ssr3 (SPAC23G3.10c)

Gene Standard Namessr3 ChromosomeI
Systematic IDSPAC23G3.10c Gene Start887531
Synonyms Gene End884513
ProductSWI/SNF and RSC complex subunit Ssr3 Gene Length3019
Feature Typeprotein coding CDS Start887172
Name DescriptionSwi/Snf RSC CDS End885895
Characterisation Statuspublished CDS Length1278

Ensembl Gene Location
  1. SPAC23G3.06
  2. snf30
  3. ubp7
  4. taf4
  5. ssr3
  6. rpn6
  7. SPAC23G3.12c
  8. mug35
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopyssr3delta (deletion)deletionPMID:20473289
FYPO:0002061inviable vegetative cell populationssr3delta (deletion)deletionPMID:18622392
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0000991core RNA polymerase II binding transcription factor activityISOSGD:S000005306GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0006338chromatin remodelingISOSGD:S000005306GO_REF:0000024
GO:0006357regulation of transcription from RNA polymerase II promoterICGO:0016514GO_REF:0000001
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0000790nuclear chromatinICGO:0016586GO_REF:0000001
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
GO:0016514SWI/SNF complexIDAPMID:18622392
GO:0016586RSC complexIDAPMID:18622392
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1887531884513

References

Region Start End Reference
three_prime_UTR885894884513PMID:21511999
five_prime_UTR887531887173PMID:21511999
three_prime_UTR885894884513PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02201 IPR003121 Pfam SWIB/MDM2 domain 203 276 2
G3DSA:1.10.245.10 Gene3D 196 287 2
SSF47592 IPR003121 SuperFamily 196 287 2
PTHR13844 hmmpanther 3 416 2
PTHR13844:SF0 hmmpanther 3 416 2

View domain organization at Pfam

Protein Properties

Ave. residue weight 117.08 Da
Charge -7.50
Isoelectric point 5.28
Molecular weight 49.76 kDa
Number of residues 425
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide5659.28PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide5445.15PMID:23101633
RNA levelexperimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide3.6PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.92PMID:23101633
Species Distribution
DescriptionQualifierReference
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
alp13MRG family Clr6 histone deacetylase complex subunit Alp13 Phenotypic SuppressionPMID:19547744
gda1guanosine-diphosphatase Gda1 Positive GeneticPMID:22681890
vps71Swr1 complex subunit Vps71 Positive GeneticPMID:18818364
hrp3ATP-dependent DNA helicase Hrp3 Positive GeneticPMID:18818364
SPCC162.11curidine kinase/uracil phosphoribosyltransferase (predicted) Negative GeneticPMID:22681890
prp4serine/threonine protein kinase Prp4 Positive GeneticPMID:22681890
elp2elongator complex subunit Elp2 (predicted) Positive GeneticPMID:22681890
tom70mitochondrial TOM complex subunit Tom70 (predicted) Positive GeneticPMID:22681890
tma23ribosome biogenesis protein Tma23 (predicted) Positive GeneticPMID:18818364
hip1hira protein, histone chaperone Hip1 Negative GeneticPMID:18818364
hrr1Helicase Required for RNAi-mediated heterochromatin assembly Hrr1 Negative GeneticPMID:22681890
atp11F1-ATPase chaperone Atp11 (predicted) Positive GeneticPMID:22681890
mug154conserved fungal protein Negative GeneticPMID:22681890
cid12poly(A) polymerase Cid12 Negative GeneticPMID:18818364
rsv2transcription factor Rsv2 Positive GeneticPMID:22681890
scs7sphingosine hydroxylase Scs7 Positive GeneticPMID:18818364
ase1antiparallel microtubule cross-linking factor Ase1 Negative GeneticPMID:22681890
SPCC1919.05Ski complex TPR repeat subunit Ski3 (predicted) Positive GeneticPMID:22681890
raf1Rik1-associated factor Raf1 Negative GeneticPMID:22681890
SPAC1486.03cRNA-binding splicing factor (predicted) Positive GeneticPMID:22681890
pyp1tyrosine phosphatase Pyp1 Positive GeneticPMID:22681890
mug58GLYK family kinase of unknown specificity (predicted) Negative GeneticPMID:18818364
sfp1transcription factor Sfp1 (predicted) Positive GeneticPMID:22681890
ufd2ubiquitin-protein ligase E4 (predicted) Negative GeneticPMID:22681890
rad51RecA family recombinase Rad51/Rhp51 Positive GeneticPMID:22681890
cpd1tRNA (m1A) methyltransferase complex catalytic subunit Cpd1 Positive GeneticPMID:22681890
psl1cyclin pho85 family (predicted) Positive GeneticPMID:22681890
rad57RecA family ATPase Rad57/Rhp57 Negative GeneticPMID:18818364
SPAC19B12.11czinc finger protein, human ZNF593 ortholog Positive GeneticPMID:18818364
pef1Pho85/PhoA-like cyclin-dependent kinase Pef1 Positive GeneticPMID:22681890
SPBC18H10.05WD repeat protein, human WDR44 family Negative GeneticPMID:22681890
exo1exonuclease I Exo1 Positive GeneticPMID:18818364
ubp4ubiquitin C-terminal hydrolase Ubp4 Negative GeneticPMID:22681890
hip4histone promoter control protein Hip4 Negative GeneticPMID:18818364
raf2Rik1-associated factor Raf2 Negative GeneticPMID:22681890
ssp2serine/threonine protein kinase Ssp2 Positive GeneticPMID:22681890
tas3RITS complex subunit 3 Positive GeneticPMID:22681890
Physical Interactions

Source: BioGRID

Gene Product Evidence Reference
sfh1RSC complex subunit Sfh1 Affinity Capture-MSPMID:18622392
rsc7RSC complex subunit Rsc7 Affinity Capture-MSPMID:18622392
snf21ATP-dependent DNA helicase Snf21 Affinity Capture-MSPMID:18622392
cbf11CBF1/Su(H)/LAG-1 family transcription factor Cbf11 Affinity Capture-MSPMID:22540037
snf59SWI/SNF complex subunit Snf59 Affinity Capture-MSPMID:18622392
rsc1RSC complex subunit Rsc1 Affinity Capture-MSPMID:18622392
snf5SWI/SNF complex subunit Snf5 Affinity Capture-MSPMID:18622392
snf30SWI/SNF complex subunit Snf30 Affinity Capture-MSPMID:18622392
snf22ATP-dependent DNA helicase Snf22 Affinity Capture-MSPMID:18622392
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External References
Database Identifier Description
NBRP SPAC23G3.10c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC23G3.10c Retrieval of eukaryotic orthologs
BioGrid SPAC23G3.10c BioGRID Interaction Datasets
Bähler Lab SPAC23G3.10c Cell Cycle Expression Profile
Bähler Lab SPAC23G3.10c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC23G3.10c Pheromone response/mating expression profiles
Bähler Lab SPAC23G3.10c Environmental stress expression profiles
Bähler Lab SPAC23G3.10c Bähler Lab Transcriptome Viewer
Cyclebase SPAC23G3.10c Cell Cycle Data
PInt SPAC23G3.10c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC23G3.10c Entrez Gene
WikiGene2541438SWI/SNF and RSC complex subunit Ssr3
Uniprot_genenameSSR3
EntrezGene2541438SWI/SNF and RSC complex subunit Ssr3
SPD / RIKEN32/32G05Orfeome Localization Data
UniProtKB/SwissProtQ9P7S3SWI/SNF and RSC complexes subunit ssr3
ModBaseQ9P7S3Database of comparative protein structure models
Pfam Protein DomainsQ9P7S3Pfam Domain Arrangement
RefSeq PeptideNP_593110SWI/SNF and RSC complex subunit Ssr3
RefSeq mRNANM_001018507972h- SWI/SNF and RSC complex subunit Ssr3 (ssr3), mRNA
European Nucleotide ArchiveCAB72235ENA Protein Mapping
UniParcUPI000006B7BEUniProt Archive

Literature for ssr3
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013