bud6 (SPAC15A10.16)

Gene Standard Namebud6 ChromosomeI
Systematic IDSPAC15A10.16 Gene Start3716643
Synonymsaip3, fat1, SPAC15E1.01 Gene End3720963
Productactin interacting protein 3 homolog Bud6 Gene Length4321
Feature Typeprotein coding CDS Start3716806
Name Description CDS End3720963
Characterisation Statuspublished CDS Length4158

Ensembl Gene Location
  1. ppk3
  2. SPNCRNA.929
  3. SPNCRNA.229
  4. SPNCRNA.930
  5. sgo2
  6. bud6
  7. SPAC15E1.02c
  8. rpl42
  9. SPAC15E1.04
  10. ect1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000644normal protein localizationMicroscopybud6delta (deletion)deletionPMID:18060866
assayed_using arf6
FYPO:0002060viable vegetative cell populationMicroscopybud6delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003779actin bindingISOSGD:S000004311GO_REF:0000024
GO:0005515protein bindingIPImst1PMID:18505873
IPItea1PMID:11516644
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0030036actin cytoskeleton organizationISOSGD:S000004311GO_REF:0000024
GO:0051519activation of bipolar cell growthIMPPMID:11516644
GO:0071963establishment or maintenance of cell polarity regulating cell shapeICGO:0042815GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0030478actin capISOSGD:S000004311GO_REF:0000024
GO:0035838growing cell tip
exists_during pseudohyphal growthIDAPMID:20870879
GO:0035839non-growing cell tip
exists_during pseudohyphal growthIDAPMID:20870879
GO:0051286cell tipIDAPMID:20870879
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
137166433720963

References

Region Start End Reference
five_prime_UTR37166433716805PMID:20118936
five_prime_UTR37166433716805PMID:20118936
five_prime_UTR37166433716805PMID:18641648
five_prime_UTR37166433716805PMID:18641648
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03915 IPR022782 Pfam Actin interacting protein 3, C-terminal 793 1225 1
SM00806 IPR005613 SMART Actin interacting protein 3 793 1225 1
Coil ncoils Rabaptin coiled-coil domain 596 620 974
Coil ncoils Rabaptin coiled-coil domain 1014 1035 974
Coil ncoils Rabaptin coiled-coil domain 492 520 974
Coil ncoils Rabaptin coiled-coil domain 1054 1075 974

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517
PMID:19547744

Protein Properties

Ave. residue weight 111.43 Da
Charge -34.00
Isoelectric point 4.94
Molecular weight 154.33 kDa
Number of residues 1385
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide3469.08PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1835.83PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.4PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi only
conserved in fungi
conserved in eukaryotes
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
ryh1GTPase Ryh1 Synthetic Growth DefectPMID:18931302
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Affinity Capture-WesternPMID:11516644
for3formin For3 Co-localizationPMID:16782006
mst1KAT5 family histone acetyltransferase Mst1 Two-hybridPMID:18505873
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External References
Database Identifier Description
NBRP SPAC15A10.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC15A10.16 Retrieval of eukaryotic orthologs
BioGrid SPAC15A10.16 BioGRID Interaction Datasets
Bähler Lab SPAC15A10.16 Cell Cycle Expression Profile
Bähler Lab SPAC15A10.16 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC15A10.16 Pheromone response/mating expression profiles
Bähler Lab SPAC15A10.16 Environmental stress expression profiles
Bähler Lab SPAC15A10.16 Bähler Lab Transcriptome Viewer
Cyclebase SPAC15A10.16 Cell Cycle Data
PInt SPAC15A10.16 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC15A10.16 Entrez Gene
WikiGene2542756actin-interacting protein 3
Uniprot_genenameFAT1
EntrezGene2542756actin-interacting protein 3
SPD / RIKEN30/30F12Orfeome Localization Data
UniProtKB/SwissProtO13735Actin-interacting protein 3 homolog
ModBaseO13735Database of comparative protein structure models
Pfam Protein DomainsO13735Pfam Domain Arrangement
RefSeq PeptideNP_594302actin-interacting protein 3
RefSeq mRNANM_001019725972h- actin-interacting protein 3 (bud6), mRNA
European Nucleotide ArchiveCAB10112ENA Protein Mapping
UniParcUPI000012A554UniProt Archive

Literature for bud6
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013