54 Da
Charge 5.00
Isoelectric point 8.38
Molecular weight 42.24 kDa
Number of residues 372
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Protein Family

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DescriptionSourceAll Genes
UBA domain proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000794

Species Distribution

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DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
srs2ATP-dependent DNA helicase, UvrD subfamily Negative Genetic
SPBC16A3.08cStm1 homolog (predicted) Negative Genetic
cip1RNA-binding protein Cip1 Negative Genetic
SPAC3H8.02sec14 cytosolic factor family phosphatidylinositol transporter (predicted) Negative Genetic
SPAC2H10.01transcription factor, zf-fungal binuclear cluster type (predicted) Negative Genetic
SPAC823.10cmitochondrial carrier with solute carrier repeats (predicted) Negative Genetic
ctu1cytosolic thiouridylase subunit Ctu1 Positive Genetic
but2But2 family protein But2 Positive Genetic
SPCC965.10transcription factor (predicted) Positive Genetic
fsv1SNARE Fsv1 Negative Genetic
pmm1phosphomannomutase Pmm1 Negative Genetic
fio1iron transport multicopper oxidase Fio1 Negative Genetic
tpp1trehalose-6-phosphate phosphatase Tpp1 Negative Genetic
tip1CLIP170 family protein Tip1 Negative Genetic
SPBC1198.08dipeptidase Dug1 (predicted) Negative Genetic
SPCC1183.11MS ion channel protein 1 (predicted) Negative Genetic
psh3ER chaperone SHR3 homologue Psh3 Positive Genetic
mus7DNA repair protein Mus7/Mms22 Negative Genetic
atp11F1-ATPase chaperone Atp11 (predicted) Negative Genetic
fep1iron-sensing transcription factor Fep1 Negative Genetic
SPCC622.04dubious Positive Genetic
nap1nucleosome assembly protein Nap1 Negative Genetic
SPBPB7E8.01sequence orphan Negative Genetic
vps25ESCRT II complex subunit Vps25 Negative Genetic
SPAC12B10.04tubulin-tyrosine ligase (predicted) Negative Genetic
ura3dihydroorotate dehydrogenase Ura3 Negative Genetic
apl1AP-2 adaptor complex subunit Apl1 (predicted) Positive Genetic
SPBC17A3.06phosphoprotein phosphatase (predicted) Negative Genetic
rpl120260S ribosomal protein L12.1/L12A Negative Genetic
SPAC1F12.03ccytochrome C oxidase transmembrane region Negative Genetic
gdh1NADP-specific glutamate dehydrogenase Gdh1 (predicted) Negative Genetic
pyp2tyrosine phosphatase Pyp2 Negative Genetic
SPAPB1A10.14F-box protein (predicted) Negative Genetic
rpl430260S ribosomal protein L37a (predicted) Negative Genetic
eng2endo-1,3-beta-glucanase Eng2 Positive Genetic
gld1mitochondrial glycerol dehydrogenase Gld1 Negative Genetic
SPAC977.17MIP water channel (predicted) Negative Genetic
swd3WD repeat protein Swd3 Negative Genetic
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative Genetic
SPAC17H9.08mitochondrial coenzyme A transporter (predicted) Positive Genetic
raf2Rik1-associated factor Raf2 Negative Genetic
qcr8ubiquinol-cytochrome-c reductase complex subunit 7 Negative Genetic
plc1phosphoinositide phospholipase C Plc1 Negative Genetic
ef1a-atranslation elongation factor EF-1 alpha Ef1a-a Negative Genetic
atp12F1-ATPase chaperone Atp12 (predicted) Negative Genetic
SPAC19A8.03phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative Genetic
rpl410160S ribosomal protein L41 Negative Genetic
ppr8mitochondrial PPR repeat protein Ppr8 Negative Genetic
rpl160160S ribosomal protein L13/L16 (predicted) Negative Genetic
SPAC212.06cDNA helicase in rearranged telomeric region, truncated Negative Genetic
SPBC1271.14glutamate N-acetyltransferase (predicted) Negative Genetic
SPBC21B10.08csequence orphan Negative Genetic
SPBC1348.01S. pombe specific DUF999 protein family 5 Negative Genetic
cmk1calcium/calmodulin-dependent protein kinase Cmk1 Negative Genetic
lag1sphingosine N-acyltransferase Lag1 Negative Genetic
iqw1WD repeat protein, Iqw1 Positive Genetic
SPCC1442.02central kinetochore associated family protein (predicted) Negative Genetic
SPAC27D7.02cGRIP domain protein (predicted) Negative Genetic
nse6Smc5-6 complex non-SMC subunit Nse6 Positive Genetic
SPAC4H3.12cdubious Negative Genetic
sib1ferrichrome synthetase Sib1 Positive Genetic
SPBC9B6.03zf-FYVE type zinc finger protein Negative Genetic
ura5orotate phosphoribosyltransferase Ura5 Positive Genetic
SPCC794.01cglucose-6-phosphate 1-dehydrogenase (predicted) Negative Genetic
bun107WD repeat protein, human WDR48 family Bun107 Negative Genetic
SPCC162.06cvacuolar sorting protein Vps60 (predicted) Negative Genetic
mrt4mRNA turnover and ribosome assembly protein Mrt4 (predicted) Negative Genetic
SPBC19G7.04HMG box protein Positive Genetic
meu29sequence orphan Negative Genetic
asl1cell wall protein Asl1, predicted O-glucosyl hydrolase Negative Genetic
cbp1CENP-B homolog Positive Genetic
arg3ornithine carbamoyltransferase Arg3 Negative Genetic
mug121sequence orphan Negative Genetic
SPCC550.07acetamidase (predicted) Positive Genetic
SPAC2F7.17mitochondrial peptide chain release factor (predicted) Positive Genetic
SPCC285.10cSPRY domain protein Negative Genetic
SPBC56F2.08cRNA-binding protein (predicted) Negative Genetic
pds5cohesin-associated protein Pds5 Positive Genetic
SPAC23H4.16csequence orphan Positive Genetic
SPAC750.08cNAD-dependent malic enzyme (predicted), partial Negative Genetic
SPBC582.10cATP-dependent DNA helicase Rhp16b (predicted) Negative Genetic
SPAC24B11.09mitochondrial protein, predicted, human BRP44 ortholog Negative Genetic
SPAC9G1.07sequence orphan Negative Genetic
erf2palmitoyltransferase Erf2 (predicted) Positive Genetic
est1telomerase regulator Est1 Negative Genetic
SPBC12C2.03cmethionine synthase reductase (predicted) Negative Genetic
SPBC21B10.07glycosyl hydrolase family 16 (predicted) Negative Genetic
akr1palmitoyltransferase Akr1 (predicted) Positive Genetic
SPAC3A12.06csodium/calcium exchanger (predicted) Negative Genetic
nep2NEDD8 protease Nep2 Negative Genetic
SPAC11D3.155-oxoprolinase (ATP-hydrolizing) (predicted) Negative Genetic
SPAC12B10.10sequence orphan Negative Genetic
SPBC27B12.11ctranscription factor (predicted) Negative Genetic
nup124nucleoporin Nup124 Negative Genetic
spn3septin Spn3 Negative Genetic
SPAC977.05cconserved fungal family Negative Genetic
chs2chitin synthase homolog Chs2 Positive Genetic
lsg1Lsk1 complex gamma subunit (predicted) Positive Genetic
SPBC1861.05carbohydrate kinase (predicted) Positive Genetic
SPBC13A2.04cPTR family peptide transporter (predicted) Negative Genetic
arg6acetylglutamate synthase Arg6 (predicted) Negative Genetic
SPAC10F6.04RCC domain protein Ats1 (predicted) Positive Genetic
SPBP35G2.14RNA-binding protein Negative Genetic
did4ESCRT III complex subunit Did4 Negative Genetic
bun62WD repeat protein, human WDR20 family, Bun62 Negative Genetic
SPCC1235.01sequence orphan Negative Genetic
trx2mitochondrial thioredoxin Trx2 Negative Genetic
egd2nascent polypeptide-associated complex alpha subunit Egd2 Positive Genetic
rtf1replication termination factor Rtf1 Negative Genetic
SPAC212.01cS. pombe specific DUF999 family protein 2 Negative Genetic
are2acyl-coA-sterol acyltransferase Are2 (predicted) Positive Genetic
gal1galactokinase Gal1 Negative Genetic
nop16ribosome biogenesis protein Nop16 (predicted) Negative Genetic
alg5dolichyl-phosphate beta-glucosyltransferase Alg5 (predicted) Negative Genetic
SPCC663.15cconserved fungal protein Negative Genetic
mak10NatC N-acetyltransferase complex subunit Mak10 (predicted) Positive Genetic
sst4sorting receptor for ubiquitinated membrane proteins, ESCRT 0 complex subunit Sst4 Negative Genetic
SPBC119.12Golgi matrix protein (predicted) Negative Genetic
sft2Golgi transport protein Sft2 (predicted) Negative Genetic
ubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Negative Genetic
SPAPB21F2.02Dopey family protein (predicted) Negative Genetic
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Negative Genetic
SPAC1039.02phosphoprotein phosphatase (predicted) Negative Genetic
ght6hexose transporter Ght6 Negative Genetic
mex67mRNA export receptor, Tap, nucleoporin Mex67 Negative Genetic
apt1adenine phosphoribosyltransferase (APRT) (predicted) Negative Genetic
SPAC4H3.04cUPF0103 family Negative Genetic
SPAC922.05cmembrane transporter (predicted) Negative Genetic
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative Genetic
SPAC26H5.07cseven transmembrane receptor protein (predicted) Negative Genetic
mac1membrane anchored protein Mac1 Negative Genetic
pnu1mitochondrial endodeoxyribonuclease Pnu1 Negative Genetic
mug170arrestin Negative Genetic
SPAC1399.04curacil phosphoribosyltransferase (predicted) Negative Genetic
scs7sphingosine hydroxylase Scs7 Positive Genetic
rpl100260S ribosomal protein L10 Negative Genetic
agn1glucan endo-1,3-alpha-glucosidase Agn1 Negative Genetic
SPCC1235.11mitochondrial protein, human BRP44L ortholog Negative Genetic
SPBC29A10.16ccytochrome b5 (predicted) Positive Genetic
sum2G2/M transition checkpoint protein Sum2 Negative Genetic
pit1serine/threonine protein kinase, meiotic Pit1 Negative Genetic
vps20ESCRT III complex subunit Vps20 Negative Genetic
srb11cyclin CycC, Srb mediator subunit Srb11 Negative Genetic
SPAC694.04cconserved eukaryotic protein Positive Genetic
SPBC23G7.13curea transporter (predicted) Negative Genetic
arg11N-acetyl-gamma-glutamyl-phosphate reductase/acetylglutamate kinase Negative Genetic
SPBC3E7.05chuman mitofilin ortholog (predicted) Positive Genetic
SPAC1687.21phosphoglycerate mutase family (predicted) Positive Genetic
sgf73SAGA complex subunit Sgf73 Negative Genetic
otu2ubiquitin specific cysteine protease, OTU family, Otu2 Negative Genetic
SPCC1795.10cSed5 Vesicle Protein Svp26 (predicted) Negative Genetic
SPAC750.01aldo/keto reductase family protein Negative Genetic
SPAC3C7.02cprotein kinase inhibitor associated with endocytosis (predicted) Negative Genetic
rik1silencing protein Rik1 Negative Genetic
oca2serine/threonine protein kinase Oca2 Negative Genetic
SPCC4B3.02cGolgi transport protein Got1 (predicted) Negative Genetic
SPCC126.09vacuolar membrane zinc transporter (predicted) Negative Genetic
ccr1NADPH-cytochrome p450 reductase Negative Genetic
cuf1nutritional copper sensing transcription factor Cuf1 Positive Genetic
mfr1fizzy-related protein Mfr1 Negative Genetic
mei2RNA-binding protein involved in meiosis Mei2 Negative Genetic
cnt5Centaurin 5 Negative Genetic
ssa1heat shock protein Ssa1 (predicted) Negative Genetic
SPAC1A6.03cphospholipase (predicted) Negative Genetic
SPCC550.11karyopherin (predicted) Negative Genetic
btf3nascent polypeptide-associated complex beta subunit Negative Genetic
rds1conserved fungal protein Negative Genetic
SPAC22H10.04protein phosphatase type 2A (predicted) Negative Genetic

Physical Interactions from BioGRID

Gene Feature Evidence Source
sre2membrane-tethered transcription factor (predicted) Affinity Capture-Western
dsc3conserved fungal protein Affinity Capture-Western
Co-purification
dsc1ubiquitin-protein ligase E3 (predicted) Co-purification
Affinity Capture-Western
Affinity Capture-MS
dsc4conserved fungal protein Co-purification
Affinity Capture-Western

External References

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Database Identifier Description
NBRP SPAC1486.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1486.02c Retrieval of eukaryotic orthologs
BioGrid SPAC1486.02c BioGRID Interaction Datasets
Bähler Lab SPAC1486.02c Cell Cycle Expression Profile
Bähler Lab SPAC1486.02c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1486.02c Pheromone response/mating expression profiles
Bähler Lab SPAC1486.02c Environmental stress expression profiles
Bähler Lab SPAC1486.02c Bähler Lab Transcriptome Viewer
Cyclebase SPAC1486.02c Cell Cycle Data
Entrez Gene SPAC1486.02c Link to Entrez Gene
SPD / RIKEN44/44C03Orfeome Localization Data
UniProtKB/SwissProtQ9UTK7UBA domain-containing protein 14
ArrayExpressQ9UTK7Link to ArrayExpress
RefSeq PeptideNP_594090UBA domain protein Ucp14
RefSeq mRNANM_001019514972h- UBA domain protein Ucp14 (ucp14), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAB62412ENA Protein Mapping
UniParcUPI0000069AB1UniProt Archive

Literature for dsc2

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Search: UK PMC or PubMed