yaf9 (SPAC17G8.07)


Gene Standard Nameyaf9 Characterisation Statuspublished
Systematic IDSPAC17G8.07 Feature Typeprotein coding
Synonyms Name Description
ProductYEATS family histone acetyltransferase subunit Yaf9 Product Size217aa, 24.95 kDa
Genomic Location Chromosome I, 2354127-2355211 (1085nt); CDS:2354401-2355054 (654nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
chromatin silencing112
Annotation ExtensionEvidenceWith/FromReference
DNA repair171
Annotation ExtensionEvidenceWith/FromReference
histone acetylation46
Annotation ExtensionEvidenceWith/FromReference
histone exchange23
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
NuA4 histone acetyltransferase complex14
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
Swr1 complex15
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
sensitive to cadmiumyaf9Δ249
sensitive to doxorubicinyaf9Δ93
sensitive to hydroxyureayaf9Δ547
sensitive to salt stressyaf9Δ98
viable vegetative cell populationyaf9Δ3831

Cell Phenotype

Term NameGenotypesCount
abnormal microtubule cytoskeletonyaf9Δ240
abolished activation of bipolar cell growthyaf9Δ13
single microtubule bundleyaf9Δ10
viable curved vegetative cellyaf9Δ70
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2354127..2355211
5' UTR2354127..2354400PMID:21511999
3' UTR2355055..2355211PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03366 Pfam IPR005033 YEATS 38 118 2
PS51037 Prosite Profiles IPR005033 YEATS 13 121 2
PTHR23195 HMMPANTHER IPR005033 YEATS 4 208 2
Coil ncoils Predicted coiled-coil protein (DUF2205) 190 210 1050

View domain organization at Pfam

Term IDTerm NameReferenceCount
PBO:0000297histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Term IDTerm NameReferenceCount
SO:0001080coiled_coil107
qualifier region

Protein Properties

Ave. residue weight 114.96 Da
Charge -7.50
Codon Adaptation Index 0.48
Isoelectric point 5.05
Molecular weight 24.95 kDa
Number of residues 217
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for yaf9 (SPAC17G8.07)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9573during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
6703during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
10087during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
6174during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
5885during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
2459.46during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
5429.13during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.4during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.42during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Misc
DescriptionQualifierReferenceCount
proteome hyperlink PMID:190407209
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3422
conserved in vertebrates3397
conserved in eukaryotes only2504
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC17G8.07 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC17G8.07 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC17G8.07 BioGRID Interaction Datasets
Expression Viewer SPAC17G8.07 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC17G8.07 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC17G8.07 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC17G8.07 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC17G8.07 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC17G8.07 Transcriptome Viewer (Bähler Lab)
GEO SPAC17G8.07 GEO profiles
PInt SPAC17G8.07 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC17G8.07 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC17G8.07 Fission yeast phenotypic data & analysis
Cyclebase SPAC17G8.07.1 Cell Cycle Data
SPD / RIKEN07/07E08Orfeome Localization Data
UniProtKB/SwissProtQ10319Protein AF-9 homolog
ModBaseQ10319Database of comparative protein structure models
STRINGQ10319Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593730YEATS family histone acetyltransferase subunit Yaf9
RefSeq mRNANM_001019161972h- YEATS family histone acetyltransferase subunit Yaf9 (yaf9), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAA93690ENA Protein Mapping
UniParcUPI000013A88DUniProt Archive

Literature for yaf9

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016