pcr1 (SPAC21E11.03c)

Gene Standard Namepcr1 ChromosomeI
Systematic IDSPAC21E11.03c Gene Start4253622
Synonymsmts2 Gene End4252142
Producttranscription factor Pcr1 Gene Length1481
Feature Typeprotein coding CDS Start4252918
Name Description CDS End4252403
Characterisation Statuspublished CDS Length516

Ensembl Gene Location
  1. SPAC1F7.11c
  2. yak3
  3. rpl801
  4. pcr1
  5. aca1
  6. cyp8
  7. tif224
  8. prl13
  9. SPAC21E11.07
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0000054abnormal microtubule cytoskeleton organizationnot recorded (overexpression)unknownPMID:15797925
FYPO:0002060viable vegetative cell populationMicroscopypcr1delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIDAPMID:15448137
has_direct_input m26_siteIDAPMID:15448137
IDAPMID:8557039
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
happens_during cellular response to cadmium ion, has_regulation_target ntp1IMPPMID:15164362
GO:0003677DNA bindingIDAPMID:7958849
GO:0003723RNA bindingIDAPMID:7518718
GO:0010844recombination hotspot bindingIDAPMID:7958849
GO:0043565sequence-specific DNA bindingIDAPMID:7958849
GO:0046982protein heterodimerization activityIPIatf1PMID:7958849
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0006355regulation of transcription, DNA-dependentICGO:0000978GO_REF:0000001
GO:0006995cellular response to nitrogen starvationIMPPMID:15448137
GO:0007131reciprocal meiotic recombinationIMPPMID:9391101
GO:0010847regulation of chromatin assemblyIMPPMID:14988732
GO:0010848regulation of chromatin disassemblyIMPPMID:15448137
GO:0031060regulation of histone methylationIMPPMID:15218150
GO:0035065regulation of histone acetylationIMPPMID:14988732
GO:0043949regulation of cAMP-mediated signalingIMPPMID:15448137
GO:0051039positive regulation of transcription during meiosisIDAPMID:8552099
GO:1900391regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter
has_regulation_target cgs2IMPPMID:15448137
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0000790nuclear chromatinNASGO_REF:0000001
GO:0005634nucleusIDAPMID:16823372
GO:0005819spindleIDAPMID:16823372
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
142536224252142

References

Region Start End Reference
five_prime_UTR42536224252919PMID:21511999
five_prime_UTR42536224252919PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF00170 IPR004827 Pfam Basic-leucine zipper domain 12 69 5
SM00338 IPR004827 SMART Basic-leucine zipper domain 8 72 5
PS00036 IPR004827 Prosite Patterns Basic-leucine zipper domain 15 30 5
PS50217 IPR004827 Prosite Profiles Basic-leucine zipper domain 10 73 6
G3DSA:1.20.5.170 Gene3D 5 74 7
SSF57959 SuperFamily 12 72 6
PTHR19304 hmmpanther 7 79 4
Coil ncoils Rabaptin coiled-coil domain 35 70 974

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceAll Genes
PBO:0000545bZIP (basic leucine zipper) transcription factor familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000545
PBO:0002433Atf-CREB subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0002433

Protein Properties

Ave. residue weight 113.15 Da
Charge 11.50
Isoelectric point 10.53
Molecular weight 19.35 kDa
Number of residues 171
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
deletion mutant expression profiling PMID:18252721
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1798.96PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2609.25PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.69PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.5PMID:23101633
Subunit Composition
DescriptionQualifierReference
homodimeric PMID:7958849
heterodimeric PMID:7958849
Pathway
DescriptionQualifierReference
links stress-activated MAPK (Sty1) pathway to cAMP-dependent protein kinase (Pka1) pathway PMID:15448137
Species Distribution
DescriptionQualifierReference
orthologs cannot be distinguished
conserved in fungi
conserved in eukaryotes
conserved in eukaryotes only
Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
atf1transcription factor, Atf-CREB family Atf1 Dosage RescuePMID:10102365
Phenotypic EnhancementPMID:18375616
ago1argonaute Phenotypic EnhancementPMID:15218150
tup11transcriptional corepressor Tup11 Phenotypic SuppressionPMID:11238405
dcr1dicer Phenotypic EnhancementPMID:15218150
Synthetic Growth DefectPMID:15475954
tup12transcriptional corepressor Tup12 Phenotypic SuppressionPMID:11238405
deb1transcription factor Deb1/Rdp1 Phenotypic EnhancementPMID:15218150
sla1La protein homolog Synthetic RescuePMID:22160596
sre2membrane-tethered transcription factor (predicted) Positive GeneticPMID:21504829
ers1RNA-silencing factor Ers1 Phenotypic EnhancementPMID:22733737
chp1chromodomain protein Chp1 Synthetic Growth DefectPMID:15475954
tas3RITS complex subunit 3 Synthetic Growth DefectPMID:15475954
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
atf1transcription factor, Atf-CREB family Atf1 Affinity Capture-RNAPMID:22144913
Affinity Capture-WesternPMID:9135083
Affinity Capture-WesternPMID:18375616
swi6HP1 family chromodomain protein Swi6 Affinity Capture-WesternPMID:15292231
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
Contact Curators
External References
Database Identifier Description
NBRP SPAC21E11.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC21E11.03c Retrieval of eukaryotic orthologs
BioGrid SPAC21E11.03c BioGRID Interaction Datasets
Bähler Lab SPAC21E11.03c Cell Cycle Expression Profile
Bähler Lab SPAC21E11.03c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC21E11.03c Pheromone response/mating expression profiles
Bähler Lab SPAC21E11.03c Environmental stress expression profiles
Bähler Lab SPAC21E11.03c Bähler Lab Transcriptome Viewer
Cyclebase SPAC21E11.03c Cell Cycle Data
PInt SPAC21E11.03c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC21E11.03c Entrez Gene
WikiGene2542047transcription factor Pcr1
Uniprot_genenamePCR1
EntrezGene2542047transcription factor Pcr1
SPD / RIKEN05/05A11Orfeome Localization Data
UniProtKB/SwissProtQ09926Transcription factor pcr1
ModBaseQ09926Database of comparative protein structure models
Pfam Protein DomainsQ09926Pfam Domain Arrangement
RefSeq PeptideNP_594500transcription factor Pcr1
RefSeq mRNANM_001019929972h- transcription factor Pcr1 (pcr1), mRNA
European Nucleotide ArchiveAAB46991ENA Protein Mapping
European Nucleotide ArchiveBAA09818ENA Protein Mapping
European Nucleotide ArchiveCAA91968ENA Protein Mapping
UniParcUPI000013144DUniProt Archive

Literature for pcr1
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013