bgs2 (SPAC24C9.07c)


Gene Standard Namebgs2 Characterisation Statuspublished
Systematic IDSPAC24C9.07c Feature Typeprotein coding
Synonymsmeu21, pgs2 Name DescriptionMeiotic Expression Upregulated
Product1,3-beta-glucan synthase subunit Bgs2 Product Size1894aa, 219.18 kDa
Genomic Location Chromosome I, 3059282-3053214 (6069nt); CDS:3059282-3053598 (5685nt)

Ensembl Gene Location
GO Molecular Function
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:00038431,3-beta-D-glucan synthase activityISSbgs1PMID:109224785
GO Biological Process
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:0030476ascospore wall assemblyIMPPMID:1092247817
GO:0034411cell wall (1->3)-beta-D-glucan biosynthetic processISSbgs1GO_REF:00000018
GO Cellular Component
Term IDTerm NameEvidenceWith/FromReferenceCount
GO:00001481,3-beta-D-glucan synthase complexIEAIPR003440GO_REF:00000025
GO:0016021integral component of membraneIEAUniProtKB-KW:KW-0812GO_REF:00000371016
GO:0005628prospore membraneIDAPMID:1106965723
Fission Yeast Phenotype Ontology

Population Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002060viable vegetative cell populationMicroscopybgs2ΔNullPMID:204732893755
Microscopybgs2ΔNullPECO:0000005, PECO:0000137PMID:23697806

Cell Phenotype

Term IDTerm NameEvidenceAlleleExpressionConditionReferenceCount
FYPO:0002177viable vegetative cell with normal cell morphologyMicroscopybgs2ΔNullPECO:0000005, PECO:0000137PMID:236978063078
penetrance FYPO_EXT:0000001
Transcript
Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
130592823053214

UTRs

Region Start End Reference
three_prime_UTR30535973053214PMID:21511999
Protein Features

Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID Database InterPro Description Start End Count
PF02364 Pfam IPR003440 Glycosyl transferase, family 48 843 1666 4
PF14288 Pfam IPR026899 1,3-beta-glucan synthase subunit FKS1-like, domain-1 334 442 4
TMhelix TMHMM 1775 1797 959
TMhelix TMHMM 1674 1696 959
TMhelix TMHMM 1708 1730 959
TMhelix TMHMM 657 679 959
TMhelix TMHMM 602 624 959
TMhelix TMHMM 1835 1857 959
TMhelix TMHMM 1476 1498 959
TMhelix TMHMM 703 725 959
TMhelix TMHMM 1394 1411 959
TMhelix TMHMM 1596 1618 959
TMhelix TMHMM 1339 1361 959
TMhelix TMHMM 1637 1659 959
TMhelix TMHMM 565 587 959
TMhelix TMHMM 732 754 959
TMhelix TMHMM 530 552 959
TMhelix TMHMM 1503 1525 959
PTHR31738 HMMPANTHER 1 1890 4
PTHR31738:SF0 HMMPANTHER 1 1890 4
Low complexity (SEG) seg 1839 1852
Low complexity (SEG) seg 1880 1894
Low complexity (SEG) seg 1774 1797
Low complexity (SEG) seg 1395 1407
Low complexity (SEG) seg 562 575
Low complexity (SEG) seg 284 298
Low complexity (SEG) seg 73 83

View domain organization at Pfam

Sequence Ontology

Term IDTerm NameReferenceCount
SO:0001812transmembrane_helix465

Protein Properties

Ave. residue weight 115.73 Da
Charge 4.50
Isoelectric point 6.71
Molecular weight 219.18 kDa
Number of residues 1894
Sequence
Gene Expression

Quantitative Gene Expression

Protein Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
NDduring cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
NDduring GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633

RNA Level

Molecules/Cell (average)DuringConditionScaleEvidenceReference
0.48during cell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127
population_wideexperimental evidencePMID:23101633
1during GO:0072690PECO:0000005,
PECO:0000014
population_wideexperimental evidencePMID:23101633
Species Distribution
DescriptionQualifierReferenceCount
conserved in fungi only603
conserved in fungi4564
conserved in eukaryotes4482
Orthologs

Manually curated orthologous groups

SpeciesGeneDescriptionLinksCount

Orthologs in Compara


Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
res1MBF transcription factor complex subunit Res1 Phenotypic EnhancementPMID:19547744
External References
Database Identifier Description
NBRP SPAC24C9.07c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC24C9.07c Retrieval of eukaryotic orthologs (Bähler Lab)
BioGrid SPAC24C9.07c BioGRID Interaction Datasets
Expression Viewer SPAC24C9.07c Cell Cycle Expression Profile (Bähler Lab)
Expression Viewer SPAC24C9.07c Meiosis/Sporulation Expression Profies (Bähler Lab)
Expression Viewer SPAC24C9.07c Pheromone response/mating expression profiles (Bähler Lab)
Expression Viewer SPAC24C9.07c Environmental stress expression profiles (Bähler Lab)
Pomb(A) SPAC24C9.07c Polyadenylation Viewer (Gullerova lab)
pombeTV SPAC24C9.07c Transcriptome Viewer (Bähler Lab)
Cyclebase SPAC24C9.07c Cell Cycle Data
GEO SPAC24C9.07c GEO profiles
PInt SPAC24C9.07c Protein-Protein Interaction Predictor (Bähler Lab)
IntEnz2.4.1.34Integrated relational Enzyme database
Rhea2.4.1.34Annotated reactions database
WikiGene25415861,3-beta-glucan synthase subunit Bgs2
EntrezGene25415861,3-beta-glucan synthase subunit Bgs2
SPD / RIKEN39/39E08Orfeome Localization Data
UniProtKB/SwissProtO139671,3-beta-glucan synthase component bgs2
ModBaseO13967Database of comparative protein structure models
StringO13967Network display of known and predicted interactions and functional associations
RefSeq PeptideNP_5940321,3-beta-glucan synthase subunit Bgs2
RefSeq mRNANM_001019457972h- 1,3-beta-glucan synthase subunit Bgs2 (bgs2), mRNA
European Nucleotide ArchiveBAB60872ENA Protein Mapping
European Nucleotide ArchiveCAB11264ENA Protein Mapping
UniParcUPI0000126920UniProt Archive

Literature for bgs2

Search: Europe PMC or PubMed

Release Version: PomBase:21_41 - 24 Feb 2014