bgs2 (SPAC24C9.07c)


Gene Standard Namebgs2 Characterisation Statuspublished
Systematic IDSPAC24C9.07c Feature Typeprotein coding
Synonymsmeu21, pgs2 Name DescriptionMeiotic Expression Upregulated
Product1,3-beta-glucan synthase subunit Bgs2 Product Size1894aa, 219.18 kDa
Genomic Location Chromosome I, 3059282-3053214 (6069nt); CDS:3059282-3053598 (5685nt)

Ensembl Gene Location
GO Molecular Function
Term NameCount
1,3-beta-D-glucan synthase activity5
Annotation ExtensionEvidenceWith/FromReference
GO Biological Process
Term NameCount
ascospore wall assembly13
Annotation ExtensionEvidenceWith/FromReference
fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process8
Annotation ExtensionEvidenceWith/FromReference
GO Cellular Component
Term NameCount
1,3-beta-D-glucan synthase complex5
Annotation ExtensionEvidenceWith/FromReference
integral component of membrane1018
Annotation ExtensionEvidenceWith/FromReference
prospore membrane28
Annotation ExtensionEvidenceWith/FromReference
Fission Yeast Phenotype Ontology
Gene Deletion Viability: Viable

Population Phenotype

Term NameAlleleExpressionCount
viable vegetative cell populationbgs2ΔNull3809

Cell Phenotype

Term NameAlleleExpressionCount
viable vegetative cell with normal cell morphologybgs2ΔNull3094
Transcript
Ensembl transcript structure with UTRs, exons and introns

Transcript Structure

Region Coordinates Reference
Exons3059282..3053214
mRNA3059282..3053214
CDS3059282..3053598
3' UTR3053597..3053214PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF14288 Pfam IPR026899 1,3-beta-glucan synthase subunit FKS1-like, domain-1 334 442 4
PF02364 Pfam IPR003440 Glycosyl transferase, family 48 843 1666 4
TMhelix TMHMM 1775 1797 959
TMhelix TMHMM 1637 1659 959
TMhelix TMHMM 1476 1498 959
TMhelix TMHMM 1708 1730 959
TMhelix TMHMM 1674 1696 959
TMhelix TMHMM 732 754 959
TMhelix TMHMM 1339 1361 959
TMhelix TMHMM 1835 1857 959
TMhelix TMHMM 602 624 959
TMhelix TMHMM 1596 1618 959
TMhelix TMHMM 703 725 959
TMhelix TMHMM 657 679 959
TMhelix TMHMM 530 552 959
TMhelix TMHMM 1394 1411 959
TMhelix TMHMM 565 587 959
TMhelix TMHMM 1503 1525 959
PTHR12741:SF7 HMMPANTHER 56 1891 4
PTHR12741 HMMPANTHER 56 1891 5

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 115.73 Da
Charge 4.50
Isoelectric point 6.71
Molecular weight 219.18 kDa
Number of residues 1894
Sequence
Gene Expression

Qualitative Gene Expression

DescriptionLevelEvidenceReference
RNA levelpresent during GO:0034293experimental evidencePMID:11069657

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
3072during GO:0072690PECO:0000126,
PECO:0000005
single cellmass spectrometry evidencePMID:24763107

RNA Level

Molecules/Cell (average)ExtensionConditionScaleEvidenceReference
1during GO:0072690PECO:0000005,
PECO:0000014
population wideexperimental evidencePMID:23101633
0.48during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi only620
conserved in fungi4603
conserved in eukaryotes4514
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

View these interactions in esyN

Gene Product Evidence Reference
enhances phenotype ofres1MBF transcription factor complex subunit Res1 Phenotypic EnhancementPMID:19547744
External References
Database Identifier Description
NBRP SPAC24C9.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC24C9.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC24C9.07c BioGRID Interaction Datasets
Expression Viewer SPAC24C9.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC24C9.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC24C9.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC24C9.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC24C9.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC24C9.07c Transcriptome Viewer (Bähler Lab)
GEO SPAC24C9.07c GEO profiles
PInt SPAC24C9.07c Protein-Protein Interaction Predictor (Bähler Lab)
PeptideAtlas SPAC24C9.07c Peptides identified in tandem mass spectrometry proteomics experiments
SYSGRO SPAC24C9.07c Fission yeast phenotypic data & analysis
Cyclebase SPAC24C9.07c.1 Cell Cycle Data
IntEnz2.4.1.34Integrated relational Enzyme database
Rhea2.4.1.34Annotated reactions database
SPD / RIKEN39/39E08Orfeome Localization Data
UniProtKB/SwissProtO139671,3-beta-glucan synthase component bgs2
ModBaseO13967Database of comparative protein structure models
STRINGO13967Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_5940321,3-beta-glucan synthase subunit Bgs2
RefSeq mRNANM_001019457972h- 1,3-beta-glucan synthase subunit Bgs2 (bgs2), mRNA
European Nucleotide ArchiveAB054305ENA EMBL mapping
European Nucleotide ArchiveCAB11264.2ENA Protein Mapping
MetaCycPWY-6773Callose biosynthesis
KEGG_Enzyme00500+2.4.1.34Starch and sucrose metabolism
UniParcUPI0000126920UniProt Archive

Literature for bgs2

Search: Europe PMC or PubMed

Release Version: PomBase:26_53 - 27 May 2015