ypt4 (SPAC1B3.11c)

Gene Standard Nameypt4 ChromosomeI
Systematic IDSPAC1B3.11c Gene Start4950238
Synonyms Gene End4948541
ProductGTPase Ypt4 Gene Length1698
Feature Typeprotein coding CDS Start4950022
Name Description CDS End4949270
Characterisation Statuspublished CDS Length753

Ensembl Gene Location
Fission Yeast Phenotype Ontology
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyypt4delta (deletion)deletionPMID:20473289
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReference
GO:0003924GTPase activityISMPFAM:PF00071GO_REF:0000001
GO:0005525GTP bindingISMPFAM:PF00071GO_REF:0000001
GO Biological Process
Term IDTerm NameEvidenceWith/FromReference
GO:0006886intracellular protein transportICGO:0016192GO_REF:0000001
GO:0007264small GTPase mediated signal transductionIEAIPR001806, IPR003579GO_REF:0000002
GO:0033554cellular response to stressIEPPMID:12529438
GO:0060627regulation of vesicle-mediated transportISMPFAM:PF00071GO_REF:0000001
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0005886plasma membraneIEASL-0039GO_REF:0000039
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
149502384949923
249498744948541

References

Region Start End Reference
three_prime_UTR49492694948541PMID:21511999
three_prime_UTR49492694948541PMID:21511999
five_prime_UTR49502384950023PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00071 IPR001806 Pfam Small GTPase superfamily 11 176 18
SM00175 IPR003579 SMART Small GTPase superfamily, Rab type 10 178 10
PS51419 Prosite Profiles 5 234 9
G3DSA:3.40.50.300 Gene3D 3 197 279
SSF52540 SuperFamily 5 186 294
PR00449 IPR001806 PRINTS Small GTPase superfamily 153 175 19
PR00449 IPR001806 PRINTS Small GTPase superfamily 55 77 19
PR00449 IPR001806 PRINTS Small GTPase superfamily 10 31 19
PR00449 IPR001806 PRINTS Small GTPase superfamily 117 130 19
PR00449 IPR001806 PRINTS Small GTPase superfamily 33 49 19
PTHR24073 hmmpanther 1 197 9
TIGR00231 IPR005225 tigrfam Small GTP-binding protein domain 8 168 35

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0001421Ypt subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001421

Protein Properties

Ave. residue weight 112.26 Da
Charge -3.00
Isoelectric point 5.35
Molecular weight 26.27 kDa
Number of residues 234
Sequence
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000005,
PECO:0000014
population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population_wide0.18PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005
population_wide0.34PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Positive GeneticPMID:22681890
sts5RNB-like protein Negative GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC1B3.11c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1B3.11c Retrieval of eukaryotic orthologs
BioGrid SPAC1B3.11c BioGRID Interaction Datasets
Bähler Lab SPAC1B3.11c Cell Cycle Expression Profile
Bähler Lab SPAC1B3.11c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1B3.11c Pheromone response/mating expression profiles
Bähler Lab SPAC1B3.11c Environmental stress expression profiles
Bähler Lab SPAC1B3.11c Bähler Lab Transcriptome Viewer
Cyclebase SPAC1B3.11c Cell Cycle Data
PInt SPAC1B3.11c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC1B3.11c Entrez Gene
WikiGene2542113GTPase Ypt4
Uniprot_genenameYPT4
EntrezGene2542113GTPase Ypt4
UniProtKB/SwissProtO13876GTP-binding protein ypt4
ModBaseO13876Database of comparative protein structure models
Pfam Protein DomainsO13876Pfam Domain Arrangement
RefSeq PeptideNP_594796GTPase Ypt4
RefSeq mRNANM_001020224972h- GTPase Ypt4 (ypt4), mRNA
European Nucleotide ArchiveCAB11239ENA Protein Mapping
SPD / RIKEN43/43B04Orfeome Localization Data
UniParcUPI000013BE3EUniProt Archive

Literature for ypt4

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013