sno1 (SPAC222.08c)

Gene Standard Namesno1 Characterisation Statusbiological_role_inferred
Systematic IDSPAC222.08c Feature Typeprotein coding
Synonyms Name Description
Productglutamine aminotransferase subunit Sno1 (predicted) Product Size234aa, 25.90 kDa
Genomic Location Chromosome I, 958774-957367 (1408nt); CDS:958350-957646 (705nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
glutaminase activity1
Annotation ExtensionEvidenceWith/FromReference
transferase activity747
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
glutamine catabolic process3
Annotation ExtensionEvidenceWith/FromReference
pyridoxal phosphate biosynthetic process6
Annotation ExtensionEvidenceWith/FromReference
pyridoxine biosynthetic process3
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
Annotation ExtensionEvidenceWith/FromReference
glutaminase complex1
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to hydroxyurea518
expressivity FYPO_EXT:0000002sno1ΔNull
viable vegetative cell populationsno1ΔNull3781

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphology3092
penetrance FYPO_EXT:0000001sno1ΔNull
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Coordinates Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF01174 Pfam IPR002161 PdxT/SNO family 26 225 1
PS01236 Prosite Patterns IPR021196 PdxT/SNO family, conserved site 62 72 1
PS51130 Prosite Profiles IPR002161 PdxT/SNO family 23 226 1
PTHR31559 HMMPANTHER 12 234 1 Gene3D IPR029062 Class I glutamine amidotransferase-like 22 224 20
SSF52317 SuperFamily IPR029062 Class I glutamine amidotransferase-like 23 224 21
PIRSF005639 PIRSF IPR002161 PdxT/SNO family 21 230 1
TIGR03800 tigrfam IPR002161 PdxT/SNO family 23 223 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 110.69 Da
Charge -5.00
Isoelectric point 5.13
Molecular weight 25.90 kDa
Number of residues 234
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0034599expression microarray evidencePMID:12529438

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
40726during GO:0000084PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
31286during GO:0000087PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
15768.51during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
37822during GO:0072690PECO:0000126,
single cellmass spectrometry evidencePMID:24763107
4402.01during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3.1during GO:0072690PECO:0000005,
population wideexperimental evidencePMID:23101633
0.55during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population wideexperimental evidencePMID:23101633
Species Distribution
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000

Manually curated orthologous groups


Orthologs in Compara

Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
hhp1serine/threonine protein kinase Hhp1 Affinity Capture-MSPMID:24055157
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
sno1glutamine aminotransferase subunit Sno1 (predicted) Two-hybridPMID:23695164
snz1pyridoxine biosynthesis protein Two-hybridPMID:23695164
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
ams2cell cycle regulated GATA-type transcription factor Ams2 Positive GeneticPMID:22681890
cut3condensin complex subunit Cut3 Positive GeneticPMID:22681890
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
snu66U4/U6 x U5 tri-snRNP complex subunit Snu66 Negative GeneticPMID:22681890
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:22681890
rhb1Rheb GTPase Rhb1 Positive GeneticPMID:22681890
set1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
SPCC550.15cribosome biogenesis protein (predicted) Negative GeneticPMID:22681890
set6histone lysine methyltransferase Set6 (predicted) Negative GeneticPMID:22681890
pyp1tyrosine phosphatase Pyp1 Negative GeneticPMID:22681890
SPAC644.09alanine racemase (predicted) Negative GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Positive GeneticPMID:22681890
xap5xap-5-like protein Positive GeneticPMID:24957674
swd1Set1C complex subunit Swd1 Positive GeneticPMID:22681890
lub1WD repeat protein Lub1 Positive GeneticPMID:22681890
elp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
SPCC11E10.07ctranslation initiation factor eIF2B alpha subunit (predicted) Negative GeneticPMID:22681890
res1MBF transcription factor complex subunit Res1 Negative GeneticPMID:22681890
ckb2CK2 family regulatory subunit Ckb2 (predicted) Negative GeneticPMID:22681890
nup60nucleoporin Nup60 Negative GeneticPMID:22681890
dad3DASH complex subunit Dad3 Negative GeneticPMID:22681890
mbx1MADS-box transcription factor Mbx1 Negative GeneticPMID:22681890
hus1checkpoint clamp complex protein Hus1 Positive GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
dad4DASH complex subunit Dad4 Negative GeneticPMID:22681890
pst2Clr6 histone deacetylase complex subunit Pst2 Negative GeneticPMID:22681890
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Negative GeneticPMID:22681890
gcn20AAA family ATPase Gcn20 (predicted) Negative GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:22681890
dad2DASH complex subunit Dad2 Negative GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Positive GeneticPMID:22681890
mmb1mitochondrial microtubule binder Mmb1 Negative GeneticPMID:22681890
SPBC17A3.06phosphoprotein phosphatase (predicted) Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
pob3FACT complex subunit Pob3 Negative GeneticPMID:22681890
arp42SWI/SNF and RSC complex subunit Arp42 Negative GeneticPMID:22681890
ypa1protein phosphatase type 2A regulator, PTPA family Ypa1 Negative GeneticPMID:22681890
sdc1Dpy-30 domain protein Sdc1 Negative GeneticPMID:22681890
srb10cyclin-dependent protein Srb mediator subunit kinase Srb10 Positive GeneticPMID:22681890
psl1cyclin pho85 family Psl1 (predicted) Positive GeneticPMID:22681890
rga2Rho-type GTPase activating protein Rga2 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:22681890
usp102U1 snRNP-associated protein Usp102 Negative GeneticPMID:22681890
met14adenylyl-sulfate kinase (predicted) Positive GeneticPMID:22681890
gma12alpha-1,2-galactosyltransferase Gma12 Negative GeneticPMID:22681890
sif1Sad1 interacting factor 1 Positive GeneticPMID:22681890
bob1prefoldin subunit 5 (predicted) Positive GeneticPMID:22681890
php3CCAAT-binding factor complex subunit Php3 Positive GeneticPMID:22681890
SPCC18.10pyridoxine-pyridoxal-pyridoxamine kinase (predicted) Negative GeneticPMID:22681890
med7mediator complex subunit Med7 Negative GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
sac12inositol polyphosphate phosphatase (predicted) Negative GeneticPMID:22681890
ssp2serine/threonine protein kinase Ssp2 Positive GeneticPMID:22681890
SPAC17H9.13cglutamate 5-kinase (predicted) Negative GeneticPMID:22681890
exo1exonuclease I Exo1 Positive GeneticPMID:22681890
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Positive GeneticPMID:22681890
prw1Clr6 histone deacetylase complex subunit Prw1 Negative GeneticPMID:22681890
ppm1leucine carboxyl methyltransferase Ppm1 (predicted) Positive GeneticPMID:22681890
SPAC13G7.12ccholine kinase (predicted) Positive GeneticPMID:22681890
dap1cytochrome P450 regulator Dap1 Negative GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
mlh1MutL family protein Mlh1 (predicted) Positive GeneticPMID:22681890
gcn2eIF2 alpha kinase Gcn2 Negative GeneticPMID:22681890
fft3SMARCAD1 family ATP-dependent DNA helicase Fft3 Negative GeneticPMID:22681890
rnc1RNA-binding protein that suppresses calcineurin deletion Rnc1 Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
spc19DASH complex subunit Spc19 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC222.08c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC222.08c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC222.08c BioGRID Interaction Datasets
Expression Viewer SPAC222.08c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC222.08c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC222.08c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC222.08c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC222.08c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC222.08c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC222.08c Cell Cycle Data
GEO SPAC222.08c GEO profiles
PInt SPAC222.08c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC222.08c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC222.08c Fission yeast phenotypic data & analysis
SPD / RIKEN08/08C08Orfeome Localization Data
UniProtKB/SwissProtQ9UTE4Uncharacterized glutamine amidotransferase C222.08c
ModBaseQ9UTE4Database of comparative protein structure models
STRINGQ9UTE4Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593147glutamine aminotransferase subunit
RefSeq mRNANM_001018544972h- glutamine aminotransferase subunit (SPAC222.08c), mRNA
European Nucleotide ArchiveCAB60700.1ENA Protein Mapping
UniParcUPI000006B729UniProt Archive

Literature for sno1

Search: Europe PMC or PubMed

Release Version: PomBase:25_48 - 10 Jan 2015