ght3 (SPAC1F8.01)


Gene Standard Nameght3 Characterisation Statuspublished
Systematic IDSPAC1F8.01 Feature Typeprotein coding
Synonyms Name Description
Producthexose transporter Ght3 Product Size555aa, 62.09 kDa
Genomic Location Chromosome I, 82746-84786 (2041nt); CDS:82936-84603 (1668nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015128gluconate transmembrane transporter activityIMPPMID:107358571
NOT GO:0055056D-glucose transmembrane transporter activityIMPPMID:10735857
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0035429gluconate transmembrane transportIMPPMID:107358571
GO:0035428hexose transmembrane transportTASPMID:107358578
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005887integral component of plasma membraneTASPMID:1073585750
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001830decreased cell population growth on gluconate carbon sourceCell growth assayght3ΔNullPMID:107358571
FYPO:0002060viable vegetative cell populationMicroscopyght3ΔNullPECO:0000005, PECO:0000137PMID:236978063751
Microscopyght3ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyght3ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
18274684786
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00083 Pfam IPR005828 General substrate transporter 10 466 15
TMhelix TMHMM 329 348 959
TMhelix TMHMM 87 106 959
TMhelix TMHMM 268 290 959
TMhelix TMHMM 300 322 959
TMhelix TMHMM 110 132 959
TMhelix TMHMM 182 199 959
TMhelix TMHMM 403 425 959
TMhelix TMHMM 5 22 959
TMhelix TMHMM 145 167 959
TMhelix TMHMM 58 80 959
TMhelix TMHMM 429 451 959
TMhelix TMHMM 368 390 959
PS50850 Prosite Profiles IPR020846 Major facilitator superfamily domain 9 456 55
PS00217 Prosite Patterns IPR005829 Sugar transporter, conserved site 119 144 6
PS00216 Prosite Patterns IPR005829 Sugar transporter, conserved site 318 335 15
PTHR24063:SF98 HMMPANTHER 3 493 8
PTHR24063 HMMPANTHER 3 493 11
1.20.1250.20 Gene3D 263 462 72
1.20.1250.20 Gene3D 49 204 72
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 245 464 76
SSF103473 SuperFamily IPR016196 Major facilitator superfamily domain, general substrate transporter 46 214 76
SignalP-noTM signalp 1 21 212
PR00171 PRINTS IPR003663 Sugar/inositol transporter 17 27 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 369 390 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 392 404 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 114 133 10
PR00171 PRINTS IPR003663 Sugar/inositol transporter 276 286 10
TIGR00879 tigrfam IPR003663 Sugar/inositol transporter 6 463 10

View domain organization at Pfam

Protein Properties

Ave. residue weight 111.88 Da
Charge 8.50
Isoelectric point 8.43
Molecular weight 62.09 kDa
Number of residues 555
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineexperimental evidenceS542PMID:217125471670
present during mitotic M phase
present during mitotic M phaseexperimental evidenceS539PMID:21712547
present during mitotic M phaseexperimental evidenceS550PMID:21712547
present during mitotic M phaseexperimental evidenceS547PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
0.15during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.1during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4599
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC1F8.01 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F8.01 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F8.01 BioGRID Interaction Datasets
Expression Viewer SPAC1F8.01 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F8.01 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F8.01 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F8.01 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F8.01 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F8.01 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1F8.01 Cell Cycle Data
GEO SPAC1F8.01 GEO profiles
PInt SPAC1F8.01 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC1F8.01 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN45/45E06Orfeome Localization Data
UniProtKB/SwissProtQ92339High-affinity gluconate transporter ght3
ModBaseQ92339Database of comparative protein structure models
STRINGQ92339Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592790hexose transporter Ght3
RefSeq mRNANM_001018190972h- hexose transporter Ght3 (ght3), mRNA
European Nucleotide ArchiveAAC63975.1ENA Protein Mapping
European Nucleotide ArchiveCAB03595.1ENA Protein Mapping
UniParcUPI000012B420UniProt Archive

Literature for ght3

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014