psc3 (SPAC17H9.20)

SynonymsSPAC607.01 ChromosomeI
Productmitotic cohesin complex, non-SMC subunit Psc3 Gene Start2036327
Feature Typeprotein coding Gene End2040544
Name Description CDS Start2036403
Characterisation Statuspublished CDS End2039520

Ensembl Gene Location
tom22 mdm10 SPAC17H9.18c cdt2 > psc3 < SPAC607.02c snu13 SPNCRNA.185 SPNCRNA.789 SPAC607.04 rpn9 SPAC607.06c
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
120363272036667
220367132036825
320368642036959
420370082037417
520374682039067
620391162040544

Protein Feature Information
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Protein Features

Ensembl protein image with mapped locations of structural domains
Feature ID Database Description Start End Score All Genes
PF08514 Pfam STAG 160 275 151 2
48371 Superfamily 74 842 51.1 119
PS51425 PROSITE Stromalin conservative domain 297 382 33.168 2

Protein Properties

Ave. residue weight 115.02 Da
Charge -14.00
Isoelectric point 5.20
Molecular weight 110.65 kDa
Number of residues 962
Sequence
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Fission Yeast Phenotype

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Term IDDescriptionSourceAll Genes
FYPO:0000131abnormal mitotic spindle elongationTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000131
FYPO:0000029abnormal chromosome segregationTemporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000029
FYPO:0000049inviable
Temporary processing gif - replaced by AJAX with count of genes annotated with the term FYPO:0000049

Gene Ontology Annotations

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Biological Process
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GO IDTermEvidenceWith/FromSourceAll Genes

Cellular Component
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GO IDTermEvidenceWith/FromSourceAll Genes
GO:0000794condensed nuclear chromosomeIC GO:0030892GO_REF:0000001Temporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0000794
GO:0005634nucleusIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0005634
GO:0030892mitotic cohesin complexIDATemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - PubMed ID replaced by AJAX with the autor year referenceTemporary processing gif - replaced by AJAX with count of genes annotated with the term GO:0030892
TASGO_REF:unpublished

Warning

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DescriptionSourceAll Genes
gene structure updated Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with the citation reference [author (year)]Temporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000070

Protein Family

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DescriptionSourceAll Genes
HEAT repeatTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000328

Species Distribution

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DescriptionSourceAll Genes
conserved in FungiTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000057
conserved in Eukaryotes onlyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000096
conserved in VertebratesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000095
conserved in EukaryotesTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000058
conserved in MetazoaTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000094

Manually Curated Orthologs

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SpeciesGeneDescription

Interactions

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Genetic Interactions from BioGRID

Gene Feature Evidence Source
swi6chromodomain protein Swi6 Synthetic Lethality
Synthetic Lethality
cut9anaphase-promoting complex subunit Cut9 Phenotypic Suppression
bub3mitotic spindle checkpoint protein Bub3 Synthetic Lethality
cut1separase/separin Dosage Lethality

Physical Interactions from BioGRID

Gene Feature Evidence Source
swi6chromodomain protein Swi6 Two-hybrid
Affinity Capture-Western
dfp1Hsk1-Dfp1 kinase complex regulatory subunit Dfp1 Affinity Capture-Western

External References

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Database Identifier Description
NBRP SPAC17H9.20 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC17H9.20 Retrieval of eukaryotic orthologs
BioGrid SPAC17H9.20 BioGRID Interaction Datasets
Bähler Lab SPAC17H9.20 Cell Cycle Expression Profile
Bähler Lab SPAC17H9.20 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC17H9.20 Pheromone response/mating expression profiles
Bähler Lab SPAC17H9.20 Environmental stress expression profiles
Bähler Lab SPAC17H9.20 Bähler Lab Transcriptome Viewer
Cyclebase SPAC17H9.20 Cell Cycle Data
Entrez Gene SPAC17H9.20 Link to Entrez Gene
SPD / RIKEN47/47H04Orfeome Localization Data
UniProtKB/SwissProtO13816Cohesin subunit psc3
ArrayExpressO13816Link to ArrayExpress
RefSeq_mRNA_predictedXM_001713011972h- mitotic cohesin complex, non-SMC subunit Psc3 (psc3), mRNA
RefSeq_peptide_predictedXP_001713063mitotic cohesin complex, non-SMC subunit Psc3
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAJ41421ENA Protein Mapping
UniParcUPI0000D7213CUniProt Archive

Literature for psc3

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Search: UK PMC or PubMed