mug84 (SPAC22A12.13)

Gene Standard Namemug84 Characterisation Statusbiological role inferred
Systematic IDSPAC22A12.13 Feature Typeprotein coding
Synonyms Name DescriptionMeiotically Upregulated Gene
Productpig-P subunit (predicted) Product Size195aa, 22.26 kDa
Genomic Location Chromosome I, 1180184-1181157 (974nt); CDS:1180254-1180841 (588nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
phosphatidylinositol N-acetylglucosaminyltransferase activity5
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
GPI anchor biosynthetic process28
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Inviable

Single-allele Phenotypes

Population Phenotype

Term NameGenotypesCount
inviable vegetative cell populationmug84Δ1443

Cell Phenotype

Term NameGenotypesCount
inviable after spore germination, single or double cell divisionmug84Δ105
inviable after spore germination, without cell division, with abnormal germ tube morphologymug84Δ153
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
5' UTR1180184..1180253PMID:21511999
3' UTR1180842..1181157PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08510 Pfam IPR013717 PIG-P 81 189 1
TMhelix TMHMM 84 106 959
TMhelix TMHMM 121 143 959
PTHR21726 HMMPANTHER 13 189 2

View domain organization at Pfam

Term IDTerm NameReferenceCount

Protein Properties

Ave. residue weight 114.17 Da
Charge -11.00
Codon Adpatation Index 0.39
Isoelectric point 4.36
Molecular weight 22.26 kDa
Number of residues 195
Gene Expression

Qualitative Gene Expression

RNA levelincreased during GO:0051321experimental evidencePMID:16303567

Quantitative Gene Expression

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1.3during GO:0072690PECO:0000014,
population wideexperimental evidencePMID:23101633
0.31during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
population wideexperimental evidencePMID:23101633
gene structure updated PMID:21511999433
Taxonomic Conservation
predominantly single copy (one to one)3090
conserved in fungi4604
conserved in eukaryotes4514
conserved in metazoa3421
conserved in vertebrates3396
conserved in eukaryotes only2503

Manually curated orthologous groups


Orthologs in Compara

External References
Database Identifier Description
NBRP SPAC22A12.13 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC22A12.13 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC22A12.13 BioGRID Interaction Datasets
Expression Viewer SPAC22A12.13 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC22A12.13 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC22A12.13 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC22A12.13 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC22A12.13 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC22A12.13 Transcriptome Viewer (Bähler Lab)
GEO SPAC22A12.13 GEO profiles
PInt SPAC22A12.13 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC22A12.13 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC22A12.13 Fission yeast phenotypic data & analysis
Cyclebase SPAC22A12.13.1 Cell Cycle Data
SPD / RIKEN42/42B07Orfeome Localization Data
UniProtKB/SwissProtO13904Meiotically up-regulated gene 84 protein
ModBaseO13904Database of comparative protein structure models
STRINGO13904Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593243pig-P subunit (predicted)
RefSeq mRNANM_001018640972h- pig-P subunit (predicted) (mug84), mRNA
European Nucleotide ArchiveCU329670ENA EMBL mapping
European Nucleotide ArchiveCAB16583ENA Protein Mapping
European Nucleotide ArchiveCAB16583.3ENA Protein Mapping
KEGG00563+ biosynthesis
UniParcUPI000228F47AUniProt Archive
UniPathwayUPA00196Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis

Literature for mug84

Search: Europe PMC or PubMed

Release Version: PomBase:28_55 - 09 Sep 2015