SPAC25B8.15c

Gene Standard NameUnassigned ChromosomeI
Systematic IDSPAC25B8.15c Gene Start4187542
Synonyms Gene End4185378
Productwybutosine biosynthesis protein Tyw3 (predicted) Gene Length2165
Feature Typeprotein coding CDS Start4187225
Name Description CDS End4186512
Characterisation Statusbiological_role_inferred CDS Length714

Ensembl Gene Location
  1. SPNCRNA.968
  2. isp7
  3. SPRRNA.19
  4. mal2
  5. SPAC25B8.15c
  6. SPAC25B8.16
  7. SPAC25B8.17
  8. SPAC25B8.18
  9. loz1
Fission Yeast Phenotype Ontology

Ontology Graph

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Term IDTerm NameEvidenceAlleleAllele TypeExpressionConditionReference
FYPO:0002060viable vegetative cell populationMicroscopySPAC25B8.15cdelta (deletion)deletionPMID:20473289
GO Molecular Function

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Term IDTerm NameEvidenceWith/FromReference
GO:0008175tRNA methyltransferase activityISOSGD:S000003018GO_REF:0000024
GO Biological Process

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Term IDTerm NameEvidenceWith/FromReference
GO:0030488tRNA methylationISOSGD:S000003018GO_REF:0000024
GO:0031591wybutosine biosynthetic processISOSGD:S000003018GO_REF:0000024
GO Cellular Component

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Term IDTerm NameEvidenceWith/FromReference
GO:0005634nucleusIDAPMID:16823372
GO:0005829cytosolIDAPMID:16823372
Transcript
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Ensembl transcript structure with UTRs, exons and introns

Exons

Exon Start End
141875424185378

References

Region Start End Reference
three_prime_UTR41865114185378PMID:21511999
three_prime_UTR41865114185378PMID:21511999
five_prime_UTR41875424187226PMID:21511999
Protein Features
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Graphical View

Ensembl protein image with mapped locations of structural domains

Protein Families and Domains

Feature ID InterPro Database Description Start End All Genes
PF02676 IPR003827 Pfam tRNA wybutosine-synthesizing protein 12 216 1
SSF111278 IPR003827 SuperFamily 9 214 1
PTHR23245 hmmpanther 52 223 3

View domain organization at Pfam

Protein Modifications (PSI-MOD)

Term IDTerm NameEvidenceResidueReference
MOD:00696phosphorylated residuePMID:18257517

Protein Properties

Ave. residue weight 113.91 Da
Charge 6.00
Isoelectric point 8.59
Molecular weight 27.00 kDa
Number of residues 237
Sequence
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Gene Expression
DescriptionEvidenceDuringConditionRangeAverage per CellReference
protein levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000005,
PECO:0000014,
PECO:0000127		population_widePMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide1917.87PMID:23101633
RNA levelexperimental evidencecell quiescence following G1 arrest due to nitrogen limitationPECO:0000127,
PECO:0000014,
PECO:0000005		population_wide0.52PMID:23101633
experimental evidencesingle-celled organism vegetative growth phasePECO:0000014,
PECO:0000005		population_wide2.6PMID:23101633
Species Distribution
DescriptionQualifierReference
predominantly single copy (one to one)
conserved in fungi
conserved in eukaryotes
conserved in metazoa
conserved in vertebrates
conserved in archaea
Manually curated orthologous groups
SpeciesGeneDescription

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Genetic Interactions

Source: BioGRID

Gene Product Evidence Reference
ams2cell cycle regulated GATA-type transcription factor Ams2 Negative GeneticPMID:22681890
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External References
Database Identifier Description
NBRP SPAC25B8.15c Fission yeast strain database, National BioResource Project (Japan)
YOGY SPAC25B8.15c Retrieval of eukaryotic orthologs
BioGrid SPAC25B8.15c BioGRID Interaction Datasets
Bähler Lab SPAC25B8.15c Cell Cycle Expression Profile
Bähler Lab SPAC25B8.15c Meiosis/Sporulation Expression Profies
Bähler Lab SPAC25B8.15c Pheromone response/mating expression profiles
Bähler Lab SPAC25B8.15c Environmental stress expression profiles
Bähler Lab SPAC25B8.15c Bähler Lab Transcriptome Viewer
Cyclebase SPAC25B8.15c Cell Cycle Data
PInt SPAC25B8.15c Bähler Lab Protein-Protein Interaction Predictor
Entrez Gene SPAC25B8.15c Entrez Gene
WikiGene2542730wybutosine biosynthesis protein Tyw3
Uniprot_genenameTYW3
EntrezGene2542730wybutosine biosynthesis protein Tyw3
SPD / RIKEN08/08E01Orfeome Localization Data
UniProtKB/SwissProtQ9UTA5tRNA wybutosine-synthesizing protein 3
ModBaseQ9UTA5Database of comparative protein structure models
Pfam Protein DomainsQ9UTA5Pfam Domain Arrangement
RefSeq PeptideNP_594474kinetochore protein Mal2
RefSeq PeptideNP_594475wybutosine biosynthesis protein Tyw3
RefSeq mRNANM_001019903972h- kinetochore protein Mal2 (mal2), mRNA
RefSeq mRNANM_001019904972h- wybutosine biosynthesis protein Tyw3 (SPAC25B8.15c), mRNA
European Nucleotide ArchiveCAB61781ENA Protein Mapping
UniParcUPI000006AE53UniProt Archive

Literature for SPAC25B8.15c
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Search: UK PMC or PubMed

Release Version: PomBase:18_35 - 11 May 2013