SPAC1527.03


Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC1527.03 Feature Typeprotein coding
Synonyms Name Description
ProductRNA-binding protein (predicted) Product Size475aa, 53.23 kDa
Genomic Location Chromosome I, 4384450-4386950 (2501nt); CDS:4384659-4386086 (1428nt)

Ensembl Gene Location
  1. mok11
  2. sft2
  3. SPAC1527.03
  4. sec72
  5. SPAC30.02c
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003723RNA bindingISOSGD:S000000542GO_REF:0000024627
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0006412translationISOSGD:S000000542GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmISOSGD:S000002923GO_REF:00000244198
GO:0005829cytosolIDAPMID:168233722317
GO:0005844polysomeISOSGD:S000000542GO_REF:00000245
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPAC1527.03ΔNullPMID:204732893755
MicroscopySPAC1527.03ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopySPAC1527.03ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
143844504386950

UTRs

Region Start End Reference
three_prime_UTR43860874386950PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF05383 Pfam IPR006630 RNA-binding protein Lupus La 330 386 2
SM00715 SMART IPR006630 RNA-binding protein Lupus La 323 406 2
PS50961 Prosite Profiles IPR006630 RNA-binding protein Lupus La 319 408 2
PTHR22792:SF2 HMMPANTHER 12 424 1
PTHR22792 HMMPANTHER 12 424 2
G3DSA:1.10.10.10 Gene3D IPR011991 326 409 44
SSF46785 SuperFamily 320 414 49
Low complexity (SEG) seg 432 444
Low complexity (SEG) seg 160 190
Low complexity (SEG) seg 243 263
Low complexity (SEG) seg 304 321

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.07 Da
Charge 17.00
Isoelectric point 9.52
Molecular weight 53.23 kDa
Number of residues 475
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:195477441192
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5987.73during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
7245.64during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
2.6during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.48during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
sre2membrane-tethered transcription factor Sre2 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
atg1autophagy and CVT pathway serine/threonine protein kinase Atg1 Positive GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
tas3RITS complex subunit 3 Positive GeneticPMID:22681890
par1protein phosphatase regulatory subunit Par1 Positive GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
External References
Database Identifier Description
NBRP SPAC1527.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1527.03 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1527.03 BioGRID Interaction Datasets
Expression Viewer SPAC1527.03 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1527.03 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1527.03 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1527.03 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1527.03 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1527.03 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1527.03 Cell Cycle Data
GEO SPAC1527.03 GEO profiles
PInt SPAC1527.03 Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2541645RNA-binding protein
EntrezGene2541645RNA-binding protein
SPD / RIKEN21/21H12Orfeome Localization Data
UniProtKB/SwissProtQ9P6K0Uncharacterized HTH La-type RNA-binding protein C1527.03
ModBaseQ9P6K0Database of comparative protein structure models
StringQ9P6K0Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594554RNA-binding protein
RefSeq mRNANM_001019983972h- RNA-binding protein (SPAC1527.03), mRNA
European Nucleotide ArchiveCAB90798ENA Protein Mapping
UniParcUPI0000069C08UniProt Archive

Literature for SPAC1527.03

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014