tim10 (SPAC222.03c)


Gene Standard Nametim10 Characterisation Statusbiological_role_inferred
Systematic IDSPAC222.03c Feature Typeprotein coding
Synonyms Name Description
ProductTim9-Tim10 complex subunit Tim10 (predicted) Product Size89aa, 10.19 kDa
Genomic Location Chromosome I, 948800-947876 (925nt); CDS:948581-947964 (618nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
metal ion binding743
Annotation ExtensionEvidenceWith/FromReference
protein transporter activity41
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
protein import into mitochondrial inner membrane12
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosol2314
Annotation ExtensionEvidenceWith/FromReference
mitochondrial intermembrane space30
Annotation ExtensionEvidenceWith/FromReference
mitochondrial intermembrane space protein transporter complex4
Annotation ExtensionEvidenceWith/FromReference
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationtim10ΔNull1438

Cell Phenotype

Term NameAlleleExpressionCount
inviable tapered vegetative celltim10ΔNull134
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons948800..948481, 948132..947876
mRNA948800..947876
5' UTR948800..948582PMID:21511999
CDS948581..948481, 948132..947964
3' UTR947963..947876PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02953 Pfam IPR004217 Tim10/DDP family zinc finger 16 82 4
PTHR11038 HMMPANTHER IPR027247 Mitochondrial import inner membrane translocase subunit Tim10/Tim12 2 86 1
PTHR11038:SF16 HMMPANTHER IPR027100 Mitochondrial import inner membrane translocase subunit Tim10 2 86 1
1.10.287.810 Gene3D IPR004217 Tim10/DDP family zinc finger 20 82 4
SSF144122 SuperFamily IPR004217 Tim10/DDP family zinc finger 24 85 4

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000679zf-Tim10/DDP typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000679

Protein Properties

Ave. residue weight 114.55 Da
Charge 1.00
Isoelectric point 7.29
Molecular weight 10.19 kDa
Number of residues 89
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
109077during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
125110during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
118090during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
106329during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
104941during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
11620.39during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
4181.85during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.2during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.42during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC222.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC222.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC222.03c BioGRID Interaction Datasets
Expression Viewer SPAC222.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC222.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC222.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC222.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC222.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC222.03c Transcriptome Viewer (Bähler Lab)
GEO SPAC222.03c GEO profiles
PInt SPAC222.03c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC222.03c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC222.03c Fission yeast phenotypic data & analysis
Cyclebase SPAC222.03c.1 Cell Cycle Data
SPD / RIKEN06/06H11Orfeome Localization Data
UniProtKB/SwissProtQ9UTE9Mitochondrial import inner membrane translocase subunit tim10
ModBaseQ9UTE9Database of comparative protein structure models
STRINGQ9UTE9Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593142Tim9-Tim10 complex subunit Tim10 (predicted)
RefSeq mRNANM_001018539972h- Tim9-Tim10 complex subunit Tim10 (predicted) (tim10), mRNA
European Nucleotide ArchiveCAB60695.1ENA Protein Mapping
UniParcUPI000006A805UniProt Archive

Literature for tim10

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015