rad57 (SPAC20H4.07)

Gene Standard Namerad57 ChromosomeI
Systematic IDSPAC20H4.07 Gene Start2122490
Synonymsrhp57, SPAC145.01 Gene End2124506
ProductRecA family ATPase Rad57/Rhp57 Gene Length2017
Feature Typeprotein coding CDS Start2123290
Name Description CDS End2124449
Characterisation Statuspublished CDS Length1160

Ensembl Gene Location
  1. tfs1
  2. fml2
  3. SPAC20H4.05c
  4. SPAC20H4.06c
  5. rad57
  6. SPNCRNA.796
  7. SPAC20H4.08
  8. SPAC20H4.09
  9. SPNCRNA.797
  10. ufd2
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000062abnormal nuclear morphologyno_name (unrecorded)unrecordedPMID:11560889
FYPO:0000085sensitive to camptothecincompetitive growth assay evidencerad57delta (deletion)deletionPMID:20537132
Cell growth assayrad57delta (deletion)deletionPMID:19185548
FYPO:0000088sensitive to hydroxyureaCell growth assayrad57delta (deletion)deletionPMID:19185548
FYPO:0000089sensitive to methyl methanesulfonateCell growth assayrad57delta (deletion)deletionPMID:19185548
Cell growth assayrad57delta (deletion)deletionPMID:19185548
FYPO:0000181abolished crossoverrad57delta (deletion)deletionPMID:17304215
FYPO:0000185decreased gene conversionrad57delta (deletion)deletionPMID:17304215
FYPO:0000199increased long tract gene conversionrad57delta (deletion)deletionPMID:17304215
FYPO:0000266sensitive to DNA damaging agentscompetitive growth assay evidencerad57delta (deletion)deletionPMID:20537132
competitive growth assay evidencerad57delta (deletion)deletionPMID:20537132
FYPO:0000268sensitive to UVcompetitive growth assay evidencerad57delta (deletion)deletionPMID:20537132
FYPO:0001122elongated vegetative cellno_name (unrecorded)unrecordedPMID:11560889
FYPO:0001164normal cell population growth on glucose carbon sourceCell growth assayrad57delta (deletion)deletionPMID:19185548
FYPO:0001491viable vegetative cellMicroscopyrad57delta (deletion)deletionPMID:20473289
FYPO:0001492elongated viable vegetative cellMicroscopyrad57delta (deletion)deletionPMID:19185548
FYPO:0001706normal DNA damage checkpoint during cellular response to ionizing radiationWestern blot assayrad57delta (deletion)deletionPMID:19185548
assayed_using chk1
FYPO:0001707increased DNA damage checkpoint activationWestern blot assayrad57delta (deletion)deletionPMID:19185548
assayed_using chk1
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0003677DNA bindingIEAIPR020588GO_REF:0000002
GO:0005524ATP bindingIEAUniProtKB:KW-0067GO_REF:0000037
GO:0033170protein-DNA loading ATPase activityTASPMID:17353272
GO:0046982protein heterodimerization activityIPIrad55PMID:11560889
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0000724double-strand break repair via homologous recombinationIGIrad2PMID:10747044
GO:0000730DNA recombinase assemblyIMPPMID:17304215
GO:0007131reciprocal meiotic recombinationIMPPMID:14668362
GO:0042148strand invasionTASPMID:17353272
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0033062Rhp55-Rhp57 complexNASGO_REF:0000001
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121224902123356
221234522124506

References

Region Start End Reference
three_prime_UTR21244502124506PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF08423 IPR013632 Pfam DNA recombination and repair protein Rad51, C-terminal 71 276 3
PS50162 IPR020588 Prosite Profiles DNA recombination/repair protein RecA/RadB, ATP-binding domain 75 266 4
G3DSA:3.40.50.300 Gene3D 74 351 279
SSF52540 SuperFamily 74 339 294
PIRSF005856 IPR016467 PIRSF DNA recombination and repair protein, RecA-like 1 343 3
PTHR22942 hmmpanther 1 354 4
PTHR22942:SF16 hmmpanther 1 354 1

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000539AAA family ATPaseTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000539
PBO:0001319RecA familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001319
PBO:0001320helix-hairpin-helixTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001320

Protein Properties

Ave. residue weight 112.24 Da
Charge 0.00
Isoelectric point 6.51
Molecular weight 39.73 kDa
Number of residues 354
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide1.1PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.38PMID:23101633
Misc
DescriptionQualifierReference
Rhp57 facilitates Rhp51 assembly at damage sites independently of Swi5 PMID:17304215
swi5delta rhp57delta double mutant produced each recombination class (gene conversion, crossover and long tract gene conversion) at frequencies similar to that of the rhp51delta single mutant PMID:17304215
increased frequency of long tract gene conversion in the rhp57 delta single mutant was suppressed in the swi5delta rhp57delta double mutant, to a level similar to that observed in the rhp51 mutant PMID:17304215
swi5delta rhp57delta double mutant showed a repair profile very similar to that of the rhp51delta single mutant PMID:17304215
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in archaea
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
srs2ATP-dependent DNA helicase, UvrD subfamily Synthetic RescuePMID:14993467
Phenotypic Enhancement
Synthetic RescuePMID:16135799
rhn1RNA polymerase II transcription termination factor homolog Positive GeneticPMID:22681890
SPAC630.10conserved eukaryotic protein, DUF3321 family Positive GeneticPMID:22681890
rad13DNA repair nuclease Rad13 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
prz1calcineurin responsive transcription factor Prz1 Negative GeneticPMID:22681890
wpl1Wings apart-like homolog Wpl1 Negative GeneticPMID:18818364
clr4histone H3 lysine methyltransferase Clr4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
fsv1SNARE Fsv1 Negative GeneticPMID:22681890
pli1SUMO E3 ligase Pli1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:21504829
SPCC553.01cmeiotic chromosome segregation protein (predicted) Positive GeneticPMID:22681890
SPBC28F2.08cHRD ubiquitin ligase complex subunit (predicted) Negative GeneticPMID:22681890
atb2tubulin alpha 2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
git3G-protein coupled receptor Git3 Positive GeneticPMID:22681890
SPCC1183.11MS ion channel protein 1 (predicted) Positive GeneticPMID:22681890
mst2histone acetyltransferase Mst2 Synthetic Growth DefectPMID:22184112
sif3Sad1 interacting factor 3 (predicted) Negative GeneticPMID:22681890
mus81Holliday junction resolvase subunit Mus81 Phenotypic EnhancementPMID:20655467
rap1telomere binding protein Rap1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mus7DNA repair protein Mus7/Mms22 Phenotypic EnhancementPMID:17660542
mug154conserved fungal protein Negative GeneticPMID:18818364
psk1serine/threonine protein kinase Psk1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
clr3histone deacetylase (class II) Clr3 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mcl1DNA polymerase alpha accessory factor Mcl1 Negative GeneticPMID:18818364
usp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
mug2cell surface glycoprotein, adhesion molecule (predicted), DUF1773 family protein 1 Negative GeneticPMID:22681890
rad8ubiquitin-protein ligase E3 Rad8 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
fep1iron-sensing transcription factor Fep1 Negative GeneticPMID:22681890
aut12autophagy associated protein Aut12 (predicted) Positive GeneticPMID:18818364
rhp14XP-A family homolog Rhp14 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ubc13ubiquitin conjugating enzyme Ubc13 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ask1DASH complex subunit Ask1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ccq1telomere maintenance protein Ccq1 Negative GeneticPMID:22681890
spf1Set1C PHD Finger protein Spf1 Negative GeneticPMID:18818364
bdf1Swr1 complex bromodomain subunit Brf1 Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
apl1AP-2 adaptor complex subunit Apl1 (predicted) Negative GeneticPMID:22681890
caf1CCR4-Not complex CAF1 family ribonuclease subunit Caf1 Negative GeneticPMID:18818364
SPBC2A9.11cnuclear export factor (predicted) Negative GeneticPMID:22681890
amk2AMP-activated protein kinase beta subunit Amk2 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
def1RNAPII degradation factor Def1 (predicted) Negative GeneticPMID:22681890
nth1DNA endonuclease III Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
brc1BRCT domain protein Brc1 Phenotypic SuppressionPMID:15972456
SPBC19F8.02nuclear distribution protein NUDC homolog Negative GeneticPMID:22681890
pzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
rhp7Rad7 homolog Rhp7 Negative GeneticPMID:18818364
SPBC31F10.02acyl-CoA hydrolase (predicted) Negative GeneticPMID:22681890
gpd3glyceraldehyde 3-phosphate dehydrogenase Gpd3 Negative GeneticPMID:22681890
SPAC30.02celongator complex associated protein Kti2 (predicted) Negative GeneticPMID:22681890
swd2Set1C complex subunit Swd2.1 Negative GeneticPMID:18818364
spo6Spo4-Spo6 kinase complex regulatory subunit Spo6 Negative GeneticPMID:18818364
cda1chitin deacetylase Cda1 Negative GeneticPMID:22681890
SPAC6G10.06FAD-dependent amino acid oxidase involved in late endosome to Golgi transport (predicted) Negative GeneticPMID:22681890
stc1LIM-like protein linking chromatin modification to RNAi, Stc1 Positive GeneticPMID:22681890
rad26ATRIP, ATR checkpoint kinase regulatory subunit Rad26 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
stg1SM22/transgelin-like actin modulating protein Stg1 Negative GeneticPMID:22681890
psl1cyclin pho85 family (predicted) Negative GeneticPMID:22681890
bob1prefoldin subunit 5 (predicted) Positive GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
swd3WD repeat protein Swd3 Negative GeneticPMID:18818364
spp27RNA polymerase I upstream activation factor complex subunit Spp27 Negative GeneticPMID:22681890
rpa12DNA-directed RNA polymerase complex I subunit Rpa12 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
swi5Swi5 protein Synthetic LethalityPMID:18388861
Phenotypic EnhancementPMID:14663140
Phenotypic EnhancementPMID:20655467
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rrp2ATP-dependent DNA helicase (predicted) Negative GeneticPMID:19185548
epe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:18818364
elp3elongator complex, histone acetyltransferase subunit Elp3 (predicted) Negative GeneticPMID:22681890
pho24-nitrophenylphosphatase Negative GeneticPMID:22681890
arf6ADP-ribosylation factor, Arf family Arf6 Negative GeneticPMID:22681890
rps120140S ribosomal protein S12 (predicted) Negative GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC1393.09cRWD domain protein, implicated in translation Negative GeneticPMID:22681890
hrp3ATP-dependent DNA helicase Hrp3 Negative GeneticPMID:22681890
SPAC869.03curea transporter (predicted) Negative GeneticPMID:22681890
pku80Ku domain protein Pku80 Positive GeneticPMID:22681890
Positive GeneticPMID:18818364
rpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:22681890
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:22681890
hus1checkpoint clamp complex protein Hus1 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
ser2phosphoserine phosphatase Ser2 (predicted) Negative GeneticPMID:18818364
pha2phrenate dehydratase Negative GeneticPMID:22681890
SPBC11C11.01U2-associated protein (predicted) Negative GeneticPMID:22681890
leu23-isopropylmalate dehydratase Leu2 (predicted) Positive GeneticPMID:22681890
rdp1RNA-directed RNA polymerase Rdp1 Negative GeneticPMID:22681890
rev3DNA polymerase zeta catalytic subunit Rev3 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
top1DNA topoisomerase I Positive GeneticPMID:22681890
SPCC736.02sequence orphan Negative GeneticPMID:22681890
ndk1nucleoside diphosphate kinase Ndk1 Positive GeneticPMID:22681890
rad2414-3-3 protein Rad24 Negative GeneticPMID:22681890
SPBC4C3.09acetylglucosaminyltransferase (predicted) Negative GeneticPMID:22681890
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBP16F5.05cribosome biogenesis protein Nop8 (predicted) Positive GeneticPMID:22681890
SPBC9B6.03zf-FYVE type zinc finger protein Positive GeneticPMID:22681890
SPCC794.01cglucose-6-phosphate 1-dehydrogenase (predicted) Positive GeneticPMID:22681890
SPBC21B10.03cataxin-2 homolog (predicted) Negative GeneticPMID:22681890
rev7DNA polymerase zeta Rev7 (predicted) Negative GeneticPMID:18818364
gpd1glycerol-3-phosphate dehydrogenase Gpd1 Negative GeneticPMID:22681890
fma1methionine aminopeptidase Fma1 (predicted) Negative GeneticPMID:22681890
SPBC1921.04cdubious Positive GeneticPMID:22681890
SPAP27G11.07cserine/threonine protein kinase (predicted) Negative GeneticPMID:22681890
crb2DNA repair protein Rad9 homolog, Rhp9 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
mrt4mRNA turnover and ribosome assembly protein Mrt4 (predicted) Negative GeneticPMID:22681890
SPAC5H10.04NADPH dehydrogenase (predicted) Negative GeneticPMID:22681890
rad3ATR checkpoint kinase Rad3 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
csn71COP9/signalosome complex subunit 7a (predicted) Positive GeneticPMID:22681890
sdh3succinate dehydrogenase (ubiquinone) cytochrome b subunit (predicted) Positive GeneticPMID:22681890
rad60DNA repair protein Rad60 Synthetic RescuePMID:16354704
SPCC1020.05phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
ubp16ubiquitin C-terminal hydrolase Ubp16 Positive GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Positive GeneticPMID:18818364
pmt3SUMO Negative GeneticPMID:22681890
pcf2CAF assembly factor (CAF-1) complex subunit B, Pcf2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPCC550.07acetamidase (predicted) Negative GeneticPMID:22681890
pof9F-box protein Pof9 Synthetic Growth DefectPMID:18931302
fbh1DNA helicase I Positive GeneticPMID:18818364
Synthetic RescuePMID:16135799
SPBC1773.06calcohol dehydrogenase (predicted) Positive GeneticPMID:22681890
rqh1RecQ type DNA helicase Rqh1 Synthetic RescuePMID:14993467
Synthetic RescuePMID:16354704
Synthetic RescuePMID:23297345
Synthetic RescuePMID:16135799
swi6HP1 family chromodomain protein Swi6 Synthetic Growth DefectPMID:18931302
exo1exonuclease I Exo1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
alp14TOG ortholog Alp14 Negative GeneticPMID:18818364
SPCC18.13tRNA (guanine-N7-)-methyltransferase subunit Trm82 (predicted) Positive GeneticPMID:18818364
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
rad2FEN-1 endonuclease Rad2 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
Synthetic LethalityPMID:10747044
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
rad17RFC related checkpoint protein Rad17 Negative GeneticPMID:22681890
Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
rrp1ATP-dependent DNA helicase (predicted) Negative GeneticPMID:19185548
erf2palmitoyltransferase Erf2 (predicted) Positive GeneticPMID:22681890
mto1MT organizer Mto1 Negative GeneticPMID:22681890
SPAC6G9.14RNA-binding protein (predicted) Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
fin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Negative GeneticPMID:18818364
pdh1DUF1751 family protein Negative GeneticPMID:22681890
SPBC18H10.07WW domain-binding protein 4 (predicted) Positive GeneticPMID:22681890
rpl35b60S ribosomal protein L35a (predicted) Negative GeneticPMID:22681890
gtb1gamma-tubulin Gtb1 Synthetic Growth DefectPMID:22737087
SPCC594.04csteroid oxidoreductase superfamily protein (predicted) Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
nem1Nem1-Spo7 phosphatase complex catalytic subunit Nem1 (predicted) Negative GeneticPMID:22681890
SPBC2G5.01ER protein involved in ER-nucleus signaling (predicted) Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:18818364
nif1SEL1 repeat protein Nif1 Synthetic Growth DefectPMID:18931302
mrpl39mitochondrial ribosomal protein subunit L39 (predicted) Negative GeneticPMID:22681890
SPAC4D7.06csiroheme synthase (predicted) Negative GeneticPMID:22681890
lub1WD repeat protein Lub1 Negative GeneticPMID:22681890
SPAC25B8.05tRNA-pseudouridine synthase (predicted) Negative GeneticPMID:22681890
sir2Sir2 family histone deacetylase Sir2 Negative GeneticPMID:18818364
SPAC5H10.07sequence orphan Negative GeneticPMID:22681890
bdc1bromodomain containing protein 1, Bdc1 Negative GeneticPMID:18818364
bun62WD repeat protein, human WDR20 family, Bun62 Negative GeneticPMID:22681890
rtt109RTT109 family histone lysine acetyltransferase Negative GeneticPMID:22681890
rpl270160S ribosomal protein L27 Negative GeneticPMID:22681890
csk1cyclin-dependent kinase activating kinase Csk1 Synthetic Growth DefectPMID:18231579
upf1ATP-dependent RNA helicase Upf1 Synthetic Growth DefectPMID:18931302
SPBPB10D8.06cmembrane transporter (predicted) Negative GeneticPMID:22681890
gcd10tRNA (m1A) methyltransferase, translation initiation factor eIF-3 gamma subunit Gcd10 (predicted) Negative GeneticPMID:22681890
ubp6ubiquitin C-terminal hydrolase Ubp6 Negative GeneticPMID:18818364
nup97nucleoporin Nic96 homolog Negative GeneticPMID:22681890
zds1zds family protein phosphatase type A regulator Zds1 (predicted) Negative GeneticPMID:18818364
pub3HECT-type ubiquitin-protein ligase Pub3 (predicted) Synthetic Growth DefectPMID:18931302
atl1alkyltransferase-like protein Atl1 Negative GeneticPMID:22681890
SPCC737.06cglutamate-cysteine ligase regulatory subunit (predicted) Positive GeneticPMID:22681890
SPBC56F2.03actin-like protein Arp10 (predicted) Negative GeneticPMID:22681890
SPBC1683.03cmembrane transporter (predicted) Negative GeneticPMID:22681890
mad2spindle checkpoint protein Mad2 Synthetic Growth DefectPMID:22737087
par1protein phosphatase regulatory subunit Par1 Negative GeneticPMID:18818364
gpd2glycerol-3-phosphate dehydrogenase Gpd2 Negative GeneticPMID:22681890
rec11meiotic cohesin complex subunit Rec11 Negative GeneticPMID:22681890
SPBC839.03cneddylation protein Dcn1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rpl160360S ribosomal protein L13/L16 (predicted) Positive GeneticPMID:22681890
ire1serine/threonine protein kinase, sensor for unfolded proteins in the ER Ire1 Negative GeneticPMID:22681890
hrq1RecQ type DNA helicase Hrq1 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ssr3SWI/SNF and RSC complex subunit Ssr3 Negative GeneticPMID:18818364
fta6Sim4 and Mal2 associated (4 and 2 associated) protein 6 Positive GeneticPMID:22681890
zfs1CCCH tandem zinc finger protein, human Tristetraprolin homolog Zfs1, involved in mRNA catabolism Positive GeneticPMID:22681890
swi10DNA repair endonuclease Swi10 Synthetic Growth DefectPMID:18931302
mug51variant protein kinase 19 family protein Negative GeneticPMID:22681890
SPAC23H4.13csequence orphan Negative GeneticPMID:22681890
pdp1PWWP domain protein Pdp1 Negative GeneticPMID:18818364
apt1adenine phosphoribosyltransferase (APRT) (predicted) Negative GeneticPMID:22681890
fkbp39FKBP-type peptidyl-prolyl cis-trans isomerase (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
SPBC1778.09GTPase activating protein (predicted) Negative GeneticPMID:22681890
cph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
sec74guanyl-nucleotide exchange factor Sec74 (predicted) Positive GeneticPMID:22681890
pac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:18818364
amo1nuclear rim protein Amo1 Negative GeneticPMID:18818364
nto1histone acetyltransferase complex subunit Nto1 (predicted) Positive GeneticPMID:22681890
set9histone lysine methyltransferase Set9 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
rhp18Rad18 homolog Rhp18 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:22681890
chk1Chk1 protein kinase Synthetic Growth DefectPMID:18931302
ccr4CCR4-Not complex subunit Ccr4 (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
klp6kinesin-like protein Klp6 Negative GeneticPMID:18818364
SPBC25H2.15SSU-rRNA maturation protein Tsr4 homolog 1 (predicted) Negative GeneticPMID:22681890
SPBC1289.14adducin (predicted) Negative GeneticPMID:22681890
sum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
ebs1EST1 family nonsense-mediated mRNA decay (NMD) pathway protein Ebs1 (predicted) Negative GeneticPMID:22681890
gcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Synthetic Growth DefectPMID:22184112
rad1checkpoint clamp complex protein Rad1 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
mms1E3 ubiquitin ligase complex subunit Mms1 (predicted) Synthetic LethalityPMID:21183410
shk2PAK-related kinase Shk2 Negative GeneticPMID:18818364
rhp23Rad23 homolog Rhp23 Negative GeneticPMID:22681890
mit1SHREC complex subunit Mit1 Negative GeneticPMID:18818364
dis323'-5'-exoribonuclease activity Dis3L2 Negative GeneticPMID:22681890
mok11alpha-1,3-glucan synthase Mok11 Negative GeneticPMID:22681890
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:22681890
ubc14ubiquitin conjugating enzyme Ubc14 (predicted) Negative GeneticPMID:22681890
otu2ubiquitin specific cysteine protease, OTU family, Otu2 Negative GeneticPMID:22681890
SPAC9.07cGTPase Rbg1 (predicted) Negative GeneticPMID:22681890
dmc1RecA family ATPase Dmc1 Phenotypic EnhancementPMID:14668362
eme1Holliday junction resolvase subunit Eme1 Negative GeneticPMID:18818364
SPCC18.17c26S proteasome non-ATPase regulatory subunit (predicted) Negative GeneticPMID:22681890
SPAC750.01aldo/keto reductase family protein Negative GeneticPMID:22681890
SPAC8C9.12cmitochondrial iron ion transporter (predicted) Negative GeneticPMID:22681890
rps40140S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
rik1silencing protein Rik1 Synthetic Growth DefectPMID:18931302
Negative GeneticPMID:18818364
csn3COP9/signalosome complex subunit Csn3 (predicted) Negative GeneticPMID:22681890
zip2vacuolar membrane zinc transporter (predicted) Negative GeneticPMID:22681890
taz1human TRF ortholog Taz1 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Negative GeneticPMID:18818364
SPAP27G11.02TPR repeat protein, involved in mitochondrial protein turnover (predicted) Negative GeneticPMID:22681890
SPAC9.08csteroid reductase (predicted) Negative GeneticPMID:22681890
elp5elongator complex subunit Elp5 (predicted) Negative GeneticPMID:18818364
cay1cactin, spliceosome complex subunit (predicted) Negative GeneticPMID:18818364
pot1telomere end-binding protein Pot1 Synthetic RescuePMID:23297345
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
Negative GeneticPMID:18818364
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
rad51RecA family recombinase Rad51/Rhp51 Two-hybridPMID:11560889
rlp1RecA family ATPase Rlp1 Two-hybridPMID:15336631
rad55RecA family ATPase Rad55/Rhp55 Affinity Capture-WesternPMID:11560889
Two-hybrid
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External References
Database Identifier Description
NBRP SPAC20H4.07 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC20H4.07 Retrieval of eukaryotic orthologs
BioGrid SPAC20H4.07 BioGRID Interaction Datasets
Bähler Lab SPAC20H4.07 Cell Cycle Expression Profile
Bähler Lab SPAC20H4.07 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC20H4.07 Pheromone response/mating expression profiles
Bähler Lab SPAC20H4.07 Environmental stress expression profiles
Bähler Lab SPAC20H4.07 Bähler Lab Transcriptome Viewer
Cyclebase SPAC20H4.07 Cell Cycle Data
PInt SPAC20H4.07 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC20H4.07 Entrez Gene
WikiGene2542007RecA family ATPase Rhp57
Uniprot_genenameRHP57
EntrezGene2542007RecA family ATPase Rhp57
SPD / RIKEN50/50D04Orfeome Localization Data
UniProtKB/SwissProtQ9UUL2DNA repair protein rhp57
ModBaseQ9UUL2Database of comparative protein structure models
Pfam Protein DomainsQ9UUL2Pfam Domain Arrangement
RefSeq PeptideNP_593627RecA family ATPase Rhp57
RefSeq mRNANM_001019058972h- RecA family ATPase Rhp57 (rhp57), mRNA
European Nucleotide ArchiveBAA83768ENA Protein Mapping
European Nucleotide ArchiveCAC19737ENA Protein Mapping
SPD / RIKEN50/50D04Orfeome Localization Data

Literature for rad57
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Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013