SPAC1B3.09c


Gene Standard NameUnassigned Characterisation Statusbiological role inferred
Systematic IDSPAC1B3.09c Feature Typeprotein coding
Synonyms Name Description
ProductNoc2p-Noc3p complex subunit Noc2 family (predicted) Product Size528aa, 60.79 kDa
Genomic Location Chromosome I, 4945814-4944132 (1683nt); CDS:4945814-4944228 (1587nt)

Ensembl Gene Location
GO Biological Process
Term NameCount
ribosomal subunit export from nucleus28
Annotation ExtensionEvidenceWith/FromReference
ribosome biogenesis337
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Noc1p-Noc2p complex3
Annotation ExtensionEvidenceWith/FromReference
Noc2p-Noc3p complex3
Annotation ExtensionEvidenceWith/FromReference
nucleolus366
Annotation ExtensionEvidenceWith/FromReference
nucleus2690
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Inviable

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationSPAC1B3.09cΔ1450

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, without cell division, with normal germ tube morphologySPAC1B3.09cΔ303
inviable sporeSPAC1B3.09cΔ475
inviable vegetative cell with abnormal cell morphologySPAC1B3.09cΔ371
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4945814..4944132
3' UTR4944227..4944132PMID:18641648
3' UTR4944227..4944132PMID:20118936
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03715 Pfam IPR005343 Nucleolar complex protein 2 231 525 2
PTHR12687 HMMPANTHER IPR005343 Nucleolar complex protein 2 217 524 2
SSF48371 SuperFamily IPR016024 Armadillo-type fold 169 461 130

View domain organization at Pfam

Protein Properties

Ave. residue weight 115.13 Da
Charge 15.50
Codon Adaptation Index 0.41
Isoelectric point 9.22
Molecular weight 60.79 kDa
Number of residues 528
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1675
present during mitotic M phaseS79
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S79 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPAC1B3.09c

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
5376during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3767during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4969during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4365during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
5521during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
1723.69during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4.1during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.86during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3422
conserved in vertebrates3397
conserved in eukaryotes only2504
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Load gene that interact genetically with SPAC1B3.09c into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withmid1medial ring protein Mid1 Positive GeneticPMID:22681890
positive genetic interaction withset1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
positive genetic interaction withrik1silencing protein Rik1 Positive GeneticPMID:22681890
positive genetic interaction withatg6autophagy associated beclin family protein Atg6 Positive GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
positive genetic interaction withlsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:22681890
positive genetic interaction withubp2ubiquitin C-terminal hydrolase Ubp2 Positive GeneticPMID:22681890
positive genetic interaction withamk2AMP-activated protein kinase beta subunit Amk2 Positive GeneticPMID:22681890
positive genetic interaction withSPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
positive genetic interaction withknd1Cullin-associated NEDD8-dissociated protein Knd1 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withssp2AMP-activated protein serine/threonine kinase alpha subunit Ssp2 Positive GeneticPMID:22681890
positive genetic interaction withSPCC1223.01ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:22681890
positive genetic interaction withmsa1RNA-binding protein Msa1 Positive GeneticPMID:22681890
negative genetic interaction withphp5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC2F3.16ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withphp3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
negative genetic interaction withSPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withmkh1MEK kinase (MEKK) Mkh1 Negative GeneticPMID:22681890
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
negative genetic interaction withbun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:22681890
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witharp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
negative genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
negative genetic interaction withatp11mitochondrial F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpmc2mediator complex subunit Med1 Negative GeneticPMID:22681890
negative genetic interaction withgcn2eIF2 alpha kinase Gcn2 Negative GeneticPMID:22681890
negative genetic interaction withace2transcription factor Ace2 Negative GeneticPMID:22681890
negative genetic interaction withtsc2tuberin Negative GeneticPMID:22681890
negative genetic interaction withdad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
negative genetic interaction withvps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
negative genetic interaction withccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgcn20AAA family ATPase Gcn20 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnup40nucleoporin Nup40 Negative GeneticPMID:22681890
negative genetic interaction withsts5RNB-like protein Negative GeneticPMID:22681890
negative genetic interaction withxap5xap-5-like protein Negative GeneticPMID:24957674
negative genetic interaction withlub1WD repeat protein Lub1 Negative GeneticPMID:22681890
negative genetic interaction withpuf1pumilio family RNA-binding protein Puf1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
negative genetic interaction withtsc1hamartin Negative GeneticPMID:22681890
negative genetic interaction withkin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
negative genetic interaction withcph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
negative genetic interaction withpst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
negative genetic interaction withrpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
negative genetic interaction withcdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
negative genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
negative genetic interaction withalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
negative genetic interaction withcsn2COP9/signalosome complex subunit Csn2 Negative GeneticPMID:22681890
negative genetic interaction withdad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
negative genetic interaction withdak1dihydroxyacetone kinase Dak1 Negative GeneticPMID:22681890
negative genetic interaction withpob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
negative genetic interaction withpof13F-box protein Pof13 Negative GeneticPMID:22681890
negative genetic interaction withdad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
negative genetic interaction withhip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
negative genetic interaction withdbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
negative genetic interaction withhip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
negative genetic interaction withddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC1B3.09c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1B3.09c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1B3.09c BioGRID Interaction Datasets
Expression Viewer SPAC1B3.09c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1B3.09c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1B3.09c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1B3.09c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1B3.09c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1B3.09c Transcriptome Viewer (Bähler Lab)
GEO SPAC1B3.09c GEO profiles
PInt SPAC1B3.09c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1B3.09c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1B3.09c Fission yeast phenotypic data & analysis
Cyclebase SPAC1B3.09c.1 Cell Cycle Data
SPD / RIKEN25/25E09Orfeome Localization Data
UniProtKB/SwissProtO13874Uncharacterized NOC2 family protein C1B3.09c
ModBaseO13874Database of comparative protein structure models
STRINGO13874Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594793Noc2p-Noc3p complex subunit Noc2 family (predicted)
RefSeq mRNANM_001020221972h- Noc2p-Noc3p complex subunit Noc2 family (predicted) (SPAC1B3.09c), mRNA
European Nucleotide ArchiveAB027836ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveBAA87140ENA Protein Mapping
European Nucleotide ArchiveCAB11238ENA Protein Mapping
UniParcUPI000013AA9EUniProt Archive

Literature for SPAC1B3.09c

Search: Europe PMC or PubMed

Release Version: PomBase:30_57 - 27 Jan 2016