imp3 (SPAC19D5.05c)

Gene Standard Nameimp3 Characterisation Statusbiological role inferred
Systematic IDSPAC19D5.05c Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Imp3 (predicted) Product Size183aa, 21.78 kDa
Genomic Location Chromosome I, 5219613-5218789 (825nt); CDS:5219535-5218899 (637nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
snoRNA binding30
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

ribosome biogenesis

Term NameCount
rRNA processing195
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
Annotation ExtensionEvidenceWith/FromReference
small nuclear ribonucleoprotein complex59
Annotation ExtensionEvidenceWith/FromReference
small nucleolar ribonucleoprotein complex35
Annotation ExtensionEvidenceWith/FromReference
small-subunit processome36
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationimp3Δ1452

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination with normal, unseptated germ tube morphologyimp3Δ237
inviable sporeimp3Δ476
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons5219613..5219517, 5219470..5218962, 5218922..5218789
Intron5219516..5219471, 5218961..5218923
5' UTR5219613..5219536PMID:21511999
CDS5219535..5219517, 5219470..5218962, 5218922..5218899
3' UTR5218898..5218789PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00163 Pfam IPR001912 Ribosomal protein S4/S9, N-terminal 4 63 3
PF01479 Pfam IPR002942 RNA-binding S4 domain 109 153 7
SM00363 SMART IPR002942 RNA-binding S4 domain 109 175 6
PS50889 Prosite Profiles IPR002942 RNA-binding S4 domain 109 175 8
PTHR11831 HMMPANTHER IPR022801 Ribosomal protein S4/S9 1 182 4
PTHR11831:SF1 HMMPANTHER 1 182 1 Gene3D IPR002942 RNA-binding S4 domain 109 175 5
SSF55174 SuperFamily 27 177 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 119.00 Da
Charge 12.50
Codon Adaptation Index 0.49
Isoelectric point 9.93
Molecular weight 21.78 kDa
Number of residues 183
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for imp3 (SPAC19D5.05c)

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10867during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
10091during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
5255.64during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
9972during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
3432.22during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.3during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.53during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3092
conserved in fungi4606
conserved in eukaryotes4516
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2505

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC19D5.05c into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bymtl1TRAMP complex ATP-dependent RNA helicase (predicted) Affinity Capture-MSPMID:24713849
binds activation domain construct withfar8SIP/FAR complex striatin subunit, Far8/Csc3 Two-hybridPMID:26771498
External References
Database Identifier Description
NBRP SPAC19D5.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19D5.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19D5.05c BioGRID Interaction Datasets
Expression Viewer SPAC19D5.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19D5.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19D5.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19D5.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19D5.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19D5.05c Transcriptome Viewer (Bähler Lab)
GEO SPAC19D5.05c GEO profiles
PInt SPAC19D5.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19D5.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19D5.05c Fission yeast phenotypic data & analysis
Cyclebase SPAC19D5.05c.1 Cell Cycle Data
SPD / RIKEN07/07C11Orfeome Localization Data
UniProtKB/SwissProtO13835U3 small nucleolar ribonucleoprotein protein imp3
ModBaseO13835Database of comparative protein structure models
STRINGO13835Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594903U3 snoRNP-associated protein Imp3 (predicted)
RefSeq mRNANM_001020332972h- U3 snoRNP-associated protein Imp3 (predicted) (imp3), mRNA
European Nucleotide ArchiveCAB16715.1ENA Protein Mapping
UniParcUPI0000069918UniProt Archive

Literature for imp3

Search: Europe PMC or PubMed

Release Version: PomBase:30_60 - 12 May 2016