rps23 (SPAC23C11.02c)


Gene Standard Namerps23 Characterisation Statusbiological_role_inferred
Systematic IDSPAC23C11.02c Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S23 (predicted) Product Size143aa, 15.66 kDa
Genomic Location Chromosome I, 2135841-2135328 (514nt); CDS:2135788-2135357 (432nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0003735structural constituent of ribosomeISOSGD:S000006336GO_REF:0000024255
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0002181cytoplasmic translationNASGO_REF:0000051445
GO:0006412translationISOSGD:S000006336GO_REF:0000024597
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0022627cytosolic small ribosomal subunitISOSGD:S000006336GO_REF:000002464
GO:0005730nucleolusIDAPMID:16823372355
GO:0005634nucleusIDAPMID:168233722740
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0001245sensitive to cobalt56
expressivity FYPO_EXT:0000003Cell growth assayrps23ΔNullPECO:0000201, PECO:0000005PMID:22806344
FYPO:0002060viable vegetative cell populationMicroscopyrps23ΔNullPECO:0000005, PECO:0000137PMID:236978063730
Microscopyrps23ΔNullPMID:20473289

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphology3088
penetrance FYPO_EXT:0000001Microscopyrps23ΔNullPECO:0000005, PECO:0000137PMID:23697806
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
121358412135328

UTRs

Region Coordinates Reference
five_prime_UTR2135841..2135789PMID:21511999
three_prime_UTR2135356..2135328PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00164 Pfam IPR006032 Ribosomal protein S12/S23 9 142 3
PS00055 Prosite Patterns IPR006032 Ribosomal protein S12/S23 60 67 3
PTHR11652 HMMPANTHER IPR006032 Ribosomal protein S12/S23 1 142 3
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 20 141 48
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 21 141 57
PIRSF002133 PIRSF IPR006032 Ribosomal protein S12/S23 6 143 3
TIGR00982 tigrfam IPR005680 Ribosomal protein S23, eukaryotic/archaeal 6 142 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.48 Da
Charge 20.50
Isoelectric point 11.05
Molecular weight 15.66 kDa
Number of residues 143
Modifications

Protein Modifications

Term IDTerm NameEvidenceResidueReferenceCount
MOD:00046O-phospho-L-serineS38PMID:247631071669
present during mitotic M phaseS44PMID:21712547
present during mitotic M phaseS38PMID:21712547
present during mitotic M phaseS39PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
155266during GO:0000080PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
169078during GO:0000084PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
145565during GO:0000085PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
179853during GO:0000087PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
152021during GO:0072690PECO:0000005,
PECO:0000126
mass spectrometry evidencePMID:24763107
NDduring GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
69during GO:0072690PECO:0000014,
PECO:0000005
experimental evidencePMID:23101633
6.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000014,
PECO:0000127,
PECO:0000005
experimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4569
conserved in eukaryotes4482
conserved in bacteria1001
conserved in metazoa3419
conserved in vertebrates3393
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
duo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
cdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Negative GeneticPMID:22681890
mid1medial ring protein Mid1 Negative GeneticPMID:22681890
srp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
rok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
elp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
SPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
snf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
sty1MAP kinase Sty1 Negative GeneticPMID:22681890
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:22681890
ask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
swi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
ptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
dsk1SR protein-specific kinase Dsk1 Negative GeneticPMID:22681890
pmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
swc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
sgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
cph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:22681890
ptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
msd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
csn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
spc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
ngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
nup61nucleoporin Nup61 Negative GeneticPMID:22681890
reb1RNA polymerase I transcription termination factor Reb1 Positive GeneticPMID:22681890
srb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:22681890
pab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
dsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
SPAC1486.03cRNA-binding splicing factor (predicted) Positive GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
fhl1forkhead transcription factor Fhl1 Negative GeneticPMID:22681890
dam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC23C11.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC23C11.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC23C11.02c BioGRID Interaction Datasets
Expression Viewer SPAC23C11.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC23C11.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC23C11.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC23C11.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC23C11.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC23C11.02c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC23C11.02c Cell Cycle Data
GEO SPAC23C11.02c GEO profiles
PInt SPAC23C11.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC23C11.02c Peptides identified in tandem mass spectrometry proteomics experiments
WikiGene254201240S ribosomal protein S23
WikiGene254136940S ribosomal protein S23
EntrezGene254201240S ribosomal protein S23
EntrezGene254136940S ribosomal protein S23
SPD / RIKEN03/03E10Orfeome Localization Data
UniProtKB/SwissProtP7905740S ribosomal protein S23
ModBaseP79057Database of comparative protein structure models
STRINGP79057Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59363340S ribosomal protein S23
RefSeq mRNANM_001019064972h- 40S ribosomal protein S23 (rps23), mRNA
European Nucleotide ArchiveAB001288ENA EMBL mapping
European Nucleotide ArchiveBAA19233ENA Protein Mapping
European Nucleotide ArchiveCAB11155ENA Protein Mapping
European Nucleotide ArchiveCAB11155.1ENA Protein Mapping
European Nucleotide ArchiveCAB83171ENA Protein Mapping
European Nucleotide ArchiveCAB83171.1ENA Protein Mapping
ReactomeREACT_188294
ReactomeREACT_188542
ReactomeREACT_188560
ReactomeREACT_206850
ReactomeREACT_210923
ReactomeREACT_215930
ReactomeREACT_226552
UniParcUPI0000134E9AUniProt Archive

Literature for rps23

Search: Europe PMC or PubMed

Release Version: PomBase:22_45 - 08 Aug 2014