srp14 (SPAC19B12.09)


Gene Standard Namesrp14 Characterisation Statuspublished
Systematic IDSPAC19B12.09 Feature Typeprotein coding
Synonyms Name Description
Productsignal recognition particle subunit Srp14 Product Size106aa, 11.72 kDa
Genomic Location Chromosome I, 4900282-4901134 (853nt); CDS:4900565-4900977 (413nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003723RNA bindingIEAUniProtKB-KW:KW-0694GO_REF:0000037646
GO:0030942endoplasmic reticulum signal peptide bindingIEAIPR003210GO_REF:00000022
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0006617SRP-dependent cotranslational protein targeting to membrane, signal sequence recognitionISOSGD:S000002250GO_REF:00000243
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005730nucleolusIDAPMID:16823372343
GO:0005634nucleusIDAPMID:168233722740
GO:0005786signal recognition particle, endoplasmic reticulum targetingISOSGD:S000002250GO_REF:00000247
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
149002824900585
249006344900712
349007574901134

UTRs

Region Coordinates Reference
five_prime_UTR4900282..4900564PMID:21511999
three_prime_UTR4900978..4901134PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02290 Pfam IPR003210 Signal recognition particle, SRP14 subunit 3 85 1
PTHR12013 HMMPANTHER IPR003210 Signal recognition particle, SRP14 subunit 1 100 1
3.30.720.10 Gene3D IPR009018 Signal recognition particle, SRP9/SRP14 subunit 2 91 2
SSF54762 SuperFamily IPR009018 Signal recognition particle, SRP9/SRP14 subunit 1 88 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.55 Da
Charge 8.00
Isoelectric point 10.09
Molecular weight 11.72 kDa
Number of residues 106
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
50930during GO:0000080PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
51616during GO:0000084PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
52220during GO:0000085PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
45881during GO:0000087PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
46073during GO:0072690PECO:0000126,
PECO:0000005
single_cellmass spectrometry evidencePMID:24763107
8520.21during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Subunit Composition
DescriptionQualifierReferenceCount
homomeric(2) PMID:1939014746
Experimental Tools
DescriptionQualifierReferenceCount
structure PMID:193901474
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC19B12.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19B12.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19B12.09 BioGRID Interaction Datasets
Expression Viewer SPAC19B12.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19B12.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19B12.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19B12.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19B12.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19B12.09 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC19B12.09 Cell Cycle Data
GEO SPAC19B12.09 GEO profiles
PInt SPAC19B12.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19B12.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19B12.09 Fission yeast phenotypic data & analysis
SPD / RIKEN03/03C03Orfeome Localization Data
UniProtKB/SwissProtQ9P372Signal recognition particle subunit srp14
ModBaseQ9P372Database of comparative protein structure models
STRINGQ9P372Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594772signal recognition particle subunit Srp14
RefSeq mRNANM_001020199972h- signal recognition particle subunit Srp14 (srp14), mRNA
ePDB2W9JThe European PDB
PDB2W9JPDB
PDBsum2W9JPDBsum
European Nucleotide ArchiveCAC00557.1ENA Protein Mapping
UniParcUPI0000069997UniProt Archive

Literature for srp14

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014