SPAC1F7.10


Gene Standard NameUnassigned Characterisation Statusconserved unknown
Systematic IDSPAC1F7.10 Feature Typeprotein coding
Synonyms Name Description
Producthydantoin racemase family (predicted) Product Size238aa, 25.43 kDa
Genomic Location Chromosome I, 4243421-4244823 (1403nt); CDS:4243969-4244685 (717nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
racemase activity, acting on amino acids and derivatives7
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2306
Annotation ExtensionEvidenceWith/FromReference
nucleus2692
Annotation ExtensionEvidenceWith/FromReference
FYPO Single-Allele Phenotypes
Gene Deletion Viability: Viable

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationSPAC1F7.10Δ3837

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologySPAC1F7.10Δ3100
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons4243421..4244823
5' UTR4243421..4243968PMID:21511999
3' UTR4244686..4244823PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01177 Pfam IPR015942 Asp/Glu/hydantoin racemase 4 214 2
PTHR28047:SF2 HMMPANTHER 1 238 1
PTHR28047 HMMPANTHER 1 238 1
3.40.50.1860 Gene3D IPR001920 Asp/Glu racemase 141 207 2
SSF53681 SuperFamily IPR001920 Asp/Glu racemase 161 222 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 106.85 Da
Charge -2.50
Codon Adaptation Index 0.43
Isoelectric point 5.62
Molecular weight 25.43 kDa
Number of residues 238
Sequence
Gene Expression

Quantitative Gene Expression

View graphical display of gene expression data for SPAC1F7.10

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
4095during GO:0000080PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3727during GO:0000084PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4876during GO:0000085PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3019during GO:0000087PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
3740.41during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
3410during GO:0072690PECO:0000005,
PECO:0000126
single cellmass spectrometry evidencePMID:24763107
4023.96during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.9during GO:0072690PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
0.9during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4605
conserved in bacteria1001
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Load genes that interact physically with SPAC1F7.10 into the Query Builder
View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
binds activation domain construct withspa2cell polarity protein Spa2 Two-hybridPMID:26771498
binds activation domain construct withSPCC576.02hydantoin racemase family (predicted) Two-hybridPMID:26771498
binds activation domain construct withSPAC1F7.10hydantoin racemase family (predicted) Two-hybridPMID:26771498
binds activation domain construct withimp1importin alpha Two-hybridPMID:26771498
binds activation domain construct withtfs1transcription elongation factor TFIIS Two-hybridPMID:26771498
binds activation domain construct withrcd1RNA-binding protein, CCR4-NOT complex subunit Rcd1 Two-hybridPMID:26771498
interacts withSPAC1F7.10hydantoin racemase family (predicted) PCAPMID:26771498
Genetic Interactions

Source: BioGRID

Load genes that interact genetically with SPAC1F7.10 into the Query Builder
View these interactions in esyN

Gene Product Evidence Reference
positive genetic interaction withxap5xap-5-like protein Positive GeneticPMID:24957674
positive genetic interaction withres1MBF transcription factor complex subunit Res1 Positive GeneticPMID:22681890
positive genetic interaction withusp102U1 snRNP-associated protein Usp102 Positive GeneticPMID:22681890
positive genetic interaction withfft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Positive GeneticPMID:22681890
negative genetic interaction withgcn2eIF2 alpha kinase Gcn2 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC1F7.10 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F7.10 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F7.10 BioGRID Interaction Datasets
Expression Viewer SPAC1F7.10 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F7.10 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F7.10 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F7.10 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F7.10 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F7.10 Transcriptome Viewer (Bähler Lab)
GEO SPAC1F7.10 GEO profiles
PInt SPAC1F7.10 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1F7.10 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1F7.10 Fission yeast phenotypic data & analysis
Cyclebase SPAC1F7.10.1 Cell Cycle Data
SPD / RIKEN08/08E04Orfeome Localization Data
UniProtKB/SwissProtQ09921Uncharacterized protein C1F7.10
ModBaseQ09921Database of comparative protein structure models
STRINGQ09921Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594496hydantoin racemase family (predicted)
RefSeq mRNANM_001019925972h- hydantoin racemase family (predicted) (SPAC1F7.10), mRNA
MetaCycPWY-6386UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)
MetaCycPWY-6387UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)
KEGG00471+5.1.1.3D-Glutamine and D-glutamate metabolism
UniPathwayUPA00219Cell wall biogenesis; peptidoglycan biosynthesis

Literature for SPAC1F7.10

Search: Europe PMC or PubMed

Release Version: PomBase:30_58 - 11 Mar 2016