yaf9 (SPAC17G8.07)

Gene Standard Nameyaf9 ChromosomeI
Systematic IDSPAC17G8.07 Gene Start2354127
Synonyms Gene End2355211
ProductYEATS family histone acetyltransferase subunit Yaf9 Gene Length1085
Feature Typeprotein coding CDS Start2354401
Name Description CDS End2355054
Characterisation Statuspublished CDS Length654

Ensembl Gene Location
  1. dpb3
  2. new1
  3. arc5
  4. med20
  5. SPAC17G8.06c
  6. yaf9
  7. SPAC17G8.08c
  8. shg1
  9. dma1
  10. imt3
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000096sensitive to cadmiumCell growth assayyaf9delta (deletion)deletionPECO:0000012PMID:18684775
FYPO:0001491viable vegetative cellMicroscopyyaf9delta (deletion)deletionPMID:20473289
GO Biological Process

Ontology Graph

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Term IDTerm NameEvidenceWith/FromReference
GO:0006281DNA repairISOSGD:S000005051GO_REF:0000024
GO:0006342chromatin silencingISOSGD:S000005051GO_REF:0000024
GO:0016573histone acetylationICGO:0035267GO_REF:0000001
GO:0043486histone exchangeISOSGD:S000005051GO_REF:0000024
GO:0071276cellular response to cadmium ionIMPPMID:18684775
GO:0071585detoxification of cadmium ionIMPPMID:18684775
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000812Swr1 complexIDAPMID:19040720
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0035267NuA4 histone acetyltransferase complexIDAPMID:19040720
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
123541272355211

References

Region Start End Reference
three_prime_UTR23550552355211PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03366 IPR005033 Pfam YEATS 38 119 2
PS51037 IPR005033 Prosite Profiles YEATS 13 121 2
Coil ncoils Rabaptin coiled-coil domain 190 211 974
PTHR23195 IPR005033 hmmpanther YEATS 6 208 2

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000297histone foldTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000297

Sequence Ontology

Term IDTerm NameReference
SO:0001080coiled_coil

Protein Properties

Ave. residue weight 114.96 Da
Charge -7.50
Isoelectric point 5.05
Molecular weight 24.95 kDa
Number of residues 217
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide2459.46PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide5429.13PMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.4PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.42PMID:23101633
Misc
DescriptionQualifierReference
proteome hyperlink PMID:19040720
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
rhn1RNA polymerase II transcription termination factor homolog Negative GeneticPMID:18818364
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:18818364
SPAC637.06alpha-1,2-galactosyltransferase (predicted) Positive GeneticPMID:18818364
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:18818364
gfh1gamma tubulin complex subunit Gfh1 Negative GeneticPMID:18818364
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:18818364
puf3RNA-binding protein Puf3 (predicted) Negative GeneticPMID:18818364
ash2Ash2-trithorax family protein Negative GeneticPMID:18818364
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:18818364
set1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
hhf2histone H4 h4.2 Negative GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
mph1dual specificity protein kinase Mph1 Negative GeneticPMID:18818364
clr3histone deacetylase (class II) Clr3 Negative GeneticPMID:18818364
SPCC1919.13cribosome biogenesis protein (predicted) Negative GeneticPMID:18818364
mga2IPT/TIG ankyrin repeat containing transcription regulator of fatty acid biosynthesis (predicted) Negative GeneticPMID:18818364
mug154conserved fungal protein Negative GeneticPMID:18818364
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
spc34DASH complex subunit Spc34 Negative GeneticPMID:18818364
alp16gamma tubulin complex subunit Alp16 Negative GeneticPMID:18818364
SPBC16C6.05mitochondrial translation initiation factor (predicted) Negative GeneticPMID:18818364
med7mediator complex subunit Med7 Negative GeneticPMID:18818364
SPBC1861.07elongin C (predicted) Negative GeneticPMID:18818364
ask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
rhp14XP-A family homolog Rhp14 Negative GeneticPMID:18818364
spf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
bdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:18818364
dad1DASH complex subunit Dad1 Negative GeneticPMID:18818364
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
set11ribosomal protein lysine methyltransferase Set11 Negative GeneticPMID:18818364
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:18818364
mrc1mediator of replication checkpoint 1 Negative GeneticPMID:18818364
ubc6ubiquitin conjugating enzyme Ubc6 (predicted) Positive GeneticPMID:18818364
ppk16serine/threonine protein kinase Ppk16 (predicted) Negative GeneticPMID:18818364
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:18818364
swr1SNF2 family helicase Swr1 Positive GeneticPMID:18818364
SPAC25B8.05tRNA-pseudouridine synthase (predicted) Negative GeneticPMID:18818364
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:18818364
bdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:18818364
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
SPBC36B7.08cnucleosome assembly protein (predicted) Negative GeneticPMID:18818364
set3histone lysine methyltransferase Set3 Negative GeneticPMID:18818364
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
res2MBF transcription factor complex subunit Res2 Positive GeneticPMID:18818364
SPAC328.01ckaryopherin (predicted) Negative GeneticPMID:18818364
bob1prefoldin subunit 5 (predicted) Negative GeneticPMID:18818364
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:18818364
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
ppk30Ark1/Prk1 family protein kinase Ppk30 Positive GeneticPMID:18818364
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:18818364
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:18818364
wis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Negative GeneticPMID:18818364
pom1DYRK family protein kinase Pom1 Negative GeneticPMID:18818364
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Phenotypic EnhancementPMID:19547744
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:18818364
pho24-nitrophenylphosphatase Negative GeneticPMID:18818364
swc5Swr1 complex subunit Swc5 Positive GeneticPMID:18818364
atg18WD repeat protein involved in autophagy Atg18a Negative GeneticPMID:18818364
hif2Set3 complex subunit Hif2 Negative GeneticPMID:18818364
vps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
swc2Swr1 complex complex subunit Swc2 Positive GeneticPMID:18818364
ser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:18818364
not2CCR4-Not complex subunit Not2 (predicted) Negative GeneticPMID:18818364
SPAC824.04WD repeat protein (predicted) Negative GeneticPMID:18818364
nto1histone acetyltransferase complex subunit Nto1 (predicted) Negative GeneticPMID:18818364
cid12poly(A) polymerase Cid12 Positive GeneticPMID:18818364
top1DNA topoisomerase I Negative GeneticPMID:18818364
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:18818364
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:18818364
SPBC31F10.12RNA-binding protein Tma20 (predicted) Negative GeneticPMID:18818364
klp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
tim13TIM22 inner membrane protein import complex subunit Tim13 (predicted) Negative GeneticPMID:18818364
hos2histone deacetylase (class I) Hos2 Negative GeneticPMID:18818364
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Negative GeneticPMID:18818364
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
sec28coatomer epsilon subunit (predicted) Negative GeneticPMID:18818364
mms19Dos2 silencing complex subunit Mms19 Negative GeneticPMID:18818364
not3CCR4-Not complex subunit Not3/5 (predicted) Negative GeneticPMID:18818364
arp6actin-like protein Arp6 Positive GeneticPMID:18818364
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Negative GeneticPMID:18818364
SPCC550.03cSki complex RNA helicase Ski2 (predicted) Negative GeneticPMID:18818364
pht1histone H2A variant H2A.Z, Pht1 Positive GeneticPMID:18818364
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:18818364
hhf1histone H4 h4.1 Negative GeneticPMID:18818364
png2ING family homolog Png2 Negative GeneticPMID:18818364
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
arp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:18818364
mad1mitotic spindle checkpoint protein Mad1 Negative GeneticPMID:18818364
res1MBF transcription factor complex subunit Res1 Phenotypic EnhancementPMID:19547744
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
cay1cactin, spliceosome complex subunit (predicted) Negative GeneticPMID:18818364
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:18818364
hip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
tra2NuA4 complex phosphatidylinositol pseudokinase complex subunit Tra2 Affinity Capture-MSPMID:21642955
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External References
Database Identifier Description
NBRP SPAC17G8.07 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC17G8.07 Retrieval of eukaryotic orthologs
BioGrid SPAC17G8.07 BioGRID Interaction Datasets
Bähler Lab SPAC17G8.07 Cell Cycle Expression Profile
Bähler Lab SPAC17G8.07 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC17G8.07 Pheromone response/mating expression profiles
Bähler Lab SPAC17G8.07 Environmental stress expression profiles
Bähler Lab SPAC17G8.07 Bähler Lab Transcriptome Viewer
Cyclebase SPAC17G8.07 Cell Cycle Data
PInt SPAC17G8.07 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC17G8.07 Entrez Gene
WikiGene2542278YEATS family histone acetyltransferase subunit Yaf9
Uniprot_genenameYAF9
EntrezGene2542278YEATS family histone acetyltransferase subunit Yaf9
SPD / RIKEN07/07E08Orfeome Localization Data
UniProtKB/SwissProtQ10319Protein AF-9 homolog
ModBaseQ10319Database of comparative protein structure models
Pfam Protein DomainsQ10319Pfam Domain Arrangement
RefSeq PeptideNP_593730YEATS family histone acetyltransferase subunit Yaf9
RefSeq mRNANM_001019161972h- YEATS family histone acetyltransferase subunit Yaf9 (yaf9), mRNA
European Nucleotide ArchiveCAA93690ENA Protein Mapping
SPD / RIKEN07/07E08Orfeome Localization Data

Literature for yaf9
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013