rpl801 (SPAC1F7.13c)


Gene Standard Namerpl801 Characterisation Statusbiological_role_inferred
Systematic IDSPAC1F7.13c Feature Typeprotein coding
Synonymsrpk5a, rpl18, rpl2-1, rpl8-1, SPAC21E11.02c Name Description
Product60S ribosomal protein L8 (predicted) Product Size253aa, 27.10 kDa
Genomic Location Chromosome I, 4251468-4250595 (874nt); CDS:4251418-4250657 (762nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0019843rRNA bindingIEAUniProtKB-KW:KW-0699GO_REF:000003746
GO:0003735structural constituent of ribosomeISOSGD:S000001280GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0006412translationISOSGD:S000001280GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005829cytosolIDAPMID:168233722317
GO:0022625cytosolic large ribosomal subunitISOSGD:S000001280GO_REF:000002482
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopyrpl801ΔNullPECO:0000005, PECO:0000137PMID:236978063755
Microscopyrpl801ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopyrpl801ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
142514684250595

UTRs

Region Start End Reference
three_prime_UTR42506564250595PMID:21511999
five_prime_UTR42514684251419PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF03947 Pfam IPR022669 Ribosomal protein L2 96 228 4
PF00181 Pfam IPR022666 Ribosomal protein L2 15 89 4
PS00467 Prosite Patterns IPR022671 Ribosomal protein L2 196 207 4
PTHR13691 HMMPANTHER IPR002171 Ribosomal protein L2 1 253 4
PTHR13691:SF4 HMMPANTHER 1 253 3
G3DSA:2.40.50.140 Gene3D IPR012340 1 85 47
G3DSA:4.10.950.10 Gene3D IPR014726 169 243 4
G3DSA:2.30.30.30 Gene3D IPR014722 89 168 12
SSF50104 SuperFamily IPR008991 98 244 16
SSF50249 SuperFamily IPR012340 2 96 57
Low complexity (SEG) seg 235 250
Low complexity (SEG) seg 161 174
PIRSF002158 PIRSF IPR002171 Ribosomal protein L2 1 253 3

View domain organization at Pfam

Protein Properties

Ave. residue weight 107.12 Da
Charge 29.50
Isoelectric point 11.45
Molecular weight 27.10 kDa
Number of residues 253
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:195477441192
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
374427.3during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
39428.93during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
7.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
110during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3394
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
cid14poly(A) polymerase Cid14 Affinity Capture-MSPMID:20403971
air1zinc knuckle TRAMP complex subunit Air1 Affinity Capture-MSPMID:20403971
bdf2BET family double bromodomain protein Bdf2 Affinity Capture-MSPMID:24013502
sog2leucine-rich repeat protein Lrp1 Affinity Capture-MSPMID:23462181
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
tea1cell end marker Tea1 Affinity Capture-MSPMID:21652630
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
External References
Database Identifier Description
NBRP SPAC1F7.13c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F7.13c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F7.13c BioGRID Interaction Datasets
Expression Viewer SPAC1F7.13c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F7.13c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F7.13c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F7.13c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F7.13c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F7.13c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1F7.13c Cell Cycle Data
GEO SPAC1F7.13c GEO profiles
PInt SPAC1F7.13c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene580295260S ribosomal protein L8
WikiGene254119160S ribosomal protein L8
WikiGene254036660S ribosomal protein L8
EntrezGene580295260S ribosomal protein L8
EntrezGene254119160S ribosomal protein L8
EntrezGene254036660S ribosomal protein L8
SPD / RIKEN40/40A11Orfeome Localization Data
UniProtKB/SwissProtP0809360S ribosomal protein L2
ModBaseP08093Database of comparative protein structure models
StringP08093Network display of known and predicted interactions and functional associations
RefSeq_mRNA_predictedXM_001713050972h- 60S ribosomal protein L8 (rpl801), mRNA
RefSeq_peptide_predictedXP_00171310260S ribosomal protein L8
European Nucleotide ArchiveBAA87149ENA Protein Mapping
European Nucleotide ArchiveCAA28710ENA Protein Mapping
European Nucleotide ArchiveCAA34428ENA Protein Mapping
European Nucleotide ArchiveCAA35971ENA Protein Mapping
European Nucleotide ArchiveCAA91960ENA Protein Mapping
European Nucleotide ArchiveCAB10155ENA Protein Mapping
European Nucleotide ArchiveCAB46697ENA Protein Mapping
UniParcUPI0000133ED3UniProt Archive

Literature for rpl801

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014