meu13 (SPAC222.15)

Gene Standard Namemeu13 ChromosomeI
Systematic IDSPAC222.15 Gene Start977709
SynonymsSPAC821.01 Gene End978637
ProductTat binding protein 1(TBP-1)-interacting protein (TBPIP) homolog (predicted) Gene Length929
Feature Typeprotein coding CDS Start977709
Name DescriptionMeiotic Expression Upregulated CDS End978637
Characterisation Statuspublished CDS Length929

Ensembl Gene Location
  1. SPAC222.13c
  2. SPNCRNA.701
  3. SPAC222.14c
  4. prl50
  5. meu13
  6. SPAC222.18
  7. csn3
  8. SPAC821.03c
  9. cid13
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopymeu13delta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0005515protein bindingIPImcp7GO_REF:0000001
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0007129synapsisIMPPMID:11447128
GO:0007131reciprocal meiotic recombinationIMPPMID:11447128
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000790nuclear chromatin
exists_during meiotic cell cycleNASGO_REF:0000001
GO:0005634nucleusIDAPMID:16823372
GO:0005819spindleIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0044732mitotic spindle pole bodyIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1977709977757
2977804977857
3977905978006
4978049978189
5978333978637
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF07106 IPR010776 Pfam Tat binding protein 1-interacting 16 184 1
G3DSA:1.10.10.10 IPR011991 Gene3D 8 104 43
Coil ncoils Rabaptin coiled-coil domain 133 154 974
Coil ncoils Rabaptin coiled-coil domain 82 110 974
PTHR15938 IPR010776 hmmpanther Tat binding protein 1-interacting 1 215 1

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReference
SO:0001080coiled_coil

Protein Properties

Ave. residue weight 114.22 Da
Charge 1.00
Isoelectric point 7.41
Molecular weight 24.67 kDa
Number of residues 216
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
expressed during meiosis PMID:16303567
meiosis-specific splicing PMID:15893732
protein levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000005,
PECO:0000014		population_widePMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.026PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide0.16PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
amk2AMP-activated protein kinase beta subunit Amk2 Positive GeneticPMID:18818364
rad4BRCT domain protein Rad4 Phenotypic EnhancementPMID:14718568
Phenotypic Suppression
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:18818364
atg18WD repeat protein involved in autophagy Atg18a Positive GeneticPMID:18818364
cdm1DNA polymerase delta subunit Cdm1 Negative GeneticPMID:18818364
rad17RFC related checkpoint protein Rad17 Phenotypic EnhancementPMID:12032093
rpl160160S ribosomal protein L13/L16 (predicted) Negative GeneticPMID:18818364
sdh4TIM22 inner membrane protein import complex anchor subunit Tim18 Negative GeneticPMID:18818364
SPCC126.01cconserved fungal protein Positive GeneticPMID:18818364
cds1replication checkpoint kinase Cds1 Phenotypic EnhancementPMID:12032093
tma23ribosome biogenesis protein Tma23 (predicted) Negative GeneticPMID:18818364
stp1protein tyrosine phosphatase Stp1 Positive GeneticPMID:18818364
rad3ATR checkpoint kinase Rad3 Phenotypic EnhancementPMID:12032093
rsc4RSC complex subunit Rsc4 Negative GeneticPMID:18818364
tip1CLIP170 family protein Tip1 Negative GeneticPMID:18818364
pnn1pinin ortholog, involved in splicing Pnn1 (predicted) Negative GeneticPMID:18818364
SPAC1093.03inositol polyphosphate phosphatase (predicted) Positive GeneticPMID:18818364
mug154conserved fungal protein Negative GeneticPMID:18818364
pus1tRNA pseudouridine synthase Lsp1 Positive GeneticPMID:18818364
rec12endonuclease Rec12 Phenotypic SuppressionPMID:12482912
mek1Cds1/Rad53/Chk2 family protein kinase Mek1 Phenotypic EnhancementPMID:12032093
Phenotypic SuppressionPMID:12482912
mcp7meiosis specific coiled-coil protein Mcp7 Phenotypic EnhancementPMID:15210864
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
mcp7meiosis specific coiled-coil protein Mcp7 Affinity Capture-WesternPMID:15210864
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External References
Database Identifier Description
NBRP SPAC222.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC222.15 Retrieval of eukaryotic orthologs
BioGrid SPAC222.15 BioGRID Interaction Datasets
Bähler Lab SPAC222.15 Cell Cycle Expression Profile
Bähler Lab SPAC222.15 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC222.15 Pheromone response/mating expression profiles
Bähler Lab SPAC222.15 Environmental stress expression profiles
Bähler Lab SPAC222.15 Bähler Lab Transcriptome Viewer
Cyclebase SPAC222.15 Cell Cycle Data
PInt SPAC222.15 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC222.15 Entrez Gene
SPD / RIKEN13/13A01Orfeome Localization Data
WikiGene3361533homologous-pairing protein 2
Uniprot_genenameMEU13
EntrezGene3361533homologous-pairing protein 2
UniProtKB/SwissProtQ9HGK2Homologous-pairing protein 2
ModBaseQ9HGK2Database of comparative protein structure models
Pfam Protein DomainsQ9HGK2Pfam Domain Arrangement
RefSeq PeptideNP_001018191homologous-pairing protein 2
RefSeq mRNANM_001018551972h- homologous-pairing protein 2 (meu13), mRNA
European Nucleotide ArchiveBAB17055ENA Protein Mapping
European Nucleotide ArchiveCAD33796ENA Protein Mapping
UniParcUPI000012EE93UniProt Archive

Literature for meu13
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013