agn1 (SPAC14C4.09)

Gene Standard Nameagn1 ChromosomeI
Systematic IDSPAC14C4.09 Gene Start5243953
Synonyms Gene End5245966
Productglucan endo-1,3-alpha-glucosidase Agn1 Gene Length2014
Feature Typeprotein coding CDS Start5244207
Name Description CDS End5245481
Characterisation Statuspublished CDS Length1275

Ensembl Gene Location
  1. man1
  2. SPAC14C4.06c
  3. SPAC14C4.07
  4. mug5
  5. agn1
  6. SPAC14C4.10c
  7. SPAC14C4.11
  8. laf1
  9. SPNCRNA.261
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000153clumped cellsno_name (unrecorded)unrecordedPMID:15194814
FYPO:0002060viable vegetative cell populationMicroscopyagn1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0051118glucan endo-1,3-alpha-glucosidase activityIDAPMID:15194814
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0009313oligosaccharide catabolic processICGO:0051118GO_REF:0000001
GO:0030995cell septum edging catabolic processIMPPMID:15194814
GO:0044247cellular polysaccharide catabolic processICGO:0051118GO_REF:0000001
GO:0046379extracellular polysaccharide metabolic processICGO:0009986, GO:0004339GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005576extracellular regionIDAPMID:15194814
GO:0009986cell surfaceIDAPMID:15194814
GO:0043188cell septum edgingIDAPMID:15194814
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
152439535245966

References

Region Start End Reference
three_prime_UTR52454825245966PMID:21511999
three_prime_UTR52454825245966PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03659 IPR005197 Pfam Glycoside hydrolase, family 71 23 403 2
PTHR10566:SF3 hmmpanther 220 351 2
PTHR10566 hmmpanther 220 351 6
SignalP-noTM signalp 1 20 212

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.79 Da
Charge -32.00
Isoelectric point 3.85
Molecular weight 46.97 kDa
Number of residues 424
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
promoter contains UAS PMID:16678171
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.38PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide5.8PMID:23101633
Subunit Composition
DescriptionQualifierReference
monomeric PMID:15194814
Warning
DescriptionQualifierReference
gene structure updated PMID:15194814
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi only
conserved in fungi
conserved in eukaryotes
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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
mug122PX/PXA domain protein Positive GeneticPMID:22681890
mid2medial ring protein Mid2 Phenotypic EnhancementPMID:16317047
SPAC18B11.03cN-acetyltransferase (predicted) Positive GeneticPMID:22681890
SPCC11E10.09calpha-amylase homolog (predicted) Positive GeneticPMID:22681890
mug170arrestin Positive GeneticPMID:22681890
SPCP1E11.10ankyrin repeat protein, unknown biological role Negative GeneticPMID:22681890
eng1endo-1,3-beta-glucanase Eng1 Phenotypic EnhancementPMID:16317047
Synthetic Growth DefectPMID:15689498
Phenotypic EnhancementPMID:15194814
adh4alcohol dehydrogenase Adh4 Positive GeneticPMID:22681890
sid2NDR kinase Sid2 Synthetic RescuePMID:16415366
ubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Positive GeneticPMID:22681890
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Positive GeneticPMID:22681890
SPCC1672.03cguanine deaminase (predicted) Positive GeneticPMID:22681890
rho4Rho family GTPase Rho4 Dosage LethalityPMID:16215171
Phenotypic Suppression
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
spn1septin Spn1 Co-localizationPMID:16079182
mid2medial ring protein Mid2 Co-localizationPMID:16079182
spn4septin Spn4 Co-localizationPMID:16079182
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External References
Database Identifier Description
NBRP SPAC14C4.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC14C4.09 Retrieval of eukaryotic orthologs
BioGrid SPAC14C4.09 BioGRID Interaction Datasets
Bähler Lab SPAC14C4.09 Cell Cycle Expression Profile
Bähler Lab SPAC14C4.09 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC14C4.09 Pheromone response/mating expression profiles
Bähler Lab SPAC14C4.09 Environmental stress expression profiles
Bähler Lab SPAC14C4.09 Bähler Lab Transcriptome Viewer
Cyclebase SPAC14C4.09 Cell Cycle Data
PInt SPAC14C4.09 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC14C4.09 Entrez Gene
WikiGene3361560glucan endo-1,3-alpha-glucosidase Agn1
Uniprot_genenameAGN1
EntrezGene3361560glucan endo-1,3-alpha-glucosidase Agn1
IntEnz3.2.1.59
SPD / RIKEN22/22B03Orfeome Localization Data
UniProtKB/SwissProtO13716Glucan endo-1,3-alpha-glucosidase agn1
ModBaseO13716Database of comparative protein structure models
Pfam Protein DomainsO13716Pfam Domain Arrangement
RefSeq PeptideNP_001018296glucan endo-1,3-alpha-glucosidase Agn1
RefSeq mRNANM_001020346972h- glucan endo-1,3-alpha-glucosidase Agn1 (agn1), mRNA
European Nucleotide ArchiveAAT84064ENA Protein Mapping
European Nucleotide ArchiveBAA87132ENA Protein Mapping
UniParcUPI00003B5C29UniProt Archive

Literature for agn1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013