mug84 (SPAC22A12.13)


Gene Standard Namemug84 Characterisation Statusbiological_role_inferred
Systematic IDSPAC22A12.13 Feature Typeprotein coding
Synonyms Name DescriptionMeiotically Upregulated Gene
Productpig-P subunit (predicted) Product Size195aa, 22.26 kDa
Genomic Location Chromosome I, 1180184-1181157 (974nt); CDS:1180254-1180841 (588nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
phosphatidylinositol N-acetylglucosaminyltransferase activity5
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
GPI anchor biosynthetic process28
Annotation ExtensionEvidenceWith/FromReference
meiotic cell cycle425
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Population Phenotype

Term NameAlleleExpressionCount
inviable vegetative cell populationmug84ΔNull1435

Cell Phenotype

Term NameAlleleExpressionCount
inviable after spore germination, single or double cell divisionmug84ΔNull102
inviable after spore germination, without cell division, with abnormal germ tube morphologymug84ΔNull153
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons1180184..1181157
mRNA1180184..1181157
5' UTR1180184..1180253PMID:21511999
CDS1180254..1180841
3' UTR1180842..1181157PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08510 Pfam IPR013717 PIG-P 80 178 1
TMhelix TMHMM 121 143 959
TMhelix TMHMM 84 106 959
PTHR21726 HMMPANTHER 13 189 2

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0000418signal_peptide279
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 114.17 Da
Charge -11.00
Isoelectric point 4.36
Molecular weight 22.26 kDa
Number of residues 195
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.3during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.31during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Warning
DescriptionQualifierReferenceCount
gene structure updated PMID:21511999432
Species Distribution
DescriptionQualifierReferenceCount
predominantly single copy (one to one)3092
conserved in fungi4604
conserved in eukaryotes4516
conserved in metazoa3430
conserved in vertebrates3405
conserved in eukaryotes only2502
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


External References
Database Identifier Description
NBRP SPAC22A12.13 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC22A12.13 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC22A12.13 BioGRID Interaction Datasets
Expression Viewer SPAC22A12.13 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC22A12.13 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC22A12.13 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC22A12.13 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC22A12.13 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC22A12.13 Transcriptome Viewer (Bähler Lab)
GEO SPAC22A12.13 GEO profiles
PInt SPAC22A12.13 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC22A12.13 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC22A12.13 Fission yeast phenotypic data & analysis
Cyclebase SPAC22A12.13.1 Cell Cycle Data
SPD / RIKEN42/42B07Orfeome Localization Data
UniProtKB/SwissProtO13904Meiotically up-regulated gene 84 protein
ModBaseO13904Database of comparative protein structure models
STRINGO13904Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593243pig-P subunit (predicted)
RefSeq mRNANM_001018640972h- pig-P subunit (predicted) (mug84), mRNA
European Nucleotide ArchiveCAB16583.3ENA Protein Mapping
KEGG_Enzyme00563+2.4.1.198Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
UniParcUPI000228F47AUniProt Archive
UniPathwayUPA00196Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis

Literature for mug84

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015