saf3 (SPAC1782.03)


Gene Standard Namesaf3 Characterisation Statuspublished
Systematic IDSPAC1782.03 Feature Typeprotein coding
Synonyms Name Description
Productsplicing associated factor Saf3 Product Size355aa, 40.74 kDa
Genomic Location Chromosome I, 4761230-4763033 (1804nt); CDS:4761807-4762874 (1068nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
mRNA cis splicing, via spliceosome120
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
U2-type spliceosomal complex48
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationsaf3Δ1450

Cell Phenotype

Term NameGenotypesCount
increased pre-mRNA level30
affecting prp2saf3Δ
inviable after spore germination with normal, unseptated germ tube morphologysaf3Δ237
inviable after spore germination, without cell division, septated cells with abnormal cell shapesaf3Δ5
inviable sporesaf3Δ475
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4761230..4763033
5' UTR4761230..4761806PMID:21511999
3' UTR4762875..4763033PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF06991 Pfam IPR009730 Micro-fibrillar-associated protein 1, C-terminal 137 318 1
PTHR15327 HMMPANTHER IPR009730 Micro-fibrillar-associated protein 1, C-terminal 81 354 1
Coil ncoils Predicted coiled-coil protein (DUF2205) 199 241 1050

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.76 Da
Charge -7.00
Codon Adaptation Index 0.36
Isoelectric point 5.32
Molecular weight 40.74 kDa
Number of residues 355
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS347 1675
Annotation ExtensionEvidenceResidueReference
experimental evidence S347 PMID:24763107
phosphorylated residue 1930
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for saf3 (SPAC1782.03)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
208.17during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.2during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
no apparent S. cerevisiae ortholog599
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3422
conserved in vertebrates3397
conserved in eukaryotes only2504
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load gene that interact physically with SPAC1782.03 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bypaa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:24634168
Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPAC1782.03 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:18818364
negative genetic interaction withSPAC23H3.15cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withadn3transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmdm31mitochondrial inner membrane protein Mdm31 Negative GeneticPMID:22681890
negative genetic interaction withSPAC11D3.155-oxoprolinase (ATP-hydrolizing) (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withpck1protein kinase C (PKC)-like Pck1 Negative GeneticPMID:22681890
negative genetic interaction withgma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
negative genetic interaction withpuf1pumilio family RNA-binding protein Puf1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmpc2mitochondrial pyruvate transmembrane transporter Mpc2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpam17TIM23 translocase complex-associated motor subunit Pam17 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC1F5.03cFAD-dependent oxidoreductase involved in late endosome to Golgi transport (predicted) Negative GeneticPMID:22681890
negative genetic interaction withbdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:18818364
negative genetic interaction withgpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
negative genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Negative GeneticPMID:22681890
negative genetic interaction withSPCC4F11.03cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:18818364
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
negative genetic interaction withmph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
negative genetic interaction withrad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:22681890
negative genetic interaction withyox1MBF complex corepressor Yox1 Negative GeneticPMID:22681890
negative genetic interaction withswd3WD repeat protein Swd3 Negative GeneticPMID:22681890
negative genetic interaction withSPBC16G5.07cstomatin, mitochondrial membrane organization protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC3H7.05cmitochondrial Membrane Bound O-Acyl Transferase (MBOAT) family Negative GeneticPMID:22681890
negative genetic interaction withprz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
negative genetic interaction withSPBC651.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withyam8stretch-activated calcium ion channel Yam8 Negative GeneticPMID:22681890
negative genetic interaction withget4ER membrane insertion protein Get4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAP32A8.02xylose and arabinose reductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgid9GID complex subunit Gid9 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBP4H10.17ccarboxyl methyl esterase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
negative genetic interaction withkap113karyopherin Kap113 Negative GeneticPMID:22681890
negative genetic interaction withSPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpsh3ER chaperone SHR3 homologue Psh3 Negative GeneticPMID:22681890
negative genetic interaction withptc3protein phosphatase 2c homolog 3 Negative GeneticPMID:22681890
negative genetic interaction withalg12dolichyl pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase Alg12 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withskb5Shk1 kinase binding protein 5 Negative GeneticPMID:22681890
negative genetic interaction withpom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
negative genetic interaction withrho3Rho family GTPase Rho3 Negative GeneticPMID:22681890
negative genetic interaction withcfh1chitin synthase regulatory factor-like Cfh1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withalg5dolichyl-phosphate beta-glucosyltransferase Alg5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withuge1UDP-glucose 4-epimerase Uge1 Negative GeneticPMID:22681890
negative genetic interaction withssa1heat shock protein Ssa1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmug113T5orf172 family protein Negative GeneticPMID:22681890
negative genetic interaction withatb2tubulin alpha 2 Negative GeneticPMID:22681890
negative genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmak3histidine kinase Mak3 Negative GeneticPMID:22681890
negative genetic interaction withmed13mediator complex subunit Med13 Negative GeneticPMID:22681890
negative genetic interaction withtos4FHA domain protein Tos4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpho84inorganic phosphate transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfsv1SNARE Fsv1 Negative GeneticPMID:22681890
negative genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:22681890
negative genetic interaction withmal3EB1 family Mal3 Negative GeneticPMID:18818364
negative genetic interaction withrud3Golgi matrix protein Rud3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl35b60S ribosomal protein L35a (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpof9F-box protein Pof9 Negative GeneticPMID:22681890
negative genetic interaction withpmp1dual-specificity MAP kinase phosphatase Pmp1 Negative GeneticPMID:18818364
negative genetic interaction withalg10dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase Alg10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmto1MT organizer Mto1 Negative GeneticPMID:22681890
negative genetic interaction withzfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Negative GeneticPMID:22681890
negative genetic interaction withSPAC7D4.12cDUF1212 family protein Negative GeneticPMID:22681890
negative genetic interaction withcgs2cAMP-specific phosphodiesterase Cgs2 Negative GeneticPMID:22681890
negative genetic interaction withSPAC1296.01cphosphoacetylglucosamine mutase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC6B12.04c2-aminoadipate transaminase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC16G5.09serine carboxypeptidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsnt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
negative genetic interaction withnup124nucleoporin Nup124 Negative GeneticPMID:22681890
negative genetic interaction withsol1SWI/SNF complex subunit Sol1 Negative GeneticPMID:22681890
negative genetic interaction withtip1CLIP170 family protein Tip1 Negative GeneticPMID:22681890
negative genetic interaction withpmk1MAP kinase Pmk1 Negative GeneticPMID:18818364
negative genetic interaction withsro7Lgl family protein Sro7 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmrt4mRNA turnover and ribosome assembly protein Mrt4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnrp1RNA-binding protein Negative GeneticPMID:22681890
negative genetic interaction withmso1endocytic docking protein Mso1 Negative GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
negative genetic interaction withfar10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
negative genetic interaction withrpl170260S ribosomal protein L17 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
negative genetic interaction withhhf2histone H4 h4.2 Negative GeneticPMID:22681890
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
negative genetic interaction withgmh4alpha-1,2-galactosyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1198.06cmannan endo-1,6-alpha-mannosidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
negative genetic interaction withalp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:18818364
negative genetic interaction withSPAC23H4.16cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC13G6.15ccalcipressin (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsds23PP2A-type phosphatase inhibitor Sds23/Moc1 Negative GeneticPMID:22681890
negative genetic interaction withubp7ubiquitin C-terminal hydrolase Ubp7 Negative GeneticPMID:18818364
negative genetic interaction withdep1Sds3-like family protein Dep1 Negative GeneticPMID:22681890
negative genetic interaction withSPBC28E12.02RNA-binding protein Negative GeneticPMID:22681890
negative genetic interaction withgcs2glutamate-cysteine ligase regulatory subunit Gcs2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmug123Schizosaccharomyces specific protein Mug123 Negative GeneticPMID:22681890
negative genetic interaction withSPCC1795.10cSed5 Vesicle Protein Svp26 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps38phophatidylinositol 3-kinase complex subunit Vps38 Negative GeneticPMID:22681890
negative genetic interaction withnem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcys11cysteine synthase Negative GeneticPMID:22681890
negative genetic interaction withswd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
negative genetic interaction withvps71Swr1 complex subunit Vps71 Negative GeneticPMID:18818364
negative genetic interaction withhos2histone deacetylase (class I) Hos2 Negative GeneticPMID:22681890
negative genetic interaction withpan52-dehydropantoate 2-reductase Pan5 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withcch1calcium ion channel Cch1 Negative GeneticPMID:22681890
negative genetic interaction withexo70exocyst complex subunit Exo70 Negative GeneticPMID:22681890
negative genetic interaction withSPCC550.11karyopherin (predicted) Negative GeneticPMID:22681890
negative genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:18818364
negative genetic interaction withrad13DNA repair nuclease Rad13 Negative GeneticPMID:22681890
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:18818364
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
negative genetic interaction withfrp1ferric-chelate reductase Frp1 Negative GeneticPMID:22681890
negative genetic interaction withgit5heterotrimeric G protein beta subunit Git5 Negative GeneticPMID:22681890
negative genetic interaction withmto2MT organizer Mto2 Negative GeneticPMID:22681890
negative genetic interaction withSPBC2G5.01ER protein involved in ER-nucleus signaling (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpar1protein phosphatase PP2A regulatory subunit B-56 Par1 Negative GeneticPMID:18818364
negative genetic interaction withliz1pantothenate transmembrane transporter Liz1 Negative GeneticPMID:22681890
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
negative genetic interaction withvac7Vac7 ortholog (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrga8Rho-type GTPase activating protein Rga8 Negative GeneticPMID:22681890
negative genetic interaction withspf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
negative genetic interaction witherg28Erg28 protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtea2kinesin-like protein Tea2 Negative GeneticPMID:18818364
negative genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
negative genetic interaction withSPAC23C4.09cDNA-binding TFAR19-related protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmac1membrane anchored protein Mac1 Negative GeneticPMID:22681890
negative genetic interaction withdga1diacylglycerol O-acyltransferase Dga1 Negative GeneticPMID:22681890
negative genetic interaction withrod1arrestin/PY protein involved in ubiquitin-mediated endocytosis Rod1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpar2protein phosphatase PP2A regulatory subunit B-56 Par2 Negative GeneticPMID:22681890
negative genetic interaction withwtf16wtf element Wtf16 Negative GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
negative genetic interaction withpus1tRNA pseudouridine synthase Lsp1 Negative GeneticPMID:18818364
negative genetic interaction withrem1meiosis-specific cyclin Rem1 Negative GeneticPMID:18818364
negative genetic interaction withSPBC18A7.01X-Pro dipeptidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC126.08clectin family glycoprotein receptor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmfr1fizzy-related protein Mfr1 Negative GeneticPMID:22681890
negative genetic interaction witherp2COPII-coated vesicle component Erp2/3/4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witharg12argininosuccinate synthase Arg12 Negative GeneticPMID:22681890
negative genetic interaction withSPBC660.17cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withell1RNA polymerase II transcription elongation factor SpELL Negative GeneticPMID:22681890
negative genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Negative GeneticPMID:22681890
negative genetic interaction withwbp4WW domain-binding protein Wbp4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:18818364
positive genetic interaction withemc1ER membrane protein complex subunit Emc1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsyj1inositol-polyphosphate 5-phosphatase (synaptojanin homolog 1) Positive GeneticPMID:22681890
positive genetic interaction withurg2uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withgdh2NAD-dependent glutamate dehydrogenase Gdh2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpcl1ferrous iron/manganese transmembrane transporter Pcl1 Positive GeneticPMID:22681890
positive genetic interaction withppk9serine/threonine protein kinase Ppk9 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPCC18.17cproteasome assembly chaperone (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC3A11.10cdipeptidyl peptidase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatp14F1-ATPase subunit H (predicted) Positive GeneticPMID:22681890
positive genetic interaction withgim3prefoldin subunit 4, Gim3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfhl1forkhead transcription factor Fhl1 Positive GeneticPMID:22681890
positive genetic interaction withSPAC22A12.14cBSD domain protein, unknown biological role Positive GeneticPMID:22681890
positive genetic interaction withset6histone lysine methyltransferase Set6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmid1medial ring protein Mid1 Positive GeneticPMID:22681890
positive genetic interaction withbop1ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1271.03cNLI interacting factor family phosphatase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC1604.12Schizosaccharomyces specific phosphoprotein Positive GeneticPMID:22681890
positive genetic interaction withptf1Mst2 histone acetytransferase acytyltransferase complex, predicted phosphoric monoester hydrolase Ptf1 Positive GeneticPMID:22681890
positive genetic interaction withSPAC2F3.07cSchizosaccharomyces pombe specific protein Positive GeneticPMID:22681890
positive genetic interaction withcip1RNA-binding protein Cip1 Positive GeneticPMID:22681890
positive genetic interaction witheif21translation initiation factor eIF2A (predicted) Positive GeneticPMID:22681890
positive genetic interaction withnop12RNA-binding protein Nop12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtrs8502TRAPP complex subunit Trs85b (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsdh3succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted) Positive GeneticPMID:22681890
positive genetic interaction withppr8mitochondrial PPR repeat protein Ppr8 Positive GeneticPMID:22681890
positive genetic interaction withtrk1potassium ion transmembrane transporter Trk1 Positive GeneticPMID:22681890
positive genetic interaction withdad2DASH complex subunit Dad2 Positive GeneticPMID:22681890
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatg16autophagy protein Atg16 Positive GeneticPMID:22681890
positive genetic interaction withSPCC594.01DUF1769 family protein Positive GeneticPMID:22681890
positive genetic interaction withvms1Cdc48p-Npl4p-Vms1p AAA ATPase complex subunit involved in ER associated ubiquitin-dependent protein catabolic process Vms1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withupf3up-frameshift suppressor 3 family protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withvta1Vps20 associated protein Vta1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withubp2ubiquitin C-terminal hydrolase Ubp2 Positive GeneticPMID:22681890
positive genetic interaction withSPBC30D10.03cIMP 5'-nucleotidase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatg5autophagy associated protein Atg5 Positive GeneticPMID:22681890
positive genetic interaction withmkh1MEK kinase (MEKK) Mkh1 Positive GeneticPMID:22681890
positive genetic interaction withyip5Rab GTPase binding Yip5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC8C9.05D-Tyr-tRNA deacylase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withset10ribosomal lysine methyltransferase Set10 Positive GeneticPMID:22681890
positive genetic interaction withtrm112protein and tRNA methyltransferase regulatory subunit Trm112 (predicted) Positive GeneticPMID:22681890
positive genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Positive GeneticPMID:22681890
positive genetic interaction withpek1MAP kinase kinase Pek1 Positive GeneticPMID:22681890
positive genetic interaction withatg101autophagy protein Atg101 Positive GeneticPMID:22681890
positive genetic interaction withmug33Tea1-interacting protein involved in exocytosis Positive GeneticPMID:22681890
positive genetic interaction withrps280240S ribosomal protein S28, Rps2802 Positive GeneticPMID:22681890
positive genetic interaction withupf1ATP-dependent RNA helicase Upf1 Positive GeneticPMID:22681890
positive genetic interaction withgms1UDP-galactose transmembrane transporter Gms1 Positive GeneticPMID:22681890
positive genetic interaction withmfm3M-factor precursor Mfm3 Positive GeneticPMID:22681890
positive genetic interaction withSPAPB1E7.11cSchizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withalm1medial ring protein Alm1 Positive GeneticPMID:22681890
positive genetic interaction withtal1transaldolase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC17H9.08mitochondrial coenzyme A transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmhf2kinetochore protein, CENP-X ortholog, FANCM-MHF complex subunit Mhf2 Positive GeneticPMID:22681890
positive genetic interaction withSPAC2G11.04RNA-binding protein, G-patch type, splicing factor 45 ortholog (predicted) Positive GeneticPMID:22681890
positive genetic interaction withfsc1fasciclin domain protein Fsc1 Positive GeneticPMID:22681890
positive genetic interaction withSPAC18G6.13Schizosaccharomyces specific protein Positive GeneticPMID:22681890
positive genetic interaction withvps25ESCRT II complex subunit Vps25 Positive GeneticPMID:22681890
positive genetic interaction withsry1serine racemase Sry1 Positive GeneticPMID:22681890
positive genetic interaction withSPAC1F12.04cconserved fungal protein Positive GeneticPMID:22681890
positive genetic interaction withcid12poly(A) polymerase Cid12 Positive GeneticPMID:18818364
positive genetic interaction withctu1cytosolic thiouridylase subunit Ctu1 Positive GeneticPMID:22681890
positive genetic interaction withbob1prefoldin subunit 5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpmk1MAP kinase Pmk1 Positive GeneticPMID:22681890
positive genetic interaction withgar2nucleolar protein required for rRNA processing Positive GeneticPMID:22681890
positive genetic interaction withelp6elongator complex subunit Elp6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmug184Hsp70 protein binding protein Mug184 Positive GeneticPMID:22681890
positive genetic interaction withwtf15wtf element Wtf15 Positive GeneticPMID:22681890
positive genetic interaction withivn1CDC50 domain protein, implicated in signal transduction (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC887.17transmembrane transporter (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC29A10.16ccytochrome b5 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC5H10.01DUF1445 family mitochondrial protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withnts1Clr6 histone deacetylase complex subunit Nts1 Positive GeneticPMID:22681890
positive genetic interaction withidp1isocitrate dehydrogenase Idp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsyn1synaptotagmin family C2 domain protein, Syn1 Positive GeneticPMID:22681890
positive genetic interaction witharp6actin-like protein Arp6 Positive GeneticPMID:22681890
positive genetic interaction withSPAC1142.02cTPR repeat protein, SGT2 family (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatg10Atg12 conjugating activity Atg10 Positive GeneticPMID:22681890
positive genetic interaction withmgr2TIM23 translocase complex subunit Mgr2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction witheri1double-strand siRNA ribonuclease Eri1 Positive GeneticPMID:22681890
positive genetic interaction withscs7sphingosine hydroxylase Scs7 Positive GeneticPMID:18818364
positive genetic interaction withuba42thiosulfate sulfurtransferase, URM1 activating enzyme E1-type Uba42 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withapq12nuclear membrane organization protein Apq12 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withrrg9mitochondrial genome maintenance protein Rrg9 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withpmt3SUMO Positive GeneticPMID:22681890
positive genetic interaction withsnr13-hydroxyisobutyryl-CoA hydrolase snr1 Positive GeneticPMID:22681890
positive genetic interaction withdhx29ATP-dependent RNA helicase, human DHX29 ortholog (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPBC30B4.06cmitochondrial GIDA family tRNA uridine 5-carboxymethylaminomethyl modification enzyme (predicted) Positive GeneticPMID:22681890
positive genetic interaction withppk6serine/threonine protein kinase Ppk6 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withaip1actin cortical patch component Aip1 Positive GeneticPMID:22681890
positive genetic interaction withSPCC1919.13cribosome biogenesis protein (predicted) Positive GeneticPMID:18818364
positive genetic interaction withswi6HP1 family chromodomain protein Swi6 Positive GeneticPMID:22681890
positive genetic interaction withpmc1vacuolar calcium transporting P-type ATPase P2 type, Pmc1 Positive GeneticPMID:22681890
positive genetic interaction withmvp1sorting nexin Mvp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withmrpl1mitochondrial ribosomal protein subunit L1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withswc2Swr1 complex complex subunit Swc2 Positive GeneticPMID:22681890
positive genetic interaction withatg9autophagy associated protein Atg9 Positive GeneticPMID:22681890
positive genetic interaction withntp1alpha,alpha-trehalase Ntp1 Positive GeneticPMID:22681890
positive genetic interaction withSPAC227.17cconserved eukaryotic protein, DUF3128, human c22orf39 ortholog Positive GeneticPMID:22681890
positive genetic interaction withtrx2mitochondrial thioredoxin Trx2 Positive GeneticPMID:22681890
positive genetic interaction withelp1elongator subunit Elp1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withSPAC4A8.06cesterase/lipase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatp10mitochondrial F1-F0 ATPase assembly protein (predicted) Positive GeneticPMID:22681890
positive genetic interaction withhht3histone H3 h3.3 Positive GeneticPMID:22681890
positive genetic interaction withatg17autophagy associated protein kinase activator Atg17 Positive GeneticPMID:22681890
positive genetic interaction withSPCC1494.08cconserved fungal protein Positive GeneticPMID:22681890
rescuescdc7serine/threonine protein kinase Cdc7 Phenotypic SuppressionPMID:22267499
synthetically rescuessid2NDR kinase Sid2 Synthetic RescuePMID:22267499
synthetically rescuescdc7serine/threonine protein kinase Cdc7 Synthetic RescuePMID:22267499
synthetically rescuescdc14SIN component Cdc14 Synthetic RescuePMID:22267499
synthetically rescuesspg1GTPase Spg1 Synthetic RescuePMID:22267499
synthetically rescuesetd1ethanol-dependent mutant protein Etd1 Synthetic RescuePMID:22267499
synthetically rescuesplo1Polo kinase Plo1 Synthetic RescuePMID:22267499
synthetically rescuescdc11SIN component scaffold protein, centriolin ortholog Cdc11 Synthetic RescuePMID:22267499
synthetically rescuesmob1Sid2-Mob1 kinase complex regulatory subunit Mob1 Synthetic RescuePMID:22267499
synthetic growth defect withpab1protein phosphatase PP2A regulatory subunit B-55 Pab1 Synthetic Growth DefectPMID:22267499
synthetic growth defect withppa1minor serine/threonine protein phosphatase Ppa1 Synthetic Growth DefectPMID:22267499
synthetic growth defect withcdc16two-component GAP Cdc16 Synthetic Growth DefectPMID:22267499
synthetic growth defect withpar1protein phosphatase PP2A regulatory subunit B-56 Par1 Synthetic Growth DefectPMID:22267499
synthetic lethal withppa2serine/threonine protein phosphatase Ppa2 Synthetic LethalityPMID:22267499
synthetic lethal withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Synthetic LethalityPMID:22267499
External References
Database Identifier Description
NBRP SPAC1782.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1782.03 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1782.03 BioGRID Interaction Datasets
Expression Viewer SPAC1782.03 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1782.03 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1782.03 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1782.03 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1782.03 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1782.03 Transcriptome Viewer (Bähler Lab)
GEO SPAC1782.03 GEO profiles
PInt SPAC1782.03 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1782.03 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1782.03 Fission yeast phenotypic data & analysis
Cyclebase SPAC1782.03.1 Cell Cycle Data
SPD / RIKEN16/16D05Orfeome Localization Data
UniProtKB/SwissProtQ9P7H6Uncharacterized protein C1782.03
ModBaseQ9P7H6Database of comparative protein structure models
STRINGQ9P7H6Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594710splicing associated factor Saf3
RefSeq mRNANM_001020137972h- splicing associated factor Saf3 (saf3), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAB76265ENA Protein Mapping
UniParcUPI000006ADAAUniProt Archive

Literature for saf3

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Release Version: PomBase:30_57 - 27 Jan 2016