srp14 (SPAC19B12.09)


Gene Standard Namesrp14 Characterisation Statuspublished
Systematic IDSPAC19B12.09 Feature Typeprotein coding
Synonyms Name Description
Productsignal recognition particle subunit Srp14 Product Size106aa, 11.72 kDa
Genomic Location Chromosome I, 4900282-4901134 (853nt); CDS:4900565-4900977 (413nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
endoplasmic reticulum signal peptide binding2
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
nucleolus359
Annotation ExtensionEvidenceWith/FromReference
nucleus2695
Annotation ExtensionEvidenceWith/FromReference
signal recognition particle, endoplasmic reticulum targeting7
Annotation ExtensionEvidenceWith/FromReference
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4900282..4900585, 4900634..4900712, 4900757..4901134
Introns4900586..4900633, 4900713..4900756
mRNA4900282..4901134
5' UTR4900282..4900564PMID:21511999
CDS4900565..4900585, 4900634..4900712, 4900757..4900977
3' UTR4900978..4901134PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02290 Pfam IPR003210 Signal recognition particle, SRP14 subunit 3 85 1
PTHR12013 HMMPANTHER IPR003210 Signal recognition particle, SRP14 subunit 1 100 1
3.30.720.10 Gene3D IPR009018 Signal recognition particle, SRP9/SRP14 subunit 2 91 2
SSF54762 SuperFamily IPR009018 Signal recognition particle, SRP9/SRP14 subunit 1 88 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.55 Da
Charge 8.00
Isoelectric point 10.09
Molecular weight 11.72 kDa
Number of residues 106
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
50930during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
51616during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
52220during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
45881during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
8520.21during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
46073during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Subunit Composition
DescriptionQualifierReferenceCount
homomeric(2) PMID:1939014749
Experimental Tools
DescriptionQualifierReferenceCount
structure PMID:193901474
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC19B12.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19B12.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19B12.09 BioGRID Interaction Datasets
Expression Viewer SPAC19B12.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19B12.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19B12.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19B12.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19B12.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19B12.09 Transcriptome Viewer (Bähler Lab)
GEO SPAC19B12.09 GEO profiles
PInt SPAC19B12.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19B12.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19B12.09 Fission yeast phenotypic data & analysis
Cyclebase SPAC19B12.09.1 Cell Cycle Data
SPD / RIKEN03/03C03Orfeome Localization Data
UniProtKB/SwissProtQ9P372Signal recognition particle subunit srp14
ModBaseQ9P372Database of comparative protein structure models
STRINGQ9P372Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594772signal recognition particle subunit Srp14
RefSeq mRNANM_001020199972h- signal recognition particle subunit Srp14 (srp14), mRNA
ePDB2W9JThe European PDB
PDB2W9JPDB
PDBsum2W9JPDBsum
European Nucleotide ArchiveCAC00557.1ENA Protein Mapping
UniParcUPI0000069997UniProt Archive

Literature for srp14

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015