rps7 (SPAC18G6.14c)


Gene Standard Namerps7 Characterisation Statusbiological role inferred
Systematic IDSPAC18G6.14c Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S7 (predicted) Product Size195aa, 21.95 kDa
Genomic Location Chromosome I, 2242554-2241748 (807nt); CDS:2242523-2241936 (588nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation469
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis337
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
cytosolic small ribosomal subunit64
Annotation ExtensionEvidenceWith/FromReference
nucleolus366
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationrps7Δ1450

Cell Phenotype

Term NameGenotypesCount
inviable sporerps7Δ475
Target Of
OntologyRelationshipGeneProduct
GO substrate of ubp15 ubiquitin C-terminal hydrolase Ubp15
GO substrate of ubp4 ubiquitin C-terminal hydrolase Ubp4
GO substrate of ubp5 ubiquitin C-terminal hydrolase Ubp5
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2242554..2241748
5' UTR2242554..2242524PMID:21511999
3' UTR2241935..2241748AU011818
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01251 Pfam IPR000554 Ribosomal protein S7e 6 188 1
PS00948 Prosite Patterns IPR000554 Ribosomal protein S7e 78 91 1
PTHR11278 HMMPANTHER IPR000554 Ribosomal protein S7e 1 195 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 112.55 Da
Charge 18.00
Codon Adaptation Index 0.72
Isoelectric point 10.85
Molecular weight 21.95 kDa
Number of residues 195
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1675
present during cellular response to thiabendazoleS170
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA S170 PMID:18257517
O-phospho-L-threonine 700
present during cellular response to thiabendazoleT151
present during cellular response to thiabendazoleT146
Annotation ExtensionEvidenceResidueReference
present during cellular response to thiabendazole IDA T146 PMID:18257517
present during cellular response to thiabendazole IDA T151 PMID:18257517
phosphorylated residue 1930
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
ubiquitinylated lysineK6, K9, K70, K85, K86, K177 512
Annotation ExtensionEvidenceResidueReference
IDA PMID:26412298
mass spectrometry evidence K6 PMID:26412298
mass spectrometry evidence K9 PMID:26412298
mass spectrometry evidence K70 PMID:26412298
mass spectrometry evidence K85 PMID:26412298
mass spectrometry evidence K86 PMID:26412298
mass spectrometry evidence K177 PMID:26412298
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for rps7 (SPAC18G6.14c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
378779during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
402338during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
408456during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
428490during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
149704.21during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
362010during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
68126.76during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
130during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
11during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3422
conserved in vertebrates3397
conserved in eukaryotes only2504
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load gene that interact physically with SPAC18G6.14c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bycbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
affinity captured byred5human ZC3H3 homolog Affinity Capture-MSPMID:24713849
affinity captured bymtl1TRAMP complex ATP-dependent RNA helicase (predicted) Affinity Capture-MSPMID:24713849
Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPAC18G6.14c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
rescued bybyr2MAP kinase kinase kinase Byr2 Phenotypic SuppressionPMID:1515675
rescued byras1GTPase Ras1 Phenotypic SuppressionPMID:1515675
negative genetic interaction withrga3Rho-type GTPase activating protein Rga3 Negative GeneticPMID:22681890
negative genetic interaction withpac10prefoldin subunit 3 Pac10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withatg17autophagy associated protein kinase activator Atg17 Negative GeneticPMID:22681890
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
negative genetic interaction withmmb1mitochondrial microtubule binder Mmb1 Negative GeneticPMID:22681890
negative genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withmid1medial ring protein Mid1 Negative GeneticPMID:22681890
negative genetic interaction withSPCC737.07cDNA polymerase alpha-associated DNA helicase A (predicted) Negative GeneticPMID:22681890
negative genetic interaction withams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
negative genetic interaction withSPBC713.07cvacuolar polyphosphatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnop10snoRNP pseudouridylase box H/ACA snoRNP complex protein (predicted) Negative GeneticPMID:22681890
positive genetic interaction withbut1neddylation pathway protein But1 Positive GeneticPMID:22681890
positive genetic interaction withsif1Sad1 interacting factor 1 Positive GeneticPMID:22681890
positive genetic interaction withSPCC16C4.106-phosphogluconolactonase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withatb2tubulin alpha 2 Positive GeneticPMID:22681890
positive genetic interaction withhus1checkpoint clamp complex protein Hus1 Positive GeneticPMID:22681890
positive genetic interaction withSPCPB16A4.02cconserved fungal protein Positive GeneticPMID:22681890
positive genetic interaction withmph1dual specificity protein kinase Mph1 Positive GeneticPMID:22681890
positive genetic interaction withdad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
positive genetic interaction withsts5RNB-like protein Positive GeneticPMID:22681890
positive genetic interaction withvps35retromer complex subunit Vps35 Positive GeneticPMID:22681890
positive genetic interaction withksg1serine/threonine protein kinase Ksg1 Positive GeneticPMID:22681890
positive genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Positive GeneticPMID:22681890
positive genetic interaction withcyp3cyclophilin family peptidyl-prolyl cis- trans isomerase Cyp3 Positive GeneticPMID:22681890
overexpression rescuescdc16two-component GAP Cdc16 Dosage RescuePMID:10924454
External References
Database Identifier Description
NBRP SPAC18G6.14c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC18G6.14c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC18G6.14c BioGRID Interaction Datasets
Expression Viewer SPAC18G6.14c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC18G6.14c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC18G6.14c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC18G6.14c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC18G6.14c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC18G6.14c Transcriptome Viewer (Bähler Lab)
GEO SPAC18G6.14c GEO profiles
PInt SPAC18G6.14c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC18G6.14c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC18G6.14c Fission yeast phenotypic data & analysis
Cyclebase SPAC18G6.14c.1 Cell Cycle Data
SPD / RIKEN06/06D07Orfeome Localization Data
UniProtKB/SwissProtQ1010140S ribosomal protein S7
ModBaseQ10101Database of comparative protein structure models
STRINGQ10101Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59367740S ribosomal protein S7
RefSeq mRNANM_001019109972h- 40S ribosomal protein S7 (rps7), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAA92393ENA Protein Mapping
UniParcUPI000013511DUniProt Archive

Literature for rps7

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016