yak3 (SPAC1F7.12)

Gene Standard Nameyak3 ChromosomeI
Systematic IDSPAC1F7.12 Gene Start4248777
SynonymsSPAC21E11.01, yakC Gene End4250231
Productaldose reductase ARK13 family YakC Gene Length1455
Feature Typeprotein coding CDS Start4249066
Name Description CDS End4250088
Characterisation Statuspublished CDS Length1023

Ensembl Gene Location
  1. SPAC1F7.09c
  2. SPAC1F7.10
  3. SPAC1F7.11c
  4. yak3
  5. rpl801
  6. pcr1
  7. aca1
  8. cyp8
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyyak3delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0016614oxidoreductase activity, acting on CH-OH group of donorsIDAPMID:12359080
NOT GO:0050235pyridoxal 4-dehydrogenase activityIDAPMID:12359080
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0033554cellular response to stressIEPPMID:12529438
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
142487774250231

References

Region Start End Reference
three_prime_UTR42500894250231PMID:21511999
three_prime_UTR42500894250231PMID:21511999
five_prime_UTR42487774249065PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00248 IPR023210 Pfam Aldo/keto reductase 16 312 15
G3DSA:3.20.20.100 IPR023210 Gene3D 3 324 15
SSF51430 IPR023210 SuperFamily 4 317 15
PTHR11732 IPR001395 hmmpanther Aldo/keto reductase 1 340 14
PTHR11732:SF12 hmmpanther 1 340 4

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.91 Da
Charge 0.50
Isoelectric point 6.74
Molecular weight 37.71 kDa
Number of residues 340
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide27365.62PMID:23101633
experimental evidencePECO:0000014,
PECO:0000005		population_wide12989.08PMID:23101633
RNA levelexperimental evidencePECO:0000014,
PECO:0000005		population_wide4.8PMID:23101633
expression microarray evidencecellular response to oxidative stressincreasedPMID:12529438
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2.5PMID:23101633
Species Distribution
DescriptionQualifierReference
no apparent S. cerevisiae ortholog
conserved in fungi
conserved in eukaryotes
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External References
Database Identifier Description
NBRP SPAC1F7.12 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F7.12 Retrieval of eukaryotic orthologs
BioGrid SPAC1F7.12 BioGRID Interaction Datasets
Bähler Lab SPAC1F7.12 Cell Cycle Expression Profile
Bähler Lab SPAC1F7.12 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC1F7.12 Pheromone response/mating expression profiles
Bähler Lab SPAC1F7.12 Environmental stress expression profiles
Bähler Lab SPAC1F7.12 Bähler Lab Transcriptome Viewer
Cyclebase SPAC1F7.12 Cell Cycle Data
PInt SPAC1F7.12 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC1F7.12 Entrez Gene
WikiGene2541648aldose reductase YakC
Uniprot_genenameYAKC
EntrezGene2541648aldose reductase YakC
UniProtKB/SwissProtQ09923Aldo-keto reductase yakc [NADP(+)]
ModBaseQ09923Database of comparative protein structure models
Pfam Protein DomainsQ09923Pfam Domain Arrangement
RefSeq PeptideNP_594498aldose reductase YakC
RefSeq mRNANM_001019927972h- aldose reductase YakC (yak3), mRNA
European Nucleotide ArchiveCAA91959ENA Protein Mapping
SPD / RIKEN15/15C12Orfeome Localization Data
UniParcUPI000013A107UniProt Archive

Literature for yak3
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013