Gene Standard NameUnassigned Characterisation Statusbiological_role_inferred
Systematic IDSPAC23A1.17 Feature Typeprotein coding
Synonyms Name Description
ProductWIP family cytoskeletal protein (predicted) Product Size1611aa, 170.53 kDa
Genomic Location Chromosome I, 4106702-4112044 (5343nt); CDS:4106827-4111662 (4836nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0017024myosin I bindingISOSGD:S000003557GO_REF:00000241
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030036actin cytoskeleton organizationISOSGD:S000003557GO_REF:000002495
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030479actin cortical patchISOSGD:S000003557GO_REF:000002447
GO:0032153cell division siteIDAPMID:16823372298
GO:0051286cell tipIDAPMID:16823372192
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopySPAC23A1.17ΔNullPECO:0000005, PECO:0000137PMID:236978063751

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001MicroscopySPAC23A1.17ΔNullPECO:0000005, PECO:0000137PMID:23697806
Ensembl transcript structure with UTRs, exons and introns


Exon Start End
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00018 Pfam IPR001452 Src homology-3 domain 9 58 18
SM00326 SMART IPR001452 Src homology-3 domain 6 66 21
PS50002 Prosite Profiles IPR001452 Src homology-3 domain 3 67 21 Gene3D 4 64 21
SSF50044 SuperFamily IPR001452 Src homology-3 domain 3 67 21
Coil ncoils Rabaptin coiled-coil domain 398 419 968

View domain organization at Pfam

Protein Properties

Ave. residue weight 105.85 Da
Charge -20.00
Isoelectric point 5.61
Molecular weight 170.53 kDa
Number of residues 1611

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
present during mitotic M phase
present during mitotic M phaseS153PMID:21712547
present during mitotic M phaseS692PMID:21712547
present during mitotic M phaseS343PMID:21712547
present during mitotic M phaseS777PMID:21712547
present during mitotic M phaseS155PMID:21712547
present during mitotic M phaseS768PMID:21712547
present during mitotic M phaseS678PMID:21712547
level fluctuates during mitotic cell cycleS712PMID:24763107
present during mitotic M phaseS959PMID:21712547
present during mitotic M phaseS1003PMID:21712547
present during mitotic M phaseS916PMID:21712547
present during mitotic M phaseS699PMID:21712547
present during mitotic M phaseS712PMID:21712547
present during mitotic M phaseS718PMID:21712547
present during mitotic M phaseS589PMID:21712547
present during mitotic M phaseS501PMID:21712547
present during mitotic M phaseS682PMID:21712547
present during mitotic M phaseS597PMID:21712547
level fluctuates during mitotic cell cycleT715PMID:24763107
present during mitotic M phaseT1002PMID:21712547
present during mitotic M phaseT579PMID:21712547
present during mitotic M phaseT715PMID:21712547
present during mitotic M phaseT587PMID:21712547
present during mitotic M phaseT685PMID:21712547
present during mitotic M phaseT775PMID:21712547
present during mitotic M phaseT336PMID:21712547
present during mitotic M phaseT748PMID:21712547
MOD:00696phosphorylated residueNASPMID:195477441922
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
13937during GO:0000080PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
13956during GO:0000084PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
14614during GO:0000085PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
14504during GO:0000087PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
14514during GO:0072690PECO:0000126,
single_cellmass spectrometry evidencePMID:24763107
9392.78during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
11904.43during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
9.2during GO:0072690PECO:0000005,
population_wideexperimental evidencePMID:23101633
2.5during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
population_wideexperimental evidencePMID:23101633
Species Distribution
predominantly single copy (one to one)3092
conserved in fungi4599
conserved in eukaryotes4514
conserved in eukaryotes only2498

Manually curated orthologous groups


Orthologs in Compara

Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
elp3elongator complex subunit Elp3 (predicted) Negative GeneticPMID:22681890
Phenotypic EnhancementPMID:19547744
tef101translation elongation factor EF-1 alpha Ef1a-a Negative GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Negative GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
epe1Jmjc domain chromatin associated protein Epe1 Affinity Capture-MSPMID:24013502
cyk3cytokinesis protein Cyk3 (predicted) Affinity Capture-MSPMID:20603077
External References
Database Identifier Description
NBRP SPAC23A1.17 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC23A1.17 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC23A1.17 BioGRID Interaction Datasets
Expression Viewer SPAC23A1.17 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC23A1.17 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC23A1.17 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC23A1.17 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC23A1.17 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC23A1.17 Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC23A1.17 Cell Cycle Data
GEO SPAC23A1.17 GEO profiles
PInt SPAC23A1.17 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC23A1.17 Peptides identified in tandem mass spectrometry proteomics experiments
SPD / RIKEN48/48G09Orfeome Localization Data
UniProtKB/SwissProtO42854SH3 domain-containing protein C23A1.17
ModBaseO42854Database of comparative protein structure models
STRINGO42854Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_594446SH3 domain-containing protein
RefSeq mRNANM_001019875972h- SH3 domain-containing protein (SPAC23A1.17), mRNA
European Nucleotide ArchiveCAA16991.1ENA Protein Mapping
UniParcUPI0000069573UniProt Archive

Literature for SPAC23A1.17

Search: Europe PMC or PubMed

Release Version: PomBase:23_46 - 30 Aug 2014