tco1 (SPAC17G6.02c)

Gene Standard Nametco1 ChromosomeI
Systematic IDSPAC17G6.02c Gene Start3590624
Synonyms Gene End3588615
ProductRTA1-like protein Gene Length2010
Feature Typeprotein coding CDS Start3589949
Name Description CDS End3588975
Characterisation Statuspublished CDS Length975

Ensembl Gene Location
  1. rrp1
  2. rad25
  3. SPNCRNA.919
  4. SPNCRNA.920
  5. SPAC17A2.14
  6. SPNCRNA.600
  7. tco1
  8. SPAC17G6.03
  9. SPATRNALEU.03
  10. SPNCRNA.226
  11. cpp1
  12. bro1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopytco1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0004012phospholipid-translocating ATPase activityISOSGD:S000005575GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0034599cellular response to oxidative stressNASGO_REF:0000001
GO:0045332phospholipid translocationISOSGD:S000005575GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0005886plasma membraneISSUniProtKB:P40100GO_REF:0000001
GO:0016021integral to membraneIEAUniProtKB:KW-0812GO_REF:0000037
GO:0032153cell division siteIDAPMID:16823372
GO:0051286cell tipIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
135906243588615

References

Region Start End Reference
three_prime_UTR35889743588615PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF04479 IPR007568 Pfam RTA-like protein 43 272 1
TMhelix TMHMM 71 93 955
TMhelix TMHMM 206 223 955
TMhelix TMHMM 10 32 955
TMhelix TMHMM 155 177 955
TMhelix TMHMM 238 260 955
TMhelix TMHMM 113 135 955
TMhelix TMHMM 39 56 955
PTHR31461 hmmpanther 7 255 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0001809signal_anchor
SO:0001812transmembrane_helix

Protein Properties

Ave. residue weight 110.90 Da
Charge -2.00
Isoelectric point 6.08
Molecular weight 35.93 kDa
Number of residues 324
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
alternative transcripts PMID:18276645
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide3.7PMID:23101633
expression microarray evidenceincreasedPMID:22840777
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2.2PMID:23101633
Warning
DescriptionQualifierReference
in the current viewer tco1 gene is hidden behind SPNCRNA.600
Species Distribution
DescriptionQualifierReference
conserved in fungi
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
shf1small histone ubiquitination factor Shf1 Positive GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Positive GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
atp15F0-ATPase epsilon subunit (predicted) Positive GeneticPMID:22681890
bst1GPI inositol deacylase Bst1 (predicted) Negative GeneticPMID:22681890
SPAC1610.02cmitochondrial ribosomal protein subunit L1 (predicted) Positive GeneticPMID:22681890
SPBC1861.05pseudouridine-metabolizing bifunctional protein (predicted) Positive GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:21504829
SPBC13E7.03cRNA hairpin binding protein (predicted) Positive GeneticPMID:22681890
rpl200160S ribosomal protein L20a (predicted) Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC17G6.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC17G6.02c Retrieval of eukaryotic orthologs
BioGrid SPAC17G6.02c BioGRID Interaction Datasets
Bähler Lab SPAC17G6.02c Cell Cycle Expression Profile
Bähler Lab SPAC17G6.02c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC17G6.02c Pheromone response/mating expression profiles
Bähler Lab SPAC17G6.02c Environmental stress expression profiles
Bähler Lab SPAC17G6.02c Bähler Lab Transcriptome Viewer
Cyclebase SPAC17G6.02c Cell Cycle Data
PInt SPAC17G6.02c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC17G6.02c Entrez Gene
SPD / RIKEN13/13H11Orfeome Localization Data
WikiGene2542288RTA1-like protein
EntrezGene2542288RTA1-like protein
UniProtKB/SwissProtO13780Uncharacterized protein C17G6.02c
ModBaseO13780Database of comparative protein structure models
Pfam Protein DomainsO13780Pfam Domain Arrangement
RefSeq PeptideNP_594249RTA1-like protein
RefSeq mRNANM_001019672972h- RTA1-like protein (tco1), mRNA
European Nucleotide ArchiveBAA87202ENA Protein Mapping
European Nucleotide ArchiveCAB16213ENA Protein Mapping
SPD / RIKEN13/13H11Orfeome Localization Data

Literature for tco1
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013