sua7 (SPAC16E8.16)


Gene Standard Namesua7 Characterisation Statuspublished
Systematic IDSPAC16E8.16 Feature Typeprotein coding
Synonyms Name Description
Producttranscription factor TFIIB Product Size340aa, 36.69 kDa
Genomic Location Chromosome I, 3529970-3532143 (2174nt); CDS:3530337-3531503 (1167nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
TBP-class protein binding RNA polymerase II transcription factor activity1
Annotation ExtensionEvidenceWith/FromReference
zinc ion binding248
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
regulation of transcription from RNA polymerase II promoter292
Annotation ExtensionEvidenceWith/FromReference
transcription initiation from RNA polymerase II promoter37
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationsua7ΔNull1427

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination with normal, unseptated germ tube morphology237
penetrance FYPO_EXT:0000003sua7ΔNull
inviable spore467
penetrance FYPO_EXT:0000001sua7ΔNull
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
135299703530470
235306153532143

UTRs

Region Coordinates Reference
three_prime_UTR3531504..3532143PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00382 Pfam IPR013150 Transcription factor TFIIB, cyclin-like domain 125 195 2
PF00382 Pfam IPR013150 Transcription factor TFIIB, cyclin-like domain 237 306 2
PF08271 Pfam IPR013137 Zinc finger, TFIIB-type 18 62 2
SM00385 SMART IPR013763 Cyclin-like 234 315 13
SM00385 SMART IPR013763 Cyclin-like 123 204 13
PS51134 Prosite Profiles IPR013137 Zinc finger, TFIIB-type 16 49 2
PS00782 Prosite Patterns IPR023486 Transcription factor TFIIB, conserved site 157 172 1
PTHR11618 HMMPANTHER IPR000812 Transcription factor TFIIB 4 323 2
1.10.472.10 Gene3D IPR013763 Cyclin-like 232 327 13
1.10.472.10 Gene3D IPR013763 Cyclin-like 121 208 13
2.20.25.10 Gene3D 14 65 7
SSF47954 SuperFamily IPR013763 Cyclin-like 117 207 15
SSF47954 SuperFamily IPR013763 Cyclin-like 231 326 15
SSF57783 SuperFamily 14 65 8
PR00685 PRINTS IPR000812 Transcription factor TFIIB 165 184 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 235 253 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 71 92 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 269 285 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 56 69 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 301 315 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 34 54 2
PR00685 PRINTS IPR000812 Transcription factor TFIIB 191 206 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.90 Da
Charge 9.00
Isoelectric point 8.76
Molecular weight 36.69 kDa
Number of residues 340
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5139during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
3408during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
4922during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
5742during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
4988during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
855.06during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.6during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
1.8during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3432
conserved in vertebrates3407
conserved in archaea237
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
tfg3transcription factor TFIIF complex subunit Tfg3 Reconstituted ComplexPMID:15616156
External References
Database Identifier Description
NBRP SPAC16E8.16 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC16E8.16 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC16E8.16 BioGRID Interaction Datasets
Expression Viewer SPAC16E8.16 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC16E8.16 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC16E8.16 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC16E8.16 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC16E8.16 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC16E8.16 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC16E8.16 Cell Cycle Data
GEO SPAC16E8.16 GEO profiles
PInt SPAC16E8.16 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC16E8.16 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC16E8.16 Fission yeast phenotypic data & analysis
SPD / RIKEN18/18D10Orfeome Localization Data
UniProtKB/SwissProtO13749Transcription initiation factor IIB
ModBaseO13749Database of comparative protein structure models
STRINGO13749Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594229transcription factor TFIIB
RefSeq mRNANM_001019652972h- transcription factor TFIIB (SPAC16E8.16), mRNA
European Nucleotide ArchiveCAB11044.1ENA Protein Mapping
UniParcUPI0000136C2FUniProt Archive

Literature for sua7

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015