rpl801 (SPAC1F7.13c)

Gene Standard Namerpl801 Characterisation Statusbiological role inferred
Systematic IDSPAC1F7.13c Feature Typeprotein coding
Synonymsrpk5a, rpl18, rpl2-1, rpl8-1, SPAC21E11.02c Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome I, 4251468-4250595 (874nt); CDS:4251418-4250657 (762nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
rRNA binding57
Annotation ExtensionEvidenceWith/FromReference
structural constituent of ribosome257
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation468
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
cytosolic large ribosomal subunit83
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
viable vegetative cell populationrpl801Δ3815

Cell Phenotype

Term NameGenotypesCount
abnormal microtubule cytoskeleton morphology during mitotic interphaserpl801Δ186
abnormal mitotic cell cycle phaserpl801Δ144
viable vegetative cell with normal cell morphologyrpl801Δ3095
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR4251468..4251419PMID:21511999
3' UTR4250656..4250595PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03947 Pfam IPR022669 Ribosomal protein L2, C-terminal 97 221 4
PF00181 Pfam IPR022666 Ribosomal Proteins L2, RNA binding domain 15 89 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2, conserved site 196 207 4
PTHR13691:SF16 HMMPANTHER 1 253 3
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
4.10.950.10 Gene3D IPR014726 Ribosomal protein L2, domain 3 169 243 4 Gene3D IPR014722 Ribosomal protein L2 domain 2 89 168 13 Gene3D IPR012340 Nucleic acid-binding, OB-fold 1 85 48
SSF50104 SuperFamily IPR008991 Translation protein SH3-like domain 98 244 16
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 2 96 57
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 251 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Codon Adpatation Index 0.76
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS11
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S11 PMID:21712547
phosphorylated residue 1930
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
307727during GO:0000080PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
301113during GO:0000084PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
313744during GO:0000085PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
315965during GO:0000087PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
374427.3during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
308773during GO:0072690PECO:0000005,
single cellmass spectrometry evidencePMID:24763107
39428.93during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
110during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
7.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in bacteria1000
conserved in metazoa3421
conserved in vertebrates3396

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byair1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
affinity captured bycid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
affinity captured bycwf10U5 snRNP GTPase subunit Cwf10 Affinity Capture-MSPMID:24442611
affinity captured bylea1U2 snRNP-associated protein Lea1 (predicted) Affinity Capture-MSPMID:24442611
affinity captured bysog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
affinity captured bytea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
External References
Database Identifier Description
NBRP SPAC1F7.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F7.13c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F7.13c BioGRID Interaction Datasets
Expression Viewer SPAC1F7.13c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F7.13c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F7.13c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F7.13c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F7.13c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F7.13c Transcriptome Viewer (Bähler Lab)
GEO SPAC1F7.13c GEO profiles
PInt SPAC1F7.13c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1F7.13c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1F7.13c Fission yeast phenotypic data & analysis
Cyclebase SPAC1F7.13c.1 Cell Cycle Data
SPD / RIKEN40/40A11Orfeome Localization Data
UniProtKB/SwissProtP0CT7060S ribosomal protein L2-A
ModBaseP0CT70Database of comparative protein structure models
STRINGP0CT70Network display of known and predicted interactions and functional associations
RefSeq mRNAXM_001713050972h- 60S ribosomal protein L2 (rpl801), mRNA
RefSeq PeptideXP_00171310260S ribosomal protein L2
European Nucleotide ArchiveAB027845ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCU329671ENA EMBL mapping
European Nucleotide ArchiveX05036ENA EMBL mapping
European Nucleotide ArchiveX16392ENA EMBL mapping
European Nucleotide ArchiveX51659ENA EMBL mapping
European Nucleotide ArchiveBAA87149ENA Protein Mapping
European Nucleotide ArchiveBAA87149.1ENA Protein Mapping
European Nucleotide ArchiveCAA28710ENA Protein Mapping
European Nucleotide ArchiveCAA28710.1ENA Protein Mapping
European Nucleotide ArchiveCAA34428ENA Protein Mapping
European Nucleotide ArchiveCAA34428.1ENA Protein Mapping
European Nucleotide ArchiveCAA35971ENA Protein Mapping
European Nucleotide ArchiveCAA35971.1ENA Protein Mapping
European Nucleotide ArchiveCAA91960ENA Protein Mapping
European Nucleotide ArchiveCAA91960.1ENA Protein Mapping
European Nucleotide ArchiveCAB10155ENA Protein Mapping
European Nucleotide ArchiveCAB10155.1ENA Protein Mapping
European Nucleotide ArchiveCAB46697ENA Protein Mapping
European Nucleotide ArchiveCAB46697.1ENA Protein Mapping
UniParcUPI0000133ED3UniProt Archive

Literature for rpl801

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015