ght3 (SPAC1F8.01)

Gene Standard Nameght3 Characterisation Statuspublished
Systematic IDSPAC1F8.01 Feature Typeprotein coding
Synonyms Name Description
Producthexose transmembrane transporter Ght3 Product Size555aa, 62.09 kDa
Genomic Location Chromosome I, 82746-84786 (2041nt); CDS:82936-84603 (1668nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
gluconate transmembrane transporter activity1
Annotation ExtensionEvidenceWith/FromReference
NOT D-glucose transmembrane transporter activity
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
gluconate transmembrane transport2
Annotation ExtensionEvidenceWith/FromReference
hexose transmembrane transport8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
integral component of plasma membrane51
Annotation ExtensionEvidenceWith/FromReference
plasma membrane251
Annotation ExtensionEvidenceWith/FromReference
plasma membrane of cell tip18
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
decreased cell population growth on gluconate carbon sourceght3Δ1
normal cell population growth during glucose starvationght3Δ8
normal growth on glucose carbon sourceght3Δ240
viable vegetative cell populationght3Δ3819

Cell Phenotype

Term NameGenotypesCount
viable vegetative cell with normal cell morphologyght3Δ3097
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR82746..82935AF017180
3' UTR84604..84786PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 Major facilitator, sugar transporter-like 10 466 16
TMhelix TMHMM 145 167 959
TMhelix TMHMM 329 348 959
TMhelix TMHMM 403 425 959
TMhelix TMHMM 5 22 959
TMhelix TMHMM 429 451 959
TMhelix TMHMM 300 322 959
TMhelix TMHMM 110 132 959
TMhelix TMHMM 182 199 959
TMhelix TMHMM 58 80 959
TMhelix TMHMM 87 106 959
TMhelix TMHMM 268 290 959
TMhelix TMHMM 368 390 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PS00217 Prosite Patterns IPR005829 Sugar transporter, conserved site 119 144 6
PS00216 Prosite Patterns IPR005829 Sugar transporter, conserved site 318 335 15
PTHR23500:SF131 HMMPANTHER 5 522 8
PTHR23500 HMMPANTHER 5 522 10
1.20.1250.20 Gene3D Sugar phosphate transporter 49 204 72
1.20.1250.20 Gene3D Sugar phosphate transporter 263 462 72
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 245 464 76
SSF103473 SuperFamily IPR020846 Major facilitator superfamily domain 46 214 76
SignalP-noTM signalp 1 21 208
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 6 463 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.88 Da
Charge 8.50
Isoelectric point 8.43
Molecular weight 62.09 kDa
Number of residues 555

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1674
present during mitotic M phaseS550
present during mitotic M phaseS542
present during mitotic M phaseS539
present during mitotic M phaseS547
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S539 PMID:21712547
present during mitotic M phase experimental evidence S542 PMID:21712547
present during mitotic M phase experimental evidence S547 PMID:21712547
present during mitotic M phase experimental evidence S550 PMID:21712547
Gene Expression

Qualitative Gene Expression

protein levelincreased during GO:0042149Western blot evidencePMID:25411338
RNA levelincreased during GO:0042149quantitative PCRPMID:25411338

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.15during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
Taxonomic Conservation
conserved in fungi4604
conserved in eukaryotes4514

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC1F8.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F8.01 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F8.01 BioGRID Interaction Datasets
Expression Viewer SPAC1F8.01 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F8.01 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F8.01 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F8.01 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F8.01 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F8.01 Transcriptome Viewer (Bähler Lab)
GEO SPAC1F8.01 GEO profiles
PInt SPAC1F8.01 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1F8.01 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC1F8.01 Fission yeast phenotypic data & analysis
Cyclebase SPAC1F8.01.1 Cell Cycle Data
SPD / RIKEN45/45E06Orfeome Localization Data
UniProtKB/SwissProtQ92339High-affinity gluconate transporter ght3
ModBaseQ92339Database of comparative protein structure models
STRINGQ92339Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592790hexose transporter Ght3
RefSeq mRNANM_001018190972h- hexose transporter Ght3 (ght3), mRNA
European Nucleotide ArchiveAF051139ENA EMBL mapping
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveAAC63975ENA Protein Mapping
European Nucleotide ArchiveAAC63975.1ENA Protein Mapping
European Nucleotide ArchiveCAB03595ENA Protein Mapping
European Nucleotide ArchiveCAB03595.1ENA Protein Mapping
UniParcUPI000012B420UniProt Archive

Literature for ght3

Search: Europe PMC or PubMed

Release Version: PomBase:29_56 - 12 Nov 2015