vht1 (SPAC1B3.16c)

Gene Standard Namevht1 ChromosomeI
Systematic IDSPAC1B3.16c Gene Start4961033
Synonyms Gene End4958698
Productvitamin H transporter Vth1 Gene Length2336
Feature Typeprotein coding CDS Start4960800
Name Description CDS End4959094
Characterisation Statuspublished CDS Length1707

Ensembl Gene Location
  1. SPAC1B3.13
  2. vma3
  3. SPAC1B3.15c
  4. vht1
  5. SPNCRNA.1039
  6. SPNCRNA.256
  7. clr2
  8. mrps18
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyvht1delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0015225biotin transporter activityIGISGD:S000003297PMID:12557275
GO:0015293symporter activityIEAUniProtKB:KW-0769GO_REF:0000037
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0015878biotin transport
heterologous_systemIGISGD:S000003297PMID:12557275
GO:0055085transmembrane transportIEAIPR011701GO_REF:0000002
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005794Golgi apparatusIDAPMID:16823372
GO:0005887integral to plasma membraneTASPMID:12557275
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
149610334958698

References

Region Start End Reference
three_prime_UTR49590934958698PMID:21511999
three_prime_UTR49590934958698PMID:21511999
five_prime_UTR49610334960801PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF07690 IPR011701 Pfam Major facilitator superfamily 89 487 48
TMhelix TMHMM 473 495 955
TMhelix TMHMM 187 209 955
TMhelix TMHMM 86 108 955
TMhelix TMHMM 382 404 955
TMhelix TMHMM 411 428 955
TMhelix TMHMM 259 281 955
TMhelix TMHMM 158 177 955
TMhelix TMHMM 438 460 955
TMhelix TMHMM 510 528 955
TMhelix TMHMM 123 145 955
TMhelix TMHMM 222 244 955
TMhelix TMHMM 345 367 955
G3DSA:1.20.1250.20 Gene3D 344 532 67
G3DSA:1.20.1250.20 Gene3D 80 285 67
SSF103473 IPR016196 SuperFamily 323 524 74
SSF103473 IPR016196 SuperFamily 77 284 74
PTHR11662 hmmpanther 41 558 12
PTHR11662:SF2 hmmpanther 41 558 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.60 Da
Charge 8.00
Isoelectric point 8.04
Molecular weight 62.82 kDa
Number of residues 568
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide4145.35PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.78PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide15PMID:23101633
Complementation
DescriptionQualifierReference
functionally complements S. cerevisiae VHT1 PMID:12557275
functionally complements S. cerevisiae vht1full PMID:12557275
Genome Organisation
DescriptionQualifierReference
tandem duplication
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in bacteria
conserved in archaea
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
tsc2tuberin Negative GeneticPMID:22681890
vph2endoplasmic reticulum membrane protein involved in assembly of the V-ATPase (predicted) Negative GeneticPMID:22681890
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
dak1dihydroxyacetone kinase Dak1 Negative GeneticPMID:22681890
rok1ATP-dependent RNA helicase Rok1 (predicted) Negative GeneticPMID:22681890
rpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:22681890
mid1medial ring protein Mid1 Positive GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
nup40nucleoporin Nup40 Negative GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
fft3fun thirty related protein Fft3 Positive GeneticPMID:22681890
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Negative GeneticPMID:22681890
tsc1hamartin Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
dbr1RNA lariat debranching enzyme Dbr1 Negative GeneticPMID:22681890
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
sts5RNB-like protein Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
SPAC1565.07cTATA-binding protein (predicted) Positive GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
atg6beclin family protein, involved in autophagy Positive GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
SPAC2F3.16ubiquitin-protein ligase E3 (predicted) Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Negative GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor Reb1 Negative GeneticPMID:22681890
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
amk2AMP-activated protein kinase beta subunit Amk2 Positive GeneticPMID:22681890
bun107WD repeat protein, human WDR48 family Bun107 Negative GeneticPMID:22681890
SPCC1223.01ubiquitin-protein ligase E3 (predicted) Positive GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Negative GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Positive GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
SPBC29A3.09cAAA family ATPase Gcn20 (predicted) Negative GeneticPMID:22681890
php3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
ace2transcription factor Ace2 Negative GeneticPMID:22681890
msa1RNA-binding protein Msa1 Positive GeneticPMID:22681890
pof13F-box protein Pof13 Negative GeneticPMID:22681890
lsk1P-TEFb-associated cyclin-dependent protein kinase Lsk1 Positive GeneticPMID:22681890
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
ddb1damaged DNA binding protein Ddb1 Negative GeneticPMID:22681890
rik1silencing protein Rik1 Positive GeneticPMID:22681890
csn2COP9/signalosome complex subunit Csn2 Negative GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
php5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
SPBC31F10.10czf-MYND type zinc finger protein Negative GeneticPMID:22681890
SPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
ubp2ubiquitin C-terminal hydrolase Ubp2 Positive GeneticPMID:22681890
mkh1MEK kinase (MEKK) Mkh1 Negative GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Negative GeneticPMID:22681890
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
gcn2eIF2 alpha kinase Gcn2 Negative GeneticPMID:22681890
vps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
ssp2serine/threonine protein kinase Ssp2 Positive GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC1B3.16c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1B3.16c Retrieval of eukaryotic orthologs
BioGrid SPAC1B3.16c BioGRID Interaction Datasets
Bähler Lab SPAC1B3.16c Cell Cycle Expression Profile
Bähler Lab SPAC1B3.16c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1B3.16c Pheromone response/mating expression profiles
Bähler Lab SPAC1B3.16c Environmental stress expression profiles
Bähler Lab SPAC1B3.16c Bähler Lab Transcriptome Viewer
Cyclebase SPAC1B3.16c Cell Cycle Data
PInt SPAC1B3.16c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC1B3.16c Entrez Gene
WikiGene2542518vitamin H transporter Vth1
Uniprot_genenameVHT1
EntrezGene2542518vitamin H transporter Vth1
UniProtKB/SwissProtO13880Vitamin H transporter 1
ModBaseO13880Database of comparative protein structure models
Pfam Protein DomainsO13880Pfam Domain Arrangement
RefSeq PeptideNP_594801vitamin H transporter Vth1
RefSeq mRNANM_001020229972h- vitamin H transporter Vth1 (vht1), mRNA
European Nucleotide ArchiveAAO22560ENA Protein Mapping
European Nucleotide ArchiveCAB11242ENA Protein Mapping
SPD / RIKEN35/35E01Orfeome Localization Data
UniParcUPI0000005B67UniProt Archive

Literature for vht1
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013