nop12 (SPAC16E8.06c)

Gene Standard Namenop12 ChromosomeI
Systematic IDSPAC16E8.06c Gene Start3510077
Synonyms Gene End3508514
ProductRNA-binding protein Nop12 (predicted) Gene Length1564
Feature Typeprotein coding CDS Start3510007
Name Description CDS End3508646
Characterisation Statusbiological_role_inferred CDS Length1362

Ensembl Gene Location
  1. shd1
  2. SPAC16E8.02
  3. gna1
  4. SPAC16E8.04c
  5. mde1
  6. SPNCRNA.914
  7. nop12
  8. SPNCRNA.562
  9. vph1
  10. SPAC16E8.08
  11. scd1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopynop12delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003723RNA bindingISMPFAM:PF00076GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006364rRNA processingISOSGD:S000005401GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005730nucleolusISOSGD:S000005401GO_REF:0000024
IDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
135100773509900
235098543508514

References

Region Start End Reference
three_prime_UTR35086453508514PMID:21511999
three_prime_UTR35086453508514PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00076 IPR000504 Pfam RNA recognition motif domain 272 341 61
PF14259 Pfam 167 256 15
SM00360 IPR000504 SMART RNA recognition motif domain 271 344 69
SM00360 IPR000504 SMART RNA recognition motif domain 165 258 69
PS50102 IPR000504 Prosite Profiles RNA recognition motif domain 270 348 72
PS50102 IPR000504 Prosite Profiles RNA recognition motif domain 164 262 72
G3DSA:3.30.70.330 IPR012677 Gene3D 259 351 82
G3DSA:3.30.70.330 IPR012677 Gene3D 161 258 82
SSF54928 SuperFamily 261 363 78
SSF54928 SuperFamily 154 260 78
Coil ncoils Rabaptin coiled-coil domain 142 166 974
PTHR24011:SF6 hmmpanther 1 365 1
PTHR24011 hmmpanther 1 365 12

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000302rrm RNA recognition motifTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000302

Protein Properties

Ave. residue weight 112.74 Da
Charge 17.50
Isoelectric point 10.06
Molecular weight 49.38 kDa
Number of residues 438
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
antisense transcript detected
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1192.08PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3237.48PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.51PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
par2protein phosphatase regulatory subunit Par2 Positive GeneticPMID:22681890
sum2G2/M transition checkpoint protein Sum2 Positive GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Positive GeneticPMID:22681890
swd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
clp1Cdc14-related protein phosphatase Clp1/Flp1 Affinity Capture-MSPMID:23297348
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:21436456
mlo3RNA binding protein Mlo3 Affinity Capture-MSPMID:21436456
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External References
Database Identifier Description
NBRP SPAC16E8.06c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC16E8.06c Retrieval of eukaryotic orthologs
BioGrid SPAC16E8.06c BioGRID Interaction Datasets
Bähler Lab SPAC16E8.06c Cell Cycle Expression Profile
Bähler Lab SPAC16E8.06c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC16E8.06c Pheromone response/mating expression profiles
Bähler Lab SPAC16E8.06c Environmental stress expression profiles
Bähler Lab SPAC16E8.06c Bähler Lab Transcriptome Viewer
Cyclebase SPAC16E8.06c Cell Cycle Data
PInt SPAC16E8.06c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC16E8.06c Entrez Gene
WikiGene2542314RNA-binding protein Nop12
Uniprot_genenameNOP12
EntrezGene2542314RNA-binding protein Nop12
SPD / RIKEN21/21B05Orfeome Localization Data
UniProtKB/SwissProtO13741Nucleolar protein 12
ModBaseO13741Database of comparative protein structure models
Pfam Protein DomainsO13741Pfam Domain Arrangement
RefSeq PeptideNP_594218RNA-binding protein Nop12
RefSeq mRNANM_001019641972h- RNA-binding protein Nop12 (nop12), mRNA
European Nucleotide ArchiveCAB11047ENA Protein Mapping
UniParcUPI000013AA1FUniProt Archive

Literature for nop12
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013