ogm1 (SPAC22A12.07c)

Gene Standard Nameogm1 Characterisation Statuspublished
Systematic IDSPAC22A12.07c Feature Typeprotein coding
Synonymsoma1 Name DescriptionO-glycoside mannosyltransferase
Productprotein O-mannosyltransferase Ogm1 Product Size893aa, 101.34 kDa
Genomic Location Chromosome I, 1169743-1166562 (3182nt); CDS:1169503-1166822 (2682nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0004169dolichyl-phosphate-mannose-protein mannosyltransferase activity3
has substrate wsc1IDAPMID:15948957
GO:0046982protein heterodimerization activityIPIogm4PMID:1594895761
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0000917barrier septum assemblyIMPPMID:1594895712
GO:0000032cell wall mannoprotein biosynthetic processIMPPMID:1594895710
GO:0035269protein O-linked mannosylationIGIwsc1PMID:159489574
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0031502dolichyl-phosphate-mannose-protein mannosyltransferase complexIDAPMID:159489573
GO:0012505endomembrane systemIDAPMID:15809069962
GO:0005789endoplasmic reticulum membraneIDAPMID:15809069207
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002642sensitive to amphotericin BCell growth assayogm1ΔNullPECO:0000137, PECO:0000005PMID:2373802169
expressivity FYPO_EXT:0000003
FYPO:0002641sensitive to micafunginCell growth assayogm1ΔNullPECO:0000137, PECO:0000005PMID:23738021105
expressivity FYPO_EXT:0000002
FYPO:0002060viable vegetative cell populationMicroscopyogm1ΔNullPECO:0000005, PECO:0000137PMID:236978063755

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001510viable vegetative cell, abnormal cell shape, normal cell sizeMicroscopyogm1ΔNullPECO:0000005, PECO:0000137PMID:23697806215
penetrance FYPO_EXT:0000001
Ensembl transcript structure with UTRs, exons and introns


Exon Start End


Region Start End Reference
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02366 Pfam IPR003342 Glycosyl transferase, family 39 39 282 3
PF02815 Pfam IPR016093 MIR motif 329 504 3
SM00472 SMART IPR016093 MIR motif 310 364 3
SM00472 SMART IPR016093 MIR motif 374 433 3
SM00472 SMART IPR016093 MIR motif 444 499 3
TMhelix TMHMM 121 143 959
TMhelix TMHMM 572 594 959
TMhelix TMHMM 170 192 959
TMhelix TMHMM 636 658 959
TMhelix TMHMM 29 47 959
TMhelix TMHMM 222 244 959
TMhelix TMHMM 257 279 959
TMhelix TMHMM 199 218 959
TMhelix TMHMM 607 626 959
TMhelix TMHMM 671 688 959
PS50919 Prosite Profiles IPR016093 MIR motif 443 499 3
PS50919 Prosite Profiles IPR016093 MIR motif 310 364 3
PS50919 Prosite Profiles IPR016093 MIR motif 374 433 3
PTHR10050:SF12 HMMPANTHER IPR027004 1 719 1
PTHR10050 HMMPANTHER IPR027005 Glycosyltransferase 39 like 1 719 3
G3DSA: Gene3D 309 506 6
SSF82109 SuperFamily IPR016093 309 497 3
Coil ncoils Rabaptin coiled-coil domain 780 805 975
Low complexity (SEG) seg 781 826
Low complexity (SEG) seg 853 864

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0000808PMT familyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000808
PBO:0000809PMT1 subfamilyTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0000809

Sequence Ontology

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 113.48 Da
Charge -3.00
Isoelectric point 6.34
Molecular weight 101.34 kDa
Number of residues 893
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
5959.2during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
9831.27during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
7.1during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
1.6during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3080
conserved in fungi4564
conserved in eukaryotes4482
conserved in metazoa3419
conserved in vertebrates3394
conserved in eukaryotes only2485

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ogm4protein O-mannosyltransferase Ogm4 Synthetic LethalityPMID:15948957
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
ogm2protein O-mannosyltransferase Ogm2 Affinity Capture-WesternPMID:15948957
hhp2serine/threonine protein kinase Hhp2 Affinity Capture-MSPMID:24055157
paa1protein phosphatase regulatory subunit Paa1 Affinity Capture-MSPMID:22119525
External References
Database Identifier Description
NBRP SPAC22A12.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC22A12.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC22A12.07c BioGRID Interaction Datasets
Expression Viewer SPAC22A12.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC22A12.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC22A12.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC22A12.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC22A12.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC22A12.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC22A12.07c Cell Cycle Data
GEO SPAC22A12.07c GEO profiles
PInt SPAC22A12.07c Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz2.4.1.109Integrated relational Enzyme database
Rhea2.4.1.109Annotated reactions database
SPD / RIKEN47/47B01Orfeome Localization Data
WikiGene2541418protein O-mannosyltransferase Ogm1
EntrezGene2541418protein O-mannosyltransferase Ogm1
UniProtKB/SwissProtO13898Dolichyl-phosphate-mannose--protein mannosyltransferase 1
ModBaseO13898Database of comparative protein structure models
StringO13898Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593237protein O-mannosyltransferase Ogm1
RefSeq mRNANM_001018634972h- protein O-mannosyltransferase Ogm1 (ogm1), mRNA
European Nucleotide ArchiveCAB16577ENA Protein Mapping
UniParcUPI0000131D0CUniProt Archive

Literature for ogm1

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014