rps23 (SPAC23C11.02c)


Gene Standard Namerps23 Characterisation Statusbiological_role_inferred
Systematic IDSPAC23C11.02c Feature Typeprotein coding
Synonyms Name Description
Product40S ribosomal protein S23 (predicted) Product Size143aa, 15.66 kDa
Genomic Location Chromosome I, 2135841-2135328 (514nt); CDS:2135788-2135357 (432nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
structural constituent of ribosome255
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
cytoplasmic translation459
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
cytosolic small ribosomal subunit65
Annotation ExtensionEvidenceWith/FromReference
nucleolus359
Annotation ExtensionEvidenceWith/FromReference
nucleus2695
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
sensitive to cobaltrps23ΔNull56
slow vegetative cell population growthrps23ΔNull326
viable vegetative cell populationrps23ΔNull3795

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologyrps23ΔNull3093
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2135841..2135328
mRNA2135841..2135328
5' UTR2135841..2135789PMID:21511999
CDS2135788..2135357
3' UTR2135356..2135328PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF00164 Pfam IPR006032 Ribosomal protein S12/S23 9 142 3
PS00055 Prosite Patterns IPR006032 Ribosomal protein S12/S23 60 67 3
PTHR11652 HMMPANTHER IPR006032 Ribosomal protein S12/S23 1 142 3
2.40.50.140 Gene3D IPR012340 Nucleic acid-binding, OB-fold 20 141 48
SSF50249 SuperFamily IPR012340 Nucleic acid-binding, OB-fold 21 141 57
PIRSF002133 PIRSF IPR006032 Ribosomal protein S12/S23 6 143 3
TIGR00982 tigrfam IPR005680 Ribosomal protein S23, eukaryotic/archaeal 6 142 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 109.48 Da
Charge 20.50
Isoelectric point 11.05
Molecular weight 15.66 kDa
Number of residues 143
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serineS38 1672
present during mitotic M phaseS39
present during mitotic M phaseS44
present during mitotic M phaseS38
Annotation ExtensionEvidenceResidueReference
experimental evidence S38 PMID:24763107
present during mitotic M phase experimental evidence S38 PMID:21712547
present during mitotic M phase experimental evidence S39 PMID:21712547
present during mitotic M phase experimental evidence S44 PMID:21712547
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
155266during GO:0000080PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
169078during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
145565during GO:0000085PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
179853during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
152021during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
69during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
6.4during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4604
conserved in eukaryotes4516
conserved in bacteria1000
conserved in metazoa3430
conserved in vertebrates3405
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withask1DASH complex subunit Ask1 Negative GeneticPMID:22681890
negative genetic interaction withcdr1NIM1 family serine/threonine protein kinase Cdr1/Nim1 Negative GeneticPMID:22681890
negative genetic interaction withcph2Clr6 histone deacetylase associated PHD protein-2 Cph2 Negative GeneticPMID:22681890
negative genetic interaction withcsn1COP9/signalosome complex subunit Csn1 Negative GeneticPMID:22681890
negative genetic interaction withdam1DASH complex subunit Dam1 Negative GeneticPMID:22681890
negative genetic interaction withdsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:22681890
negative genetic interaction withdsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:22681890
negative genetic interaction withdsc4Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:22681890
negative genetic interaction withdsk1SR protein-specific kinase Dsk1 Negative GeneticPMID:22681890
negative genetic interaction withduo1DASH complex subunit Duo1 Negative GeneticPMID:22681890
positive genetic interaction withelp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
positive genetic interaction withelp3elongator complex subunit Elp3 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withfhl1forkhead transcription factor Fhl1 Negative GeneticPMID:22681890
negative genetic interaction withmid1medial ring protein Mid1 Negative GeneticPMID:22681890
negative genetic interaction withmsd1mitotic-spindle disanchored Msd1 Negative GeneticPMID:22681890
negative genetic interaction withmug154conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withngg1SAGA complex subunit Ngg1 Negative GeneticPMID:22681890
negative genetic interaction withnup61nucleoporin Nup61 Negative GeneticPMID:22681890
negative genetic interaction withpab2poly(A) binding protein Pab2 Negative GeneticPMID:22681890
positive genetic interaction withpef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
negative genetic interaction withpmc2mediator complex subunit Pmc2/Med1 Negative GeneticPMID:22681890
negative genetic interaction withptc1protein phosphatase 2C Ptc1 Negative GeneticPMID:22681890
negative genetic interaction withptc2protein phosphatase 2C Ptc2 Negative GeneticPMID:22681890
positive genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Positive GeneticPMID:22681890
positive genetic interaction withrok1ATP-dependent RNA helicase Rok1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withsgf29SAGA complex subunit Sgf29 Negative GeneticPMID:22681890
negative genetic interaction withsnf5SWI/SNF complex subunit Snf5 Negative GeneticPMID:22681890
positive genetic interaction withSPAC1486.03cRNA-binding splicing factor (predicted) Positive GeneticPMID:22681890
negative genetic interaction withSPBC56F2.08cRNA-binding protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspc34DASH complex subunit Spc34 Negative GeneticPMID:22681890
negative genetic interaction withsrb11cyclin CycC, Srb mediator subunit Srb11 Negative GeneticPMID:22681890
negative genetic interaction withsrp1SR family protein, human SRFS2 ortholog Srp1 Negative GeneticPMID:22681890
negative genetic interaction withssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsty1MAP kinase Sty1 Negative GeneticPMID:22681890
positive genetic interaction withswc5Swr1 complex subunit Swc5 Positive GeneticPMID:22681890
negative genetic interaction withswi6HP1 family chromodomain protein Swi6 Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC23C11.02c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC23C11.02c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC23C11.02c BioGRID Interaction Datasets
Expression Viewer SPAC23C11.02c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC23C11.02c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC23C11.02c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC23C11.02c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC23C11.02c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC23C11.02c Transcriptome Viewer (Bähler Lab)
GEO SPAC23C11.02c GEO profiles
PInt SPAC23C11.02c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC23C11.02c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC23C11.02c Fission yeast phenotypic data & analysis
Cyclebase SPAC23C11.02c.1 Cell Cycle Data
SPD / RIKEN03/03E10Orfeome Localization Data
UniProtKB/SwissProtP7905740S ribosomal protein S23
ModBaseP79057Database of comparative protein structure models
STRINGP79057Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_59363340S ribosomal protein S23
RefSeq mRNANM_001019064972h- 40S ribosomal protein S23 (rps23), mRNA
European Nucleotide ArchiveAB001288ENA EMBL mapping
European Nucleotide ArchiveCAB11155.1ENA Protein Mapping
European Nucleotide ArchiveCAB83171.1ENA Protein Mapping
UniParcUPI0000134E9AUniProt Archive

Literature for rps23

Search: Europe PMC or PubMed

Release Version: PomBase:26_51 - 07 Apr 2015