pnu1 (SPAC17C9.08)

Synonyms nuc1, end1 ChromosomeI
Productmitochondrial endodeoxyribonuclease Pnu1 Gene Start4486171
Feature Typeprotein coding Gene End4484695
Name Description CDS Start4485994
Characterisation Statuspublished CDS End4484835

Ensembl Gene Location
cut8 SPAC17C9.12 SPAC17C9.11c stm1 tim13 > pnu1 < alg8 sam50 pmc3 tif471
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
144861714485713
244855964485350
344852744484695

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF01223 Pfam DNA/RNA non-specific endonuclease 79 290 197.6 1
54060 Superfamily 60 311 231.7 1
SM00477 Smart Extracellular Endonuclease, subunit A 78 291 406.9 1
SM00892 Smart DNA/RNA non-specific endonuclease 77 291 296.3 1
TMHMM tmhmm Double transmembrane domain 9 27 0.9472 1312
PS01070 scanprosite DNA/RNA non-specific endonuclease 139 147 1
SIGNALP_EUK Signalp 1 19 0 456

Protein Properties

Ave. residue weight 113.13 Da
Charge 9.00
Isoelectric point 9.14
Molecular weight 36.43 kDa
Number of residues 322
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000124viableTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000124

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0006308DNA catabolic processISS UniProtKB:P08466GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006308
GO:0006310DNA recombinationISS UniProtKB:P08466GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006310
GO:0006401RNA catabolic processIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006401
GO:0006995cellular response to nitrogen starvationIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0006995

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0005739mitochondrionIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005739
GO:0005743mitochondrial inner membraneISS UniProtKB:P08466GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005743

Molecular Function
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0004518nuclease activityIMPTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004518
GO:0004520endodeoxyribonuclease activityISS UniProtKB:P08466GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004520
GO:0004529exodeoxyribonuclease activityISS UniProtKB:P08466GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0004529

Warning

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DescriptionSourceAll Genes
gene structure updated Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Species Distribution

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DescriptionSourceAll Genes
conserved in BacteriaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000086
predominantly uniformly single copy (one to one)Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000104
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
dsc2UBA domain protein Ucp14 Negative Genetic
dsc1ubiquitin-protein ligase E3 (predicted) Negative Genetic


External References

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Database Identifier Description
NBRP SPAC17C9.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC17C9.08 Retrieval of eukaryotic orthologs
BioGrid SPAC17C9.08 BioGRID Interaction Datasets
Bähler Lab SPAC17C9.08 Cell Cycle Expression Profile
Bähler Lab SPAC17C9.08 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC17C9.08 Pheromone response/mating expression profiles
Bähler Lab SPAC17C9.08 Environmental stress expression profiles
Bähler Lab SPAC17C9.08 Bähler Lab Transcriptome Viewer
Cyclebase SPAC17C9.08 Cell Cycle Data
Entrez Gene SPAC17C9.08 Link to Entrez Gene
SPD / RIKEN44/44A10Orfeome Localization Data
UniProtKB/SwissProtQ10480Nuclease 1, mitochondrial
ArrayExpressQ10480Link to ArrayExpress
RefSeq PeptideNP_594598mitochondrial endodeoxyribonuclease Pnu1
RefSeq mRNANM_001020026972h- mitochondrial endodeoxyribonuclease Pnu1 (pnu1), mRNA
European Nucleotide ArchiveAB050780ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveBAB20882ENA Protein Mapping
European Nucleotide ArchiveCAA97354ENA Protein Mapping
UniParcUPI00001687D6UniProt Archive

Literature for pnu1

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Search: UK PMC or PubMed