saf3 (SPAC1782.03)

Gene Standard Namesaf3 ChromosomeI
Systematic IDSPAC1782.03 Gene Start4761230
Synonyms Gene End4763033
Productsplicing associated factor Saf3 Gene Length1804
Feature Typeprotein coding CDS Start4761807
Name Description CDS End4762874
Characterisation Statuspublished CDS Length1068

Ensembl Gene Location
  1. SPNCRNA.1022
  2. mug67
  3. ecm29
  4. SPAC1782.02c
  5. saf3
  6. cox24
  7. ypa2
  8. phb1
  9. qcr8
  10. rex3
  11. SPNCRNA.1023
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001489inviable vegetative cellMicroscopysaf3delta (deletion)deletionPMID:20473289
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
147612304763033

References

Region Start End Reference
three_prime_UTR47628754763033PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF06991 IPR009730 Pfam Micro-fibrillar-associated protein 1, C-terminal 95 353 1
Coil ncoils Rabaptin coiled-coil domain 199 242 974
PTHR15327 IPR009730 hmmpanther Micro-fibrillar-associated protein 1, C-terminal 32 355 1
PTHR15327:SF0 hmmpanther 32 355 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:19547744

Protein Properties

Ave. residue weight 114.76 Da
Charge -7.00
Isoelectric point 5.32
Molecular weight 40.74 kDa
Number of residues 355
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide208.17PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.4PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.2PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
prp19ubiquitin-protein ligase E4 Affinity Capture-MSPMID:21386897
prp3U4/U6 x U5 tri-snRNP complex subunit Prp3 (predicted) Affinity Capture-MSPMID:21386897
sap62zinc finger protein Sap62 Affinity Capture-MSPMID:21386897
cwf3complexed with Cdc5 protein Cwf3 Affinity Capture-MSPMID:21386897
prp38U4/U6 x U5 tri-snRNP complex subunit Prp38 (predicted) Affinity Capture-MSPMID:21386897
dre4splicing associated factor Dre4 Affinity Capture-MSPMID:21386897
cwf10GTPase Cwf10 (predicted) Affinity Capture-MSPMID:21386897
rsd1RNA-binding protein Rsd1 (predicted) Affinity Capture-MSPMID:21386897
mug64BAR domain protein (predicted) Affinity Capture-MSPMID:21386897
sap145U2 snRNP-associated protein Sap145 (predicted) Affinity Capture-MSPMID:21386897
cwf26complexed with Cdc5 protein Cwf26 Affinity Capture-MSPMID:21386897
spf38splicing factor Spf38 Affinity Capture-MSPMID:21386897
SPAC227.12U4/U6 x U5 tri-snRNP complex subunit Prp4 family (predicted) Affinity Capture-MSPMID:21386897
cdc5cell division control protein, splicing factor Cdc5 Affinity Capture-MSPMID:21386897
prp31U4/U6 x U5 tri-snRNP complex subunit Prp31 Affinity Capture-MSPMID:21386897
sap61U2 snRNP-associated protein sap61 Affinity Capture-MSPMID:21386897
saf2splicing associated factor Saf2 Affinity Capture-MSPMID:21386897
prp2U2AF large subunit (U2AF-59) Affinity Capture-MSPMID:21386897
cwf4complexed with Cdc5 protein Cwf4 Affinity Capture-MSPMID:21386897
smb1Sm snRNP core protein Smb1 Affinity Capture-MSPMID:21386897
cwf29RNA-binding protein Cwf29 Affinity Capture-MSPMID:21386897
cwf7splicing factor Cwf7 Affinity Capture-MSPMID:21386897
brr2U5 snRNP complex subunit Brr2 (predicted) Affinity Capture-MSPMID:21386897
spp42U5 snRNP complex subunit Spp42 Affinity Capture-MSPMID:21386897
prp10U2 snRNP-associated protein Sap155 Affinity Capture-MSPMID:21386897
smg1U4/U6 x U5 tri-snRNP complex Sm snRNP core protein Smg1 Affinity Capture-MSPMID:21386897
lea1U2 snRNP-associated protein Lea1 (predicted) Affinity Capture-MSPMID:21386897
sap114splicing factor Sap114 Affinity Capture-MSPMID:21386897
prp12U2 snRNP-associated protein Sap130 (predicted) Affinity Capture-MSPMID:21386897
prp5WD repeat protein Prp5 Affinity Capture-MSPMID:21386897
cwf5RNA-binding protein Cwf5 Affinity Capture-MSPMID:21386897
smd1Sm snRNP core protein Smd1 Affinity Capture-MSPMID:21386897
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Affinity Capture-MSPMID:21386897
snu23U4/U6 x U5 tri-snRNP complex subunit Snu23 (predicted) Affinity Capture-MSPMID:21386897
snu66U4/U6 x U5 tri-snRNP complex subunit Snu66 (predicted) Affinity Capture-MSPMID:21386897
prp45splicing factor Prp45 Affinity Capture-MSPMID:21386897
smd3Sm snRNP core protein Smd3 Affinity Capture-MSPMID:21386897
spf30splicing factor Spf30 (predicted) Affinity Capture-MSPMID:21386897
sab14U2 snRNP-associated protein SF3B14 ortholog (predicted) Affinity Capture-MSPMID:21386897
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External References
Database Identifier Description
NBRP SPAC1782.03 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1782.03 Retrieval of eukaryotic orthologs
BioGrid SPAC1782.03 BioGRID Interaction Datasets
Bähler Lab SPAC1782.03 Cell Cycle Expression Profile
Bähler Lab SPAC1782.03 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1782.03 Pheromone response/mating expression profiles
Bähler Lab SPAC1782.03 Environmental stress expression profiles
Bähler Lab SPAC1782.03 Bähler Lab Transcriptome Viewer
Cyclebase SPAC1782.03 Cell Cycle Data
PInt SPAC1782.03 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC1782.03 Entrez Gene
WikiGene2542348microfibrillar-associated protein family protein
EntrezGene2542348microfibrillar-associated protein family protein
SPD / RIKEN16/16D05Orfeome Localization Data
UniProtKB/SwissProtQ9P7H6Uncharacterized protein C1782.03
ModBaseQ9P7H6Database of comparative protein structure models
Pfam Protein DomainsQ9P7H6Pfam Domain Arrangement
RefSeq PeptideNP_594710microfibrillar-associated protein family protein
RefSeq mRNANM_001020137972h- microfibrillar-associated protein family protein (SPAC1782.03), mRNA
European Nucleotide ArchiveCAB76265ENA Protein Mapping
SPD / RIKEN16/16D05Orfeome Localization Data

Literature for saf3
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013