mpc2 (SPAC24B11.09)

Gene Standard Namempc2 ChromosomeI
Systematic IDSPAC24B11.09 Gene Start214093
Synonyms Gene End216962
Productmitochondrial pyruvate transmembrane transporter subunit Mpc2 Gene Length2870
Feature Typeprotein coding CDS Start216483
Name Description CDS End216839
Characterisation Statusbiological_role_inferred CDS Length357

Ensembl Gene Location
  1. sty1
  2. SPNCRNA.622
  3. SPAC24B11.07c
  4. SPAC24B11.08c
  5. SPNCRNA.623
  6. SPNCRNA.142
  7. mpc2
  8. cfh1
  9. sid2
Fission Yeast Phenotype Ontology

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0001491viable vegetative cellMicroscopympc2delta (deletion)deletionPMID:20473289
GO Molecular Function

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0050833pyruvate transmembrane transporter activity
contributes_toISOSGD:S000003475GO_REF:0000024
GO Biological Process

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0006850mitochondrial pyruvate transportISOSGD:S000003475GO_REF:0000024
GO Cellular Component

Ontology Graph

Contact Curators
Term IDTerm NameEvidenceWith/FromReference
GO:0005737cytoplasmIDAPMID:16823372
GO:0031305integral to mitochondrial inner membraneISOSGD:S000003475GO_REF:0000024
Transcript
Contact Curators
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
1214093216962

References

Region Start End Reference
five_prime_UTR214093216482PMID:21511999
Protein Features
Contact Curators

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF03650 IPR005336 Pfam Uncharacterised protein family UPF0041 1 113 2
TMhelix TMHMM 72 94 955
PTHR14154 hmmpanther 1 110 2
PTHR14154:SF2 hmmpanther 1 110 1

View domain organization at Pfam

Protein Properties

Ave. residue weight 114.71 Da
Charge 13.00
Isoelectric point 11.51
Molecular weight 13.54 kDa
Number of residues 118
Sequence
Contact Curators
Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide2971.31PMID:23101633
experimental evidencevegetative growth of a single-celled organismPECO:0000005,
PECO:0000014		population_widePMID:23101633
RNA levelexperimental evidencevegetative growth of a single-celled organismPECO:0000014,
PECO:0000005		population_wide12PMID:23101633
experimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide1.3PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in eukaryotes only
Manually curated orthologous groups
SpeciesGeneDescription

Contact Curators
Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
dsc2Golgi Dsc E3 ligase complex subunit Dsc2 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
air1zinc knuckle TRAMP complex subunit Air1 Negative GeneticPMID:22681890
epe1Jmjc domain chromatin associated protein Epe1 Negative GeneticPMID:22681890
ppk16serine/threonine protein kinase Ppk16 (predicted) Positive GeneticPMID:22681890
php3CCAAT-binding factor complex subunit Php3 Negative GeneticPMID:22681890
jmj4Jmj4 protein (predicted) Positive GeneticPMID:22681890
sre2membrane-tethered transcription factor (predicted) Negative GeneticPMID:22681890
Negative GeneticPMID:21504829
ypa2protein phosphatase type 2A regulator, PTPA family Ypa2 Negative GeneticPMID:22681890
dsc3Golgi Dsc E3 ligase complex subunit Dsc3 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
cdk11serine/threonine protein kinase cdk11 Negative GeneticPMID:22681890
dsc1Golgi Dsc E3 ligase complex subunit Dsc1 Negative GeneticPMID:21504829
Negative GeneticPMID:22681890
pek1MAP kinase kinase Pek1 Negative GeneticPMID:22681890
rik1silencing protein Rik1 Positive GeneticPMID:22681890
php5CCAAT-binding factor complex subunit Php5 Negative GeneticPMID:22681890
ssu72phosphoric ester hydrolase Ssu72 (predicted) Negative GeneticPMID:22681890
kin1microtubule affinity-regulating kinase Kin1 Negative GeneticPMID:22681890
ubp4ubiquitin C-terminal hydrolase Ubp4 Negative GeneticPMID:22681890
raf2Rik1-associated factor Raf2 Positive GeneticPMID:22681890
Contact Curators
External References
Database Identifier Description
NBRP SPAC24B11.09 Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC24B11.09 Retrieval of eukaryotic orthologs
BioGrid SPAC24B11.09 BioGRID Interaction Datasets
Bähler Lab SPAC24B11.09 Cell Cycle Expression Profile
Bähler Lab SPAC24B11.09 Meiosis/Sporulation Expression Profies
Bähler Lab SPAC24B11.09 Pheromone response/mating expression profiles
Bähler Lab SPAC24B11.09 Environmental stress expression profiles
Bähler Lab SPAC24B11.09 Bähler Lab Transcriptome Viewer
Cyclebase SPAC24B11.09 Cell Cycle Data
PInt SPAC24B11.09 Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC24B11.09 Entrez Gene
WikiGene2541475hypothetical protein
EntrezGene2541475hypothetical protein
SPD / RIKEN02/02D06Orfeome Localization Data
UniProtKB/SwissProtQ09896Probable mitochondrial pyruvate carrier 1
ModBaseQ09896Database of comparative protein structure models
Pfam Protein DomainsQ09896Pfam Domain Arrangement
RefSeq PeptideNP_592846hypothetical protein SPAC24B11.09
RefSeq mRNANM_001018247972h- hypothetical protein (SPAC24B11.09), mRNA
European Nucleotide ArchiveCAA91774ENA Protein Mapping
SPD / RIKEN02/02D06Orfeome Localization Data

Literature for mpc2
Contact Curators

Search: UK PMC or PubMed

Release Version: PomBase:18.34 - 04 Apr 2013