rpl801 (SPAC1F7.13c)


Gene Standard Namerpl801 Characterisation Statusbiological_role_inferred
Systematic IDSPAC1F7.13c Feature Typeprotein coding
Synonymsrpk5a, rpl18, rpl2-1, rpl8-1, SPAC21E11.02c Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome I, 4251468-4250595 (874nt); CDS:4251418-4250657 (762nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
rRNA binding55
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation468
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2316
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationrpl801ΔNull3783

Cell Phenotype

Term NameAlleleExpressionCount
abnormal microtubule cytoskeleton morphology during mitotic interphaserpl801ΔNull186
abnormal mitotic cell cycle phaserpl801ΔNull117
viable vegetative cell with normal cell morphologyrpl801ΔNull3092
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
142514684250595

UTRs

Region Coordinates Reference
five_prime_UTR4251468..4251419PMID:21511999
three_prime_UTR4250656..4250595PMID:21511999
exon4251418..4250657
mRNA4251468..4250595
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00181 Pfam IPR022666 Ribosomal Proteins L2, RNA binding domain 15 89 4
PF03947 Pfam IPR022669 Ribosomal protein L2, C-terminal 96 228 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2, conserved site 196 207 4
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
PTHR13691:SF16 HMMPANTHER 1 253 3
4.10.950.10 Gene3D IPR014726 Ribosomal protein L2, domain 3 169 243 4
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 1 85 48
2.30.30.30 Gene3D IPR014722 Ribosomal protein L2 domain 2 89 168 13
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 2 96 57
SSF50104 SuperFamily IPR008991 Translation protein SH3-like domain 98 244 16
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 253 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1670
present during mitotic M phaseS11
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S11 PMID:21712547
phosphorylated residue 1923
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
307727during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
301113during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
313744during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
315965during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
308773during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
374427.3during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
39428.93during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
110during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
7.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000
conserved in metazoa3432
conserved in vertebrates3407
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byair1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
affinity captured bycwf10U5 snRNP GTPase subunit Cwf10 Affinity Capture-MSPMID:24442611
affinity captured byhhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
affinity captured byhhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
affinity captured bylea1U2 snRNP-associated protein Lea1 (predicted) Affinity Capture-MSPMID:24442611
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
External References
Database Identifier Description
NBRP SPAC1F7.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F7.13c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F7.13c BioGRID Interaction Datasets
Expression Viewer SPAC1F7.13c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F7.13c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F7.13c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F7.13c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F7.13c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F7.13c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1F7.13c Cell Cycle Data
GEO SPAC1F7.13c GEO profiles
PInt SPAC1F7.13c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1F7.13c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1F7.13c Fission yeast phenotypic data & analysis
SPD / RIKEN40/40A11Orfeome Localization Data
UniProtKB/SwissProtP0809360S ribosomal protein L2
ModBaseP08093Database of comparative protein structure models
STRINGP08093Network display of known and predicted interactions and functional associations
RefSeq mRNAXM_001713050972h- 60S ribosomal protein L2 (rpl801), mRNA
RefSeq PeptideXP_00171310260S ribosomal protein L2
European Nucleotide ArchiveBAA87149.1ENA Protein Mapping
European Nucleotide ArchiveCAA28710.1ENA Protein Mapping
European Nucleotide ArchiveCAA34428.1ENA Protein Mapping
European Nucleotide ArchiveCAA35971.1ENA Protein Mapping
European Nucleotide ArchiveCAA91960.1ENA Protein Mapping
European Nucleotide ArchiveCAB10155.1ENA Protein Mapping
European Nucleotide ArchiveCAB46697.1ENA Protein Mapping
UniParcUPI0000133ED3UniProt Archive

Literature for rpl801

Search: Europe PMC or PubMed

Release Version: PomBase:25_49 - 02 Feb 2015