clp1 (SPAC1782.09c)

Gene Standard Nameclp1 ChromosomeI
Systematic IDSPAC1782.09c Gene Start4771708
Synonymsflp1 Gene End4769991
ProductCdc14-related protein phosphatase Clp1/Flp1 Gene Length1718
Feature Typeprotein coding CDS Start4771659
Name Description CDS End4769991
Characterisation Statuspublished CDS Length1669

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000023small cellclp1delta (deletion)deletionPMID:11448769
FYPO:0000091sensitive to thiabendazolecompetitive growth assay evidenceclp1delta (deletion)deletionPMID:20537132
FYPO:0000269sensitive to microtubule depolymerizing drugscompetitive growth assay evidenceclp1delta (deletion)deletionPMID:20537132
FYPO:0000648small viable vegetative cellMicroscopyclp1delta (deletion)deletionPECO:0000137PMID:22624651
FYPO:0002060viable vegetative cell populationMicroscopyclp1delta (deletion)deletionPMID:20473289
no_name (unrecorded)unrecordedPMID:11683392
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0004721phosphoprotein phosphatase activityIDAPMID:15128870
has_direct_input ase1IDAPMID:19666868
has_direct_input klp9IDAPMID:19666868
GO:0004725protein tyrosine phosphatase activityIEAEC:3.1.3.48GO_REF:0000003
GO:0004864protein phosphatase inhibitor activity
has_direct_input cdc25IDAPMID:15128870
GO:0005515protein bindingIPIdnt1PMID:17538026
gene_product_form_id PR:000027629IPIrad24PMID:16085489
IPIcdc25PMID:15128870
IPIark1PMID:15525536
GO:0008138protein tyrosine/serine/threonine phosphatase activityIEAIPR000340GO_REF:0000002
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0000070mitotic sister chromatid segregationIMPPMID:15525536
GO:0000087M phase of mitotic cell cycleNASGO_REF:0000051
GO:0000917barrier septum assemblyIMPPMID:11683392
GO:0006470protein dephosphorylationICGO:0004721GO_REF:0000001
GO:0007096regulation of exit from mitosisIMPPMID:15128870
GO:0008608attachment of spindle microtubules to kinetochoreIGIdis1PMID:15525536
GO:0010389regulation of G2/M transition of mitotic cell cycleIMPPMID:11448769
GO:0010972negative regulation of G2/M transition of mitotic cell cycleIMPPMID:22624651
GO:0031031positive regulation of septation initiation signaling cascadeTASPMID:11683392
GO:0031134sister chromatid biorientationIMPPMID:15525536
GO:0031565cytokinesis checkpointIMPPMID:15265986
IMPPMID:11448769
GO:0031566actomyosin contractile ring maintenanceIMPPMID:18378776
GO:0034613cellular protein localization
has_input bir1IMPPMID:15525536
has_input ark1IMPPMID:15525536
GO:0035853chromosome passenger complex localization to spindle midzoneIMPPMID:19570910
GO:0045736negative regulation of cyclin-dependent protein serine/threonine kinase activityIGIcdc25PMID:11683392
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0000778condensed nuclear chromosome kinetochore
exists_during mitotic prometaphaseIDAPMID:15525536
GO:0005634nucleusIDAPMID:16823372
GO:0005730nucleolus
exists_during interphase of mitotic cell cycleIDAPMID:11448769
GO:0005737cytoplasm
exists_during mitotic cell cycleIDAPMID:11448769
GO:0005816spindle pole body
exists_during mitotic cell cycleIDAPMID:11448769
GO:0005826actomyosin contractile ring
colocalizes_withIDAPMID:11448769
GO:0031097medial cortex
exists_during mitotic cell cycleIDAPMID:11448769
GO:0044732mitotic spindle pole bodyIDAPMID:16823372
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
147717084771611
247715554769991

References

Region Start End Reference
five_prime_UTR47717084771660PMID:20118936
five_prime_UTR47717084771660PMID:20118936
five_prime_UTR47717084771660PMID:18641648
five_prime_UTR47717084771660PMID:18641648
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00782 IPR000340 Pfam Dual specificity phosphatase, catalytic domain 236 329 4
PS50056 IPR000387 Prosite Profiles Protein-tyrosine/Dual specificity phosphatase 267 331 6
PS00383 IPR016130 Prosite Patterns Protein-tyrosine phosphatase, active site 284 294 7
G3DSA:3.90.190.10 Gene3D 145 333 8
G3DSA:3.90.190.10 Gene3D 7 144 8
SSF52799 SuperFamily 170 339 9
SSF52799 SuperFamily 7 164 9
PTHR23339:SF22 IPR026070 hmmpanther 9 352 1
PTHR23339 hmmpanther 9 352 1

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residueevidenceInferred from Sequence or Structural SimilarityPMID:11683392

Protein Properties

Ave. residue weight 112.20 Da
Charge 18.00
Isoelectric point 9.18
Molecular weight 60.25 kDa
Number of residues 537
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide1667.16PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide417.9PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide1PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005
population_wide3.3PMID:23101633
Complementation
DescriptionQualifierReference
functionally complemented by human CDC14 PMID:15911625
Miscellaneous Functional Group
DescriptionQualifierReference
nucleocytoplasmic shuttling protein PMID:16085490
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dis1microtubule-associated protein Dis1 Synthetic Growth DefectPMID:15525536
Synthetic Growth DefectPMID:16085490
tea2kinesin-like protein Tea2 Synthetic Growth DefectPMID:18931302
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
sce3translation initiation factor (predicted) Negative GeneticPMID:22681890
hhp2serine/threonine protein kinase Hhp2 Negative GeneticPMID:22681890
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
SPAC17G8.08chuman TMEM165 homolog Positive GeneticPMID:22681890
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
sol1SWI/SNF complex subunit Sol1 Phenotypic EnhancementPMID:22624651
sid2NDR kinase Sid2 Synthetic LethalityPMID:11683392
Synthetic LethalityPMID:15857958
mid1medial ring protein Mid1 Phenotypic EnhancementPMID:21098635
sep1forkhead transcription factor Sep1 Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
mug113T5orf172 family protein Negative GeneticPMID:22681890
hmt2sulfide-quinone oxidoreductase Negative GeneticPMID:22681890
mph1dual specificity protein kinase Mph1 Negative GeneticPMID:22681890
gtb1gamma-tubulin Gtb1 Synthetic Growth DefectPMID:22737087
atp11F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
nup124nucleoporin Nup124 Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
sts5RNB-like protein Negative GeneticPMID:22681890
ase1antiparallel microtubule cross-linking factor Ase1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
erd1Erd1 homolog (predicted) Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
wee1M phase inhibitor protein kinase Wee1 Phenotypic EnhancementPMID:11683392
Phenotypic Suppression
nem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
snf5SWI/SNF complex subunit Snf5 Phenotypic EnhancementPMID:22624651
bdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:22681890
dis2serine/threonine protein phosphatase PP1 Phenotypic EnhancementPMID:21965289
cdc11SIN component scaffold protein, centriolin ortholog Cdc11 Synthetic LethalityPMID:11683392
SPCC1442.14cadenosine 5'-monophosphoramidase (predicted) Negative GeneticPMID:22681890
cdc7serine/threonine protein kinase Cdc7 Synthetic LethalityPMID:11683392
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
rng2IQGAP Synthetic Growth DefectPMID:15265986
SPAC3A12.13ctranslation initiation factor eIF3j (p35) Negative GeneticPMID:22681890
SPCC338.18sequence orphan Positive GeneticPMID:22681890
cdc2cyclin-dependent protein kinase Cdk1/Cdc2 Synthetic LethalityPMID:16950131
Phenotypic EnhancementPMID:11683392
Phenotypic Suppression
Synthetic RescuePMID:23297348
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
csk1cyclin-dependent kinase activating kinase Csk1 Negative GeneticPMID:22681890
fkh2forkhead transcription factor Fkh2 Synthetic LethalityPMID:21098641
chp1chromodomain protein Chp1 Negative GeneticPMID:22681890
pmp1dual-specificity MAP kinase phosphatase Pmp1 Negative GeneticPMID:22681890
SPCC1840.09NAD dependent epimerase/dehydratase family protein Negative GeneticPMID:22681890
cdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Phenotypic EnhancementPMID:22624651
bgs11,3-beta-glucan synthase catalytic subunit Bgs1 Synthetic Growth DefectPMID:15265986
far8SIP/FAR complex striatin subunit, Far8/Csc3 Negative GeneticPMID:22681890
set3histone lysine methyltransferase Set3 Phenotypic EnhancementPMID:22347452
mad2spindle checkpoint protein Mad2 Synthetic Growth DefectPMID:22737087
php5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
cdc16two-component GAP Cdc16 Phenotypic EnhancementPMID:15265986
Phenotypic EnhancementPMID:11683392
alp31tubulin specific chaperone cofactor A, Alp31 Negative GeneticPMID:22681890
ilv1acetolactate synthase catalytic subunit Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
SPBC651.04sequence orphan Negative GeneticPMID:22681890
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:22681890
plo1Polo kinase Plo1 Synthetic Growth DefectPMID:21098641
Synthetic Rescue
Synthetic LethalityPMID:15857958
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
dma1mitotic spindle checkpoint protein Dma1 Synthetic RescuePMID:12479804
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Phenotypic EnhancementPMID:22624651
lsc1Lsk1 associated cyclin Negative GeneticPMID:22681890
imp2contractile ring protein Imp2 Synthetic Growth DefectPMID:19139265
spg1GTPase Spg1 Synthetic LethalityPMID:15857958
Synthetic LethalityPMID:11683392
cdc3profilin Synthetic Growth DefectPMID:23297348
mde4monopolin-like complex subunit Mde4 Phenotypic EnhancementPMID:22264609
Phenotypic Suppression
atg9autophagy associated protein Atg9 Positive GeneticPMID:22681890
alf1ATP-dependent microtubule severing protein (predicted) Negative GeneticPMID:22681890
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Phenotypic EnhancementPMID:22624651
Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
mob1Sid2-Mob1 kinase complex regulatory subunit Mob1 Synthetic LethalityPMID:11683392
scs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
klp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
tma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
rad2414-3-3 protein Rad24 Phenotypic EnhancementPMID:18385517
hos2histone deacetylase (class I) Hos2 Phenotypic EnhancementPMID:22559741
SPAC9G1.05actin cortical patch component Aip1 (predicted) Phenotypic EnhancementPMID:21931816
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
SPBC1348.07S. pombe specific DUF999 protein family 6 Positive GeneticPMID:22681890
snt2Lid2 complex subunit Snt2 Negative GeneticPMID:22681890
SPAC1805.14sequence orphan Negative GeneticPMID:22681890
mug80cyclin Clg1 (predicted) Negative GeneticPMID:22681890
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
cdc25M phase inducer phosphatase Cdc25 Synthetic LethalityPMID:15128870
Phenotypic EnhancementPMID:15265986
Phenotypic EnhancementPMID:22665807
cdc15extended Fer/CIP4 (EFC) domain protein Cdc15 Synthetic Growth DefectPMID:20603077
Synthetic Growth DefectPMID:15265986
Synthetic LethalityPMID:19139265
sid4SIN component scaffold protein Sid4 Synthetic LethalityPMID:11683392
Synthetic LethalityPMID:15857958
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Phenotypic SuppressionPMID:15537703
Phenotypic Enhancement
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
rpl200160S ribosomal protein L20a (predicted) Negative GeneticPMID:22681890
ppa2serine/threonine protein phosphatase Ppa2 Phenotypic EnhancementPMID:22624651
Negative GeneticPMID:22681890
myo2myosin II heavy chain Synthetic Growth DefectPMID:15265986
pht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
far10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:23297348
ubp16ubiquitin C-terminal hydrolase Ubp16 Negative GeneticPMID:22681890
SPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
SPAC186.05chuman TMEM165 homolog Positive GeneticPMID:22681890
pub1HECT-type ubiquitin-protein ligase E3 Pub1 Synthetic Growth DefectPMID:18418059
cdc4myosin II light chain Synthetic Growth DefectPMID:15265986
rik1silencing protein Rik1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
dnt1nucleolar protein Dnt1 Synthetic RescuePMID:17538026
cdc14SIN component Cdc14 Synthetic Growth DefectPMID:17538026
Synthetic LethalityPMID:11683392
pab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
emc1ER membrane protein complex subunit Emc1 (predicted) Negative GeneticPMID:22681890
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
SPAC105.02cankyrin repeat protein, implicated in meiosis Negative GeneticPMID:22681890
SPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
liz1pantothenate transporter Liz1 Negative GeneticPMID:22681890
swi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:22264609
Phenotypic Suppression
gcn2eIF2 alpha kinase Gcn2 Negative GeneticPMID:22681890
rad21mitotic cohesin complex, non-SMC subunit Rad21 (kleisin) Synthetic LethalityPMID:15525536
mal3EB1 family Mal3 Synthetic Growth DefectPMID:18931302
hrp1ATP-dependent DNA helicase Hrp1 Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
apl4AP-1 adaptor complex gamma subunit Apl4 Affinity Capture-MSPMID:23297348
yox1MBF complex negative regulatory component Yox1 Affinity Capture-MSPMID:23297348
gaf1transcription factor Gaf1 Affinity Capture-MSPMID:23297348
fyu1UTP-glucose-1-phosphate uridylyltransferase Fyu1 Affinity Capture-MSPMID:23297348
SPCC1739.01zf-CCCH type zinc finger protein Affinity Capture-MSPMID:23297348
sre2membrane-tethered transcription factor (predicted) Affinity Capture-MSPMID:23297348
sep1forkhead transcription factor Sep1 Biochemical ActivityPMID:23297348
Affinity Capture-Western
Affinity Capture-MS
dlc1dynein light chain Dlc1 Affinity Capture-MSPMID:22065639
Affinity Capture-MSPMID:23297348
pob1Boi family protein Affinity Capture-MSPMID:23297348
dna2DNA replication endonuclease-helicase Dna2 Affinity Capture-MSPMID:23297348
ent1epsin Affinity Capture-MSPMID:23297348
rpl3960S ribosomal protein L39 Affinity Capture-MSPMID:23297348
myo1myosin type I Affinity Capture-MSPMID:23297348
mae2malic enzyme, malate dehydrogenase (oxaloacetate decarboxylating), Mae2 Affinity Capture-MSPMID:23297348
dis2serine/threonine protein phosphatase PP1 Affinity Capture-MSPMID:23297348
cdc11SIN component scaffold protein, centriolin ortholog Cdc11 Affinity Capture-WesternPMID:23297348
Biochemical Activity
Affinity Capture-MS
sle1eisosome assembly protein Seg1 Affinity Capture-MSPMID:23297348
rad2514-3-3 protein Rad25 Affinity Capture-MSPMID:23297348
rng2IQGAP Affinity Capture-MSPMID:23297348
SPAC18G6.05ctranslation elongation regulator Gcn1 (predicted) Affinity Capture-MSPMID:23297348
cdc2cyclin-dependent protein kinase Cdk1/Cdc2 Biochemical ActivityPMID:16950131
Biochemical ActivityPMID:22918952
cdc10MBF transcription factor complex subunit Cdc10 Affinity Capture-MSPMID:23297348
Biochemical Activity
Affinity Capture-Western
rpt519S proteasome regulatory subunit Rpt5 (predicted) Affinity Capture-MSPMID:23297348
sfc4transcription factor TFIIIC complex subunit Sfc4 Affinity Capture-MSPMID:23297348
ark1aurora-B kinase Ark1 Affinity Capture-WesternPMID:15525536
csm1chromosome segregation protein Csm1/Pcs1 Affinity Capture-MSPMID:23297348
SPBC776.08cNrap (predicted) Affinity Capture-MSPMID:23297348
SPBC32H8.05conserved fungal protein Affinity Capture-MSPMID:23297348
klp5kinesin-like protein Klp5 Affinity Capture-MSPMID:23297348
nbl1Borealin homolog Nbl1 Affinity Capture-MSPMID:23297348
atp2F1-ATPase beta subunit Atp2 Affinity Capture-MSPMID:23297348
SPCC132.01cnuclear export mediator factor NEMF Affinity Capture-MSPMID:23297348
SPBC4F6.14RNA-binding protein (predicted) Affinity Capture-MSPMID:23297348
csx1RNA-binding protein Csx1 Affinity Capture-MSPMID:23297348
SPCC4G3.13cCUE domain protein Cue1/4 family involved in ER associated protein catabolism (predicted) Affinity Capture-MSPMID:23297348
bag101BAG family molecular chaperone regulator Bag101 (predicted) Affinity Capture-MSPMID:23297348
arf1ADP-ribosylation factor, Arf family Arf1 Affinity Capture-MSPMID:23297348
mbx1MADS-box transcription factor Mbx1 Reconstituted ComplexPMID:21098641
Biochemical Activity
Affinity Capture-MS
Two-hybrid
Affinity Capture-Western
Affinity Capture-MSPMID:23297348
shk1PAK-related kinase Shk1 Affinity Capture-MSPMID:23297348
Biochemical Activity
Affinity Capture-Western
SPCC70.03cproline dehydrogenase (predicted) Affinity Capture-MSPMID:23297348
bir1survivin, Bir1 Affinity Capture-MSPMID:23297348
exo2exonuclease II Exo2 Affinity Capture-MSPMID:23297348
prh1ATP-dependent RNA helicase Prh1 (predicted) Affinity Capture-MSPMID:23297348
rad2414-3-3 protein Rad24 Affinity Capture-MSPMID:23394829
Co-localizationPMID:16085489
Reconstituted Complex
Affinity Capture-MSPMID:23297348
Affinity Capture-WesternPMID:22918952
SPAC27D7.02cGRIP domain protein (predicted) Affinity Capture-MSPMID:23297348
SPBC1703.13cmitochondrial inorganic phosphate transporter (predicted) Affinity Capture-MSPMID:23297348
ath1ataxin-2 homolog Affinity Capture-MSPMID:23297348
bub3mitotic spindle checkpoint protein Bub3 Affinity Capture-MSPMID:23297348
cdc15extended Fer/CIP4 (EFC) domain protein Cdc15 Affinity Capture-MSPMID:23297348
spc19DASH complex subunit Spc19 Affinity Capture-MSPMID:23297348
SPBC1A4.07cU3 snoRNP-associated protein Sof1 (predicted) Affinity Capture-MSPMID:23297348
mrt4mRNA turnover and ribosome assembly protein Mrt4 (predicted) Affinity Capture-MSPMID:23297348
cds1replication checkpoint kinase Cds1 Affinity Capture-WesternPMID:18385517
ubp16ubiquitin C-terminal hydrolase Ubp16 Affinity Capture-MSPMID:23297348
sal3karyopherin Sal3 Affinity Capture-WesternPMID:23297348
Affinity Capture-MS
cdc4myosin II light chain Affinity Capture-MSPMID:23297348
sap1switch-activating protein Sap1 Affinity Capture-WesternPMID:23297348
Affinity Capture-MS
Biochemical Activity
pic1INCENP, Pic1 Affinity Capture-MSPMID:23297348
lys3saccharopine dehydrogenase Lys3 Affinity Capture-MSPMID:23297348
mmb1mitochondria microtubule binder Mmb1 Affinity Capture-MSPMID:23297348
alp14TOG ortholog Alp14 Affinity Capture-MSPMID:23297348
duo1DASH complex subunit Duo1 Affinity Capture-MSPMID:23297348
sid1PAK-related GC kinase Sid1 Co-localizationPMID:11448769
cta4P-type ATPase, calcium transporting Cta4 Affinity Capture-MSPMID:23297348
mid1medial ring protein Mid1 Affinity Capture-MSPMID:23297348
scw1RNA-binding protein Scw1 Affinity Capture-MSPMID:23297348
cyk3cytokinesis protein Cyk3 (predicted) Affinity Capture-MSPMID:23297348
SPAC27E2.03cObg-Like ATPase (predicted) Affinity Capture-MSPMID:23297348
rbp28RNA-binding protein Rbp28 Affinity Capture-MSPMID:23297348
SPCC14G10.04sequence orphan Affinity Capture-MSPMID:23297348
rnp24RNA-binding protein Rnp24 Affinity Capture-MSPMID:23297348
sfc3transcription factor TFIIIC complex B box binding subunit Sfc3 Affinity Capture-MSPMID:23297348
rpb2RNA polymerase II complex subunit Rpb2 Affinity Capture-MSPMID:23297348
has1ATP-dependent RNA helicase Has1 (predicted) Affinity Capture-MSPMID:23297348
sts5RNB-like protein Affinity Capture-MSPMID:23297348
pmk1MAP kinase Pmk1 Biochemical ActivityPMID:22918952
SPCC1183.07U3 snoRNP-associated protein Rrp5 (predicted) Affinity Capture-MSPMID:23297348
SPBC83.15ribosome biogenesis protein Nsa1 (predicted) Affinity Capture-MSPMID:23297348
gpm1monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1 Affinity Capture-MSPMID:23297348
SPBP35G2.14RNA-binding protein Affinity Capture-MSPMID:23297348
pub2HECT-type ubiquitin-protein ligase Pub2 Reconstituted ComplexPMID:18418059
Affinity Capture-Western
nop12RNA-binding protein Nop12 (predicted) Affinity Capture-MSPMID:23297348
upf1ATP-dependent RNA helicase Upf1 Affinity Capture-MSPMID:23297348
rpt619S proteasome regulatory subunit Rpt6 (predicted) Affinity Capture-MSPMID:23297348
rga6Rho-type GTPase activating protein Rga6 (predicted) Affinity Capture-MSPMID:23297348
SPAC22H10.11cTOR signaling pathway transcriptional corepressor Crf1 (predicted) Affinity Capture-MSPMID:23297348
tgs1rRNA methyltransferase Tgs1 (predicted) Affinity Capture-MSPMID:23297348
SPAC9G1.10cinositol polyphosphate phosphatase (predicted) Affinity Capture-MSPMID:23297348
nrm1negative regulator of MBF Affinity Capture-WesternPMID:23297348
Biochemical Activity
Affinity Capture-MS
man1LEM domain protein Man1, Sad1 interacting factor (predicted) Affinity Capture-MSPMID:23297348
klp9kinesin-like protein Klp9 Affinity Capture-MSPMID:23297348
myp2myosin II heavy chain Myo3 Affinity Capture-MSPMID:23297348
SPCC1682.09cmitochondrial guanine nucleotide transporter (predicted) Affinity Capture-MSPMID:23297348
res2MBF transcription factor complex subunit Res2 Affinity Capture-MSPMID:23297348
mug174meiotically upregulated gene Mug174 Affinity Capture-MSPMID:23297348
SPAC31A2.12arrestin/PY protein 1 (predicted) Affinity Capture-MSPMID:23297348
SPAC9E9.09caldehyde dehydrogenase (predicted) Affinity Capture-MSPMID:23297348
kin1microtubule affinity-regulating kinase Kin1 Affinity Capture-MSPMID:23297348
SPCP1E11.08ribosome biogenesis protein Nsa2 (predicted) Affinity Capture-MSPMID:23297348
abp1cofilin/tropomyosin family, drebrin ortholog Abp1 Affinity Capture-MSPMID:23297348
blt1Blt1 Affinity Capture-MSPMID:23297348
mde4monopolin-like complex subunit Mde4 Affinity Capture-WesternPMID:19523829
Biochemical Activity
Affinity Capture-MS
Affinity Capture-MSPMID:23297348
pal1membrane associated protein Pal1 Affinity Capture-MSPMID:23297348
SPBC16H5.08cribosome biogenesis ATPase, Arb family ABCF2-like (predicted) Affinity Capture-MSPMID:23297348
rgf3RhoGEF Rgf3 Affinity Capture-MSPMID:23297348
tif6translation initiation factor eIF6 Affinity Capture-MSPMID:23297348
bub1serine/threonine protein kinase Bub1 Affinity Capture-MSPMID:23297348
clc1clathrin light chain Affinity Capture-MSPMID:23297348
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Affinity Capture-MSPMID:23297348
sfc1transcription factor TFIIIC complex A box associated subunit Sfc1 Affinity Capture-MSPMID:23297348
mts419S proteasome regulatory subunit Mts4 Affinity Capture-MSPMID:23297348
SPAC17H9.04cRNA-binding protein Affinity Capture-MSPMID:23297348
sfc9transcription factor TFIIIC complex subunit Sfc9 (predicted) Affinity Capture-MSPMID:23297348
vps5retromer complex subunit Vps5 Affinity Capture-MSPMID:23297348
ipp1inorganic pyrophosphatase (predicted) Affinity Capture-MSPMID:23297348
klp6kinesin-like protein Klp6 Biochemical ActivityPMID:23297348
Affinity Capture-Western
Affinity Capture-MS
SPCC1827.05cnucleolar RNA-binding protein NIFK (predicted) Affinity Capture-MSPMID:23297348
cdc25M phase inducer phosphatase Cdc25 Affinity Capture-WesternPMID:15128870
Two-hybridPMID:17538026
Affinity Capture-MSPMID:23297348
Affinity Capture-WesternPMID:14765109
not1CCR4-Not complex subunit Not1 (predicted) Affinity Capture-MSPMID:23297348
bgs41,3-beta-glucan synthase subunit Bgs4 Affinity Capture-MSPMID:23297348
ade9C-1-tetrahydrofolatesynthase/methylenetetrahydrof olatedehydrogenase/methylenetetrahydrofolatecyclohydrolase/ formyltetrahydrofolatesynthetase (predicted) Affinity Capture-MSPMID:23297348
SPAC6F6.03cribosome export GTPase (predicted) Affinity Capture-MSPMID:23297348
nsk1Clp1-interacting protein Nsk1 Biochemical ActivityPMID:22065639
Affinity Capture-MS
Affinity Capture-MSPMID:23297348
fta5cell surface glycoprotein Affinity Capture-MSPMID:23297348
SPBC646.07cenoyl reductase (predicted) Affinity Capture-MSPMID:23297348
dnt1nucleolar protein Dnt1 Two-hybridPMID:17538026
SPBC8D2.18cadenosylhomocysteinase (predicted) Affinity Capture-MSPMID:23297348
gua1IMP dehydrogenase Gua1 (predicted) Affinity Capture-MSPMID:23297348
utp10U3 snoRNP-associated protein Utp10 (predicted) Affinity Capture-MSPMID:23297348
res1MBF transcription factor complex subunit Res1 Affinity Capture-MSPMID:23297348
Biochemical Activity
Affinity Capture-Western
SPBPJ4664.04coatomer alpha subunit (predicted) Affinity Capture-MSPMID:23297348
SPAC8F11.04U3 snoRNP-associated protein Cic1/Utp30 family (predicted) Affinity Capture-MSPMID:23297348
mrpl9mitochondrial ribosomal protein subunit L9 (predicted) Affinity Capture-MSPMID:23297348
grs1mitochondrial and cytoplasmic glycine-tRNA ligase Grs1 (predicted) Affinity Capture-MSPMID:23297348
External References
Database Identifier Description
NBRP SPAC1782.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1782.09c Retrieval of eukaryotic orthologs
BioGrid SPAC1782.09c BioGRID Interaction Datasets
Bähler Lab SPAC1782.09c Cell Cycle Expression Profile
Bähler Lab SPAC1782.09c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1782.09c Pheromone response/mating expression profiles
Bähler Lab SPAC1782.09c Environmental stress expression profiles
Bähler Lab SPAC1782.09c Bähler Lab Transcriptome Viewer
Cyclebase SPAC1782.09c Cell Cycle Data
PInt SPAC1782.09c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC1782.09c Entrez Gene
WikiGene2542358Cdc14-related protein phosphatase Clp1/Flp1
Uniprot_genenameCLP1
EntrezGene2542358Cdc14-related protein phosphatase Clp1/Flp1
SPD / RIKEN45/45E07Orfeome Localization Data
UniProtKB/SwissProtQ9P7H1Tyrosine-protein phosphatase CDC14 homolog
ModBaseQ9P7H1Database of comparative protein structure models
Pfam Protein DomainsQ9P7H1Pfam Domain Arrangement
RefSeq PeptideNP_594716Cdc14-related protein phosphatase Clp1/Flp1
RefSeq mRNANM_001020143972h- Cdc14-related protein phosphatase Clp1/Flp1 (clp1), mRNA
European Nucleotide ArchiveCAB76271ENA Protein Mapping
UniParcUPI000012AA18UniProt Archive

Literature for clp1

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013