imp3 (SPAC19D5.05c)


Gene Standard Nameimp3 Characterisation Statusbiological_role_inferred
Systematic IDSPAC19D5.05c Feature Typeprotein coding
Synonyms Name Description
ProductU3 snoRNP-associated protein Imp3 (predicted) Product Size183aa, 21.78 kDa
Genomic Location Chromosome I, 5219613-5218789 (825nt); CDS:5219535-5218899 (637nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
snoRNA binding31
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process

GO Slim Terms

ribosome biogenesis


Term NameCount
rRNA processing196
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleolus363
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
small nuclear ribonucleoprotein complex59
Annotation ExtensionEvidenceWith/FromReference
small nucleolar ribonucleoprotein complex35
Annotation ExtensionEvidenceWith/FromReference
small-subunit processome36
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationimp3ΔNull1438

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination with normal, unseptated germ tube morphologyimp3ΔNull237
inviable sporeimp3ΔNull472
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons5219613..5219517, 5219470..5218962, 5218922..5218789
mRNA5219613..5218789
5' UTR5219613..5219536PMID:21511999
CDS5219535..5219517, 5219470..5218962, 5218922..5218899
3' UTR5218898..5218789PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00163 Pfam IPR001912 Ribosomal protein S4/S9, N-terminal 2 108 3
PF01479 Pfam IPR002942 RNA-binding S4 domain 109 152 7
SM00363 SMART IPR002942 RNA-binding S4 domain 109 175 6
PS50889 Prosite Profiles IPR002942 RNA-binding S4 domain 109 175 8
PTHR11831:SF1 HMMPANTHER 2 183 1
PTHR11831 HMMPANTHER IPR022801 Ribosomal protein S4/S9 2 183 4
3.10.290.10 Gene3D IPR002942 RNA-binding S4 domain 109 175 5
SSF55174 SuperFamily 27 177 5

View domain organization at Pfam

Protein Properties

Ave. residue weight 119.00 Da
Charge 12.50
Isoelectric point 9.93
Molecular weight 21.78 kDa
Number of residues 183
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
10867during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
10091during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
9972during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
5255.64during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
3432.22during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.3during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.53during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured bymtl1TRAMP complex ATP-dependent RNA helicase (predicted) Affinity Capture-MSPMID:24713849
External References
Database Identifier Description
NBRP SPAC19D5.05c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19D5.05c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19D5.05c BioGRID Interaction Datasets
Expression Viewer SPAC19D5.05c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19D5.05c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19D5.05c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19D5.05c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19D5.05c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19D5.05c Transcriptome Viewer (Bähler Lab)
GEO SPAC19D5.05c GEO profiles
PInt SPAC19D5.05c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19D5.05c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19D5.05c Fission yeast phenotypic data & analysis
Cyclebase SPAC19D5.05c.1 Cell Cycle Data
SPD / RIKEN07/07C11Orfeome Localization Data
UniProtKB/SwissProtO13835U3 small nucleolar ribonucleoprotein protein imp3
ModBaseO13835Database of comparative protein structure models
STRINGO13835Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594903U3 snoRNP-associated protein Imp3 (predicted)
RefSeq mRNANM_001020332972h- U3 snoRNP-associated protein Imp3 (predicted) (imp3), mRNA
European Nucleotide ArchiveCAB16715.1ENA Protein Mapping
UniParcUPI0000069918UniProt Archive

Literature for imp3

Search: Europe PMC or PubMed

Release Version: PomBase:26_52 - 11 May 2015