tim10 (SPAC222.03c)

Gene Standard Nametim10 Characterisation Statusbiological_role_inferred
Systematic IDSPAC222.03c Feature Typeprotein coding
Synonyms Name Description
ProductTim9-Tim10 complex subunit Tim10 (predicted) Product Size89aa, 10.19 kDa
Genomic Location Chromosome I, 948800-947876 (925nt); CDS:948581-947964 (618nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0046872metal ion bindingIEAUniProtKB-KW:KW-0479GO_REF:0000037747
GO:0008565protein transporter activity42
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0045039protein import into mitochondrial inner membraneISSUniProtKB:P87108GO_REF:000002412
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0005758mitochondrial intermembrane spaceISSUniProtKB:P87108GO_REF:000002426
GO:0042719mitochondrial intermembrane space protein transporter complexISSUniProtKB:P87108GO_REF:00000244
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002061inviable vegetative cell populationMicroscopytim10ΔNullPMID:204732891338
Microscopytim10ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002111inviable tapered vegetative cell134
expressivity FYPO_EXT:0000003
penetrance FYPO_EXT:0000001
Microscopytim10ΔNullPECO:0000137, PECO:0000005PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02953 Pfam IPR004217 Tim10/DDP family zinc finger 16 82 4
PTHR11038 HMMPANTHER IPR027247 Mitochondrial import inner membrane translocase subunit Tim10/Tim12 1 86 1
PTHR11038:SF8 HMMPANTHER IPR027100 Mitochondrial import inner membrane translocase subunit Tim10 1 86 1 Gene3D IPR004217 Tim10/DDP family zinc finger 20 82 4
SSF144122 SuperFamily IPR004217 Tim10/DDP family zinc finger 24 85 4

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000137zinc finger proteinTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000137
PBO:0000679zf-Tim10/DDP typeTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000679

Protein Properties

Ave. residue weight 114.55 Da
Charge 1.00
Isoelectric point 7.29
Molecular weight 10.19 kDa
Number of residues 89
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
109077during GO:0000080PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
125110during GO:0000084PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
118090during GO:0000085PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
106329during GO:0000087PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
11620.39during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
104941during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
4181.85during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.2during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
0.42during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4600
conserved in eukaryotes4514
conserved in metazoa3425
conserved in vertebrates3400
conserved in eukaryotes only2497

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC222.03c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC222.03c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC222.03c BioGRID Interaction Datasets
Expression Viewer SPAC222.03c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC222.03c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC222.03c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC222.03c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC222.03c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC222.03c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC222.03c Cell Cycle Data
GEO SPAC222.03c GEO profiles
PInt SPAC222.03c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC222.03c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC222.03c Fission yeast phenotypic data & analysis
SPD / RIKEN06/06H11Orfeome Localization Data
UniProtKB/SwissProtQ9UTE9Mitochondrial import inner membrane translocase subunit tim10
ModBaseQ9UTE9Database of comparative protein structure models
STRINGQ9UTE9Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593142Tim9-Tim10 complex subunit Tim10 (predicted)
RefSeq mRNANM_001018539972h- Tim9-Tim10 complex subunit Tim10 (predicted) (tim10), mRNA
European Nucleotide ArchiveCAB60695.1ENA Protein Mapping
UniParcUPI000006A805UniProt Archive

Literature for tim10

Search: Europe PMC or PubMed

Release Version: PomBase:23_47 - 27 Oct 2014