str3 (SPAC1F8.03c)


Gene Standard Namestr3 Characterisation Statuspublished
Systematic IDSPAC1F8.03c Feature Typeprotein coding
Synonyms Name Description
Productsiderophore-iron transporter Str3 Product Size630aa, 70.56 kDa
Genomic Location Chromosome I, 90300-88201 (2100nt); CDS:90259-88367 (1893nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0015343siderophore transmembrane transporter activityTASPMID:128884923
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0034755iron ion transmembrane transportTASPMID:1288849212
GO:0044718siderophore transmembrane transportTASPMID:128884923
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005737cytoplasmIDAPMID:168233724198
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopystr3ΔNullPMID:204732893755
Microscopystr3ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopystr3ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Target Of
RelationshipGeneProductReference
regulated by fep1 iron-sensing transcription factor Fep1 PMID:12888492
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
19030088201

UTRs

Region Start End Reference
five_prime_UTR9030090260PMID:21511999
three_prime_UTR8836688201PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF07690 Pfam IPR011701 Major facilitator superfamily 92 354 50
PF05977 Pfam IPR010290 Transmembrane secretion effector 414 523 1
TMhelix TMHMM 211 233 959
TMhelix TMHMM 82 104 959
TMhelix TMHMM 370 392 959
TMhelix TMHMM 119 141 959
TMhelix TMHMM 466 488 959
TMhelix TMHMM 303 325 959
TMhelix TMHMM 176 198 959
TMhelix TMHMM 243 262 959
TMhelix TMHMM 335 357 959
TMhelix TMHMM 503 525 959
TMhelix TMHMM 574 596 959
TMhelix TMHMM 407 429 959
TMhelix TMHMM 153 172 959
PTHR24003:SF8 HMMPANTHER 10 627 1
PTHR24003 HMMPANTHER 10 627 17
G3DSA:1.20.1250.20 Gene3D 88 262 69
G3DSA:1.20.1250.20 Gene3D 366 526 69
G3DSA:1.20.1250.20 Gene3D 571 611 69
SSF103473 SuperFamily IPR016196 72 283 76
SSF103473 SuperFamily IPR016196 365 525 76
Low complexity (SEG) seg 510 519
Low complexity (SEG) seg 474 487
Low complexity (SEG) seg 177 189

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 112.00 Da
Charge 7.50
Isoelectric point 8.50
Molecular weight 70.56 kDa
Number of residues 630
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00696phosphorylated residuePMID:195477441192
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreasedNorthern assay evidencePMID:23115244
during GO:0010106

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.76during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
0.072during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4564
conserved in eukaryotes4482
conserved in bacteria1001
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
vps35retromer complex subunit Vps35 Negative GeneticPMID:22681890
SPBC725.05cnucleotide pyrophosphatase (predicted) Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
cdt2WD repeat protein Cdt2 Positive GeneticPMID:22681890
SPAC1A6.03cphospholipase (predicted) Negative GeneticPMID:22681890
prp1U4/U6 x U5 tri-snRNP complex subunit Prp1 Negative GeneticPMID:22681890
SPBC16H5.13WD repeat protein, human WDR7 ortholog Negative GeneticPMID:22681890
SPBC713.07cvacuolar polyphosphatase (predicted) Negative GeneticPMID:22681890
whi5cell cycle transcriptional repressor Whi5 (predicted) Negative GeneticPMID:22681890
dad1DASH complex subunit Dad1 Positive GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC1F8.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC1F8.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC1F8.03c BioGRID Interaction Datasets
Expression Viewer SPAC1F8.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC1F8.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC1F8.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC1F8.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC1F8.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC1F8.03c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC1F8.03c Cell Cycle Data
GEO SPAC1F8.03c GEO profiles
PInt SPAC1F8.03c Protein-Protein Interaction Predictor (Bähler Lab)
WikiGene2541891siderophore-iron transporter Str3
EntrezGene2541891siderophore-iron transporter Str3
SPD / RIKEN26/26E04Orfeome Localization Data
UniProtKB/SwissProtQ92341Siderophore iron transporter 3
ModBaseQ92341Database of comparative protein structure models
StringQ92341Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_592792siderophore-iron transporter Str3
RefSeq mRNANM_001018192972h- siderophore-iron transporter Str3 (str3), mRNA
European Nucleotide ArchiveCAB03597ENA Protein Mapping
UniParcUPI000013A9C7UniProt Archive

Literature for str3

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014