srp14 (SPAC19B12.09)

Gene Standard Namesrp14 Characterisation Statuspublished
Systematic IDSPAC19B12.09 Feature Typeprotein coding
Synonyms Name Description
Productsignal recognition particle subunit Srp14 Product Size106aa, 11.72 kDa
Genomic Location Chromosome I, 4900282-4901134 (853nt); CDS:4900565-4900977 (413nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
endoplasmic reticulum signal peptide binding2
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
signal recognition particle, endoplasmic reticulum targeting7
Annotation ExtensionEvidenceWith/FromReference
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4900282..4900585, 4900634..4900712, 4900757..4901134
Intron4900586..4900633, 4900713..4900756
5' UTR4900282..4900564PMID:21511999
CDS4900565..4900585, 4900634..4900712, 4900757..4900977
3' UTR4900978..4901134PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02290 Pfam IPR003210 Signal recognition particle, SRP14 subunit 3 85 1
3.30.720.10 Gene3D IPR009018 Signal recognition particle, SRP9/SRP14 subunit 2 91 2
SSF54762 SuperFamily IPR009018 Signal recognition particle, SRP9/SRP14 subunit 1 88 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.55 Da
Charge 8.00
Codon Adaptation Index 0.48
Isoelectric point 10.09
Molecular weight 11.72 kDa
Number of residues 106
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for srp14 (SPAC19B12.09)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
50930during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
51616during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
52220during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
45881during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
46073during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
8520.21during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.7during GO:0072690PECO:0000126,
population wideexperimental evidencePMID:23101633
0.45during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Subunit Composition
homomeric(2) PMID:1939014753
Experimental Tools
structure PMID:193901474
Taxonomic Conservation
predominantly single copy (one to one)3087
conserved in fungi4608
conserved in eukaryotes4516
conserved in metazoa3498
conserved in vertebrates3473
conserved in eukaryotes only2525

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC19B12.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19B12.09 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19B12.09 BioGRID Interaction Datasets
Expression Viewer SPAC19B12.09 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19B12.09 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19B12.09 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19B12.09 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19B12.09 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19B12.09 Transcriptome Viewer (Bähler Lab)
GEO SPAC19B12.09 GEO profiles
PInt SPAC19B12.09 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19B12.09 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19B12.09 Fission yeast phenotypic data & analysis
Cyclebase SPAC19B12.09.1 Cell Cycle Data
SPD / RIKEN03/03C03Orfeome Localization Data
UniProtKB/SwissProtQ9P372Signal recognition particle subunit srp14
ModBaseQ9P372Database of comparative protein structure models
STRINGQ9P372Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594772signal recognition particle subunit Srp14
RefSeq mRNANM_001020199972h- signal recognition particle subunit Srp14 (srp14), mRNA
ePDB2W9JThe European PDB
European Nucleotide ArchiveCAC00557.1ENA Protein Mapping
UniParcUPI0000069997UniProt Archive

Literature for srp14

Search: Europe PMC or PubMed

Release Version: PomBase:30_62 - 30 Jan 2017