pst2 (SPAC23C11.15)


Gene Standard Namepst2 Characterisation Statuspublished
Systematic IDSPAC23C11.15 Feature Typeprotein coding
Synonyms Name Description
ProductClr6 histone deacetylase complex subunit Pst2 Product Size1075aa, 124.85 kDa
Genomic Location Chromosome I, 2160354-2164078 (3725nt); CDS:2160572-2163923 (3352nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
protein binding859
Annotation ExtensionEvidenceWith/FromReference
transcription corepressor activity5
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
chromatin remodeling155
Annotation ExtensionEvidenceWith/FromReference
chromatin silencing112
Annotation ExtensionEvidenceWith/FromReference
histone deacetylation26
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
nucleus2696
Annotation ExtensionEvidenceWith/FromReference
Rpd3S complex16
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
decreased mating efficiencypst2ΔNull252
increased number of cells with 1C DNA contentpst2ΔNull40
sensitive to 5-fluorouracilpst2ΔNull271
sensitive to bleomycinpst2ΔNull75
sensitive to camptothecinpst2ΔNull225
sensitive to hydroxyureapst2ΔNull534
sensitive to methyl methanesulfonatepst2ΔNull239
sensitive to thiabendazolepst2ΔNull219
sensitive to UV during vegetative growthpst2ΔNull142
viable vegetative cell populationpst2ΔNull3809
unnamed (unrecorded)

Cell Phenotype

Term NameAlleleExpressionCount
abnormal mitotic cell cycle arrest with unreplicated DNApst2ΔNull50
elongated telomerespst2ΔNull169
viable vegetative cell with normal cell morphologypst2ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons2160354..2160602, 2160649..2160829, 2160908..2164078
mRNA2160354..2164078
5' UTR2160354..2160571PMID:21511999
CDS2160572..2160602, 2160649..2160829, 2160908..2163923
3' UTR2163924..2164078PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF08295 Pfam IPR013194 Histone deacetylase interacting 335 433 3
PF02671 Pfam IPR003822 Paired amphipathic helix 168 206 3
PF02671 Pfam IPR003822 Paired amphipathic helix 272 312 3
PF02671 Pfam IPR003822 Paired amphipathic helix 54 100 3
SM00761 SMART IPR013194 Histone deacetylase interacting 333 434 3
PS51477 Prosite Profiles IPR003822 Paired amphipathic helix 28 102 3
PS51477 Prosite Profiles IPR003822 Paired amphipathic helix 243 319 3
PS51477 Prosite Profiles IPR003822 Paired amphipathic helix 138 208 3
PTHR12346 HMMPANTHER 42 1052 3
PTHR12346:SF0 HMMPANTHER 42 1052 3
1g1eB00 Gene3D IPR003822 Paired amphipathic helix 41 101 3
1g1eB00 Gene3D IPR003822 Paired amphipathic helix 138 207 3
1g1eB00 Gene3D IPR003822 Paired amphipathic helix 255 312 3
SSF47762 SuperFamily IPR003822 Paired amphipathic helix 34 100 3
SSF47762 SuperFamily IPR003822 Paired amphipathic helix 254 313 3
SSF47762 SuperFamily IPR003822 Paired amphipathic helix 135 206 3

View domain organization at Pfam

Manually Curated Family or Sub-families

Term IDTerm NameReferenceCount
PBO:0001382SIN3 family co-repressorTemporary processing gif - replaced by AJAX with count of genes annotated with the term PBO:0001382

Protein Properties

Ave. residue weight 116.14 Da
Charge 15.00
Isoelectric point 8.02
Molecular weight 124.85 kDa
Number of residues 1075
Modifications

Protein Modifications

Term NameResidueCount
O-phospho-L-serine 1672
present during mitotic M phaseS881
present during mitotic M phaseS641
present during mitotic M phaseS687
present during mitotic M phaseS643
present during mitotic M phaseS28
S643
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence S28 PMID:21712547
present during mitotic M phase experimental evidence S641 PMID:21712547
experimental evidence S643 PMID:24763107
present during mitotic M phase experimental evidence S643 PMID:21712547
present during mitotic M phase experimental evidence S687 PMID:21712547
present during mitotic M phase experimental evidence S881 PMID:21712547
O-phospho-L-threonine 698
present during mitotic M phaseT32
Annotation ExtensionEvidenceResidueReference
present during mitotic M phase experimental evidence T32 PMID:21712547
phosphorylated residue 1927
Annotation ExtensionEvidenceResidueReference
IDA PMID:19547744
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2987during GO:0000084PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
2922during GO:0000087PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
900.26during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
3022during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107
827.21during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
2.4during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.95during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi4603
conserved in eukaryotes4514
conserved in metazoa3424
conserved in vertebrates3399
conserved in eukaryotes only2501
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Physical Interactions

Source: BioGRID

View all interactions in esyN
View the HCPIN interactions in esyN

Gene Product Evidence Reference
affinity captured byalp13MRG family Clr6 histone deacetylase complex subunit Alp13 Affinity Capture-WesternPMID:12773392
affinity captured byclr6histone deacetylase (class I) Clr6 Affinity Capture-WesternPMID:12773392
affinity captured byprw1Clr6 histone deacetylase complex subunit Prw1 Affinity Capture-WesternPMID:12773392
Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
negative genetic interaction withabc3ABC transmembrane transporter Abc3, unknown specificity Negative GeneticPMID:22681890
negative genetic interaction withabc4glutathione S-conjugate-exporting ATPase Abc4 Negative GeneticPMID:22681890
enhances phenotype ofakr1palmitoyltransferase Akr1 (predicted) Phenotypic EnhancementPMID:19547744
negative genetic interaction withalb1pre-60S shuttling factor Alb1 (predicted) Negative GeneticPMID:22681890
enhances phenotype ofalg5dolichyl-phosphate beta-glucosyltransferase Alg5 (predicted) Phenotypic EnhancementPMID:19547744
enhances phenotype ofalp31tubulin specific chaperone cofactor A, Alp31 Phenotypic EnhancementPMID:19547744
negative genetic interaction withape2aminopeptidase Ape2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withapm3AP-3 adaptor complex subunit Apm3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withare2acyl-coA-sterol acyltransferase Are2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction witharg6acetylglutamate synthase Arg6 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withash2Ash2-trithorax family protein Negative GeneticPMID:22681890
enhances phenotype ofash2Ash2-trithorax family protein Phenotypic EnhancementPMID:19547744
negative genetic interaction withatb2tubulin alpha 2 Negative GeneticPMID:22681890
negative genetic interaction withatg7E1 Atg8 and Atg12 E1 activating enzyme Atg7 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withatp12mitochondrial F1-ATPase chaperone Atp12 (predicted) Negative GeneticPMID:22681890
rescuesaut12autophagy associated protein Aut12 (predicted) Phenotypic SuppressionPMID:19547744
negative genetic interaction withbio2biotin synthase Negative GeneticPMID:22681890
negative genetic interaction withbqt4bouquet formation protein Bqt4 Negative GeneticPMID:22681890
positive genetic interaction withcaf5spermine family transmembrane transporter Caf5 Positive GeneticPMID:22681890
negative genetic interaction withcek1serine/threonine protein kinase Cek1 Negative GeneticPMID:22681890
positive genetic interaction withcip2RNA-binding protein Cip2 Positive GeneticPMID:22681890
negative genetic interaction withcis4cation diffusion family zinc transmembrane transporter Cis4 Negative GeneticPMID:22681890
enhances phenotype ofcis4cation diffusion family zinc transmembrane transporter Cis4 Phenotypic EnhancementPMID:19547744
rescued byckb2CK2 family regulatory subunit Ckb2 (predicted) Phenotypic SuppressionPMID:19547744
negative genetic interaction withclp1Cdc14-related protein phosphatase Clp1/Flp1 Negative GeneticPMID:22681890
negative genetic interaction withclr1SHREC complex subunit Clr1 Negative GeneticPMID:22681890
negative genetic interaction withclr5Clr5 protein Negative GeneticPMID:22681890
phenotype enhanced bycnp1centromere-specific histone H3 CENP-A Phenotypic EnhancementPMID:23028377
rescuescnp3CENP-C ortholog Cnp3 Phenotypic SuppressionPMID:19758558
enhances phenotype ofcoq7ubiquinone biosynthesis protein Coq7 Phenotypic EnhancementPMID:19547744
rescuescph1Clr6 histone deacetylase associated PHD protein-1 Cph1 Phenotypic SuppressionPMID:19547744
negative genetic interaction withctl1choline transmembrane transporter family protein Ctl1 Negative GeneticPMID:22681890
negative genetic interaction withctu2cytosolic thiouridylase subunit Ctu2 Negative GeneticPMID:22681890
negative genetic interaction withdcd1deoxycytidylate deaminase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withdlc1dynein light chain Dlc1 Negative GeneticPMID:22681890
positive genetic interaction withdph2diphthamide biosynthesis protein (predicted) Positive GeneticPMID:22681890
enhances phenotype ofelp6elongator complex subunit Elp6 (predicted) Phenotypic EnhancementPMID:19547744
negative genetic interaction witherf4palmitoyltransferase complex subunit Erf4 Negative GeneticPMID:22681890
negative genetic interaction withers1RNA-silencing factor Ers1 Negative GeneticPMID:22681890
negative genetic interaction witheti1conserved fungal protein associated with stress granule Negative GeneticPMID:22681890
negative genetic interaction withexg1glucan 1,6-beta-glucosidase Exg1 Negative GeneticPMID:22681890
negative genetic interaction withfhl1forkhead transcription factor Fhl1 Negative GeneticPMID:22681890
negative genetic interaction withfin1serine/threonine protein kinase, NIMA related Fin1 Negative GeneticPMID:22681890
negative genetic interaction withfio1iron transport multicopper oxidase Fio1 Negative GeneticPMID:22681890
negative genetic interaction withfis1mitochondrial fission protein Fis1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfma1methionine aminopeptidase Fma1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfrp2ferric-chelate reductase Frp2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withfsv1SNARE Fsv1 Negative GeneticPMID:22681890
positive genetic interaction withgcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Positive GeneticPMID:22681890
rescued bygcn5SAGA complex histone acetyltransferase catalytic subunit Gcn5 Phenotypic SuppressionPMID:19547744
negative genetic interaction withgdh1NADP-specific glutamate dehydrogenase Gdh1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withgid9GID complex subunit Gid9 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withgit5heterotrimeric G protein beta subunit Git5 Positive GeneticPMID:22681890
negative genetic interaction withglo1glyoxalase I Negative GeneticPMID:22681890
positive genetic interaction withgma12alpha-1,2-galactosyltransferase Gma12 Positive GeneticPMID:22681890
rescued bygma12alpha-1,2-galactosyltransferase Gma12 Phenotypic SuppressionPMID:19547744
positive genetic interaction withgmh5alpha-1,2-galactosyltransferase (predicted) Positive GeneticPMID:22681890
negative genetic interaction withgpd2glycerol-3-phosphate dehydrogenase Gpd2 Negative GeneticPMID:22681890
negative genetic interaction withgrx3monothiol glutaredoxin Grx3 Negative GeneticPMID:22681890
negative genetic interaction withgst1glutathione S-transferase Gst1 Negative GeneticPMID:22681890
enhances phenotype ofgst1glutathione S-transferase Gst1 Phenotypic EnhancementPMID:19547744
negative genetic interaction withgti1gluconate transmembrane transporter inducer Gti1 Negative GeneticPMID:22681890
negative genetic interaction withgyp7GTPase activating protein Gyp7 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withhap2HMG box protein (predicted) Negative GeneticPMID:22681890
phenotype enhanced byhht2histone H3 h3.2 Phenotypic EnhancementPMID:19547744
rescueshmo1HMG box protein Hmo1 Phenotypic SuppressionPMID:19547744
negative genetic interaction withhnt1adenosine 5'-monophosphoramidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withies4Ino80 complex subunit Ies4 Negative GeneticPMID:22681890
negative genetic interaction withiqw1WD repeat protein, Iqw1 Negative GeneticPMID:22681890
positive genetic interaction withivn1CDC50 domain protein, implicated in signal transduction (predicted) Positive GeneticPMID:22681890
rescuesivn1CDC50 domain protein, implicated in signal transduction (predicted) Phenotypic SuppressionPMID:19547744
negative genetic interaction withiwr1RNA polymerase II nuclear import protein Iwr1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withkap113karyopherin Kap113 Negative GeneticPMID:22681890
negative genetic interaction withklp6kinesin-like protein Klp6 Negative GeneticPMID:22681890
negative genetic interaction withlys12homoisocitrate dehydrogenase Lys12 Negative GeneticPMID:22681890
negative genetic interaction withlys4homocitrate synthase Negative GeneticPMID:22681890
negative genetic interaction withmak10NatC N-acetyltransferase complex subunit Mak10 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmca1transcription factor, zf-fungal binuclear cluster type Mca1 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withmei2RNA-binding protein involved in meiosis Mei2 Positive GeneticPMID:22681890
rescuesmex67mRNA export receptor, Tap, nucleoporin Mex67 Phenotypic SuppressionPMID:19547744
negative genetic interaction withmgr2TIM23 translocase complex subunit Mgr2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmis4adherin, cohesin loading factor Mis4 Negative GeneticPMID:23050226
positive genetic interaction withmnl1alpha mannosidase Mnl1 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withmpc1mitochondrial pyruvate transmembrane transporter subunit Mpc1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmpp6nuclear exosome-associated RNA binding protein Mpp6 Negative GeneticPMID:22681890
negative genetic interaction withmug113T5orf172 family protein Negative GeneticPMID:22681890
negative genetic interaction withmug121Schizosaccharomyces pombe specific protein Mug121 Negative GeneticPMID:22681890
negative genetic interaction withmug147Schizosaccharomyces specific protein Mug147 Negative GeneticPMID:22681890
negative genetic interaction withmug16UNC-50 family Golgi membrane protein Negative GeneticPMID:22681890
negative genetic interaction withmug65spore wall assembly protein Mug65 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withmug94Schizosaccharomyces pombe specific protein Mug94 Negative GeneticPMID:22681890
enhances phenotype ofngg1SAGA complex subunit Ngg1 Phenotypic EnhancementPMID:19547744
negative genetic interaction withnpp1nucleotide pyrophosphatase Npp1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withnsk1Clp1-interacting, microtubule plus-end binding Nsk1 Negative GeneticPMID:22681890
negative genetic interaction withnta1protein N-terminal amidase Nta1 (predicted) Negative GeneticPMID:22681890
enhances phenotype ofpac10prefoldin subunit 3 Pac10 (predicted) Phenotypic EnhancementPMID:19547744
negative genetic interaction withpac2cAMP-independent regulatory protein Pac2 Negative GeneticPMID:22681890
negative genetic interaction withpdp2PWWP domain protein Pdp2 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withpho1acid phosphatase Pho1 Negative GeneticPMID:22681890
negative genetic interaction withpmk1MAP kinase Pmk1 Negative GeneticPMID:22681890
negative genetic interaction withpmt1tRNA methyltransferase Pmt1 Negative GeneticPMID:22681890
negative genetic interaction withpop2F-box/WD repeat protein Pop2 Negative GeneticPMID:22681890
negative genetic interaction withppk25serine/threonine protein kinase Ppk25 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppk29Ark1/Prk1 family protein kinase Ppk29 Negative GeneticPMID:22681890
negative genetic interaction withppk8serine/threonine protein kinase Ppk8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withppr2mitochondrial PPR repeat protein Ppr2 Negative GeneticPMID:22681890
negative genetic interaction withpsh3ER chaperone SHR3 homologue Psh3 Negative GeneticPMID:22681890
negative genetic interaction withpsl1cyclin pho85 family Psl1 (predicted) Negative GeneticPMID:22681890
rescuesptl1triacylglycerol lipase ptl1 Phenotypic SuppressionPMID:19547744
negative genetic interaction withptr2PTR family peptide transmembrane transporter Ptr2 Negative GeneticPMID:22681890
phenotype enhanced bypub2HECT-type ubiquitin-protein ligase E3 Pub2 Phenotypic EnhancementPMID:19547744
positive genetic interaction withpyp1tyrosine phosphatase Pyp1 Positive GeneticPMID:22681890
negative genetic interaction withpzh1serine/threonine protein phosphatase Pzh1 Negative GeneticPMID:22681890
negative genetic interaction withqcr8ubiquinol-cytochrome-c reductase complex subunit 7 Negative GeneticPMID:22681890
negative genetic interaction withrad2FEN-1 endonuclease Rad2 Negative GeneticPMID:22681890
enhances phenotype ofrad2514-3-3 protein Rad25 Phenotypic EnhancementPMID:19547744
negative genetic interaction withraf1CLRC ubiquitin E3 ligase complex specificiy factor Raf1/Dos1 Negative GeneticPMID:22681890
negative genetic interaction withrap1telomere binding protein Rap1 Negative GeneticPMID:22681890
phenotype enhanced byrap1telomere binding protein Rap1 Phenotypic EnhancementPMID:19547744
negative genetic interaction withreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Negative GeneticPMID:22681890
enhances phenotype ofreb1RNA polymerase I transcription termination factor/ RNA polymerase II transcription factor Reb1 Phenotypic EnhancementPMID:19547744
phenotype enhanced byrec14Ski complex subunit Rec14 Phenotypic EnhancementPMID:19547744
negative genetic interaction withrev3DNA polymerase zeta catalytic subunit Rev3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrga3Rho-type GTPase activating protein Rga3 Negative GeneticPMID:22681890
negative genetic interaction withrga6Rho-type GTPase activating protein Rga6 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrng9contractile ring myosin V regulator Rng9 Negative GeneticPMID:22681890
positive genetic interaction withrpl190260S ribosomal protein L19 Positive GeneticPMID:22681890
negative genetic interaction withrpl250260S ribosomal protein L25 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpl280160S ribosomal protein L27/L28 Negative GeneticPMID:22681890
negative genetic interaction withrpl410160S ribosomal protein L41 Negative GeneticPMID:22681890
negative genetic interaction withrps170140S ribosomal protein S17 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withrps250240S ribosomal protein S25 (predicted) Positive GeneticPMID:22681890
negative genetic interaction withrps40140S ribosomal protein S4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withrpt419S proteasome regulatory subunit Rpt4 (predicted) Negative GeneticPMID:22681890
phenotype enhanced byrsc1RSC complex subunit Rsc1 Phenotypic EnhancementPMID:19547744
phenotype enhanced byrsv1transcription factor Rsv1 Phenotypic EnhancementPMID:19547744
phenotype enhanced byrsv2transcription factor Rsv2 Phenotypic EnhancementPMID:19547744
enhances phenotype ofrtn1reticulon-like protein Rtn1 Phenotypic EnhancementPMID:19547744
negative genetic interaction withscs7sphingosine hydroxylase Scs7 Negative GeneticPMID:22681890
positive genetic interaction withset1histone lysine methyltransferase Set1 Positive GeneticPMID:22681890
negative genetic interaction withshm1serine hydroxymethyltransferase Shm1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsif3Sad1 interacting factor Sif3 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withsle1eisosome assembly protein Seg1 Negative GeneticPMID:22681890
positive genetic interaction withsnf59SWI/SNF complex subunit Snf59 Positive GeneticPMID:22681890
negative genetic interaction withsno1glutamine aminotransferase subunit Sno1 (predicted) Negative GeneticPMID:22681890
rescued bysnt1Set3 complex subunit Snt1 Phenotypic SuppressionPMID:19547744
negative genetic interaction withSPAC1071.09cDNAJ domain protein, DNAJC9 family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC11D3.16cSchizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC139.01cnuclease, XP-G family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC1705.02human 4F5S homolog Negative GeneticPMID:22681890
negative genetic interaction withSPAC1805.14Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC186.06ER unfolded protein response protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC186.08cL-lactate dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC1A6.03cphospholipase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC212.01cS. pombe specific DUF999 family protein 2 Negative GeneticPMID:22681890
negative genetic interaction withSPAC212.06cDNA helicase in rearranged telomeric region, truncated Negative GeneticPMID:22681890
negative genetic interaction withSPAC22A12.17cshort chain dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC23C4.09cDNA-binding TFAR19-related protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC24H6.11csulfate transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC26H5.07cseven transmembrane receptor protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC2H10.01transcription factor, zf-fungal binuclear cluster type (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC30D11.14cRNA-binding protein (predicted) Negative GeneticPMID:22681890
enhances phenotype ofSPAC6F12.06Rho GDP dissociation inhibitor Rdi1 (predicted) Phenotypic EnhancementPMID:19547744
negative genetic interaction withSPAC750.01aldo/keto reductase family protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC750.04cS. pombe specific 5Tm protein family Negative GeneticPMID:22681890
negative genetic interaction withSPAC869.05csulfate transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC9.02cpolyamine N-acetyltransferase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAC922.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPAC977.17MIP water channel (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPACUNK4.10glyoxylate reductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAP8A3.07cphospho-2-dehydro-3-deoxyheptonate aldolase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPAPB1A11.02esterase/lipase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC115.03gfo/idh/mocA family oxidoreductase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC1348.02S. pombe specific 5Tm protein family Negative GeneticPMID:22681890
negative genetic interaction withSPBC1348.12transcription factor (predicted) Negative GeneticPMID:22681890
enhances phenotype ofSPBC16E9.02cCUE domain protein Phenotypic EnhancementPMID:19547744
negative genetic interaction withSPBC1709.16caromatic ring-opening dioxygenase (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC1773.03caminotransferase class-III, possible transaminase, unknown specificity Positive GeneticPMID:22681890
negative genetic interaction withSPBC18A7.01X-Pro dipeptidase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC18A7.02cseven transmembrane receptor-like protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC21B10.07glycosyl hydrolase family (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC21B10.08cantibiotic biosynthesis monooxygenase-like domain (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC24C6.04delta-1-pyrroline-5-carboxylate dehydrogenase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC25B2.10Usp (universal stress protein) family protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC25H2.03vacuolar protein involved in phosphoinositide metabolism (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC29A10.16ccytochrome b5 (predicted) Negative GeneticPMID:22681890
positive genetic interaction withSPBC2D10.04arrestin Aly1 related, implicated in endocytosis Positive GeneticPMID:22681890
negative genetic interaction withSPBC577.11DUF3074 family protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC651.04Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC6B1.03cPal1 family protein Negative GeneticPMID:22681890
negative genetic interaction withSPBC8E4.05cfumarate lyase superfamily Negative GeneticPMID:22681890
negative genetic interaction withSPBC947.06cspermidine family transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBC9B6.03zf-FYVE type zinc finger protein Negative GeneticPMID:22681890
negative genetic interaction withSPBCPT2R1.01cS. pombe specific DUF999 protein family 9 Negative GeneticPMID:22681890
negative genetic interaction withSPBP35G2.14RNA-binding protein Negative GeneticPMID:22681890
negative genetic interaction withSPBPB10D8.01cysteine transmembrane transporter (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.07cS. pombe specific DUF999 protein family 7 Negative GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.11nucleotide-sugar 4,6-dehydratase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPBPB2B2.17cS. pombe specific 5Tm protein family Negative GeneticPMID:22681890
negative genetic interaction withSPCC1020.05phosphoprotein phosphatase involved in unfolded protein response (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1235.01Schizosaccharomyces specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC1442.11cSchizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC1494.08cconserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC16C4.106-phosphogluconolactonase (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC1884.01Schizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC24B10.16cproteasome assembly chaperone 4 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC550.11karyopherin (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCC569.04Schizosaccharomyces pombe specific protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC61.05S. pombe specific multicopy membrane protein family 1 Negative GeneticPMID:22681890
negative genetic interaction withSPCC613.03conserved fungal protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC63.13DNAJ domain protein Negative GeneticPMID:22681890
negative genetic interaction withSPCC777.02transcription factor (predicted) Negative GeneticPMID:22681890
negative genetic interaction withSPCP20C8.02cS. pombe specific UPF0321 family protein 1 Negative GeneticPMID:22681890
negative genetic interaction withSPCP20C8.03Negative GeneticPMID:22681890
negative genetic interaction withspe1ornithine decarboxylase Spe1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withspn2mitotic and meiotic (sporulation) septin Spn2 Negative GeneticPMID:22681890
negative genetic interaction withsry1serine racemase Sry1 Negative GeneticPMID:22681890
positive genetic interaction withsub1transcription coactivator PC4 Positive GeneticPMID:22681890
negative genetic interaction withsum2G2/M transition checkpoint protein Sum2 Negative GeneticPMID:22681890
positive genetic interaction withsut1alpha-glucoside transmembrane transporter Sut1 Positive GeneticPMID:22681890
negative genetic interaction withswc3Swr1 complex subunit Swc3 Negative GeneticPMID:22681890
enhances phenotype ofswc5Swr1 complex subunit Swc5 Phenotypic EnhancementPMID:19547744
negative genetic interaction withsyn1synaptotagmin family C2 domain protein, Syn1 Negative GeneticPMID:22681890
negative genetic interaction withtax4autophagy/CVT pathway ENTH/VHS domain protein Tax4(predicted) Negative GeneticPMID:22681890
negative genetic interaction withthi5transcription factor Thi5 Negative GeneticPMID:22681890
positive genetic interaction withtht2karyogamy protein Tht2 Positive GeneticPMID:22681890
negative genetic interaction withtif512translation elongation factor eIF5A (predicted) Negative GeneticPMID:22681890
phenotype enhanced bytim13TIM22 inner membrane protein import complex subunit Tim13 (predicted) Phenotypic EnhancementPMID:19547744
negative genetic interaction withtls1splicing factor Tls1 Negative GeneticPMID:22681890
negative genetic interaction withtma20RNA-binding protein Tma20 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtrm8tRNA (guanine-N7-)-methyltransferase catalytic subunit Trm8 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withtsc1hamartin Negative GeneticPMID:22681890
positive genetic interaction withubc13ubiquitin conjugating enzyme E2 Ubc13 Positive GeneticPMID:22681890
negative genetic interaction withubc16ubiquitin conjugating enzyme E2 Ubc16 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withubp11ubiquitin C-terminal hydrolase Ubp11 Negative GeneticPMID:22681890
negative genetic interaction withuep1ribosomal-ubiquitin fusion protein Ubi2 Negative GeneticPMID:22681890
negative genetic interaction withupf1ATP-dependent RNA helicase Upf1 Negative GeneticPMID:22681890
negative genetic interaction withura1carbamoyl-phosphate synthase (glutamine hydrolyzing), aspartate carbamoyltransferase Ura1 Negative GeneticPMID:22681890
positive genetic interaction withure2urease Ure2 Positive GeneticPMID:22681890
negative genetic interaction withvac7Vac7 ortholog (predicted) Negative GeneticPMID:22681890
negative genetic interaction withvht1vitamin H transmembrane transporter Vht1 Negative GeneticPMID:22681890
negative genetic interaction withvps1301chorein homolog Vps13a (predicted) Negative GeneticPMID:22681890
enhances phenotype ofwis2cyclophilin family peptidyl-prolyl cis-trans isomerase Wis2 Phenotypic EnhancementPMID:19547744
negative genetic interaction withwos2p23 homolog, predicted co-chaperone Wos2 Negative GeneticPMID:22681890
negative genetic interaction withxan1alpha ketoglutarate dependent xanthine dioxygenase Xan1 Negative GeneticPMID:22681890
negative genetic interaction withyap18ENTH/VHS domain protein (predicted) Negative GeneticPMID:22681890
negative genetic interaction withyar1ribosome biogenesis protein Yar1 (predicted) Negative GeneticPMID:22681890
negative genetic interaction withzrg17cation diffusion family zinc transmembrane transporter Zrg17 Negative GeneticPMID:22681890
negative genetic interaction withzwf2glucose-6-phosphate 1-dehydrogenase Zwf2 (predicted) Negative GeneticPMID:22681890
External References
Database Identifier Description
NBRP SPAC23C11.15 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC23C11.15 Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC23C11.15 BioGRID Interaction Datasets
Expression Viewer SPAC23C11.15 Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC23C11.15 Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC23C11.15 Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC23C11.15 Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC23C11.15 Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC23C11.15 Transcriptome Viewer (Bähler Lab)
GEO SPAC23C11.15 GEO profiles
PInt SPAC23C11.15 Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC23C11.15 Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC23C11.15 Fission yeast phenotypic data & analysis
Cyclebase SPAC23C11.15.1 Cell Cycle Data
SPD / RIKEN48/48C01Orfeome Localization Data
UniProtKB/SwissProtO13919Paired amphipathic helix protein pst2
ModBaseO13919Database of comparative protein structure models
STRINGO13919Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_593646Clr6 histone deacetylase complex subunit Pst2
RefSeq mRNANM_001019077972h- Clr6 histone deacetylase complex subunit Pst2 (pst2), mRNA
European Nucleotide ArchiveCAB11171.1ENA Protein Mapping
UniParcUPI000013281CUniProt Archive

Literature for pst2

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Release Version: PomBase:26_52 - 11 May 2015