scs7 (SPAC19G12.08)


Gene Standard Namescs7 Characterisation Statuspublished
Systematic IDSPAC19G12.08 Feature Typeprotein coding
Synonyms Name Description
Productsphingosine hydroxylase Scs7 Product Size347aa, 40.23 kDa
Genomic Location Chromosome I, 4056794-4058815 (2022nt); CDS:4056958-4058289 (1332nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
iron ion binding23
Annotation ExtensionEvidenceWith/FromReference
sphingosine hydroxylase activity2
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
fatty acid biosynthetic process30
Annotation ExtensionEvidenceWith/FromReference
mannosyl-inositol phosphorylceramide metabolic process5
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
endoplasmic reticulum596
Annotation ExtensionEvidenceWith/FromReference
endoplasmic reticulum membrane205
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
normal growth on trichostatin Ascs7ΔNull113
sensitive to 4-nitroquinoline N-oxidescs7ΔNull159
sensitive to 5-fluorouracilscs7ΔNull271
sensitive to cadmiumscs7ΔNull246
sensitive to camptothecinscs7ΔNull224
sensitive to hydroxyureascs7ΔNull525
sensitive to salt stressscs7ΔNull88
sensitive to sodium butyratescs7ΔNull93
sensitive to valproic acidscs7ΔNull155
viable vegetative cell populationscs7ΔNull3792

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyscs7ΔNull3092
Target Of
OntologyRelationshipGeneProductReference
GO regulated by sre1 sterol regulatory element binding protein, transcription factor Sre1 PMID:16537923
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4056794..4057015, 4057304..4058815
Introns4057016..4057303
mRNA4056794..4058815
5' UTR4056794..4056957SPC10699
CDS4056958..4057015, 4057304..4058289
3' UTR4058290..4058815PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF04116 Pfam IPR006694 Fatty acid hydroxylase 189 311 5
TMhelix TMHMM 217 234 959
TMhelix TMHMM 180 202 959
TMhelix TMHMM 267 289 959
TMhelix TMHMM 241 263 959
TMhelix TMHMM 156 175 959
PTHR12863 HMMPANTHER 3 334 1
PIRSF005149 PIRSF IPR014430 Inositolphosphorylceramide-B hydroxylase 2 345 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 115.94 Da
Charge 10.00
Isoelectric point 7.81
Molecular weight 40.23 kDa
Number of residues 347
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
31679during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
34999during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
33472during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
31008during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
30476during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
19929.07during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
2496.23during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
15during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byhhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
affinity captured byhhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withabo2ATPase with bromodomain protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withair1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:18818364
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
negative genetic interaction withalp14TOG/XMAP14 family protein Alp14 Negative GeneticPMID:18818364
negative genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:18818364
negative genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Negative GeneticPMID:22681890
positive genetic interaction withapn2AP-endonuclease Apn2 Positive GeneticPMID:18818364
positive genetic interaction witharp6actin-like protein Arp6 Positive GeneticPMID:18818364
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:18818364
negative genetic interaction witharp8actin-like protein, Ino80 complex subunit Arp8 Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:18818364
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
positive genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withaut12autophagy associated protein Aut12 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withbdf2BET family double bromodomain protein Bdf2 Positive GeneticPMID:18818364
negative genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:18818364
negative genetic interaction withbyr2MAP kinase kinase kinase Byr2 Negative GeneticPMID:18818364
positive genetic interaction withcaf1CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Positive GeneticPMID:18818364
positive genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withcdk9P-TEFb-associated cyclin-dependent protein kinase Cdk9 Negative GeneticPMID:18818364
negative genetic interaction withcdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
positive genetic interaction withcho1phosphatidyl-N-methylethanolamine N-methyltransferase (predicted) Positive GeneticPMID:18818364
negative genetic interaction withchp1chromodomain protein Chp1 Negative GeneticPMID:22681890
negative genetic interaction withcia1histone chaperone Cia1 Negative GeneticPMID:18818364
positive genetic interaction withckb2CK2 family regulatory subunit Ckb2 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withclp1Cdc14-related protein phosphatase Clp1/Flp1 Negative GeneticPMID:22681890
negative genetic interaction withclr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:18818364
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:18818364
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:18818364
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
negative genetic interaction withcsn2COP9/signalosome complex subunit Csn2 Negative GeneticPMID:22681890
negative genetic interaction withcti6histone deacetylase complex subunit Cti6 Negative GeneticPMID:22681890
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:18818364
negative genetic interaction withdad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
positive genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Positive GeneticPMID:18818364
negative genetic interaction withdcr1dicer Negative GeneticPMID:18818364
negative genetic interaction withdcr1dicer Negative GeneticPMID:22681890
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:18818364
positive genetic interaction withdnm1mitochindrial dynamin family GTPase Dnm1 Positive GeneticPMID:18818364
positive genetic interaction withdsc1Golgi Dsc E3 ligase complex subunit Dsc1 Positive GeneticPMID:21504829
positive genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Positive GeneticPMID:21504829
positive genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Positive GeneticPMID:22681890
positive genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
positive genetic interaction withdsc3Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:22681890
positive genetic interaction withdsc4Golgi Dsc E3 ligase complex subunit Dsc3 Positive GeneticPMID:21504829
positive genetic interaction withdsk1SR protein-specific kinase Dsk1 Positive GeneticPMID:18818364
negative genetic interaction withebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction witheif21translation initiation factor eIF2A (predicted) Positive GeneticPMID:18818364
negative genetic interaction withelp1elongator subunit Elp1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withelp4elongator complex subunit Elp4 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withelp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction witheme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
positive genetic interaction withepe1Jmjc domain chromatin associated protein Epe1 Positive GeneticPMID:18818364
positive genetic interaction witherg5C-22 sterol desaturase Erg5 Positive GeneticPMID:18818364
positive genetic interaction withexo1exonuclease I Exo1 Positive GeneticPMID:18818364
negative genetic interaction withfar10SIP/FAR complex FHA domain subunit Far10/Csc1 Negative GeneticPMID:22681890
positive genetic interaction withfbp1fructose-1,6-bisphosphatase Fbp1 Positive GeneticPMID:18818364
negative genetic interaction withfft2SMARCAD1 family ATP-dependent DNA helicase Fft2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withfft2SMARCAD1 family ATP-dependent DNA helicase Fft2 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:18818364
positive genetic interaction withfkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Positive GeneticPMID:18818364
negative genetic interaction withftp105Ubp5 interacting protein Ftp105 Negative GeneticPMID:18818364
negative genetic interaction withget1GET complex subunit Get1 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withgim4prefoldin subunit 2, Gim4(predicted) Positive GeneticPMID:18818364
negative genetic interaction withhhf2histone H4 h4.2 Negative GeneticPMID:18818364
negative genetic interaction withhht2histone H3 h3.2 Negative GeneticPMID:18818364
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
positive genetic interaction withhos2histone deacetylase (class I) Hos2 Positive GeneticPMID:18818364
positive genetic interaction withhrp1ATP-dependent DNA helicase Hrp1 Positive GeneticPMID:18818364
negative genetic interaction withhrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:18818364
negative genetic interaction withhst2Sirtuin family histone deacetylase Hst2 Negative GeneticPMID:18818364
positive genetic interaction withhta1histone H2A alpha Positive GeneticPMID:18818364
negative genetic interaction withies2Ino80 complex subunit Ies2 Negative GeneticPMID:18818364
negative genetic interaction withknd1Cullin-associated NEDD8-dissociated protein Knd1 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:18818364
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:22681890
negative genetic interaction withmde3serine/threonine protein kinase, meiotic Mde3 Negative GeneticPMID:18818364
positive genetic interaction withmed6mediator complex subunit Med6 Positive GeneticPMID:18818364
negative genetic interaction withmeu14sporulation specific PIL domain protein Meu14 Negative GeneticPMID:22681890
negative genetic interaction withmid1medial ring protein Mid1 Negative GeneticPMID:22681890
negative genetic interaction withmik1mitotic inhibitor kinase Mik1 Negative GeneticPMID:22681890
positive genetic interaction withmlh1MutL family protein Mlh1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withmpr1histidine-containing response regulator phosphotransferase Mpr1 Positive GeneticPMID:22681890
positive genetic interaction withmsa1RNA-binding protein Msa1 Positive GeneticPMID:18818364
negative genetic interaction withmsn5karyopherin (predicted) Negative GeneticPMID:18818364
negative genetic interaction withmud1UBA domain protein Mud1 Negative GeneticPMID:18818364
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:18818364
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withmug183histone chaperone Rtt106-like (predicted) Negative GeneticPMID:18818364
positive genetic interaction withnap1nucleosome assembly protein Nap1 Positive GeneticPMID:18818364
positive genetic interaction withngg1SAGA complex subunit Ngg1 Positive GeneticPMID:18818364
positive genetic interaction withnhp6High-mobility group non-histone chromatin protein (predicted) Positive GeneticPMID:18818364
positive genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withnot3CCR4-Not complex subunit Not3/5 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withnrm1MBF complex corepressor Nrm1 Negative GeneticPMID:22681890
positive genetic interaction withnup131nucleoporin Nup131 Positive GeneticPMID:18818364
negative genetic interaction withnup40nucleoporin Nup40 Negative GeneticPMID:18818364
positive genetic interaction withpar1protein phosphatase regulatory subunit Par1 Positive GeneticPMID:18818364
positive genetic interaction withpar1protein phosphatase regulatory subunit Par1 Positive GeneticPMID:22681890
negative genetic interaction withpdp2PWWP domain protein Pdp2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpek1MAP kinase kinase Pek1 Negative GeneticPMID:18818364
positive genetic interaction withpfd1prefoldin subunit 1 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withphp3CCAAT-binding factor complex subunit Php3 Positive GeneticPMID:22681890
positive genetic interaction withphp5CCAAT-binding factor complex subunit Php5 Positive GeneticPMID:22681890
negative genetic interaction withpht1histone H2A variant H2A.Z, Pht1 Negative GeneticPMID:22681890
negative genetic interaction withpku80Ku domain protein Pku80 Negative GeneticPMID:22681890
positive genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Positive GeneticPMID:18818364
negative genetic interaction withpng2ING family homolog Png2 Negative GeneticPMID:22681890
negative genetic interaction withpnk1DNA kinase/phosphatase Pnk1 Negative GeneticPMID:18818364
positive genetic interaction withpob3FACT complex subunit Pob3 Positive GeneticPMID:22681890
positive genetic interaction withppa2serine/threonine protein phosphatase Ppa2 Positive GeneticPMID:22681890
negative genetic interaction withpph3serine/threonine protein phosphatase, PP4 complex subunit Pph3 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withppk15serine/threonine protein kinase Ppk15 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withppk16serine/threonine protein kinase Ppk16 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withppk29Ark1/Prk1 family protein kinase Ppk29 Negative GeneticPMID:18818364
negative genetic interaction withppk29Ark1/Prk1 family protein kinase Ppk29 Negative GeneticPMID:22681890
positive genetic interaction withppk8serine/threonine protein kinase Ppk8 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withprp4serine/threonine protein kinase Prp4 Negative GeneticPMID:22681890
negative genetic interaction withprw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
negative genetic interaction withpsl1cyclin pho85 family Psl1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
positive genetic interaction withptc2protein phosphatase 2C Ptc2 Positive GeneticPMID:22681890
positive genetic interaction withpuf3RNA-binding protein Puf3 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withpyp1tyrosine phosphatase Pyp1 Positive GeneticPMID:22681890
positive genetic interaction withpyp2tyrosine phosphatase Pyp2 Positive GeneticPMID:22681890
negative genetic interaction withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Negative GeneticPMID:18818364
positive genetic interaction withrdh54ATP-dependent DNA helicase Rdh54 Positive GeneticPMID:18818364
negative genetic interaction withrdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:18818364
positive genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Positive GeneticPMID:18818364
positive genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Positive GeneticPMID:22681890
positive genetic interaction withrec14Ski complex subunit Rec14 Positive GeneticPMID:18818364
positive genetic interaction withres1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
positive genetic interaction withres2MBF transcription factor complex subunit Res2 Positive GeneticPMID:18818364
positive genetic interaction withrnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Positive GeneticPMID:18818364
negative genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withrox3mediator complex subunit Med19/Rox3 Positive GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:18818364
negative genetic interaction withrpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
negative genetic interaction withrpb7DNA-directed RNA polymerase complex II subunit Rpb7 Negative GeneticPMID:22681890
negative genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withrsv2transcription factor Rsv2 Negative GeneticPMID:18818364
negative genetic interaction withrsv2transcription factor Rsv2 Negative GeneticPMID:22681890
positive genetic interaction withrtt109RTT109 family histone lysine acetyltransferase Positive GeneticPMID:18818364
negative genetic interaction withrxt2histone deacetylase complex subunit Rxt2 Negative GeneticPMID:22681890
enhances phenotype ofrxt2histone deacetylase complex subunit Rxt2 Phenotypic EnhancementPMID:19547744
positive genetic interaction withryh1GTPase Ryh1 Positive GeneticPMID:18818364
positive genetic interaction withsan1sir antagonist, ubiquitin-protein ligase E3 Positive GeneticPMID:18818364
positive genetic interaction withsck2serine/threonine protein kinase Sck2 Positive GeneticPMID:24463365
negative genetic interaction withsdu1PPPDE peptidase family (predicted) Negative GeneticPMID:18818364
negative genetic interaction withsen1ATP-dependent 5' to 3' DNA/RNA helicase Sen1 Negative GeneticPMID:22681890
positive genetic interaction withser2phosphoserine phosphatase Ser2 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
negative genetic interaction withset1histone lysine methyltransferase Set1 Negative GeneticPMID:22681890
positive genetic interaction withset3histone lysine methyltransferase Set3 Positive GeneticPMID:18818364
negative genetic interaction withset5histone lysine methyltransferase Set5 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withset9histone lysine H3-K20 methyltransferase Set9 Negative GeneticPMID:18818364
positive genetic interaction withsgf29SAGA complex subunit Sgf29 Positive GeneticPMID:18818364
negative genetic interaction withshg1Set1C complex subunit Shg1 Negative GeneticPMID:22681890
positive genetic interaction withshk2PAK-related kinase Shk2 Positive GeneticPMID:18818364
positive genetic interaction withsir2Sirtuin family histone deacetylase Sir2 Positive GeneticPMID:18818364
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:18818364
negative genetic interaction withSPAC12G12.01cSEA complex subunit, ubiquitin-protein ligase E3 Negative GeneticPMID:18818364
positive genetic interaction withSPAC139.01cnuclease, XP-G family (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPAC144.05ATP-dependent DNA helicase/ ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPAC644.09alanine racemase (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPBC16C6.05mitochondrial translation initiation factor (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPBC17A3.03cphosphoprotein phosphatase (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC30B4.02cR3H and G-patch domain, implicated in splicing (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:18818364
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
positive genetic interaction withSPBC354.09cTre1 family protein, involved in vacuolar protein degradation (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPBC354.09cTre1 family protein, involved in vacuolar protein degradation (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC3F6.01cserine/threonine protein phosphatase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC83.05mitochondrial RNA-binding protein (predicted) Negative GeneticPMID:18818364
negative genetic interaction withSPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC8D2.16cDUF171 family protein Negative GeneticPMID:18818364
positive genetic interaction withSPCC126.13chistone deacetylase complex subunit, SAP128 family (predicted) Positive GeneticPMID:18818364
positive genetic interaction withSPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:18818364
negative genetic interaction withSPCC645.13transcription elongation regulator (predicted) Negative GeneticPMID:18818364
negative genetic interaction withspf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
positive genetic interaction withspn1mitotic septin Spn1 Positive GeneticPMID:18818364
positive genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Positive GeneticPMID:18818364
negative genetic interaction withspp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:18818364
negative genetic interaction withspp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:22681890
positive genetic interaction withsrb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
negative genetic interaction withsrp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
negative genetic interaction withssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Negative GeneticPMID:22681890
positive genetic interaction withssr3SWI/SNF and RSC complex subunit Ssr3 Positive GeneticPMID:18818364
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:18818364
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:18818364
negative genetic interaction withswd1Set1C complex subunit Swd1 Negative GeneticPMID:22681890
negative genetic interaction withswd22mRNA cleavage and polyadenylation specificity factor complex subunit, WD repeat protein Swd22 Negative GeneticPMID:18818364
positive genetic interaction withswr1SNF2 family ATP-dependent DNA helicase Swr1 Positive GeneticPMID:18818364
negative genetic interaction withtas3RITS complex subunit 3 Negative GeneticPMID:18818364
negative genetic interaction withtas3RITS complex subunit 3 Negative GeneticPMID:22681890
positive genetic interaction withtea2kinesin-like protein Tea2 Positive GeneticPMID:18818364
negative genetic interaction withtma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
positive genetic interaction withtoe4transcription factor, zf-fungal binuclear cluster type(predicted) Positive GeneticPMID:18818364
positive genetic interaction withtom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withtop1DNA topoisomerase I Positive GeneticPMID:18818364
positive genetic interaction withtos4FHA domain protein Tos4 (predicted) Positive GeneticPMID:18818364
negative genetic interaction withtrs8502TRAPP complex subunit Trs85b (predicted) Negative GeneticPMID:18818364
negative genetic interaction withtsc1hamartin Negative GeneticPMID:22681890
positive genetic interaction withubc13ubiquitin conjugating enzyme E2 Ubc13 Positive GeneticPMID:18818364
positive genetic interaction withubc6ubiquitin conjugating enzyme E2 Ubc6 (predicted) Positive GeneticPMID:18818364
positive genetic interaction withubp3ubiquitin C-terminal hydrolase Ubp3 Positive GeneticPMID:18818364
negative genetic interaction withubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:18818364
negative genetic interaction withubp7ubiquitin C-terminal hydrolase Ubp7 Negative GeneticPMID:18818364
positive genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive GeneticPMID:18818364
positive genetic interaction withubp8SAGA complex ubiquitin C-terminal hydrolase Ubp8 Positive GeneticPMID:22681890
negative genetic interaction withubr1N-end-recognizing protein, UBR ubiquitin-protein ligase E3 Ubr1 Negative GeneticPMID:22681890
negative genetic interaction withuds1septation protein Uds1 Negative GeneticPMID:18818364
negative genetic interaction withufd2ubiquitin-protein ligase E4 Ufd2 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withung1uracil DNA N-glycosylase Ung1 Negative GeneticPMID:22681890
negative genetic interaction withusp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
negative genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:18818364
negative genetic interaction withutp16U3 snoRNP-associated protein Utp16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvps5retromer complex subunit Vps5 Negative GeneticPMID:22681890
positive genetic interaction withvps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
positive genetic interaction withxap5xap-5-like protein Positive GeneticPMID:24957674
positive genetic interaction withymr1phosphatidylinositol-3-phosphatase, myotubularin family (predicted) Positive GeneticPMID:18818364
negative genetic interaction withynd1nucleoside diphosphatase Ynd1 Negative GeneticPMID:22681890
negative genetic interaction withypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:18818364
positive genetic interaction withypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Positive GeneticPMID:18818364
External References
Database Identifier Description
NBRP SPAC19G12.08 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC19G12.08 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC19G12.08 BioGRID Interaction Datasets
Expression Viewer SPAC19G12.08 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC19G12.08 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC19G12.08 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC19G12.08 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC19G12.08 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC19G12.08 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC19G12.08 Cell Cycle Data
GEO SPAC19G12.08 GEO profiles
PInt SPAC19G12.08 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC19G12.08 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC19G12.08 Fission yeast phenotypic data & analysis
SPD / RIKEN20/20F03Orfeome Localization Data
UniProtKB/SwissProtO13846Ceramide very long chain fatty acid hydroxylase-like protein C19G12.08
ModBaseO13846Database of comparative protein structure models
STRINGO13846Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594423sphingosine hydroxylase Scs7
RefSeq mRNANM_001019852972h- sphingosine hydroxylase Scs7 (scs7), mRNA
European Nucleotide ArchiveCAB10119.1ENA Protein Mapping
UniParcUPI000006B93AUniProt Archive

Literature for scs7

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Release Version: PomBase:25_50 - 10 Mar 2015